CA2321165A1 - Antibodies against human cd40 - Google Patents

Antibodies against human cd40 Download PDF

Info

Publication number
CA2321165A1
CA2321165A1 CA002321165A CA2321165A CA2321165A1 CA 2321165 A1 CA2321165 A1 CA 2321165A1 CA 002321165 A CA002321165 A CA 002321165A CA 2321165 A CA2321165 A CA 2321165A CA 2321165 A1 CA2321165 A1 CA 2321165A1
Authority
CA
Canada
Prior art keywords
antibody
variable region
human
chain variable
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002321165A
Other languages
English (en)
French (fr)
Inventor
Alejandro A. Aruffo
Diane Hollenbaugh
Anthony W. Siadak
Karen K. Berry
Barbara A. Thorne
Jurgen Bajorath
Herren Wu
William D. Huse
Jeffry D. Watkins
Linda J. Harris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2321165A1 publication Critical patent/CA2321165A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002321165A 1998-02-19 1999-02-10 Antibodies against human cd40 Abandoned CA2321165A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/026,291 US6051228A (en) 1998-02-19 1998-02-19 Antibodies against human CD40
US09/026,291 1998-02-19
PCT/US1999/002949 WO1999042075A2 (en) 1998-02-19 1999-02-10 Antibodies against human cd40

Publications (1)

Publication Number Publication Date
CA2321165A1 true CA2321165A1 (en) 1999-08-26

Family

ID=21830976

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002321165A Abandoned CA2321165A1 (en) 1998-02-19 1999-02-10 Antibodies against human cd40

Country Status (31)

Country Link
US (3) US6051228A (enExample)
EP (1) EP1054692A4 (enExample)
JP (1) JP2002503495A (enExample)
KR (1) KR100564376B1 (enExample)
CN (1) CN1198647C (enExample)
AR (1) AR018101A1 (enExample)
AU (1) AU751064B2 (enExample)
BG (1) BG65010B1 (enExample)
BR (1) BR9908045A (enExample)
CA (1) CA2321165A1 (enExample)
CO (1) CO4830493A1 (enExample)
CZ (1) CZ20003008A3 (enExample)
EE (1) EE200000470A (enExample)
GE (1) GEP20033016B (enExample)
HU (1) HUP0100763A3 (enExample)
ID (1) ID25792A (enExample)
IL (2) IL137294A0 (enExample)
LT (1) LT4837B (enExample)
LV (1) LV12561B (enExample)
MY (1) MY121464A (enExample)
NO (1) NO20004133L (enExample)
NZ (1) NZ505696A (enExample)
PE (1) PE20000268A1 (enExample)
PL (1) PL197143B1 (enExample)
RU (1) RU2220980C2 (enExample)
SK (1) SK12092000A3 (enExample)
TR (1) TR200002405T2 (enExample)
TW (1) TWI226334B (enExample)
UA (1) UA71909C2 (enExample)
WO (1) WO1999042075A2 (enExample)
ZA (1) ZA991307B (enExample)

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* Cited by examiner, † Cited by third party
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