SI1458888T1 - Metode zdravljenja psihoze in shizofrenije na osnovi polimorfizmov gena cntf - Google Patents

Metode zdravljenja psihoze in shizofrenije na osnovi polimorfizmov gena cntf

Info

Publication number
SI1458888T1
SI1458888T1 SI200230940T SI200230940T SI1458888T1 SI 1458888 T1 SI1458888 T1 SI 1458888T1 SI 200230940 T SI200230940 T SI 200230940T SI 200230940 T SI200230940 T SI 200230940T SI 1458888 T1 SI1458888 T1 SI 1458888T1
Authority
SI
Slovenia
Prior art keywords
polymorphisms
methods
cntf gene
treating psychosis
schizophrenia based
Prior art date
Application number
SI200230940T
Other languages
English (en)
Inventor
Sridhar Kudaravalli
Mihael Hristos Polymeropoulos
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SI1458888T1 publication Critical patent/SI1458888T1/sl

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/30—Psychoses; Psychiatry
    • G01N2800/302—Schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Psychiatry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI200230940T 2001-12-10 2002-12-09 Metode zdravljenja psihoze in shizofrenije na osnovi polimorfizmov gena cntf SI1458888T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33983501P 2001-12-10 2001-12-10
PCT/EP2002/013937 WO2003054226A2 (en) 2001-12-10 2002-12-09 Methods of treating psychosis and schizophrenia based on a polymorphism in the ctf gene
EP02791794A EP1458888B1 (en) 2001-12-10 2002-12-09 Methods of treating psychosis and schizophrenia based on polymorphisms in the cntf gene

Publications (1)

Publication Number Publication Date
SI1458888T1 true SI1458888T1 (sl) 2011-07-29

Family

ID=23330814

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200230940T SI1458888T1 (sl) 2001-12-10 2002-12-09 Metode zdravljenja psihoze in shizofrenije na osnovi polimorfizmov gena cntf

Country Status (16)

Country Link
US (3) US20050059006A1 (sl)
EP (1) EP1458888B1 (sl)
JP (2) JP2005512576A (sl)
CN (1) CN1612941B (sl)
AT (1) ATE503845T1 (sl)
AU (1) AU2002358110A1 (sl)
BR (1) BRPI0214821B8 (sl)
CA (1) CA2468972A1 (sl)
CY (1) CY1111594T1 (sl)
DE (1) DE60239634D1 (sl)
DK (1) DK1458888T3 (sl)
ES (1) ES2364037T3 (sl)
HK (1) HK1069413A1 (sl)
PT (1) PT1458888E (sl)
SI (1) SI1458888T1 (sl)
WO (1) WO2003054226A2 (sl)

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EP2152917B1 (en) 2007-05-18 2016-03-23 Vanda Pharmaceuticals Inc. Genetic markers for efficacy of iloperidone in the treatment of psychotic symptoms
EP2198049A1 (en) * 2007-09-10 2010-06-23 Vanda Pharmaceuticals Inc. Antipsychotic treatment based on snp genotype
JP5653753B2 (ja) * 2007-09-10 2015-01-14 ヴァンダ ファーマシューティカルズ インコーポレイテッド Ｓｎｐ遺伝子型に基づくｑｔ延長の予測
ES2527515T3 (es) 2007-12-13 2015-01-26 Vanda Pharmaceuticals Inc. Método y composición para tratar una afección mediada por un adrenoceptor alfa
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EP2570501A3 (en) * 2008-01-02 2013-04-10 Suregene Llc Genetic markers of mental illness
EP2581453A3 (en) * 2008-01-17 2013-07-10 Suregene Llc Genetic Markers of Mental Illness
JP2012507297A (ja) * 2008-10-29 2012-03-29 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Ｅｒｂｂ４遺伝子の多型に基づく精神病及び統合失調症の治療法
EP2430183B1 (en) 2009-05-15 2014-12-17 Vanda Pharmaceuticals Inc. Antipsychotic treatment based on drd2 or ankk1 snp genotype
ES2677474T3 (es) 2012-03-14 2018-08-02 Vanda Pharmaceuticals Inc. Un metabolito de iloperidona para uso en el tratamiento de trastornos psiquiátricos
US10877498B2 (en) * 2017-10-27 2020-12-29 Brasscraft Manufacturing Company Excess flow and thermal valve
EP3844758A1 (en) * 2018-08-28 2021-07-07 Koninklijke Philips N.V. Method for assessing genome alignment basis
US11214827B2 (en) * 2018-08-30 2022-01-04 Vanda Pharmaceuticals Inc. Genetic markers for enhancing efficacy of antipsychotic treatment with iloperidone
US20220290237A1 (en) * 2019-04-24 2022-09-15 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for predicting the response of antipsychotic drugs
CN110184345B (zh) * 2019-07-11 2020-05-05 南京先声医学检验有限公司 用于检测精神及神经类疾病用药相关snp位点的引物组、应用、产品及方法
CN111187829A (zh) * 2020-02-24 2020-05-22 内蒙古医科大学 Lp基因启动子区甲基化检测引物与检测方法及其应用

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Also Published As

Publication number Publication date
EP1458888A2 (en) 2004-09-22
US20050059006A1 (en) 2005-03-17
HK1069413A1 (en) 2005-05-20
CN1612941B (zh) 2011-11-16
JP2005512576A (ja) 2005-05-12
PT1458888E (pt) 2011-06-01
BR0214821A (pt) 2004-11-03
EP1458888B1 (en) 2011-03-30
CA2468972A1 (en) 2003-07-03
WO2003054226A2 (en) 2003-07-03
JP2011006422A (ja) 2011-01-13
BRPI0214821B8 (pt) 2021-07-27
US20080027106A1 (en) 2008-01-31
AU2002358110A8 (en) 2003-07-09
CY1111594T1 (el) 2015-10-07
ATE503845T1 (de) 2011-04-15
DE60239634D1 (de) 2011-05-12
AU2002358110A1 (en) 2003-07-09
DK1458888T3 (da) 2011-06-20
ES2364037T3 (es) 2011-08-23
BRPI0214821B1 (pt) 2015-07-07
JP5785697B2 (ja) 2015-09-30
WO2003054226A3 (en) 2004-04-01
CN1612941A (zh) 2005-05-04
US20090239908A1 (en) 2009-09-24
US8460867B2 (en) 2013-06-11

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