CA2158167A1 - Nouvelles imidazoloquinoxalinones, preparation et utilisation - Google Patents

Nouvelles imidazoloquinoxalinones, preparation et utilisation

Info

Publication number
CA2158167A1
CA2158167A1 CA002158167A CA2158167A CA2158167A1 CA 2158167 A1 CA2158167 A1 CA 2158167A1 CA 002158167 A CA002158167 A CA 002158167A CA 2158167 A CA2158167 A CA 2158167A CA 2158167 A1 CA2158167 A1 CA 2158167A1
Authority
CA
Canada
Prior art keywords
dihydro
methyl
quinoxaline
trifluoromethyl
sic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002158167A
Other languages
English (en)
Inventor
Hans-Joerg Treiber
Berthold Behl
Hans Peter Hofmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4329970A external-priority patent/DE4329970A1/de
Application filed by Individual filed Critical Individual
Publication of CA2158167A1 publication Critical patent/CA2158167A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA002158167A 1993-03-31 1994-03-19 Nouvelles imidazoloquinoxalinones, preparation et utilisation Abandoned CA2158167A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4310521 1993-03-31
DEP4310521.1 1993-03-31
DEP4329970.9 1993-09-04
DE4329970A DE4329970A1 (de) 1993-03-31 1993-09-04 Neue Imidazolo-chinoxalinone, ihre Hestellung und Verwendung

Publications (1)

Publication Number Publication Date
CA2158167A1 true CA2158167A1 (fr) 1994-10-13

Family

ID=25924528

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002158167A Abandoned CA2158167A1 (fr) 1993-03-31 1994-03-19 Nouvelles imidazoloquinoxalinones, preparation et utilisation

Country Status (17)

Country Link
EP (1) EP0691970B1 (fr)
JP (1) JPH08508271A (fr)
CN (1) CN1041928C (fr)
AT (1) ATE173263T1 (fr)
AU (1) AU6428294A (fr)
BR (1) BR9406034A (fr)
CA (1) CA2158167A1 (fr)
CZ (1) CZ246495A3 (fr)
FI (1) FI954614A0 (fr)
HR (1) HRP940210A2 (fr)
HU (1) HUT73970A (fr)
IL (1) IL109076A (fr)
NO (1) NO953892D0 (fr)
NZ (1) NZ263552A (fr)
PL (1) PL310950A1 (fr)
SI (1) SI9420023A (fr)
WO (1) WO1994022865A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100249142A1 (en) * 2007-10-03 2010-09-30 Universite De Montpellier I IMIDAZOL[1,2-alpha]QUINOXALINES AND DERIVATIVES FOR THE TREATMENT OF CANCERS
US8299080B2 (en) 2006-12-13 2012-10-30 Aska Pharmaceutical Co., Ltd. Substituted imidazo[1,5-A] quinoxalines as a PDE9 inhibitor

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE214069T1 (de) * 1994-02-11 2002-03-15 Novo Nordisk As Heterocyclische verbindungen und ihre herstellung und verwendung
FR2722789B1 (fr) * 1994-07-20 1996-08-23 Rhone Poulenc Rorer Sa Derives d'acide imidazo (1,2-a)indeno(1,2-e) pyrazine-2-carboxylique, leur preparation et les medicaments les contenant
IT1276167B1 (it) * 1995-11-24 1997-10-27 Foscama Biomed Chim Farma Imidazo(1,2-alfa)chinossalin-4-ammine attivi come antagonisti adenosinici,procedimento per la loro preparazione e loro composizioni
FR2743363A1 (fr) * 1996-01-10 1997-07-11 Rhone Poulenc Rorer Sa 5h,10h-imidazo(1,2-a)indeno(1,2-e)pyrazine-a-ones substituees en position 2, leur preparation et les medicaments les contenant
US6271418B1 (en) * 2000-02-22 2001-08-07 Nippon Kayaku Co., Ltd. Process for preparing (hetero) aromatic substituted benzene derivatives
GB0017518D0 (en) 2000-07-17 2000-08-30 Merck Sharp & Dohme Therapeutic agents
GB0018473D0 (en) * 2000-07-27 2000-09-13 Merck Sharp & Dohme Therapeutic agents
CN100386326C (zh) * 2003-10-22 2008-05-07 中国人民解放军军事医学科学院毒物药物研究所 1-羟甲基咪唑并[1，2-a]喹喔啉化合物及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2043064B (en) * 1979-02-09 1983-04-13 Roussel Lab Ltd Oximidazoquinoxaline derivatives
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
US5182386A (en) * 1991-08-27 1993-01-26 Neurogen Corporation Certain imidazoquinoxalinones; a new class of gaba brain receptor ligands

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8299080B2 (en) 2006-12-13 2012-10-30 Aska Pharmaceutical Co., Ltd. Substituted imidazo[1,5-A] quinoxalines as a PDE9 inhibitor
US8829000B2 (en) 2006-12-13 2014-09-09 Aska Pharmaceutical Co., Ltd. Substituted imidazo[1,5-A]quinoxalines as phosphodiesterase 9 inhibitors
US9040536B2 (en) 2006-12-13 2015-05-26 Aska Pharmaceutical Co., Ltd. Substituted pyrrolo[1,2-a]quinoxalines as PDE9 inhibitors
US20100249142A1 (en) * 2007-10-03 2010-09-30 Universite De Montpellier I IMIDAZOL[1,2-alpha]QUINOXALINES AND DERIVATIVES FOR THE TREATMENT OF CANCERS
US8378098B2 (en) * 2007-10-03 2013-02-19 Universite De Montpellier I Imidazol[1,2-α]quinoxalines and derivatives for the treatment of cancers

Also Published As

Publication number Publication date
HU9502848D0 (en) 1995-11-28
AU6428294A (en) 1994-10-24
JPH08508271A (ja) 1996-09-03
NZ263552A (en) 1997-06-24
CZ246495A3 (en) 1996-03-13
BR9406034A (pt) 1996-01-02
SI9420023A (en) 1996-04-30
CN1120336A (zh) 1996-04-10
ATE173263T1 (de) 1998-11-15
NO953892L (no) 1995-09-29
HUT73970A (en) 1996-10-28
FI954614A (fi) 1995-09-28
CN1041928C (zh) 1999-02-03
EP0691970B1 (fr) 1998-11-11
HRP940210A2 (en) 1996-12-31
WO1994022865A1 (fr) 1994-10-13
IL109076A0 (en) 1994-06-24
EP0691970A1 (fr) 1996-01-17
IL109076A (en) 1997-06-10
PL310950A1 (en) 1996-01-08
NO953892D0 (no) 1995-09-29
FI954614A0 (fi) 1995-09-28

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Legal Events

Date Code Title Description
FZDE Discontinued