ZA200205484B - New therapeutic combinations of (S)-2-(benzylaminomethyl)-2,3,8,9,-tetrahydro-7H-1,4-dioxino[2,3-e]indol-8-one and neuroleptics for the treatment or prevention of psychotic disorders. - Google Patents

New therapeutic combinations of (S)-2-(benzylaminomethyl)-2,3,8,9,-tetrahydro-7H-1,4-dioxino[2,3-e]indol-8-one and neuroleptics for the treatment or prevention of psychotic disorders.

Info

Publication number
ZA200205484B
ZA200205484B ZA200205484A ZA200205484A ZA200205484B ZA 200205484 B ZA200205484 B ZA 200205484B ZA 200205484 A ZA200205484 A ZA 200205484A ZA 200205484 A ZA200205484 A ZA 200205484A ZA 200205484 B ZA200205484 B ZA 200205484B
Authority
ZA
South Africa
Prior art keywords
benzylaminomethyl
dioxino
neuroleptics
indol
tetrahydro
Prior art date
Application number
ZA200205484A
Inventor
Karen Lovell Marquis
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of ZA200205484B publication Critical patent/ZA200205484B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
ZA200205484A 1999-12-10 2002-07-09 New therapeutic combinations of (S)-2-(benzylaminomethyl)-2,3,8,9,-tetrahydro-7H-1,4-dioxino[2,3-e]indol-8-one and neuroleptics for the treatment or prevention of psychotic disorders. ZA200205484B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45860799A 1999-12-10 1999-12-10

Publications (1)

Publication Number Publication Date
ZA200205484B true ZA200205484B (en) 2003-12-31

Family

ID=23821437

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200205484A ZA200205484B (en) 1999-12-10 2002-07-09 New therapeutic combinations of (S)-2-(benzylaminomethyl)-2,3,8,9,-tetrahydro-7H-1,4-dioxino[2,3-e]indol-8-one and neuroleptics for the treatment or prevention of psychotic disorders.

Country Status (20)

Country Link
EP (1) EP1235570A2 (en)
JP (1) JP5557409B2 (en)
KR (1) KR100772854B1 (en)
CN (1) CN1230164C (en)
AR (1) AR026756A1 (en)
AU (1) AU784211B2 (en)
BR (1) BR0016168A (en)
CA (1) CA2396351C (en)
CZ (1) CZ20021880A3 (en)
EA (1) EA005002B1 (en)
HK (1) HK1045942A1 (en)
HU (1) HUP0203309A3 (en)
IL (2) IL149669A0 (en)
MX (1) MXPA02005649A (en)
NO (1) NO20022739L (en)
NZ (1) NZ519381A (en)
PL (1) PL355292A1 (en)
TW (1) TWI222864B (en)
WO (1) WO2001041750A2 (en)
ZA (1) ZA200205484B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5547865B2 (en) 2003-10-29 2014-07-16 ワイス・エルエルシー Sustained release pharmaceutical composition comprising aprindole and its derivatives
EP1856126A2 (en) 2005-02-17 2007-11-21 Wyeth a Corporation of the State of Delaware Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
MX2010008875A (en) * 2008-02-13 2010-08-31 Targacept Inc Combination of alpha 7 nicotinic agonists and antipsychotics.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2987484B2 (en) * 1995-03-16 1999-12-06 大塚製薬 株式会社 Method for producing carbostyril derivative
US5756532A (en) * 1995-11-06 1998-05-26 American Home Products Corporation Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
GB9627005D0 (en) * 1996-12-27 1997-02-12 Knoll Ag Therapeutic agents

Also Published As

Publication number Publication date
TWI222864B (en) 2004-11-01
JP5557409B2 (en) 2014-07-23
PL355292A1 (en) 2004-04-05
KR20030016207A (en) 2003-02-26
NO20022739D0 (en) 2002-06-07
CN1230164C (en) 2005-12-07
EA200200656A1 (en) 2002-12-26
CA2396351A1 (en) 2001-06-14
HUP0203309A2 (en) 2003-01-28
AR026756A1 (en) 2003-02-26
WO2001041750A3 (en) 2002-02-14
MXPA02005649A (en) 2004-09-10
AU784211B2 (en) 2006-02-23
CA2396351C (en) 2009-11-10
BR0016168A (en) 2002-08-20
EA005002B1 (en) 2004-10-28
HK1045942A1 (en) 2002-12-20
IL149669A (en) 2006-06-11
JP2003516350A (en) 2003-05-13
NO20022739L (en) 2002-06-07
AU1949001A (en) 2001-06-18
WO2001041750A2 (en) 2001-06-14
KR100772854B1 (en) 2007-11-02
NZ519381A (en) 2004-04-30
EP1235570A2 (en) 2002-09-04
IL149669A0 (en) 2002-11-10
HUP0203309A3 (en) 2004-12-28
CN1409633A (en) 2003-04-09
CZ20021880A3 (en) 2002-08-14

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ZA200205484B (en) New therapeutic combinations of (S)-2-(benzylaminomethyl)-2,3,8,9,-tetrahydro-7H-1,4-dioxino[2,3-e]indol-8-one and neuroleptics for the treatment or prevention of psychotic disorders.