CA2703109C - Compositions and methods for treating purpura - Google Patents

Compositions and methods for treating purpura Download PDF

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Publication number
CA2703109C
CA2703109C CA2703109A CA2703109A CA2703109C CA 2703109 C CA2703109 C CA 2703109C CA 2703109 A CA2703109 A CA 2703109A CA 2703109 A CA2703109 A CA 2703109A CA 2703109 C CA2703109 C CA 2703109C
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CA
Canada
Prior art keywords
receptor agonist
adrenergic receptor
alpha
selective
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
CA2703109A
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English (en)
French (fr)
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CA2703109A1 (en
Inventor
Stuart D. Shanler
Andrew Ondo
Original Assignee
Allergan Inc
Aclaris Therapeutics Inc
EPI Health LLC
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Publication date
Application filed by Allergan Inc, Aclaris Therapeutics Inc, EPI Health LLC filed Critical Allergan Inc
Publication of CA2703109A1 publication Critical patent/CA2703109A1/en
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Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
CA2703109A 2007-11-16 2008-11-17 Compositions and methods for treating purpura Active CA2703109C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98856407P 2007-11-16 2007-11-16
US60/988,564 2007-11-16
PCT/US2008/083774 WO2009065116A1 (en) 2007-11-16 2008-11-17 Compositions and methods for treating purpura

Publications (2)

Publication Number Publication Date
CA2703109A1 CA2703109A1 (en) 2009-05-22
CA2703109C true CA2703109C (en) 2017-07-18

Family

ID=40639204

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2703109A Active CA2703109C (en) 2007-11-16 2008-11-17 Compositions and methods for treating purpura

Country Status (19)

Country Link
US (4) US8114898B2 (https=)
EP (3) EP2818184B1 (https=)
JP (2) JP5670196B2 (https=)
KR (1) KR101577471B1 (https=)
CN (1) CN101896204B (https=)
AU (1) AU2008322411C1 (https=)
BR (1) BRPI0819075A2 (https=)
CA (1) CA2703109C (https=)
DK (1) DK2818184T3 (https=)
ES (1) ES2709120T3 (https=)
HR (1) HRP20190214T1 (https=)
HU (1) HUE042931T2 (https=)
IL (1) IL205704A (https=)
MX (1) MX2010005331A (https=)
PL (1) PL2818184T3 (https=)
PT (1) PT2818184T (https=)
SI (1) SI2818184T1 (https=)
TR (1) TR201901431T4 (https=)
WO (1) WO2009065116A1 (https=)

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IL205704A0 (en) 2010-11-30
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