CA2700410C - Treatment of proliferative disorders using antibodies to psma - Google Patents
Treatment of proliferative disorders using antibodies to psma Download PDFInfo
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- CA2700410C CA2700410C CA2700410A CA2700410A CA2700410C CA 2700410 C CA2700410 C CA 2700410C CA 2700410 A CA2700410 A CA 2700410A CA 2700410 A CA2700410 A CA 2700410A CA 2700410 C CA2700410 C CA 2700410C
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- psma
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- antigen binding
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
- Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]
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- Health & Medical Sciences (AREA)
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- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/US2008/078742 WO2009046294A2 (en) | 2007-10-03 | 2008-10-03 | Treatment of proliferative disorders using antibodies to psma |
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| WO (1) | WO2009046294A2 (enExample) |
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| AU2010249719A1 (en) | 2009-05-19 | 2012-05-31 | Aic Blab Company | Composite current collector and methods therefor |
| CA2865282A1 (en) * | 2012-02-24 | 2013-08-29 | Cornell University | Elevated psma identifies lethal prostate cancers |
| JP2015508903A (ja) * | 2012-02-28 | 2015-03-23 | コーネル ユニヴァーシティー | 前立腺癌におけるアンドロゲン活性のバイオマーカーとしてのｐｓｍａ |
| HK1211967A1 (zh) * | 2012-10-05 | 2016-06-03 | Cornell University | 雄激素抑制，前列腺特异性膜抗原和有条件增强漏洞状态的概念 |
| MA41046A (fr) * | 2014-10-10 | 2017-08-15 | Memorial Sloan Kettering Cancer Center | Thérapies liées au psma |
| CA2976360A1 (en) * | 2015-02-11 | 2016-08-18 | Aptevo Research And Development Llc | Compositions and methods for combination therapy with prostate-specific membrane antigen binding proteins |
| WO2017053469A2 (en) | 2015-09-21 | 2017-03-30 | Aptevo Research And Development Llc | Cd3 binding polypeptides |
| SG11201909513QA (en) * | 2017-04-11 | 2019-11-28 | Univ Johns Hopkins | Prodrugs of 2-pmpa for healthy tissue protection during psma-targeted cancer imaging or radiotherapy |
| WO2021076543A1 (en) | 2019-10-14 | 2021-04-22 | Aro Biotherapeutics Company | Epcam binding fibronectin type iii domains |
| AU2021266735A1 (en) * | 2020-05-05 | 2022-12-22 | Aro Biotherapeutics Company | Prostate specific membrane antigen binding fibronectin type III domains and cells comprising the same |
| MX2023000448A (es) | 2020-07-08 | 2023-04-20 | Lava Therapeutics N V | Anticuerpos que se unen a antígeno de membrana específico de la próstata (psma) y receptores de celulas t gamma-delta. |
| BR112023021318A2 (pt) | 2021-04-14 | 2023-12-19 | Aro Biotherapeutics Company | Conjugados de domínio fn3-sirna e usos dos mesmos |
| JP2024517610A (ja) | 2021-04-14 | 2024-04-23 | アロ・バイオセラピューティクス・カンパニー | Ｃｄ７１に結合するフィブロネクチンｉｉｉ型ドメイン |
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- 2008-10-03 EP EP20152859.3A patent/EP3714906A1/en active Pending
- 2008-10-03 EP EP08836466A patent/EP2209498A2/en not_active Ceased
- 2008-10-03 US US12/681,341 patent/US20100291113A1/en not_active Abandoned
- 2008-10-03 JP JP2010528161A patent/JP5951929B2/ja active Active
- 2008-10-03 WO PCT/US2008/078742 patent/WO2009046294A2/en not_active Ceased
-
2013
- 2013-10-02 JP JP2013207386A patent/JP5969446B2/ja active Active
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2014
- 2014-11-10 US US14/537,002 patent/US20150056135A1/en not_active Abandoned
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2016
- 2016-01-14 JP JP2016005363A patent/JP6054557B2/ja active Active
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2018
- 2018-04-30 US US15/966,961 patent/US20190070322A1/en not_active Abandoned
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2024
- 2024-04-19 US US18/641,102 patent/US20250058000A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP6054557B2 (ja) | 2016-12-27 |
| US20100291113A1 (en) | 2010-11-18 |
| WO2009046294A3 (en) | 2010-03-04 |
| JP5951929B2 (ja) | 2016-07-13 |
| CA2700410A1 (en) | 2009-04-09 |
| US20190070322A1 (en) | 2019-03-07 |
| JP2016147848A (ja) | 2016-08-18 |
| JP5969446B2 (ja) | 2016-08-17 |
| WO2009046294A2 (en) | 2009-04-09 |
| JP2010540657A (ja) | 2010-12-24 |
| EP3714906A1 (en) | 2020-09-30 |
| EP2209498A2 (en) | 2010-07-28 |
| EP2740490A1 (en) | 2014-06-11 |
| JP2014040450A (ja) | 2014-03-06 |
| US20150056135A1 (en) | 2015-02-26 |
| US20250058000A1 (en) | 2025-02-20 |
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