CA1268771C - - Google Patents

Info

Publication number
CA1268771C
CA1268771C CA 427937 CA427937A CA1268771C CA 1268771 C CA1268771 C CA 1268771C CA 427937 CA427937 CA 427937 CA 427937 A CA427937 A CA 427937A CA 1268771 C CA1268771 C CA 1268771C
Authority
CA
Canada
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA 427937
Other versions
CA1258464A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to CA000600593A priority Critical patent/CA1269109A/en
Priority to CA000600592A priority patent/CA1268772A/en
Priority to CA000600591A priority patent/CA1268771A/en
Application granted granted Critical
Publication of CA1258464A publication Critical patent/CA1258464A/en
Publication of CA1268771C publication Critical patent/CA1268771C/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA000427937A 1982-05-12 1983-05-11 1,3-dioxan-5-ylalkenoic acids Expired CA1258464A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA000600593A CA1269109A (en) 1982-05-12 1989-05-24 Erythro diols
CA000600592A CA1268772A (en) 1982-05-12 1989-05-24 (4-phenyl-1,3-dioxan-cis-5-yl)acetaldehyde derivatives
CA000600591A CA1268771A (en) 1982-05-12 1989-05-24 5-allyl-1,3-dioxane derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8213702 1982-05-12

Related Child Applications (3)

Application Number Title Priority Date Filing Date
CA000600592A Division CA1268772A (en) 1982-05-12 1989-05-24 (4-phenyl-1,3-dioxan-cis-5-yl)acetaldehyde derivatives
CA000600591A Division CA1268771A (en) 1982-05-12 1989-05-24 5-allyl-1,3-dioxane derivatives
CA000600593A Division CA1269109A (en) 1982-05-12 1989-05-24 Erythro diols

Publications (2)

Publication Number Publication Date
CA1258464A CA1258464A (en) 1989-08-15
CA1268771C true CA1268771C (en:Method) 1990-05-08

Family

ID=10530304

Family Applications (4)

Application Number Title Priority Date Filing Date
CA000427937A Expired CA1258464A (en) 1982-05-12 1983-05-11 1,3-dioxan-5-ylalkenoic acids
CA000600592A Expired - Lifetime CA1268772A (en) 1982-05-12 1989-05-24 (4-phenyl-1,3-dioxan-cis-5-yl)acetaldehyde derivatives
CA000600591A Expired - Lifetime CA1268771A (en) 1982-05-12 1989-05-24 5-allyl-1,3-dioxane derivatives
CA000600593A Expired - Lifetime CA1269109A (en) 1982-05-12 1989-05-24 Erythro diols

Family Applications After (3)

Application Number Title Priority Date Filing Date
CA000600592A Expired - Lifetime CA1268772A (en) 1982-05-12 1989-05-24 (4-phenyl-1,3-dioxan-cis-5-yl)acetaldehyde derivatives
CA000600591A Expired - Lifetime CA1268771A (en) 1982-05-12 1989-05-24 5-allyl-1,3-dioxane derivatives
CA000600593A Expired - Lifetime CA1269109A (en) 1982-05-12 1989-05-24 Erythro diols

Country Status (32)

Country Link
US (3) US4567197A (en:Method)
EP (1) EP0094239B1 (en:Method)
JP (1) JPS58222081A (en:Method)
KR (1) KR880002001B1 (en:Method)
AR (1) AR240817A1 (en:Method)
AT (1) ATE28329T1 (en:Method)
AU (1) AU562056B2 (en:Method)
CA (4) CA1258464A (en:Method)
CS (2) CS245795B2 (en:Method)
CY (1) CY1453A (en:Method)
DD (2) DD219769A5 (en:Method)
DE (1) DE3372483D1 (en:Method)
DK (1) DK163431C (en:Method)
ES (4) ES8407038A1 (en:Method)
FI (1) FI80027C (en:Method)
GB (1) GB8310407D0 (en:Method)
GR (1) GR78138B (en:Method)
HK (1) HK17889A (en:Method)
HU (1) HU198705B (en:Method)
IE (1) IE55114B1 (en:Method)
IL (1) IL68628A0 (en:Method)
KE (1) KE3823A (en:Method)
MW (1) MW1583A1 (en:Method)
NO (1) NO162383B (en:Method)
NZ (1) NZ204202A (en:Method)
PH (1) PH21691A (en:Method)
PL (3) PL140463B1 (en:Method)
PT (1) PT76684B (en:Method)
SG (1) SG57088G (en:Method)
SU (1) SU1277893A3 (en:Method)
ZA (1) ZA833179B (en:Method)
ZW (1) ZW10083A1 (en:Method)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8310407D0 (en) * 1982-05-12 1983-05-25 Ici Plc 1 3 - dioxan -5- ylalkenoic acids
FR2551446B1 (fr) * 1983-08-31 1987-03-20 Elf Aquitaine Compositions de resines ayant une resistance amelioree au choc renfermant un polymere thermoplastique, un additif choc du type copolymere greffe, et eventuellement d'autres additifs, et copolymere greffe correspondant, a caractere d'additif choc
GB8330097D0 (en) * 1983-11-11 1983-12-21 Ici Plc Cyclic ethers
GB8330094D0 (en) * 1983-11-11 1983-12-21 Ici Plc Diphenyl compounds
GB8330120D0 (en) * 1983-11-11 1983-12-21 Ici Plc Chemical process
GB8417314D0 (en) * 1984-07-06 1984-08-08 Ici Plc Carboxylic acid derivatives
GB8511895D0 (en) * 1985-05-10 1985-06-19 Ici Plc Heterocyclic compounds
PT82554B (pt) * 1985-05-10 1988-11-30 Ici Plc Processo para a preparacao de um {2,4,5,-cis} dioxano e de composicoes farmaceuticas que os contem
GB8511897D0 (en) * 1985-05-10 1985-06-19 Ici Plc Carboxylic acids
GB8511891D0 (en) * 1985-05-10 1985-06-19 Ici Plc Alkenoic acids
DK212786A (da) * 1985-05-10 1986-11-11 Ici Plc 1,3-dioxanethere
GB8511890D0 (en) * 1985-05-10 1985-06-19 Ici Plc Benzene derivatives
GB8511892D0 (en) * 1985-05-10 1985-06-19 Ici Plc Fluoralkane derivatives
GB8511894D0 (en) 1985-05-10 1985-06-19 Ici Plc Phenol derivatives
AU584763B2 (en) * 1985-11-12 1989-06-01 Imperial Chemical Industries Plc N-(6-(4-0-hydrxyphenyl-1,3-dioxan-cis-5-yl)hexenoyl) suphonamide derivatives
GB8611174D0 (en) * 1986-05-08 1986-06-18 Ici Plc Amide derivatives
GB8531892D0 (en) * 1985-12-30 1986-02-05 Ici Plc Carboxylic acids
DE3603662A1 (de) * 1986-02-06 1987-08-13 Basf Ag Acetalisierte oder ketalisierte dihydroxyaldehyde, verfahren zu ihrer herstellung und diese enthaltende loesungen
GB8626297D0 (en) * 1986-11-04 1986-12-03 Ici Plc Pharmaceutical compositions
GB8626296D0 (en) * 1986-11-04 1986-12-03 Ici Plc Therapeutic agents
GB8709794D0 (en) * 1987-04-24 1987-05-28 Ici Plc Heterocyclic acids
US5248780A (en) * 1988-02-16 1993-09-28 Imperial Chemical Industries, Plc Pyridyl substituted alkenoic acid derivatives
GB8901201D0 (en) * 1988-02-16 1989-03-15 Ici Plc Pyridine derivatives
EP0346511A1 (en) * 1988-06-15 1989-12-20 Fujisawa Pharmaceutical Co., Ltd. Oxygen-containing hererocyclic compound, processes for their preparation and pharmaceutical compositions comprising them
CN1034120C (zh) * 1988-10-21 1997-02-26 曾尼卡有限公司 制备二噁烷链烯酸衍生物的方法
IE81170B1 (en) * 1988-10-21 2000-05-31 Zeneca Ltd Pyridine derivatives
GB9021571D0 (en) * 1990-10-04 1990-11-21 Ici Plc Heterocyclic acids
US5925795A (en) * 1996-09-16 1999-07-20 Zeneca Limited Processes for the preparation of aryl-β-diketones, arylpyrimidine ketones and crop protection intermediates
GB0413970D0 (en) * 2004-06-22 2004-07-28 Syngenta Participations Ag Chemical compounds
RU2449999C2 (ru) * 2006-01-18 2012-05-10 Эвольва Са Модуляторы ppar
WO2008089462A2 (en) * 2007-01-18 2008-07-24 Evolva Sa Substituted 1,3-dioxanes and their uses
WO2008089464A1 (en) * 2007-01-18 2008-07-24 Evolva Sa Prodrugs of substituted 1,3-dioxanes and their uses
JP6238970B2 (ja) * 2012-05-18 2017-11-29 サノフイ ベンゾ［１，３］ジオキシン誘導体およびｌｐａｒ５アンタゴニストとしてのその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4243592A (en) * 1979-03-12 1981-01-06 The Upjohn Company 9,11-Dideoxy-10-oxa-TXB compounds
GB8310407D0 (en) * 1982-05-12 1983-05-25 Ici Plc 1 3 - dioxan -5- ylalkenoic acids
GB8417314D0 (en) * 1984-07-06 1984-08-08 Ici Plc Carboxylic acid derivatives

Also Published As

Publication number Publication date
EP0094239A2 (en) 1983-11-16
EP0094239B1 (en) 1987-07-15
PL140463B1 (en) 1987-04-30
PT76684A (en) 1983-06-01
PL250098A1 (en) 1985-07-02
AR240817A1 (es) 1991-02-28
NO831679L (no) 1983-11-14
US5166377A (en) 1992-11-24
CS245795B2 (en) 1986-10-16
PH21691A (en) 1988-01-13
CA1269109A (en) 1990-05-15
MW1583A1 (en) 1985-02-13
PL140462B1 (en) 1987-04-30
HK17889A (en) 1989-03-10
DE3372483D1 (de) 1987-08-20
US4745198A (en) 1988-05-17
FI831664A0 (fi) 1983-05-12
EP0094239A3 (en) 1984-12-12
DK163431C (da) 1992-07-20
CA1268771A (en) 1990-05-08
DK163431B (da) 1992-03-02
ATE28329T1 (de) 1987-08-15
IL68628A0 (en) 1984-05-31
PL250099A1 (en) 1985-07-02
GB8310407D0 (en) 1983-05-25
HU198705B (en) 1989-11-28
CS333683A2 (en) 1985-09-17
KE3823A (en) 1988-10-21
NO162383B (no) 1989-09-11
AU1422383A (en) 1983-11-17
DD212515A5 (de) 1984-08-15
SU1277893A3 (ru) 1986-12-15
SG57088G (en) 1989-01-27
NZ204202A (en) 1986-05-09
CS725784A2 (en) 1985-09-17
JPS58222081A (ja) 1983-12-23
ES8608507A1 (es) 1986-06-16
JPH0378389B2 (en:Method) 1991-12-13
DD219769A5 (de) 1985-03-13
KR880002001B1 (ko) 1988-10-11
CA1268772A (en) 1990-05-08
ES528575A0 (es) 1986-10-16
ES528577A0 (es) 1986-06-16
FI80027C (fi) 1990-04-10
CY1453A (en) 1989-07-21
AU562056B2 (en) 1987-05-28
ES528576A0 (es) 1986-10-16
DK211883D0 (da) 1983-05-11
ZA833179B (en) 1984-04-25
GR78138B (en:Method) 1984-09-26
FI831664L (fi) 1983-11-13
ES8700250A1 (es) 1986-10-16
DK211883A (da) 1983-11-13
ES522331A0 (es) 1984-08-16
CS245783B2 (en) 1986-10-16
PT76684B (en) 1986-01-14
AR240817A2 (es) 1991-02-28
KR840004739A (ko) 1984-10-24
PL241920A1 (en) 1985-03-26
IE55114B1 (en) 1990-06-06
FI80027B (fi) 1989-12-29
US4567197A (en) 1986-01-28
ES8700249A1 (es) 1986-10-16
PL140274B1 (en) 1987-04-30
ES8407038A1 (es) 1984-08-16
ZW10083A1 (en) 1984-11-28
CA1258464A (en) 1989-08-15
IE831005L (en) 1983-11-12

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Legal Events

Date Code Title Description
MKEX Expiry