CA1291122C - 3'-hydroxy-4'-epi-amino anthracyclines - Google Patents

3'-hydroxy-4'-epi-amino anthracyclines

Info

Publication number
CA1291122C
CA1291122C CA000539119A CA539119A CA1291122C CA 1291122 C CA1291122 C CA 1291122C CA 000539119 A CA000539119 A CA 000539119A CA 539119 A CA539119 A CA 539119A CA 1291122 C CA1291122 C CA 1291122C
Authority
CA
Canada
Prior art keywords
epi
produced
hydrochloride
daunorubicin
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000539119A
Other languages
English (en)
French (fr)
Inventor
Antonino Suarato
Sergio Penco
Fernando Giuliani
Michele Caruso
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of CA1291122C publication Critical patent/CA1291122C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA000539119A 1986-06-12 1987-06-08 3'-hydroxy-4'-epi-amino anthracyclines Expired - Fee Related CA1291122C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868614323A GB8614323D0 (en) 1986-06-12 1986-06-12 Anthracyclines
GB8614323 1986-06-12

Publications (1)

Publication Number Publication Date
CA1291122C true CA1291122C (en) 1991-10-22

Family

ID=10599357

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000539119A Expired - Fee Related CA1291122C (en) 1986-06-12 1987-06-08 3'-hydroxy-4'-epi-amino anthracyclines

Country Status (24)

Country Link
JP (1) JP2516769B2 (fi)
KR (1) KR950004897B1 (fi)
AT (1) AT392793B (fi)
AU (1) AU595328B2 (fi)
BE (1) BE1000158A4 (fi)
CA (1) CA1291122C (fi)
CH (1) CH676985A5 (fi)
DE (1) DE3719377C2 (fi)
DK (1) DK169076B1 (fi)
ES (1) ES2006488A6 (fi)
FI (1) FI84075C (fi)
FR (1) FR2600066B1 (fi)
GB (2) GB8614323D0 (fi)
GR (1) GR870909B (fi)
HU (1) HU196220B (fi)
IE (1) IE60412B1 (fi)
IL (1) IL82820A0 (fi)
IT (1) IT1215552B (fi)
NL (1) NL8701349A (fi)
NZ (1) NZ220604A (fi)
PT (1) PT85056B (fi)
SE (1) SE500732C2 (fi)
SU (1) SU1590045A3 (fi)
ZA (1) ZA874202B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3842836A1 (de) * 1988-12-20 1990-06-21 Behringwerke Ag Rhodomycine mit einer modifizierten kohlenhydrat-einheit
GB9325417D0 (en) * 1993-12-13 1994-02-16 Erba Carlo Spa 3'- aziridino-anthracycline derivatives
IT1275953B1 (it) * 1995-03-22 1997-10-24 Sicor Spa Procedimento per la preparazione di antibiotici della classe delle antracicline
GB9808027D0 (en) * 1998-04-15 1998-06-17 Pharmacia & Upjohn Spa 13-dihydro-3' aziridino anthracyclines
AU2343900A (en) * 1998-11-02 2000-05-22 Board Of Regents, The University Of Texas System Methods and compositions for the manufacture of highly potent anthracycline-based antitumor agents
GB0114654D0 (en) * 2001-06-15 2001-08-08 Pharmacia & Upjohn Spa Anti-tumor compound
CN110483871A (zh) * 2019-08-15 2019-11-22 陈全明 一种抗压耐磨的hdpe双壁波纹管

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
EP0051280B1 (en) * 1980-11-01 1984-07-11 FARMITALIA CARLO ERBA S.p.A. Anthracycline glycosides, process for the preparation thereof, intermediate compounds and their preparation and pharmaceutical compositions
GB8508079D0 (en) * 1985-03-28 1985-05-01 Erba Farmitalia Antitumor anthracyclines

Also Published As

Publication number Publication date
PT85056B (pt) 1990-03-30
GB2195998A (en) 1988-04-20
DK169076B1 (da) 1994-08-08
FI84075C (fi) 1991-10-10
DE3719377A1 (de) 1987-12-17
BE1000158A4 (fr) 1988-06-28
FI872571A (fi) 1987-12-13
DK298787D0 (da) 1987-06-11
JP2516769B2 (ja) 1996-07-24
GB8713443D0 (en) 1987-07-15
NL8701349A (nl) 1988-01-04
AU7410887A (en) 1987-12-17
IT1215552B (it) 1990-02-14
IT8720834A0 (it) 1987-06-09
AT392793B (de) 1991-06-10
SU1590045A3 (ru) 1990-08-30
SE8702409D0 (sv) 1987-06-10
HUT43866A (en) 1987-12-28
FR2600066B1 (fr) 1992-05-15
NZ220604A (en) 1989-10-27
ATA144987A (de) 1990-11-15
HU196220B (en) 1988-10-28
GR870909B (en) 1987-10-12
ZA874202B (en) 1988-02-24
SE500732C2 (sv) 1994-08-15
AU595328B2 (en) 1990-03-29
IL82820A0 (en) 1987-12-20
FI84075B (fi) 1991-06-28
PT85056A (en) 1987-07-01
IE60412B1 (en) 1994-07-13
IE871538L (en) 1987-12-13
FR2600066A1 (fr) 1987-12-18
SE8702409L (sv) 1987-12-13
GB2195998B (en) 1990-02-14
DK298787A (da) 1987-12-13
DE3719377C2 (de) 1995-09-28
FI872571A0 (fi) 1987-06-09
KR950004897B1 (ko) 1995-05-15
CH676985A5 (fi) 1991-03-28
GB8614323D0 (en) 1986-07-16
ES2006488A6 (es) 1989-05-01
KR880000459A (ko) 1988-03-26
JPS62292793A (ja) 1987-12-19

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Legal Events

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