CA2008861C - Imidazopyridazines, their production and use - Google Patents

Imidazopyridazines, their production and use Download PDF

Info

Publication number
CA2008861C
CA2008861C CA002008861A CA2008861A CA2008861C CA 2008861 C CA2008861 C CA 2008861C CA 002008861 A CA002008861 A CA 002008861A CA 2008861 A CA2008861 A CA 2008861A CA 2008861 C CA2008861 C CA 2008861C
Authority
CA
Canada
Prior art keywords
compound
hydrogen
halogen
substituents
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002008861A
Other languages
English (en)
French (fr)
Other versions
CA2008861A1 (en
Inventor
Akio Miyake
Masaaki Kuwahara
Hisashi Kuriki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of CA2008861A1 publication Critical patent/CA2008861A1/en
Application granted granted Critical
Publication of CA2008861C publication Critical patent/CA2008861C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Lubricants (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
CA002008861A 1989-01-31 1990-01-30 Imidazopyridazines, their production and use Expired - Fee Related CA2008861C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2335589 1989-01-31
JP23355/1989 1989-01-31
JP34225889 1989-12-29
JP342258/1989 1989-12-29

Publications (2)

Publication Number Publication Date
CA2008861A1 CA2008861A1 (en) 1990-07-31
CA2008861C true CA2008861C (en) 2000-11-28

Family

ID=26360706

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002008861A Expired - Fee Related CA2008861C (en) 1989-01-31 1990-01-30 Imidazopyridazines, their production and use

Country Status (12)

Country Link
US (1) US5202324A (no)
EP (1) EP0381132B1 (no)
CN (1) CN1032361C (no)
AT (1) ATE119530T1 (no)
AU (1) AU627832B2 (no)
CA (1) CA2008861C (no)
DE (1) DE69017480T2 (no)
FI (1) FI900461A0 (no)
NO (1) NO174257C (no)
NZ (1) NZ232283A (no)
PH (1) PH27291A (no)
RU (1) RU2034846C1 (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0440119A1 (en) * 1990-01-31 1991-08-07 Takeda Chemical Industries, Ltd. Imidazopyridazine compounds, their production and use
EP0444549B1 (en) * 1990-03-01 1995-01-25 Takeda Chemical Industries, Ltd. Imidazopyridazines their production and use
TW211013B (no) * 1991-12-27 1993-08-11 Takeda Pharm Industry Co Ltd
DE69322673T2 (de) * 1992-03-18 1999-05-06 Takeda Chemical Industries, Ltd., Osaka Imidazopyridazine als Antiasthmatika
LT3200B (en) * 1992-03-18 1995-03-27 Takeda Chemical Industries Ltd Triazolopyridazine methodfor production thereof and use
US5482939A (en) * 1992-03-18 1996-01-09 Takeda Chemical Industries, Ltd. Triazolopyridazine compounds, their production and use
EP0620224B1 (en) * 1993-04-12 1998-07-15 Takeda Chemical Industries, Ltd. Triazolopyridazine derivatives, their production and use
TW304878B (no) * 1993-09-21 1997-05-11 Takeda Pharm Industry Co Ltd
BR9714049A (pt) * 1996-12-20 2000-05-09 Byk Gulden Lomberg Chem Fab Imidazopiridazinas
WO1998049167A1 (en) 1997-04-25 1998-11-05 Takeda Chemical Industries, Ltd. Condensed pyridazine derivatives, their production and use
AU6003099A (en) 1998-10-06 2000-04-26 Takeda Chemical Industries Ltd. Fused pyridazine compounds, process for the preparation of the same and uses thereof
ATE256128T1 (de) 1998-10-21 2003-12-15 Takeda Chemical Industries Ltd Kondensierte pyridazinderivate, verfahren zu ihrer herstellung und ihre anwendung
JP2003524007A (ja) * 2000-02-21 2003-08-12 アストラゼネカ・アクチエボラーグ アリールピペラジン類およびそれらのメタロプロテイナーゼ阻害剤（ｍｍｐ）としての使用
GB0119474D0 (en) * 2001-08-09 2001-10-03 Astrazeneca Ab Compounds
GB0119473D0 (en) * 2001-08-09 2001-10-03 Astrazeneca Compounds
GB0119472D0 (en) * 2001-08-09 2001-10-03 Astrazeneca Ab Compounds
AU2007315234A1 (en) * 2006-10-30 2008-05-08 Novartis Ag Heterocyclic compounds as antiinflammatory agents
US8460302B2 (en) * 2006-12-18 2013-06-11 Otismed Corporation Arthroplasty devices and related methods

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3489755A (en) * 1966-08-03 1970-01-13 Pfizer & Co C Imidazo (1,2-b) pyridazines
US4166851A (en) * 1977-05-16 1979-09-04 Merck & Co., Inc. Certain imidazo(1,2a)pyridine derivatives
US4330543A (en) * 1978-12-14 1982-05-18 Merck & Co., Inc. Imidazoazines and imidazodiazines
FR2473522A1 (fr) * 1980-01-16 1981-07-17 Synthelabo Nouveaux derives substitues de dihydro-2,3 imidazo(1,2-b)pyridazines et les medicaments, utiles notamment comme antidepresseurs, qui en contiennent
JPS5840489A (ja) * 1981-09-04 1983-03-09 Toshiba Corp 原子力発電所用タ−ビン復水器
US4464372A (en) * 1982-08-16 1984-08-07 Schering Corporation Imidazo[1,2-b]pyridazines
JPS60254160A (ja) * 1984-05-31 1985-12-14 Mita Ind Co Ltd 電子写真方法
DE3446812A1 (de) * 1984-12-21 1986-06-26 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
NO166283C (no) * 1985-03-01 1991-06-26 Takeda Chemical Industries Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive 7beta-(2-(5-amino-1,2,4-tiadiazol-3-yl)-2(z)-substituertoksyiminoacetamido)-3-(heterocyclylmetyl)-3-cefem-4-karboksylsyrederivater.
DE3542661A1 (de) * 1985-12-03 1987-06-04 Bayer Ag Imidazopyridazinalkensaeureamide, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung
PH25866A (en) * 1986-03-20 1991-12-02 Takeda Chemical Industries Ltd Sulfonylurea compounds and their herbicides
WO1989001478A1 (en) * 1987-08-07 1989-02-23 The Australian National University ARYLOXY- AND ARALKYLTHIO-IMIDAZO[1,2-b]PYRIDAZINES
AU2261488A (en) * 1987-08-07 1989-03-09 Australian National University, The Imidazo(1,2-b)pyridazines
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds
EP0444549B1 (en) * 1990-03-01 1995-01-25 Takeda Chemical Industries, Ltd. Imidazopyridazines their production and use

Also Published As

Publication number Publication date
NZ232283A (en) 1991-08-27
CN1047290A (zh) 1990-11-28
PH27291A (en) 1993-05-04
NO174257C (no) 1994-04-06
EP0381132B1 (en) 1995-03-08
ATE119530T1 (de) 1995-03-15
FI900461A0 (fi) 1990-01-30
NO900425D0 (no) 1990-01-30
DE69017480T2 (de) 1995-08-24
NO174257B (no) 1993-12-27
DE69017480D1 (de) 1995-04-13
NO900425L (no) 1990-08-01
AU627832B2 (en) 1992-09-03
AU4889190A (en) 1990-08-16
CA2008861A1 (en) 1990-07-31
EP0381132A1 (en) 1990-08-08
US5202324A (en) 1993-04-13
RU2034846C1 (ru) 1995-05-10
CN1032361C (zh) 1996-07-24

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