CA2551789C - Neutral endopeptidase (nep) and human soluble endopeptidase (hsep) inhibitors for prophylaxis and treatment of neurodegenerative disorders - Google Patents
Neutral endopeptidase (nep) and human soluble endopeptidase (hsep) inhibitors for prophylaxis and treatment of neurodegenerative disorders Download PDFInfo
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- CA2551789C CA2551789C CA2551789A CA2551789A CA2551789C CA 2551789 C CA2551789 C CA 2551789C CA 2551789 A CA2551789 A CA 2551789A CA 2551789 A CA2551789 A CA 2551789A CA 2551789 C CA2551789 C CA 2551789C
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| EP04100067.0 | 2004-01-12 | ||
| US60/535,538 | 2004-01-12 | ||
| PCT/EP2005/050075 WO2005067937A1 (en) | 2004-01-12 | 2005-01-10 | Neutral endopeptidase (nep) and human soluble endopeptidase (hsep) inhibitors for prophylaxis and treatment of neurodegenerative disorders |
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| CA2551789C true CA2551789C (en) | 2011-05-03 |
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| CA2551789A Expired - Fee Related CA2551789C (en) | 2004-01-12 | 2005-01-10 | Neutral endopeptidase (nep) and human soluble endopeptidase (hsep) inhibitors for prophylaxis and treatment of neurodegenerative disorders |
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| JP (1) | JP4951350B2 (pl) |
| KR (1) | KR101219580B1 (pl) |
| CN (1) | CN101076339B (pl) |
| AT (1) | ATE406899T1 (pl) |
| AU (1) | AU2005205067B2 (pl) |
| BR (1) | BRPI0506750A (pl) |
| CA (1) | CA2551789C (pl) |
| CY (1) | CY1108588T1 (pl) |
| DE (1) | DE602005009487D1 (pl) |
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| PL (1) | PL1706121T3 (pl) |
| PT (1) | PT1706121E (pl) |
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| SI (1) | SI1706121T1 (pl) |
| UA (1) | UA82008C2 (pl) |
| WO (1) | WO2005067937A1 (pl) |
| ZA (1) | ZA200605549B (pl) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120034193A1 (en) * | 2009-01-24 | 2012-02-09 | Daryl Rees | Treatment of neurotrophic factor mediated disorders |
| AR079059A1 (es) | 2009-12-07 | 2011-12-21 | Abbott Healthcare Products Bv | Acido ((3s)-3-(((1-(((2r)-2-carboxi-4-(1-naftil) butil) ciclopentil)-carbonil) amino )-2-oxo-2,3,4,5-tetrahidro-1h-1-benzazepin-1-il) acetico cristalino, su preparacion y uso |
| CN106065006B (zh) * | 2015-04-22 | 2020-06-05 | 深圳信立泰药业股份有限公司 | 一种中性内肽酶抑制剂盐晶型及其制备方法 |
| PL424453A1 (pl) * | 2018-01-31 | 2019-08-12 | Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością | Sposoby zmniejszania szkodliwego działania niedoboru perfuzji narządów miąższowych przez inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (hSEP) |
| PL424452A1 (pl) | 2018-01-31 | 2019-08-12 | Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością | Inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (hSEP) do profilaktyki i leczenia chorób oczu |
| CN110590695B (zh) * | 2019-10-22 | 2023-03-21 | 南华大学 | 苯并氮杂环类化合物及其应用 |
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| DE19510566A1 (de) * | 1995-03-23 | 1996-09-26 | Kali Chemie Pharma Gmbh | Benzazepin-, Benzoxazepin- und Benzothiazepin-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE19750002A1 (de) * | 1997-11-12 | 1999-05-20 | Solvay Pharm Gmbh | Phosphonsäure-substituierte Benzazepinon-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| JP4350306B2 (ja) * | 1998-04-23 | 2009-10-21 | ノバルティス アクチエンゲゼルシャフト | エンドセリン変換酵素のチオール型阻害剤 |
| US20020013307A1 (en) * | 2000-05-23 | 2002-01-31 | Pablo Lapuerta | Use of vasopeptidase inhibitors to treat or slow the progression of cognitive dysfunction and to treat and/or prevent dementia |
| US6505135B2 (en) * | 2001-03-13 | 2003-01-07 | Micro Motion, Inc. | Initialization algorithm for drive control in a coriolis flowmeter |
| AR039352A1 (es) * | 2001-05-18 | 2005-02-16 | Solvay Pharm Gmbh | Uso de un compuesto que tiene actividad inhibitoria combinada y concurrente con endopeptidasa neutra y metaloproteasa igs5. |
| CL2004000545A1 (es) * | 2003-03-18 | 2005-01-28 | Pharmacia Corp Sa Organizada B | Uso de un antagonista de los receptores de aldosterona y un antagonista de receptores de endotelina para el tratamiento o profilaxis de una condicion patologica relacionada con hipertension, disfuncion renal, insulinopatia y enfermedades cardiovascul |
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- 2005-01-10 RU RU2006129288/15A patent/RU2362563C2/ru active
- 2005-01-10 AT AT05701469T patent/ATE406899T1/de active
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Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0506750A (pt) | 2007-05-22 |
| ATE406899T1 (de) | 2008-09-15 |
| DK1706121T3 (da) | 2009-01-05 |
| CA2551789A1 (en) | 2005-07-28 |
| WO2005067937A1 (en) | 2005-07-28 |
| IL176456A (en) | 2010-03-28 |
| KR101219580B1 (ko) | 2013-01-08 |
| AU2005205067B2 (en) | 2009-10-22 |
| RU2362563C2 (ru) | 2009-07-27 |
| PT1706121E (pt) | 2008-12-04 |
| KR20060123541A (ko) | 2006-12-01 |
| DE602005009487D1 (de) | 2008-10-16 |
| JP4951350B2 (ja) | 2012-06-13 |
| NO20063623L (no) | 2006-10-12 |
| JP2007517834A (ja) | 2007-07-05 |
| PL1706121T3 (pl) | 2009-02-27 |
| CN101076339A (zh) | 2007-11-21 |
| EP1706121A1 (en) | 2006-10-04 |
| IL176456A0 (en) | 2006-10-05 |
| HRP20080611T3 (hr) | 2008-12-31 |
| UA82008C2 (uk) | 2008-02-25 |
| ES2313279T3 (es) | 2009-03-01 |
| SI1706121T1 (sl) | 2009-02-28 |
| AU2005205067A1 (en) | 2005-07-28 |
| EP1706121B1 (en) | 2008-09-03 |
| RU2006129288A (ru) | 2008-02-20 |
| CY1108588T1 (el) | 2014-04-09 |
| ZA200605549B (en) | 2007-12-27 |
| CN101076339B (zh) | 2011-02-09 |
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