CA2267070A1 - Compositions and methods for immobilizing nucleic acids to solid supports - Google Patents

Compositions and methods for immobilizing nucleic acids to solid supports Download PDF

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Publication number
CA2267070A1
CA2267070A1 CA002267070A CA2267070A CA2267070A1 CA 2267070 A1 CA2267070 A1 CA 2267070A1 CA 002267070 A CA002267070 A CA 002267070A CA 2267070 A CA2267070 A CA 2267070A CA 2267070 A1 CA2267070 A1 CA 2267070A1
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CA
Canada
Prior art keywords
bead
beads
macromolecule
conjugated
solid support
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002267070A
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English (en)
French (fr)
Inventor
David M. Lough
Hubert Koster
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sequenom Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27505632&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2267070(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/746,036 external-priority patent/US5900481A/en
Priority claimed from US08/787,639 external-priority patent/US6024925A/en
Priority claimed from US08/786,988 external-priority patent/US7285422B1/en
Priority claimed from US08/933,792 external-priority patent/US6133436A/en
Application filed by Individual filed Critical Individual
Publication of CA2267070A1 publication Critical patent/CA2267070A1/en
Abandoned legal-status Critical Current

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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0244—Drop counters; Drop formers using pins
    • B01L3/0255—Drop counters; Drop formers using pins characterized by the form or material of the pin tip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2408—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of hydroxyalkyl compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices
    • G01N35/1067—Multiple transfer devices for transfer to or from containers having different spacing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices
    • G01N35/1074—Multiple transfer devices arranged in a two-dimensional array

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  • Apparatus Associated With Microorganisms And Enzymes (AREA)
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CA002267070A 1996-11-06 1997-11-06 Compositions and methods for immobilizing nucleic acids to solid supports Abandoned CA2267070A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US08/746,036 US5900481A (en) 1996-11-06 1996-11-06 Bead linkers for immobilizing nucleic acids to solid supports
US08/746,036 1996-11-06
US08/786,988 1997-01-23
US08/787,639 1997-01-23
US08/787,639 US6024925A (en) 1997-01-23 1997-01-23 Systems and methods for preparing low volume analyte array elements
US08/786,988 US7285422B1 (en) 1997-01-23 1997-01-23 Systems and methods for preparing and analyzing low volume analyte array elements
US08/933,792 US6133436A (en) 1996-11-06 1997-09-19 Beads bound to a solid support and to nucleic acids
US08/933,792 1997-09-19
PCT/US1997/020194 WO1998020019A1 (en) 1996-11-06 1997-11-06 Compositions and methods for immobilizing nucleic acids to solid supports

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DE69706187D1 (de) 2001-09-20
EP0937097B1 (en) 2001-08-16
AU746737B2 (en) 2002-05-02
ATE204290T1 (de) 2001-09-15
DE19782097T1 (de) 1999-10-14
WO1998020019A1 (en) 1998-05-14
HK1020197A1 (en) 2000-03-31
JP2001501967A (ja) 2001-02-13
NO992167L (no) 1999-07-05
AU5247298A (en) 1998-05-29
JP4963139B2 (ja) 2012-06-27
NO992167D0 (no) 1999-05-04
EP0937097A1 (en) 1999-08-25
DE69706187T2 (de) 2002-04-11

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