CA2214580A1 - Catalytic enantioselective synthesis of a spirofused azetidinone - Google Patents

Catalytic enantioselective synthesis of a spirofused azetidinone Download PDF

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Publication number
CA2214580A1
CA2214580A1 CA002214580A CA2214580A CA2214580A1 CA 2214580 A1 CA2214580 A1 CA 2214580A1 CA 002214580 A CA002214580 A CA 002214580A CA 2214580 A CA2214580 A CA 2214580A CA 2214580 A1 CA2214580 A1 CA 2214580A1
Authority
CA
Canada
Prior art keywords
formula
compound
group
alkyl
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002214580A
Other languages
English (en)
French (fr)
Inventor
Guang-Zhong Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2214580A1 publication Critical patent/CA2214580A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/12—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CA002214580A 1995-03-07 1996-03-04 Catalytic enantioselective synthesis of a spirofused azetidinone Abandoned CA2214580A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39985995A 1995-03-07 1995-03-07
US08/399,859 1995-03-07

Publications (1)

Publication Number Publication Date
CA2214580A1 true CA2214580A1 (en) 1996-09-12

Family

ID=23581257

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002214580A Abandoned CA2214580A1 (en) 1995-03-07 1996-03-04 Catalytic enantioselective synthesis of a spirofused azetidinone

Country Status (8)

Country Link
US (1) US5648484A (enExample)
EP (1) EP0827496A1 (enExample)
JP (1) JPH11501313A (enExample)
AU (1) AU5026696A (enExample)
CA (1) CA2214580A1 (enExample)
IL (1) IL117377A (enExample)
TW (1) TW316897B (enExample)
WO (1) WO1996027587A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999014220A1 (en) * 1997-09-12 1999-03-25 Lumigen, Inc. Novel compounds for generating chemiluminescence with a peroxidase
US6583096B1 (en) 1998-10-20 2003-06-24 The Procter & Gamble Company Laundry detergents comprising modified alkylbenzene sulfonates
US7340419B2 (en) 2001-03-15 2008-03-04 Walker Digital, Llc Method and apparatus for product display
EP1598336A1 (en) * 2004-05-20 2005-11-23 Laboratorios Del Dr. Esteve, S.A. Regioselective hydroxylation, functionalisation and protection of spirolactams
US7291728B2 (en) * 2004-05-10 2007-11-06 Laboratories Del Dr. Esteve, S.A. Spirolactams and their synthesis
JP2007536328A (ja) * 2004-05-10 2007-12-13 ラボラトリオス・デル・ドクトル・エステベ・ソシエダッド・アノニマ スピロラクタム類およびそれらの合成
US20080045726A1 (en) * 2004-05-10 2008-02-21 Laboratorios Del Dr. Esteve, S.A. Spirolactams and Their Synthesis
ES2245594B1 (es) * 2004-05-27 2006-12-01 Laboratorios Del Dr Esteve, S.A. Hidroxilacion, funcionalizacion y proteccion regioselectivas de espirolactamas.
MX2009002918A (es) * 2006-09-15 2009-03-31 Schering Corp Derivados azetidinona y sus metodos de uso.
AU2007294771A1 (en) * 2006-09-15 2008-03-20 Schering Corporation Azetidine and azetidone derivatives useful in treating pain and disorders of lipid metabolism
EP2061792A2 (en) * 2006-09-15 2009-05-27 Schering Corporation Azetidinone derivatives for the treatment of disorders of the lipid metabolism
CN101528746A (zh) * 2006-09-15 2009-09-09 先灵公司 治疗脂质代谢障碍、疼痛、糖尿病和其它障碍的螺环氮杂环丁酮衍生物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4692515A (en) * 1984-09-24 1987-09-08 Pennwalt Corporation Adamantane-spirolactams
LT3595B (en) * 1993-01-21 1995-12-27 Schering Corp Spirocycloalkyl-substituted azetidinones useful as hypocholesterolemic agents

Also Published As

Publication number Publication date
MX9706724A (es) 1997-11-29
AU5026696A (en) 1996-09-23
EP0827496A1 (en) 1998-03-11
JPH11501313A (ja) 1999-02-02
US5648484A (en) 1997-07-15
IL117377A (en) 2000-12-06
WO1996027587A1 (en) 1996-09-12
TW316897B (enExample) 1997-10-01
IL117377A0 (en) 1996-07-23

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Legal Events

Date Code Title Description
FZDE Discontinued