CA2621083C - Immunomodulating tumor necrosis factor receptor 25 (tnfr25) agonists, antagonists and immunotoxins - Google Patents
Immunomodulating tumor necrosis factor receptor 25 (tnfr25) agonists, antagonists and immunotoxins Download PDFInfo
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- CA2621083C CA2621083C CA2621083A CA2621083A CA2621083C CA 2621083 C CA2621083 C CA 2621083C CA 2621083 A CA2621083 A CA 2621083A CA 2621083 A CA2621083 A CA 2621083A CA 2621083 C CA2621083 C CA 2621083C
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US71208405P | 2005-08-30 | 2005-08-30 | |
| US60/712,084 | 2005-08-30 | ||
| PCT/US2006/033828 WO2007027751A2 (en) | 2005-08-30 | 2006-08-30 | Immunomodulating tumor necrosis factor receptor 25 (tnfr25) agonists, antagonists and immunotoxins |
Publications (2)
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| CA2621083A1 CA2621083A1 (en) | 2007-03-08 |
| CA2621083C true CA2621083C (en) | 2017-04-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2621083A Active CA2621083C (en) | 2005-08-30 | 2006-08-30 | Immunomodulating tumor necrosis factor receptor 25 (tnfr25) agonists, antagonists and immunotoxins |
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| ES (1) | ES2611307T3 (enExample) |
| WO (1) | WO2007027751A2 (enExample) |
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| US8128922B2 (en) | 1999-10-20 | 2012-03-06 | Johns Hopkins University | Superior molecular vaccine linking the translocation domain of a bacterial toxin to an antigen |
| US9701725B2 (en) | 2003-05-05 | 2017-07-11 | The Johns Hopkins University | Anti-cancer DNA vaccine employing plasmids encoding signal sequence, mutant oncoprotein antigen, and heat shock protein |
| AU2005322960A1 (en) | 2005-01-06 | 2006-07-13 | The Johns Hopkins University | RNA interference that blocks expression of pro-apoptotic proteins potentiates immunity induced by DNA and transfected dendritic cell vaccines |
| JP5164167B2 (ja) * | 2005-08-30 | 2013-03-13 | ユニバーシティー オブ マイアミ | 免疫調節性腫瘍壊死因子受容体２５（ｔｎｆｒ２５）のアゴニスト、アンタゴニスト及び免疫毒素 |
| US9896511B2 (en) | 2007-01-10 | 2018-02-20 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Antibodies that bind to TL1A and methods of treating inflammatory or autoimmune disease comprising administering such antibodies |
| US9085638B2 (en) | 2007-03-07 | 2015-07-21 | The Johns Hopkins University | DNA vaccine enhancement with MHC class II activators |
| NZ585559A (en) | 2007-11-13 | 2012-11-30 | Teva Biopharmaceuticals Usa Inc | Humanized antibodies against tl1a |
| US20110195048A1 (en) * | 2008-10-08 | 2011-08-11 | Podack Eckhard R | Regulation of lymphocytes and uses therefor |
| US20110229471A1 (en) | 2008-11-26 | 2011-09-22 | Cedars-Sinai Medical Center | Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease |
| US20120029472A1 (en) * | 2008-12-19 | 2012-02-02 | University Of Miami | Tnfr25 agonists to enhance immune responses to vaccines |
| DK2462165T3 (en) * | 2009-08-03 | 2016-08-29 | Univ Miami | Method for in vivo proliferation of regulatory T cells |
| EP2377883A1 (en) * | 2010-04-15 | 2011-10-19 | Universite d'Auvergne Clermont I | Antagonists for the prevention or treatment of inflammatory bowel disease, and more particularly of Crohn's disease |
| JO3375B1 (ar) * | 2010-11-08 | 2019-03-13 | Regeneron Pharma | أجسام مضادة بشرية للجين a1 الشبيه بعامل النخر الورمي (tl1a) |
| US9737612B2 (en) * | 2011-03-01 | 2017-08-22 | Novo Nordisk A/S | Antagonistic DR3 ligands |
| KR20140104344A (ko) * | 2011-05-20 | 2014-08-28 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 시크리터리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비시스 | Ｔ 세포 매개성 질병의 병증을 개선하기 위한 ｔｌ１ａ-ｄｒ３의 상호작용의 차단 및 그것의 항체 |
| BR112014007426B1 (pt) | 2011-09-30 | 2023-01-03 | Teva Pharmaceuticals Australia Pty Ltd | Anticorpos contra tl1a e seus usos |
| KR20150117259A (ko) * | 2013-01-02 | 2015-10-19 | 그렌마크 파머수티칼스 에스. 아. | Tl1a에 결합하는 항체 및 이의 용도 |
| EP2943253B1 (en) * | 2013-01-09 | 2021-10-20 | University Of Miami | Compositions and methods for the regulation of t regulatory cells using tl1a-ig fusion protein and il-2 |
| AU2014241162A1 (en) | 2013-03-27 | 2015-10-22 | Cedars-Sinai Medical Center | Mitigation and reversal of fibrosis and inflammation by inhibition of TL1A function and related signaling pathways |
| EP4105236A1 (en) | 2013-07-19 | 2022-12-21 | Cedars-Sinai Medical Center | Anti-tl1a (tnfsf15) antibody for treatment of inflammatory bowel disease |
| US20160208329A1 (en) * | 2013-09-06 | 2016-07-21 | Cedars-Sinai Medical Center | Systems, devices and methods for anti-tl1a therapy |
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| EP1919954B1 (en) | 2016-10-19 |
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| WO2007027751A3 (en) | 2007-08-09 |
| US20180078611A1 (en) | 2018-03-22 |
| US20200345809A1 (en) | 2020-11-05 |
| US20110243951A1 (en) | 2011-10-06 |
| WO2007027751A2 (en) | 2007-03-08 |
| BRPI0617057A2 (pt) | 2011-07-12 |
| US9017679B2 (en) | 2015-04-28 |
| US20070128184A1 (en) | 2007-06-07 |
| US20160015779A1 (en) | 2016-01-21 |
| US9839670B2 (en) | 2017-12-12 |
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