AU718767B2 - Electrochemiluminescent enzyme immunoassay - Google Patents

Electrochemiluminescent enzyme immunoassay Download PDF

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Publication number
AU718767B2
AU718767B2 AU63844/96A AU6384496A AU718767B2 AU 718767 B2 AU718767 B2 AU 718767B2 AU 63844/96 A AU63844/96 A AU 63844/96A AU 6384496 A AU6384496 A AU 6384496A AU 718767 B2 AU718767 B2 AU 718767B2
Authority
AU
Australia
Prior art keywords
analyte
enzyme
substrate
ecl
electrochemiluminescence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU63844/96A
Other languages
English (en)
Other versions
AU6384496A (en
Inventor
Pam Liang
Mark T Martin
Richard Saul
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioveris Corp
Original Assignee
IGEN International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IGEN International Inc filed Critical IGEN International Inc
Publication of AU6384496A publication Critical patent/AU6384496A/en
Assigned to IGEN INTERNATIONAL, INC. reassignment IGEN INTERNATIONAL, INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: IGEN, INC.
Application granted granted Critical
Publication of AU718767B2 publication Critical patent/AU718767B2/en
Assigned to BIOVERIS CORPORATION reassignment BIOVERIS CORPORATION Alteration of Name(s) in Register under S187 Assignors: IGEN INTERNATIONAL, INC.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU63844/96A 1995-06-07 1996-06-06 Electrochemiluminescent enzyme immunoassay Ceased AU718767B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48476695A 1995-06-07 1995-06-07
US08/484766 1995-06-07
PCT/US1996/010119 WO1996041175A1 (en) 1995-06-07 1996-06-06 Electrochemiluminescent enzyme immunoassay

Publications (2)

Publication Number Publication Date
AU6384496A AU6384496A (en) 1996-12-30
AU718767B2 true AU718767B2 (en) 2000-04-20

Family

ID=23925520

Family Applications (1)

Application Number Title Priority Date Filing Date
AU63844/96A Ceased AU718767B2 (en) 1995-06-07 1996-06-06 Electrochemiluminescent enzyme immunoassay

Country Status (9)

Country Link
US (2) US6524865B1 (https=)
EP (1) EP0871887B1 (https=)
JP (1) JP3784072B2 (https=)
AT (1) ATE358276T1 (https=)
AU (1) AU718767B2 (https=)
CA (1) CA2223027A1 (https=)
DE (1) DE69637001T2 (https=)
ES (1) ES2285713T3 (https=)
WO (1) WO1996041175A1 (https=)

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US5866434A (en) * 1994-12-08 1999-02-02 Meso Scale Technology Graphitic nanotubes in luminescence assays
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AU6115300A (en) * 1999-07-19 2001-02-05 California Institute Of Technology Detection of biomolecules by sensitizer-linked substrates
CN101057145B (zh) * 2004-06-23 2014-10-22 得克萨斯系统大学评议会 使用双粒子复合体检测生物分子的方法和组合物
US7906276B2 (en) 2004-06-30 2011-03-15 Kimberly-Clark Worldwide, Inc. Enzymatic detection techniques
US7521226B2 (en) 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
US7094528B2 (en) * 2004-06-30 2006-08-22 Kimberly-Clark Worldwide, Inc. Magnetic enzyme detection techniques
US20080261243A1 (en) * 2004-10-06 2008-10-23 Wellstat Biologics Corporation Detection of Elevated Levels of Her-2/Neu Protein on Circulating Cancer Cells and Treatment
US20090145485A1 (en) * 2005-08-11 2009-06-11 Eksigent Technologies, Llc Microfluidic methods and apparatuses for fluid mixing and valving
KR20080072748A (ko) 2005-11-29 2008-08-06 가미다-셀 리미티드 줄기세포 귀소 및 생착을 향상시키는 방법
US7820394B2 (en) * 2005-12-02 2010-10-26 Catassays Ultrasensitive bioanalytical assays based on the use of high-gain catalytic chemical amplification
JP5025724B2 (ja) * 2006-04-18 2012-09-12 ウェルスタット バイオロジクス コーポレイション 循環腫瘍性細胞からのタンパク質の検出
CA2684265A1 (en) * 2007-04-19 2008-10-30 Wellstat Biologics Corporation Detection of elevated levels of her-2/neu protein from non-isolated circulating cancer cells and treatment
JP4887319B2 (ja) 2008-03-17 2012-02-29 株式会社日立ハイテクノロジーズ 自動分析装置、及び光電子増倍管を用いた分析システム
PT2271938E (pt) 2008-04-11 2014-05-09 Univ Texas Método e aparelho de amplificação de quimiluminescênci electrogerada por nanopartículas
AU2009244904B2 (en) 2008-05-08 2014-04-17 Board Of Regents Of The University Of Texas System Luminescent nanostructured materials for use in electrogenerated chemiluminescence
WO2009136613A1 (ja) 2008-05-08 2009-11-12 株式会社 日立ハイテクノロジーズ 自動分析装置
JP5124498B2 (ja) 2009-01-30 2013-01-23 株式会社日立ハイテクノロジーズ 自動分析装置
WO2012093704A1 (ja) * 2011-01-07 2012-07-12 中外製薬株式会社 抗体の物性を改善させる方法
WO2013053953A1 (en) * 2011-10-14 2013-04-18 Université de Liège Method for measuring beta-lactam antibiotics
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
US9075042B2 (en) 2012-05-15 2015-07-07 Wellstat Diagnostics, Llc Diagnostic systems and cartridges
AU2013353573B2 (en) 2012-12-06 2019-01-17 Enlivex Therapeutics R&D Ltd Therapeutic apoptotic cell preparations, method for producing same and uses thereof
EP3258269B1 (en) * 2015-02-10 2019-06-05 Shenzhen New Industries Biomedical Engineering Co. Ltd. Reagent kit used for detecting lipoprotein-associated phospholipase a2, and preparation method and application for reagent kit
JP6979941B2 (ja) 2015-08-20 2021-12-15 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft Ｐｅｇ化分析物特異的結合剤を用いた粒子に基づくイムノアッセイ
BR112018017336A2 (pt) 2016-03-07 2018-12-26 Hoffmann La Roche método in vitro para detectar um anticorpo para p53 (anticorpo anti-p53) em uma amostra e polipeptídeo de fusão
JP7068323B2 (ja) 2017-02-02 2022-05-16 エフ．ホフマン－ラ ロシュ アーゲー 少なくとも２種のペグ化された分析物特異的結合剤を使用する免疫アッセイ
CN106645111A (zh) * 2017-03-01 2017-05-10 桂林理工大学 一种电化学发光快速检测抗生素ZwittermicinA浓度的方法
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WO2020146497A1 (en) * 2019-01-09 2020-07-16 The Regents Of The University Of California An electrochemiluminescence elisa for ps129-a-synuclein
CN109839501B (zh) * 2019-01-30 2022-04-08 东南大学 一种测定循环肿瘤细胞的电致化学发光免疫传感器及其制备方法与应用
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US5221605A (en) * 1984-10-31 1993-06-22 Igen, Inc. Luminescent metal chelate labels and means for detection
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Also Published As

Publication number Publication date
WO1996041175A1 (en) 1996-12-19
US20040096918A1 (en) 2004-05-20
US6524865B1 (en) 2003-02-25
JPH11507726A (ja) 1999-07-06
EP0871887A1 (en) 1998-10-21
DE69637001T2 (de) 2007-12-06
AU6384496A (en) 1996-12-30
ES2285713T3 (es) 2007-11-16
EP0871887B1 (en) 2007-03-28
JP3784072B2 (ja) 2006-06-07
US7018802B2 (en) 2006-03-28
DE69637001D1 (de) 2007-05-10
CA2223027A1 (en) 1996-12-19
ATE358276T1 (de) 2007-04-15
EP0871887A4 (en) 2000-04-26

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Owner name: BIOVERIS CORPORATION

Free format text: FORMER OWNER WAS: IGEN INTERNATIONAL, INC.