CA1224735A - Cloning system for kluyveromyces species - Google Patents
Cloning system for kluyveromyces speciesInfo
- Publication number
- CA1224735A CA1224735A CA000428497A CA428497A CA1224735A CA 1224735 A CA1224735 A CA 1224735A CA 000428497 A CA000428497 A CA 000428497A CA 428497 A CA428497 A CA 428497A CA 1224735 A CA1224735 A CA 1224735A
- Authority
- CA
- Canada
- Prior art keywords
- kluyveromyces
- yeast
- dna
- dna sequence
- yeast cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
- C07K14/43—Sweetening agents, e.g. thaumatin, monellin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- C12N15/68—Stabilisation of the vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6478—Aspartic endopeptidases (3.4.23)
- C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Botany (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8202091 | 1982-05-19 | ||
| NL8202091 | 1982-05-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1224735A true CA1224735A (en) | 1987-07-28 |
Family
ID=19839766
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000428497A Expired CA1224735A (en) | 1982-05-19 | 1983-05-19 | Cloning system for kluyveromyces species |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US4657857A (h) |
| EP (2) | EP0096430B2 (h) |
| JP (3) | JPS59501572A (h) |
| AR (1) | AR241796A1 (h) |
| AT (2) | ATE49421T1 (h) |
| AU (1) | AU571181B2 (h) |
| BR (1) | BR8307525A (h) |
| CA (1) | CA1224735A (h) |
| DE (2) | DE3381090D1 (h) |
| DK (1) | DK173699B1 (h) |
| ES (1) | ES522556A0 (h) |
| FI (1) | FI81379C (h) |
| GR (1) | GR78852B (h) |
| HU (1) | HU204097B (h) |
| IE (1) | IE55817B1 (h) |
| IL (1) | IL68733A (h) |
| NO (1) | NO172397C (h) |
| NZ (1) | NZ204302A (h) |
| PT (1) | PT76727B (h) |
| WO (2) | WO1983004051A1 (h) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58146281A (ja) * | 1981-10-19 | 1983-08-31 | Suntory Ltd | 酵母細胞の形質転換法 |
| WO1983004051A1 (en) * | 1982-05-19 | 1983-11-24 | Unilever N.V. | Expression of preprothaumatin-like proteins in kluyveromyces yeasts |
| US4943529A (en) | 1982-05-19 | 1990-07-24 | Gist-Brocades Nv | Kluyveromyces as a host strain |
| JPH0716432B2 (ja) * | 1982-10-20 | 1995-03-01 | サントリー株式会社 | 酵母の高発現ベクタープラスミドを用いたペプチドの生産方法 |
| US4876197A (en) * | 1983-02-22 | 1989-10-24 | Chiron Corporation | Eukaryotic regulatable transcription |
| CA1341302C (en) * | 1983-02-22 | 2001-10-09 | Rae Lyn Burke | Yeast expression systems with vectors having gapdh or pyk promoters and synthesis of foreign protein |
| DE3480006D1 (en) * | 1983-05-19 | 1989-11-09 | Unilever Nv | Improvements in the expression of newly introduced genes in yeast cells |
| AU577334B2 (en) * | 1983-10-11 | 1988-09-22 | International Genetic Engineering, Inc. | Synthetic thaumatin genes |
| IL75210A0 (en) * | 1984-05-22 | 1985-09-29 | Bioteknika International | Yeast vector |
| US5422267A (en) * | 1984-05-22 | 1995-06-06 | Robert R. Yocum | Industrial yeast comprising an integrated glucoamylase gene |
| US6214577B1 (en) | 1984-05-22 | 2001-04-10 | Robert Rogers Yocum | Yeast vectors conferring antibiotic resistance |
| US5240838A (en) * | 1984-07-27 | 1993-08-31 | Internationale Otrool Maatschappij "Octropa" B.V. | Regulatory sequences of alcohol oxidase (MOX) and dihydroxyacetonesynthase (DAS) of Hansenula polymorpha |
| US5741672A (en) * | 1984-07-27 | 1998-04-21 | Unilever Patent Holdings B.V. | Expression and production of polypeptides using the promoters of the hansenula polymorpha MOX and DAS genes |
| US4855231A (en) * | 1984-10-30 | 1989-08-08 | Phillips Petroleum Company | Regulatory region for heterologous gene expression in yeast |
| US4837148A (en) * | 1984-10-30 | 1989-06-06 | Phillips Petroleum Company | Autonomous replication sequences for yeast strains of the genus pichia |
| US4879231A (en) * | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| US5047340A (en) * | 1985-06-05 | 1991-09-10 | The University Of Kentucky Research Foundation | LAC+ saccharomyces cerevisiae |
| CA1310923C (en) * | 1985-11-13 | 1992-12-01 | Joachim Ludwig Weickmann | Dna encoding [asp --] and [lys -, asp --] thaumatin i |
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-
1983
- 1983-05-19 WO PCT/EP1983/000129 patent/WO1983004051A1/en unknown
- 1983-05-19 ES ES522556A patent/ES522556A0/es active Granted
- 1983-05-19 GR GR71403A patent/GR78852B/el unknown
- 1983-05-19 EP EP83200714A patent/EP0096430B2/en not_active Expired - Lifetime
- 1983-05-19 BR BR8307525A patent/BR8307525A/pt unknown
- 1983-05-19 AT AT83200714T patent/ATE49421T1/de not_active IP Right Cessation
- 1983-05-19 DE DE8383200714T patent/DE3381090D1/de not_active Expired - Lifetime
- 1983-05-19 PT PT76727A patent/PT76727B/pt unknown
- 1983-05-19 AU AU15539/83A patent/AU571181B2/en not_active Expired
- 1983-05-19 AR AR83293108A patent/AR241796A1/es active
- 1983-05-19 HU HU832272A patent/HU204097B/hu not_active IP Right Cessation
- 1983-05-19 EP EP83200712A patent/EP0096910B1/en not_active Expired
- 1983-05-19 JP JP58501746A patent/JPS59501572A/ja active Granted
- 1983-05-19 CA CA000428497A patent/CA1224735A/en not_active Expired
- 1983-05-19 AT AT83200712T patent/ATE42338T1/de not_active IP Right Cessation
- 1983-05-19 US US06/570,984 patent/US4657857A/en not_active Expired - Fee Related
- 1983-05-19 JP JP58501749A patent/JP2608540B2/ja not_active Expired - Lifetime
- 1983-05-19 DE DE8383200712T patent/DE3379665D1/de not_active Expired
- 1983-05-19 WO PCT/EP1983/000128 patent/WO1983004050A1/en active IP Right Grant
- 1983-05-19 IE IE1185/83A patent/IE55817B1/en not_active IP Right Cessation
- 1983-05-19 IL IL68733A patent/IL68733A/xx unknown
- 1983-05-20 NZ NZ204302A patent/NZ204302A/en unknown
-
1984
- 1984-01-11 DK DK198400113A patent/DK173699B1/da not_active IP Right Cessation
- 1984-01-13 NO NO84840133A patent/NO172397C/no not_active IP Right Cessation
- 1984-01-16 FI FI840149A patent/FI81379C/fi not_active IP Right Cessation
- 1984-01-19 US US06/572,414 patent/US4859596A/en not_active Expired - Lifetime
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1986
- 1986-02-26 JP JP61041331A patent/JPH0685720B2/ja not_active Expired - Lifetime
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