CA2070057A1 - Process for the production of glycosyltransferases - Google Patents

Process for the production of glycosyltransferases

Info

Publication number
CA2070057A1
CA2070057A1 CA002070057A CA2070057A CA2070057A1 CA 2070057 A1 CA2070057 A1 CA 2070057A1 CA 002070057 A CA002070057 A CA 002070057A CA 2070057 A CA2070057 A CA 2070057A CA 2070057 A1 CA2070057 A1 CA 2070057A1
Authority
CA
Canada
Prior art keywords
leu
sequence
promoter
yeast
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002070057A
Other languages
English (en)
French (fr)
Inventor
Gabriele Watzele
Eric G. Berger
Bernd Meyhack
Manfred Watzele
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9208211A external-priority patent/GB2256197B/en
Application filed by Individual filed Critical Individual
Publication of CA2070057A1 publication Critical patent/CA2070057A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002070057A 1991-05-31 1992-05-29 Process for the production of glycosyltransferases Abandoned CA2070057A1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP91810414 1991-05-31
EP91810414.2 1991-05-31
EP92810167.4 1992-03-04
EP92810167 1992-03-04
GB9208211.4 1992-04-14
GB9208211A GB2256197B (en) 1991-05-31 1992-04-14 Yeast as host for expression of heterologous glycosyl transferase enzymes

Publications (1)

Publication Number Publication Date
CA2070057A1 true CA2070057A1 (en) 1992-12-01

Family

ID=27234292

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002070057A Abandoned CA2070057A1 (en) 1991-05-31 1992-05-29 Process for the production of glycosyltransferases

Country Status (19)

Country Link
JP (1) JPH05199871A (ja)
AT (1) AT401940B (ja)
AU (1) AU655470B2 (ja)
BE (1) BE1005579A5 (ja)
CA (1) CA2070057A1 (ja)
DK (1) DK71992A (ja)
ES (1) ES2046118B1 (ja)
FI (1) FI922515A (ja)
GR (1) GR920100250A (ja)
HU (1) HU212927B (ja)
IE (1) IE69059B1 (ja)
IL (1) IL102052A0 (ja)
IT (1) IT1255044B (ja)
LU (1) LU88123A1 (ja)
MX (1) MX9202583A (ja)
NO (1) NO922134L (ja)
NZ (1) NZ242958A (ja)
PT (1) PT100545A (ja)
SE (1) SE9201544L (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE7819584U1 (de) * 1978-06-30 1978-10-12 Howmedica International, Inc. Zweigniederlassung Kiel, 2301 Schoenkirchen Tubenartiger vorratsbehaelter fuer medizinisches spritzgeraet
DK0632831T3 (da) * 1992-03-09 2003-03-24 Univ California Nukleinsyre, ekspressionsvektor og sammensætninger til identificering og syntese af rekombinante sialyltransferaser
JP5037771B2 (ja) * 2000-04-13 2012-10-03 バイオチカ テクノロジー リミテッド グリコシル化されたハイブリッド産物およびその産生方法と利用
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
MXPA05010773A (es) 2003-04-09 2005-12-12 Neose Technologies Inc Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos.
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
JP5948627B2 (ja) 2004-10-29 2016-07-20 レイショファーム ゲーエムベーハー 線維芽細胞成長因子（ｆｇｆ）のリモデリングと糖質ペグ化
EP1858543B1 (en) 2005-01-10 2013-11-27 BioGeneriX AG Glycopegylated granulocyte colony stimulating factor
EP2386571B1 (en) 2005-04-08 2016-06-01 ratiopharm GmbH Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
US9187532B2 (en) 2006-07-21 2015-11-17 Novo Nordisk A/S Glycosylation of peptides via O-linked glycosylation sequences
JP2010505874A (ja) 2006-10-03 2010-02-25 ノヴォ ノルディスク アー／エス ポリペプチドコンジュゲートの精製方法
KR20150064246A (ko) 2007-04-03 2015-06-10 바이오제너릭스 게엠베하 글리코페길화 ｇ―ｃｓｆ를 이용하는 치료 방법
CA2690611C (en) 2007-06-12 2015-12-08 Novo Nordisk A/S Improved process for the production of nucleotide sugars
WO2009108806A1 (en) 2008-02-27 2009-09-03 Novo Nordisk A/S Conjugated factor viii molecules

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY103358A (en) * 1987-04-15 1993-06-30 Novartis Ag Process for the production of protiens.
AU4751990A (en) * 1988-12-13 1990-07-10 La Jolla Cancer Research Foundation Nucleotides encoding human b1, 4-galactosyltransferase and uses thereof
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
CA2075949A1 (en) * 1990-02-14 1991-08-15 John B. Lowe Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules
WO1991016900A1 (en) * 1990-04-27 1991-11-14 Biogen, Inc. Fucosyl transferases involved in adhesion molecule expression
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen

Also Published As

Publication number Publication date
ATA112792A (de) 1996-05-15
MX9202583A (es) 1992-11-01
GR920100250A (el) 1993-03-31
JPH05199871A (ja) 1993-08-10
NO922134L (no) 1992-12-01
ES2046118B1 (es) 1994-08-16
ITRM920411A0 (it) 1992-05-29
NZ242958A (en) 1993-06-25
NO922134D0 (no) 1992-05-29
FI922515A0 (fi) 1992-05-29
HUT65728A (en) 1994-07-28
IE69059B1 (en) 1996-08-07
ES2046118A1 (es) 1994-01-16
LU88123A1 (de) 1993-12-06
ITRM920411A1 (it) 1993-11-29
SE9201544L (sv) 1992-12-01
IE921769A1 (en) 1992-12-02
AU655470B2 (en) 1994-12-22
DK71992D0 (da) 1992-05-29
AU1705292A (en) 1992-12-03
HU9201787D0 (en) 1992-08-28
BE1005579A5 (fr) 1993-11-09
AT401940B (de) 1996-12-27
DK71992A (da) 1992-12-01
FI922515A (fi) 1992-12-01
IL102052A0 (en) 1992-12-30
IT1255044B (it) 1995-10-17
SE9201544D0 (sv) 1992-05-15
HU212927B (en) 1996-12-30
PT100545A (pt) 1993-08-31

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Legal Events

Date Code Title Description
FZDE Discontinued