CA2223027A1 - Electrochemiluminescent enzyme immunoassay - Google Patents

Electrochemiluminescent enzyme immunoassay Download PDF

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Publication number
CA2223027A1
CA2223027A1 CA002223027A CA2223027A CA2223027A1 CA 2223027 A1 CA2223027 A1 CA 2223027A1 CA 002223027 A CA002223027 A CA 002223027A CA 2223027 A CA2223027 A CA 2223027A CA 2223027 A1 CA2223027 A1 CA 2223027A1
Authority
CA
Canada
Prior art keywords
ecl
enzyme
analyte
detectant
substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002223027A
Other languages
English (en)
French (fr)
Inventor
Mark T. Martin
Richard Saul
Pam Liang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioveris Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2223027A1 publication Critical patent/CA2223027A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002223027A 1995-06-07 1996-06-06 Electrochemiluminescent enzyme immunoassay Abandoned CA2223027A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48476695A 1995-06-07 1995-06-07
US08/484,766 1995-06-07

Publications (1)

Publication Number Publication Date
CA2223027A1 true CA2223027A1 (en) 1996-12-19

Family

ID=23925520

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002223027A Abandoned CA2223027A1 (en) 1995-06-07 1996-06-06 Electrochemiluminescent enzyme immunoassay

Country Status (9)

Country Link
US (2) US6524865B1 (https=)
EP (1) EP0871887B1 (https=)
JP (1) JP3784072B2 (https=)
AT (1) ATE358276T1 (https=)
AU (1) AU718767B2 (https=)
CA (1) CA2223027A1 (https=)
DE (1) DE69637001T2 (https=)
ES (1) ES2285713T3 (https=)
WO (1) WO1996041175A1 (https=)

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BR112018017336A2 (pt) 2016-03-07 2018-12-26 Hoffmann La Roche método in vitro para detectar um anticorpo para p53 (anticorpo anti-p53) em uma amostra e polipeptídeo de fusão
JP7068323B2 (ja) 2017-02-02 2022-05-16 エフ．ホフマン－ラ ロシュ アーゲー 少なくとも２種のペグ化された分析物特異的結合剤を使用する免疫アッセイ
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WO2020146497A1 (en) * 2019-01-09 2020-07-16 The Regents Of The University Of California An electrochemiluminescence elisa for ps129-a-synuclein
CN109839501B (zh) * 2019-01-30 2022-04-08 东南大学 一种测定循环肿瘤细胞的电致化学发光免疫传感器及其制备方法与应用
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JP7851928B2 (ja) 2020-11-02 2026-04-27 エフ． ホフマン－ラ ロシュ アーゲー ＳＡＲＳ－ＣｏＶ－２ヌクレオカプシド抗体
CN112964768A (zh) * 2021-03-23 2021-06-15 海南微氪生物科技股份有限公司 一种Bst DNA聚合酶电致化学发光测定方法
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WO2023072904A1 (en) 2021-10-26 2023-05-04 F. Hoffmann-La Roche Ag Monoclonal antibodies specific for sars-cov-2 rbd
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JP2025520600A (ja) 2022-06-23 2025-07-03 エフ． ホフマン－ラ ロシュ アーゲー 子宮内膜症を診断するためおよび子宮内膜症の病期を分類するための方法
JP2025524027A (ja) 2022-07-22 2025-07-25 エフ． ホフマン－ラ ロシュ アーゲー 多嚢胞性卵巣症候群の診断のための（血液）バイオマーカーとしてのメテオリン様タンパク質（ｍｅｔｒｎｌ）
EP4558830A1 (en) 2022-07-22 2025-05-28 F. Hoffmann-La Roche AG Leukotriene a4 hydrolase (lta4h) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome
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CN121532654A (zh) 2023-07-20 2026-02-13 豪夫迈·罗氏有限公司 针对抗体组合物的筛选方法
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Also Published As

Publication number Publication date
WO1996041175A1 (en) 1996-12-19
US20040096918A1 (en) 2004-05-20
US6524865B1 (en) 2003-02-25
JPH11507726A (ja) 1999-07-06
EP0871887A1 (en) 1998-10-21
DE69637001T2 (de) 2007-12-06
AU6384496A (en) 1996-12-30
ES2285713T3 (es) 2007-11-16
EP0871887B1 (en) 2007-03-28
JP3784072B2 (ja) 2006-06-07
US7018802B2 (en) 2006-03-28
AU718767B2 (en) 2000-04-20
DE69637001D1 (de) 2007-05-10
ATE358276T1 (de) 2007-04-15
EP0871887A4 (en) 2000-04-26

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