CA2491613C - An hydroxytyrosol-rich composition from olive vegetation water and method of use thereof - Google Patents

An hydroxytyrosol-rich composition from olive vegetation water and method of use thereof Download PDF

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Publication number
CA2491613C
CA2491613C CA2491613A CA2491613A CA2491613C CA 2491613 C CA2491613 C CA 2491613C CA 2491613 A CA2491613 A CA 2491613A CA 2491613 A CA2491613 A CA 2491613A CA 2491613 C CA2491613 C CA 2491613C
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CA
Canada
Prior art keywords
hydroxytyrosol
vegetation water
oleuropein
incubating
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2491613A
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English (en)
French (fr)
Other versions
CA2491613A1 (en
Inventor
Roberto Crea
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Creagri Inc
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Creagri Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Creagri Inc filed Critical Creagri Inc
Publication of CA2491613A1 publication Critical patent/CA2491613A1/en
Application granted granted Critical
Publication of CA2491613C publication Critical patent/CA2491613C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/004Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by obtaining phenols from plant material or from animal material
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/08Oxygen or sulfur directly attached to an aromatic ring system
    • A01N31/16Oxygen or sulfur directly attached to an aromatic ring system with two or more oxygen or sulfur atoms directly attached to the same aromatic ring system
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/18Antioxidants, e.g. antiradicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Agronomy & Crop Science (AREA)
  • Biotechnology (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Emergency Medicine (AREA)
  • Pest Control & Pesticides (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2491613A 2002-07-05 2003-07-03 An hydroxytyrosol-rich composition from olive vegetation water and method of use thereof Expired - Fee Related CA2491613C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/190,043 2002-07-05
US10/190,043 US7713569B2 (en) 2000-09-01 2002-07-05 Hydroxytyrosol-rich composition from olive vegetation water and method of use thereof
PCT/US2003/021111 WO2004005228A1 (en) 2002-07-05 2003-07-03 An hydroxytyrosol-rich composition from olive vegetation water and method of use thereof

Publications (2)

Publication Number Publication Date
CA2491613A1 CA2491613A1 (en) 2004-01-15
CA2491613C true CA2491613C (en) 2012-12-18

Family

ID=30114043

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2491613A Expired - Fee Related CA2491613C (en) 2002-07-05 2003-07-03 An hydroxytyrosol-rich composition from olive vegetation water and method of use thereof

Country Status (9)

Country Link
US (2) US7713569B2 (https=)
EP (1) EP1523465B1 (https=)
JP (1) JP2005532398A (https=)
KR (1) KR20050025588A (https=)
CN (1) CN1665764B (https=)
AU (1) AU2003249719B2 (https=)
CA (1) CA2491613C (https=)
ES (1) ES2873449T3 (https=)
WO (1) WO2004005228A1 (https=)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9072753B1 (en) * 2000-04-03 2015-07-07 Amy C. Brown Gargle method to reduce the duration of common cold symptoms
JP3820218B2 (ja) * 2000-09-01 2006-09-13 クレアグリ, インコーポレイテッド 植物水からヒドロキシチロソール富化組成物を得る方法
US7713569B2 (en) 2000-09-01 2010-05-11 Creagri, Inc. Hydroxytyrosol-rich composition from olive vegetation water and method of use thereof
CA2474798C (en) * 2002-02-13 2012-12-04 Creagri, Inc. Method and composition for treatment of inflammation and aids-associated neurological disorders
US7468355B2 (en) * 2002-05-22 2008-12-23 H2Rc Corporation Methods for inhibiting cancer and scar formation
ITMI20041627A1 (it) 2004-08-06 2004-11-06 Lachifarma S R L Lab Chimi Co Processo per il recupero di tirosolo idrossitirosolo e altri componenti fenolici da acque di vegetazione e metodo di ossidazione catalitica di tirosolo a idrossitirosolo
US20200319198A1 (en) * 2004-08-09 2020-10-08 Kathleen Matt Olive compositions and methods for treating inflammatory conditions
WO2006020588A1 (en) * 2004-08-09 2006-02-23 Creagri, Inc. Olive compositions and methods for treating inflammatory conditions
JP4832445B2 (ja) * 2004-11-16 2011-12-07 ディーエスエム アイピー アセッツ ビー.ブイ. 筋回復のための抗酸化化合物の使用
US9789149B2 (en) * 2005-07-19 2017-10-17 Creagri, Inc. Vegetation water composition for treatment of inflammatory skin conditions
PT103326A (pt) * 2005-07-27 2007-01-31 Inst De Biolog Ex E Tecnologic Método para obtenção de um concentrado natural rico em hidroxitirosol a partir de resíduos da produção de azeite utilizando tecnologias limpas
EP2040696B1 (en) * 2006-07-14 2017-01-25 DSM IP Assets B.V. Compositions and use thereof for the treatment, co-treatment or prevention of inflammatory disorders
EP2068901B1 (en) * 2006-10-05 2018-11-21 DSM IP Assets B.V. Use of hydroxytyrosol to reduce the amount of lactic acid in plasma
JP5175481B2 (ja) * 2006-10-23 2013-04-03 エーザイフード・ケミカル株式会社 軟骨再生促進剤
EP1938698A1 (en) * 2006-12-06 2008-07-02 DSMIP Assets B.V. Novel powders based on vegetation water from olive oil production
EP2049458B1 (en) 2007-01-26 2013-12-25 Probelte Pharma, S.A. Process for the production of hydroxytyrosol containing extract from olives and solids containing residues of olive oil extraction
US8968811B2 (en) 2007-01-26 2015-03-03 Probelte Pharma, S.A. Hydroxytrosol containing extract obtained from olives and solids containing residues of olive oil extraction
EP1982707A1 (en) * 2007-04-18 2008-10-22 DSMIP Assets B.V. Use of hydroxytyrosol as anti-aging agent
EP1982603A1 (en) * 2007-04-18 2008-10-22 DSMIP Assets B.V. Novel use of hydroxytyrosol and olive extracts/concentrates containing it
KR20100015595A (ko) * 2007-04-18 2010-02-12 디에스엠 아이피 어셋츠 비.브이. 하이드록시타이로솔 및 이를 함유하는 올리브 추출물/농축물의 신규한 용도
ES2311401B1 (es) * 2007-05-22 2009-12-22 Ges-Biolives, S.L. Procedimiento para la obtencion de extractos con alto contenido en hidroxitirosol a partir de productos derivados de la oliva.
KR20100051663A (ko) 2007-08-21 2010-05-17 디에스엠 아이피 어셋츠 비.브이. 고체 함량이 감소된 올리브 쥬스 추출물의 제조 방법
US20110111087A1 (en) * 2007-08-29 2011-05-12 Roberto Crea Food and beverage supplement
JP2009227616A (ja) * 2008-03-24 2009-10-08 Toin Gakuen オレウロペイン及び/又はヒドロキシチロソールを有効成分として含有する骨形成促進剤
US20110111086A1 (en) * 2009-11-11 2011-05-12 Lusk Lance T Method of Improving Flavor Stability In Fermented Beverages
NZ600912A (en) * 2009-12-01 2014-05-30 Seprox Biotech S L Topical use of hydroxytyrosol and derivatives for the prevention of hiv infection
US8465939B2 (en) * 2010-03-02 2013-06-18 Nox Technologies, Inc. Aging-related circulating particle-associated lipoprotein B oxidase (apoBNOX) and inhibitors thereof
IT1400373B1 (it) * 2010-06-03 2013-05-31 Mazzotta Preparazione di un estratto ricco di polifenoli e di una frazione solida da acque di vegetazione delle olive e suo uso farmaceutico, cosmetico e alimentare.
MY175348A (en) 2011-02-11 2020-06-22 Crea Roberto Treatment of elaeis fruit products with antioxidants
ITMI20110941A1 (it) 2011-05-25 2012-11-26 Phenofarm S R L Processo di produzione di un fito-estratto da acque di vegetazione esanse olearie
DE102013203753A1 (de) * 2013-03-05 2014-09-11 Wacker Chemie Ag Verfahren zur Herstellung von Hydroxytyrosol
FR3018686B1 (fr) 2014-03-24 2017-05-19 Pierre Fabre Dermo Cosmetique Utilisation cosmetique d'un extrait de margines d'olivier pour redensifier le cheveu
US10532022B2 (en) * 2014-07-21 2020-01-14 The United States Of America, As Represented By The Secretary Of Agriculture Whole stablized olive mill process water, production thereof and uses thereof
CN106610409A (zh) * 2015-10-23 2017-05-03 杭州师范大学 一种壳聚糖填充微型基质固相分散方法
JP6381076B2 (ja) 2015-12-01 2018-08-29 小豆島ヘルシーランド株式会社 紫外線遮断剤および化粧料
CN105997703B (zh) * 2016-07-05 2019-11-12 上海相宜本草化妆品股份有限公司 橄榄叶提取物以及包含该提取物的化妆品
JP7079551B2 (ja) 2016-10-04 2022-06-02 ニュートラマックス ラボラトリーズ,インコーポレイテッド ヒドロキシチロソールおよびボスウェリン酸を有する組成物
CN108314607A (zh) * 2018-05-08 2018-07-24 广西大学 一种高纯度固体羟基酪醇的纯化方法
DE102021111719A1 (de) * 2021-05-05 2022-11-10 Henkel Ag & Co. Kgaa Erhalt der Haarstruktur gegenüber Umwelteinflüssen umfassend ein Phenol und multivalente Ionen
CN113277931A (zh) * 2021-06-04 2021-08-20 陕西富恒生物科技有限公司 一种从油橄榄果中提取羟基酪醇的方法
CN116253605B (zh) * 2022-12-30 2025-09-26 山东农业大学 一种橄榄果渣多酚提取物-羟基酪醇作为生物源氮肥增效剂的应用
MA61008A1 (fr) * 2023-06-12 2024-12-31 Hind Mikdame Valorisation des marjines dans la fabrication des savons solides,mous et liquides et des produits cosmetiques.
WO2025145263A1 (es) * 2024-01-04 2025-07-10 Quimica Mavar S.A. Composición extracto polifenólico y acuoso derivado de alpechin como bioestimulante y agente protectivo para plantas
US20250275535A1 (en) * 2024-03-01 2025-09-04 Veos Pharmaceuticals, S.L. Olive tree biomass extract

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370274A (en) 1980-12-23 1983-01-25 Fps Development Partnership Olive oil recovery
US4452744A (en) 1980-12-23 1984-06-05 Fps Development Partnership Olive oil recovery
US4522119A (en) 1980-12-23 1985-06-11 Fps Development Partnership Olive oil recovery
DE3720408A1 (de) 1987-06-19 1988-12-29 Peter Dr Hussmann Verfahren und vorrichtung zur umweltschonenden beseitigung des bei der olivenpressung anfallenden abwassers
ES2006904A6 (es) 1988-04-15 1989-05-16 Jimenez Rodriguez Jose Luis Procedimiento de obtencion de aceite a partir del orujo.
AU670742B2 (en) 1991-03-21 1996-08-01 Parfums Christian Dior Novel derivative of caffeic acid, oraposide, cosmetic or pharmaceutical, particularly dermatological, composition containing it
IT1262967B (it) 1992-07-31 1996-07-23 Inn Tec Srl Macchina e procedimento per la produzione di olio di oliva senza frangitura dei noccioli.
JPH07223940A (ja) * 1994-02-14 1995-08-22 Pola Chem Ind Inc 活性酸素消去剤及びこれを含有する組成物
JP3499616B2 (ja) 1994-10-20 2004-02-23 一丸ファルコス株式会社 ヒドロキシチロソール、メラニン生成抑制剤又は過酸化脂質生成抑制剤への応用
WO1996014064A1 (en) * 1994-11-07 1996-05-17 Strecker, Robert, B. Method and composition for antiviral therapy
IT1278025B1 (it) 1995-02-21 1997-11-17 Tecnologie 2000 S R L Separatore centrifugo orizzontale, in particolare per la pruduzione di olio, con estrazione accelerata della fase liquida.
IT1276576B1 (it) 1995-05-10 1997-11-03 Tecnologie 2000 S R L Snocciolatore a lame per la preparazione di pasta di olive e apparato mobile per la produzione non industriale di olio.
WO1997021434A1 (en) 1995-12-11 1997-06-19 Inholtra, Inc. Dietary regimen of nutritional supplements for relief of symptoms of arthritis
WO1997028089A1 (en) 1996-01-31 1997-08-07 Dianellos Georgoudis Method of extraction of olive paste from vegetable water and its use as a foodstuff
EP0811678A1 (fr) 1996-06-08 1997-12-10 Societe Des Produits Nestle S.A. Extraction d'antioxydants
US5998641A (en) * 1997-01-31 1999-12-07 Unilever Patent Holdings Debittering of olive oil
US5714150A (en) 1997-01-08 1998-02-03 Nachman; Leslie Method for producing extract of olive leaves
HUP0101529A3 (en) 1998-04-14 2002-08-28 Unilever Nv Fortification of a vegetable fat with antioxidants
US6165475A (en) * 1998-07-23 2000-12-26 Creagri, Inc. Water-soluble extract from olives
US6936287B1 (en) * 1998-07-23 2005-08-30 Creagri, Inc. Water-soluble extract from olives
WO2000004794A1 (en) * 1998-07-23 2000-02-03 Creagri, Inc. Water-soluble extract from olives
EP1139797A2 (en) * 1998-12-22 2001-10-10 Unilever N.V. Food compositions fortified with anti-oxidants
US6220267B1 (en) * 1999-01-27 2001-04-24 Ceramatec, Inc. Apparatus and method for controllably delivering fluid to a second fluid stream
US6242491B1 (en) * 1999-06-25 2001-06-05 Rima Kaddurah-Daouk Use of creatine or creatine compounds for skin preservation
JP4025546B2 (ja) * 1999-10-14 2007-12-19 日清オイリオグループ株式会社 美肌剤、皮膚の抗老化剤、美白剤および皮膚外用剤
US6358542B2 (en) * 1999-12-20 2002-03-19 Usana, Inc. Antioxidant compositions extracted from olives and olive by-products
US6437004B1 (en) 2000-04-06 2002-08-20 Nicholas V. Perricone Treatment of skin damage using olive oil polyphenols
US6440465B1 (en) * 2000-05-01 2002-08-27 Bioderm, Inc. Topical composition for the treatment of psoriasis and related skin disorders
JP3820218B2 (ja) * 2000-09-01 2006-09-13 クレアグリ, インコーポレイテッド 植物水からヒドロキシチロソール富化組成物を得る方法
US7713569B2 (en) 2000-09-01 2010-05-11 Creagri, Inc. Hydroxytyrosol-rich composition from olive vegetation water and method of use thereof
PT1369407E (pt) * 2001-02-15 2009-01-22 Consejo Superior Investigacion Processo de obtenção de hidroxitirosol purificado a partir de produtos e subprodutos derivados da oliveira
JP4587200B2 (ja) * 2001-10-09 2010-11-24 株式会社ファンケル グルタチオン増強用組成物
US6906100B2 (en) * 2002-02-08 2005-06-14 Lavipharm S.A. Compounds and compositions derived from olives and methods of the use thereof
CA2474798C (en) * 2002-02-13 2012-12-04 Creagri, Inc. Method and composition for treatment of inflammation and aids-associated neurological disorders
US20050103711A1 (en) * 2003-11-18 2005-05-19 Wayne Emmons Isolation of oleuropein aglycon from olive vegetation water
US9789149B2 (en) * 2005-07-19 2017-10-17 Creagri, Inc. Vegetation water composition for treatment of inflammatory skin conditions

Also Published As

Publication number Publication date
US7713569B2 (en) 2010-05-11
EP1523465B1 (en) 2021-03-03
WO2004005228A1 (en) 2004-01-15
EP1523465A1 (en) 2005-04-20
CA2491613A1 (en) 2004-01-15
AU2003249719A1 (en) 2004-01-23
US20100216874A1 (en) 2010-08-26
AU2003249719B2 (en) 2010-03-04
JP2005532398A (ja) 2005-10-27
KR20050025588A (ko) 2005-03-14
CN1665764A (zh) 2005-09-07
HK1084935A1 (en) 2006-08-11
CN1665764B (zh) 2011-05-25
US20030108651A1 (en) 2003-06-12
ES2873449T3 (es) 2021-11-03

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