CA1268771C - - Google Patents

Info

Publication number
CA1268771C
CA1268771C CA 427937 CA427937A CA1268771C CA 1268771 C CA1268771 C CA 1268771C CA 427937 CA427937 CA 427937 CA 427937 A CA427937 A CA 427937A CA 1268771 C CA1268771 C CA 1268771C
Authority
CA
Canada
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA 427937
Other versions
CA1258464A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to CA000600591A priority Critical patent/CA1268771A/en
Priority to CA000600593A priority patent/CA1269109A/en
Priority to CA000600592A priority patent/CA1268772A/en
Application granted granted Critical
Publication of CA1258464A publication Critical patent/CA1258464A/en
Publication of CA1268771C publication Critical patent/CA1268771C/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA000427937A 1982-05-12 1983-05-11 1,3-dioxan-5-ylalkenoic acids Expired CA1258464A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA000600591A CA1268771A (en) 1982-05-12 1989-05-24 5-allyl-1,3-dioxane derivatives
CA000600593A CA1269109A (en) 1982-05-12 1989-05-24 Erythro diols
CA000600592A CA1268772A (en) 1982-05-12 1989-05-24 (4-phenyl-1,3-dioxan-cis-5-yl)acetaldehyde derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8213702 1982-05-12

Related Child Applications (3)

Application Number Title Priority Date Filing Date
CA000600591A Division CA1268771A (en) 1982-05-12 1989-05-24 5-allyl-1,3-dioxane derivatives
CA000600592A Division CA1268772A (en) 1982-05-12 1989-05-24 (4-phenyl-1,3-dioxan-cis-5-yl)acetaldehyde derivatives
CA000600593A Division CA1269109A (en) 1982-05-12 1989-05-24 Erythro diols

Publications (2)

Publication Number Publication Date
CA1258464A CA1258464A (en) 1989-08-15
CA1268771C true CA1268771C (ja�@�@) 1990-05-08

Family

ID=10530304

Family Applications (4)

Application Number Title Priority Date Filing Date
CA000427937A Expired CA1258464A (en) 1982-05-12 1983-05-11 1,3-dioxan-5-ylalkenoic acids
CA000600593A Expired - Lifetime CA1269109A (en) 1982-05-12 1989-05-24 Erythro diols
CA000600592A Expired - Lifetime CA1268772A (en) 1982-05-12 1989-05-24 (4-phenyl-1,3-dioxan-cis-5-yl)acetaldehyde derivatives
CA000600591A Expired - Lifetime CA1268771A (en) 1982-05-12 1989-05-24 5-allyl-1,3-dioxane derivatives

Family Applications After (3)

Application Number Title Priority Date Filing Date
CA000600593A Expired - Lifetime CA1269109A (en) 1982-05-12 1989-05-24 Erythro diols
CA000600592A Expired - Lifetime CA1268772A (en) 1982-05-12 1989-05-24 (4-phenyl-1,3-dioxan-cis-5-yl)acetaldehyde derivatives
CA000600591A Expired - Lifetime CA1268771A (en) 1982-05-12 1989-05-24 5-allyl-1,3-dioxane derivatives

Country Status (32)

Country Link
US (3) US4567197A (ja�@�@)
EP (1) EP0094239B1 (ja�@�@)
JP (1) JPS58222081A (ja�@�@)
KR (1) KR880002001B1 (ja�@�@)
AR (1) AR240817A1 (ja�@�@)
AT (1) ATE28329T1 (ja�@�@)
AU (1) AU562056B2 (ja�@�@)
CA (4) CA1258464A (ja�@�@)
CS (2) CS245783B2 (ja�@�@)
CY (1) CY1453A (ja�@�@)
DD (2) DD219769A5 (ja�@�@)
DE (1) DE3372483D1 (ja�@�@)
DK (1) DK163431C (ja�@�@)
ES (4) ES522331A0 (ja�@�@)
FI (1) FI80027C (ja�@�@)
GB (1) GB8310407D0 (ja�@�@)
GR (1) GR78138B (ja�@�@)
HK (1) HK17889A (ja�@�@)
HU (1) HU198705B (ja�@�@)
IE (1) IE55114B1 (ja�@�@)
IL (1) IL68628A0 (ja�@�@)
KE (1) KE3823A (ja�@�@)
MW (1) MW1583A1 (ja�@�@)
NO (1) NO162383B (ja�@�@)
NZ (1) NZ204202A (ja�@�@)
PH (1) PH21691A (ja�@�@)
PL (3) PL140274B1 (ja�@�@)
PT (1) PT76684B (ja�@�@)
SG (1) SG57088G (ja�@�@)
SU (1) SU1277893A3 (ja�@�@)
ZA (1) ZA833179B (ja�@�@)
ZW (1) ZW10083A1 (ja�@�@)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8310407D0 (en) * 1982-05-12 1983-05-25 Ici Plc 1 3 - dioxan -5- ylalkenoic acids
FR2551446B1 (fr) * 1983-08-31 1987-03-20 Elf Aquitaine Compositions de resines ayant une resistance amelioree au choc renfermant un polymere thermoplastique, un additif choc du type copolymere greffe, et eventuellement d'autres additifs, et copolymere greffe correspondant, a caractere d'additif choc
GB8330120D0 (en) * 1983-11-11 1983-12-21 Ici Plc Chemical process
GB8330094D0 (en) * 1983-11-11 1983-12-21 Ici Plc Diphenyl compounds
GB8330097D0 (en) * 1983-11-11 1983-12-21 Ici Plc Cyclic ethers
GB8417314D0 (en) * 1984-07-06 1984-08-08 Ici Plc Carboxylic acid derivatives
GB8511890D0 (en) * 1985-05-10 1985-06-19 Ici Plc Benzene derivatives
HU198706B (en) 1985-05-10 1989-11-28 Ici Plc Process for producing 1,3-dioxan-ethers and pharmaceutical compositions containing them
GB8511892D0 (en) * 1985-05-10 1985-06-19 Ici Plc Fluoralkane derivatives
GB8511897D0 (en) * 1985-05-10 1985-06-19 Ici Plc Carboxylic acids
EP0201352B1 (en) * 1985-05-10 1992-06-24 Imperial Chemical Industries Plc Alkene derivatives
GB8511894D0 (en) 1985-05-10 1985-06-19 Ici Plc Phenol derivatives
GB8511895D0 (en) * 1985-05-10 1985-06-19 Ici Plc Heterocyclic compounds
GB8511891D0 (en) * 1985-05-10 1985-06-19 Ici Plc Alkenoic acids
EP0223518B1 (en) * 1985-11-12 1990-09-26 Imperial Chemical Industries Plc Amide derivatives
GB8611174D0 (en) * 1986-05-08 1986-06-18 Ici Plc Amide derivatives
GB8531892D0 (en) * 1985-12-30 1986-02-05 Ici Plc Carboxylic acids
DE3603662A1 (de) * 1986-02-06 1987-08-13 Basf Ag Acetalisierte oder ketalisierte dihydroxyaldehyde, verfahren zu ihrer herstellung und diese enthaltende loesungen
GB8626296D0 (en) * 1986-11-04 1986-12-03 Ici Plc Therapeutic agents
GB8626297D0 (en) * 1986-11-04 1986-12-03 Ici Plc Pharmaceutical compositions
GB8709794D0 (en) * 1987-04-24 1987-05-28 Ici Plc Heterocyclic acids
GB8901201D0 (en) * 1988-02-16 1989-03-15 Ici Plc Pyridine derivatives
US5248780A (en) * 1988-02-16 1993-09-28 Imperial Chemical Industries, Plc Pyridyl substituted alkenoic acid derivatives
EP0346511A1 (en) * 1988-06-15 1989-12-20 Fujisawa Pharmaceutical Co., Ltd. Oxygen-containing hererocyclic compound, processes for their preparation and pharmaceutical compositions comprising them
CN1034120C (zh) * 1988-10-21 1997-02-26 曾尼卡有限公司 制备二噁烷链烯酸衍生物的方法
IE81170B1 (en) * 1988-10-21 2000-05-31 Zeneca Ltd Pyridine derivatives
GB9021571D0 (en) * 1990-10-04 1990-11-21 Ici Plc Heterocyclic acids
US5925795A (en) * 1996-09-16 1999-07-20 Zeneca Limited Processes for the preparation of aryl-β-diketones, arylpyrimidine ketones and crop protection intermediates
GB0413970D0 (en) * 2004-06-22 2004-07-28 Syngenta Participations Ag Chemical compounds
JP2009523781A (ja) * 2006-01-18 2009-06-25 エヴォルヴァ エスアー Ｐｐａｒ調節因子
US20100273824A1 (en) * 2007-01-18 2010-10-28 Evolva Sa Substituted 1,3-dioxanes and their uses
JP2010516702A (ja) * 2007-01-18 2010-05-20 エヴォルヴァ エスアー 置換１，３−ジオキサンのプロドラッグおよびそれらの使用
JP6238970B2 (ja) * 2012-05-18 2017-11-29 サノフイ ベンゾ［１，３］ジオキシン誘導体およびｌｐａｒ５アンタゴニストとしてのその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4243592A (en) * 1979-03-12 1981-01-06 The Upjohn Company 9,11-Dideoxy-10-oxa-TXB compounds
GB8310407D0 (en) * 1982-05-12 1983-05-25 Ici Plc 1 3 - dioxan -5- ylalkenoic acids
GB8417314D0 (en) * 1984-07-06 1984-08-08 Ici Plc Carboxylic acid derivatives

Also Published As

Publication number Publication date
EP0094239A2 (en) 1983-11-16
EP0094239B1 (en) 1987-07-15
CA1269109A (en) 1990-05-15
DK163431C (da) 1992-07-20
FI80027B (fi) 1989-12-29
US4567197A (en) 1986-01-28
GR78138B (ja�@�@) 1984-09-26
ES8608507A1 (es) 1986-06-16
EP0094239A3 (en) 1984-12-12
DE3372483D1 (de) 1987-08-20
CS333683A2 (en) 1985-09-17
US5166377A (en) 1992-11-24
DD212515A5 (de) 1984-08-15
ZW10083A1 (en) 1984-11-28
ATE28329T1 (de) 1987-08-15
ES8407038A1 (es) 1984-08-16
KR880002001B1 (ko) 1988-10-11
ES528575A0 (es) 1986-10-16
GB8310407D0 (en) 1983-05-25
CA1268771A (en) 1990-05-08
PL250099A1 (en) 1985-07-02
DD219769A5 (de) 1985-03-13
SG57088G (en) 1989-01-27
HK17889A (en) 1989-03-10
ES522331A0 (es) 1984-08-16
CS245795B2 (en) 1986-10-16
AR240817A2 (es) 1991-02-28
PT76684B (en) 1986-01-14
KE3823A (en) 1988-10-21
FI831664A0 (fi) 1983-05-12
ES528576A0 (es) 1986-10-16
US4745198A (en) 1988-05-17
HU198705B (en) 1989-11-28
ES8700250A1 (es) 1986-10-16
MW1583A1 (en) 1985-02-13
ES528577A0 (es) 1986-06-16
JPH0378389B2 (ja�@�@) 1991-12-13
IL68628A0 (en) 1984-05-31
IE831005L (en) 1983-11-12
FI80027C (fi) 1990-04-10
ES8700249A1 (es) 1986-10-16
NZ204202A (en) 1986-05-09
AU1422383A (en) 1983-11-17
KR840004739A (ko) 1984-10-24
CS725784A2 (en) 1985-09-17
AU562056B2 (en) 1987-05-28
CA1268772A (en) 1990-05-08
CY1453A (en) 1989-07-21
ZA833179B (en) 1984-04-25
PL140274B1 (en) 1987-04-30
PL250098A1 (en) 1985-07-02
SU1277893A3 (ru) 1986-12-15
PL140463B1 (en) 1987-04-30
PT76684A (en) 1983-06-01
DK211883A (da) 1983-11-13
NO831679L (no) 1983-11-14
CS245783B2 (en) 1986-10-16
PH21691A (en) 1988-01-13
CA1258464A (en) 1989-08-15
JPS58222081A (ja) 1983-12-23
IE55114B1 (en) 1990-06-06
DK163431B (da) 1992-03-02
NO162383B (no) 1989-09-11
PL140462B1 (en) 1987-04-30
DK211883D0 (da) 1983-05-11
AR240817A1 (es) 1991-02-28
PL241920A1 (en) 1985-03-26
FI831664L (fi) 1983-11-13

Similar Documents

Publication Publication Date Title
FR2511252B1 (ja�@�@)
CH655405B (ja�@�@)
DE3348095A1 (ja�@�@)
FR2519822B1 (ja�@�@)
GR78138B (ja�@�@)
DE3249743A1 (ja�@�@)
FR2519336B1 (ja�@�@)
FR2521182B3 (ja�@�@)
DE3347880A1 (ja�@�@)
CH670543GA3 (ja�@�@)
FR2521442B3 (ja�@�@)
FR2523200B1 (ja�@�@)
FR2519844B1 (ja�@�@)
FR2519985B1 (ja�@�@)
FR2519523B1 (ja�@�@)
FR2519402B1 (ja�@�@)
FR2519527B1 (ja�@�@)
FR2519745B3 (ja�@�@)
FR2520063B3 (ja�@�@)
FR2519914B3 (ja�@�@)
FR2519391B3 (ja�@�@)
FR2519660B1 (ja�@�@)
CH657125B (ja�@�@)
CH669703GA3 (ja�@�@)
FR2520084B1 (ja�@�@)

Legal Events

Date Code Title Description
MKEX Expiry