PL1706121T3 - Inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (HSEP) do zapobiegania i leczenia zaburzeń neurodegeneracyjnych - Google Patents
Inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (HSEP) do zapobiegania i leczenia zaburzeń neurodegeneracyjnychInfo
- Publication number
- PL1706121T3 PL1706121T3 PL05701469T PL05701469T PL1706121T3 PL 1706121 T3 PL1706121 T3 PL 1706121T3 PL 05701469 T PL05701469 T PL 05701469T PL 05701469 T PL05701469 T PL 05701469T PL 1706121 T3 PL1706121 T3 PL 1706121T3
- Authority
- PL
- Poland
- Prior art keywords
- endopeptidase
- hsep
- nep
- prophylaxis
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53553804P | 2004-01-12 | 2004-01-12 | |
| EP04100067 | 2004-01-12 | ||
| EP05701469A EP1706121B1 (en) | 2004-01-12 | 2005-01-10 | Neutral endopeptidase (nep) and human soluble endopeptidase (hsep) inhibitors for prophylaxis and treatment of neurodegenerative disorders |
| PCT/EP2005/050075 WO2005067937A1 (en) | 2004-01-12 | 2005-01-10 | Neutral endopeptidase (nep) and human soluble endopeptidase (hsep) inhibitors for prophylaxis and treatment of neurodegenerative disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1706121T3 true PL1706121T3 (pl) | 2009-02-27 |
Family
ID=34796705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05701469T PL1706121T3 (pl) | 2004-01-12 | 2005-01-10 | Inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (HSEP) do zapobiegania i leczenia zaburzeń neurodegeneracyjnych |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1706121B1 (pl) |
| JP (1) | JP4951350B2 (pl) |
| KR (1) | KR101219580B1 (pl) |
| CN (1) | CN101076339B (pl) |
| AT (1) | ATE406899T1 (pl) |
| AU (1) | AU2005205067B2 (pl) |
| BR (1) | BRPI0506750A (pl) |
| CA (1) | CA2551789C (pl) |
| CY (1) | CY1108588T1 (pl) |
| DE (1) | DE602005009487D1 (pl) |
| DK (1) | DK1706121T3 (pl) |
| ES (1) | ES2313279T3 (pl) |
| HR (1) | HRP20080611T3 (pl) |
| IL (1) | IL176456A (pl) |
| NO (1) | NO20063623L (pl) |
| PL (1) | PL1706121T3 (pl) |
| PT (1) | PT1706121E (pl) |
| RU (1) | RU2362563C2 (pl) |
| SI (1) | SI1706121T1 (pl) |
| UA (1) | UA82008C2 (pl) |
| WO (1) | WO2005067937A1 (pl) |
| ZA (1) | ZA200605549B (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120034193A1 (en) * | 2009-01-24 | 2012-02-09 | Daryl Rees | Treatment of neurotrophic factor mediated disorders |
| AR079059A1 (es) | 2009-12-07 | 2011-12-21 | Abbott Healthcare Products Bv | Acido ((3s)-3-(((1-(((2r)-2-carboxi-4-(1-naftil) butil) ciclopentil)-carbonil) amino )-2-oxo-2,3,4,5-tetrahidro-1h-1-benzazepin-1-il) acetico cristalino, su preparacion y uso |
| CN106065006B (zh) * | 2015-04-22 | 2020-06-05 | 深圳信立泰药业股份有限公司 | 一种中性内肽酶抑制剂盐晶型及其制备方法 |
| PL424453A1 (pl) * | 2018-01-31 | 2019-08-12 | Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością | Sposoby zmniejszania szkodliwego działania niedoboru perfuzji narządów miąższowych przez inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (hSEP) |
| PL424452A1 (pl) | 2018-01-31 | 2019-08-12 | Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością | Inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (hSEP) do profilaktyki i leczenia chorób oczu |
| CN110590695B (zh) * | 2019-10-22 | 2023-03-21 | 南华大学 | 苯并氮杂环类化合物及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19510566A1 (de) * | 1995-03-23 | 1996-09-26 | Kali Chemie Pharma Gmbh | Benzazepin-, Benzoxazepin- und Benzothiazepin-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE19750002A1 (de) * | 1997-11-12 | 1999-05-20 | Solvay Pharm Gmbh | Phosphonsäure-substituierte Benzazepinon-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| JP4350306B2 (ja) * | 1998-04-23 | 2009-10-21 | ノバルティス アクチエンゲゼルシャフト | エンドセリン変換酵素のチオール型阻害剤 |
| US20020013307A1 (en) * | 2000-05-23 | 2002-01-31 | Pablo Lapuerta | Use of vasopeptidase inhibitors to treat or slow the progression of cognitive dysfunction and to treat and/or prevent dementia |
| US6505135B2 (en) * | 2001-03-13 | 2003-01-07 | Micro Motion, Inc. | Initialization algorithm for drive control in a coriolis flowmeter |
| AR039352A1 (es) * | 2001-05-18 | 2005-02-16 | Solvay Pharm Gmbh | Uso de un compuesto que tiene actividad inhibitoria combinada y concurrente con endopeptidasa neutra y metaloproteasa igs5. |
| CL2004000545A1 (es) * | 2003-03-18 | 2005-01-28 | Pharmacia Corp Sa Organizada B | Uso de un antagonista de los receptores de aldosterona y un antagonista de receptores de endotelina para el tratamiento o profilaxis de una condicion patologica relacionada con hipertension, disfuncion renal, insulinopatia y enfermedades cardiovascul |
-
2005
- 2005-01-10 PL PL05701469T patent/PL1706121T3/pl unknown
- 2005-01-10 CN CN2005800022847A patent/CN101076339B/zh not_active Expired - Fee Related
- 2005-01-10 SI SI200530457T patent/SI1706121T1/sl unknown
- 2005-01-10 WO PCT/EP2005/050075 patent/WO2005067937A1/en not_active Ceased
- 2005-01-10 RU RU2006129288/15A patent/RU2362563C2/ru active
- 2005-01-10 AT AT05701469T patent/ATE406899T1/de active
- 2005-01-10 ES ES05701469T patent/ES2313279T3/es not_active Expired - Lifetime
- 2005-01-10 AU AU2005205067A patent/AU2005205067B2/en not_active Ceased
- 2005-01-10 CA CA2551789A patent/CA2551789C/en not_active Expired - Fee Related
- 2005-01-10 EP EP05701469A patent/EP1706121B1/en not_active Expired - Lifetime
- 2005-01-10 DK DK05701469T patent/DK1706121T3/da active
- 2005-01-10 BR BRPI0506750-2A patent/BRPI0506750A/pt not_active Application Discontinuation
- 2005-01-10 HR HR20080611T patent/HRP20080611T3/xx unknown
- 2005-01-10 JP JP2006548311A patent/JP4951350B2/ja not_active Expired - Fee Related
- 2005-01-10 DE DE602005009487T patent/DE602005009487D1/de not_active Expired - Lifetime
- 2005-01-10 PT PT05701469T patent/PT1706121E/pt unknown
- 2005-10-01 UA UAA200609032A patent/UA82008C2/uk unknown
-
2006
- 2006-06-21 IL IL176456A patent/IL176456A/en active IP Right Grant
- 2006-07-05 ZA ZA200605549A patent/ZA200605549B/xx unknown
- 2006-08-10 NO NO20063623A patent/NO20063623L/no not_active Application Discontinuation
- 2006-08-11 KR KR1020067016297A patent/KR101219580B1/ko not_active Expired - Fee Related
-
2008
- 2008-11-24 CY CY20081101348T patent/CY1108588T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0506750A (pt) | 2007-05-22 |
| ATE406899T1 (de) | 2008-09-15 |
| DK1706121T3 (da) | 2009-01-05 |
| CA2551789A1 (en) | 2005-07-28 |
| WO2005067937A1 (en) | 2005-07-28 |
| IL176456A (en) | 2010-03-28 |
| KR101219580B1 (ko) | 2013-01-08 |
| AU2005205067B2 (en) | 2009-10-22 |
| RU2362563C2 (ru) | 2009-07-27 |
| PT1706121E (pt) | 2008-12-04 |
| KR20060123541A (ko) | 2006-12-01 |
| DE602005009487D1 (de) | 2008-10-16 |
| JP4951350B2 (ja) | 2012-06-13 |
| NO20063623L (no) | 2006-10-12 |
| JP2007517834A (ja) | 2007-07-05 |
| CN101076339A (zh) | 2007-11-21 |
| EP1706121A1 (en) | 2006-10-04 |
| CA2551789C (en) | 2011-05-03 |
| IL176456A0 (en) | 2006-10-05 |
| HRP20080611T3 (hr) | 2008-12-31 |
| UA82008C2 (uk) | 2008-02-25 |
| ES2313279T3 (es) | 2009-03-01 |
| SI1706121T1 (sl) | 2009-02-28 |
| AU2005205067A1 (en) | 2005-07-28 |
| EP1706121B1 (en) | 2008-09-03 |
| RU2006129288A (ru) | 2008-02-20 |
| CY1108588T1 (el) | 2014-04-09 |
| ZA200605549B (en) | 2007-12-27 |
| CN101076339B (zh) | 2011-02-09 |
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