CN1198647C - 抗人cd40抗体 - Google Patents

抗人cd40抗体 Download PDF

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Publication number
CN1198647C
CN1198647C CNB998031496A CN99803149A CN1198647C CN 1198647 C CN1198647 C CN 1198647C CN B998031496 A CNB998031496 A CN B998031496A CN 99803149 A CN99803149 A CN 99803149A CN 1198647 C CN1198647 C CN 1198647C
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CN
China
Prior art keywords
antibody
human
antibodies
cells
monkeys
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Expired - Fee Related
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CNB998031496A
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English (en)
Chinese (zh)
Other versions
CN1307484A (zh
Inventor
A·A·阿鲁富
D·霍伦鲍格
A·W·西尔达克
K·K·贝里
L·J·哈里斯
B·A·托尔尼
J·巴约拉斯
H·吴
W·D·胡赛
J·D·瓦特金斯
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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Publication of CN1307484A publication Critical patent/CN1307484A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CNB998031496A 1998-02-19 1999-02-10 抗人cd40抗体 Expired - Fee Related CN1198647C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/026,291 US6051228A (en) 1998-02-19 1998-02-19 Antibodies against human CD40
US09/026,291 1998-02-19

Publications (2)

Publication Number Publication Date
CN1307484A CN1307484A (zh) 2001-08-08
CN1198647C true CN1198647C (zh) 2005-04-27

Family

ID=21830976

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998031496A Expired - Fee Related CN1198647C (zh) 1998-02-19 1999-02-10 抗人cd40抗体

Country Status (31)

Country Link
US (3) US6051228A (enExample)
EP (1) EP1054692A4 (enExample)
JP (1) JP2002503495A (enExample)
KR (1) KR100564376B1 (enExample)
CN (1) CN1198647C (enExample)
AR (1) AR018101A1 (enExample)
AU (1) AU751064B2 (enExample)
BG (1) BG65010B1 (enExample)
BR (1) BR9908045A (enExample)
CA (1) CA2321165A1 (enExample)
CO (1) CO4830493A1 (enExample)
CZ (1) CZ20003008A3 (enExample)
EE (1) EE200000470A (enExample)
GE (1) GEP20033016B (enExample)
HU (1) HUP0100763A3 (enExample)
ID (1) ID25792A (enExample)
IL (2) IL137294A0 (enExample)
LT (1) LT4837B (enExample)
LV (1) LV12561B (enExample)
MY (1) MY121464A (enExample)
NO (1) NO20004133L (enExample)
NZ (1) NZ505696A (enExample)
PE (1) PE20000268A1 (enExample)
PL (1) PL197143B1 (enExample)
RU (1) RU2220980C2 (enExample)
SK (1) SK12092000A3 (enExample)
TR (1) TR200002405T2 (enExample)
TW (1) TWI226334B (enExample)
UA (1) UA71909C2 (enExample)
WO (1) WO1999042075A2 (enExample)
ZA (1) ZA991307B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105884903A (zh) * 2009-03-10 2016-08-24 贝勒研究院 靶向抗原呈递细胞的疫苗

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* Cited by examiner, † Cited by third party
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