CA1197506A - Basically substituted 4-phenyl-4,5,6,7-tetrahydro- thieno[2,3-c]pyridines, processes for preparing them and pharmaceutical compositions containing them - Google Patents

Basically substituted 4-phenyl-4,5,6,7-tetrahydro- thieno[2,3-c]pyridines, processes for preparing them and pharmaceutical compositions containing them

Info

Publication number
CA1197506A
CA1197506A CA000422845A CA422845A CA1197506A CA 1197506 A CA1197506 A CA 1197506A CA 000422845 A CA000422845 A CA 000422845A CA 422845 A CA422845 A CA 422845A CA 1197506 A CA1197506 A CA 1197506A
Authority
CA
Canada
Prior art keywords
methyl
compound
group
pyridine
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000422845A
Other languages
English (en)
French (fr)
Inventor
Claus Schneider
Gerhard Walther
Karl-Heinz Weber
Wolf D. Bechtel
Karin Boke-Kuhn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Application granted granted Critical
Publication of CA1197506A publication Critical patent/CA1197506A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04B—TRANSMISSION
    • H04B17/00—Monitoring; Testing
    • H04B17/40—Monitoring; Testing of relay systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Signal Processing (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Manufacture Of Tobacco Products (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA000422845A 1982-03-05 1983-03-04 Basically substituted 4-phenyl-4,5,6,7-tetrahydro- thieno[2,3-c]pyridines, processes for preparing them and pharmaceutical compositions containing them Expired CA1197506A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3207939.7 1982-03-05
DE19823207939 DE3207939A1 (de) 1982-03-05 1982-03-05 Neue basisch substituierte 4-phenyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen

Publications (1)

Publication Number Publication Date
CA1197506A true CA1197506A (en) 1985-12-03

Family

ID=6157400

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000422845A Expired CA1197506A (en) 1982-03-05 1983-03-04 Basically substituted 4-phenyl-4,5,6,7-tetrahydro- thieno[2,3-c]pyridines, processes for preparing them and pharmaceutical compositions containing them

Country Status (24)

Country Link
US (2) US4482559A (en29)
EP (1) EP0088250B1 (en29)
JP (1) JPS58162591A (en29)
KR (1) KR840004110A (en29)
AT (1) ATE20066T1 (en29)
AU (1) AU554783B2 (en29)
CA (1) CA1197506A (en29)
CS (3) CS237342B2 (en29)
DD (1) DD210278A5 (en29)
DE (2) DE3207939A1 (en29)
DK (1) DK87383A (en29)
ES (3) ES520314A0 (en29)
FI (1) FI74282C (en29)
GB (1) GB2117762B (en29)
GR (1) GR78456B (en29)
HU (1) HU185193B (en29)
IL (1) IL68032A (en29)
NO (1) NO830758L (en29)
NZ (1) NZ203471A (en29)
PH (1) PH18897A (en29)
PL (3) PL139429B1 (en29)
PT (1) PT76335B (en29)
SU (1) SU1187723A3 (en29)
ZA (1) ZA831477B (en29)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2570701B1 (fr) * 1984-09-27 1987-05-22 Synthelabo Derives de furo(3,2-c)pyridines, leur preparation et leur application en therapeutique
JPS6210087A (ja) * 1985-07-03 1987-01-19 Shionogi & Co Ltd ４，７−ジヒドロチエノ〔２，３−ｂ〕ピリジン誘導体，その製造法および循環器系疾患治療剤
US4775757A (en) * 1986-09-22 1988-10-04 Ortho Pharmaceutical Corporation Thienopyridines useful as cardiovascular agents
US5532240A (en) * 1991-12-26 1996-07-02 Yoshitomi Pharmaceutical Industries, Ltd. Condensed thiophene compound and pharmaceutical use thereof
US6177443B1 (en) 1997-03-07 2001-01-23 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno[3, 2-C]pyridine derivatives, their preparation and use
WO1998040385A1 (en) * 1997-03-07 1998-09-17 Novo Nordisk A/S 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE
US6262044B1 (en) 1998-03-12 2001-07-17 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (PTPASES)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3823151A (en) * 1968-08-02 1974-07-09 Ciba Geigy Corp 4,5,6,7-tetrahydrothieno(2,3-d)pyridines
US3705910A (en) * 1970-05-20 1972-12-12 Exxon Research Engineering Co N-(2-(4,5,6,7-tetrahydrobenzothienyl))-propionamides
FR2358150A1 (fr) * 1976-07-13 1978-02-10 Parcor Nouvelles thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application
DE2746443C2 (de) * 1977-10-15 1986-09-18 C.H. Boehringer Sohn, 6507 Ingelheim 4-Phenyl-thieno-[2,3-c]-piperidine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
AT368504B (de) * 1977-10-15 1982-10-25 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer 4-phenyl-thieno- (2,3-c)-piperidine

Also Published As

Publication number Publication date
DE3363643D1 (en) 1986-07-03
HU185193B (en) 1984-12-28
ES525750A0 (es) 1984-06-01
FI74282C (fi) 1988-01-11
FI830661L (fi) 1983-09-06
ATE20066T1 (de) 1986-06-15
CS572083A2 (en) 1984-12-14
EP0088250A2 (de) 1983-09-14
GB8306033D0 (en) 1983-04-07
FI830661A0 (fi) 1983-03-01
ES8404357A1 (es) 1984-04-16
PL245746A1 (en) 1985-03-12
DK87383D0 (da) 1983-02-24
CS572183A2 (en) 1984-12-14
EP0088250B1 (de) 1986-05-28
DD210278A5 (de) 1984-06-06
CS237341B2 (en) 1985-07-16
US4550106A (en) 1985-10-29
FI74282B (fi) 1987-09-30
PH18897A (en) 1985-10-30
PL139429B1 (en) 1987-01-31
ZA831477B (en) 1984-11-28
PL240855A1 (en) 1984-06-18
PL138474B1 (en) 1986-09-30
DE3207939A1 (de) 1983-09-15
AU1205783A (en) 1983-09-08
ES8405406A1 (es) 1984-06-01
CS237342B2 (en) 1985-07-16
EP0088250A3 (en) 1984-04-25
PT76335B (de) 1986-02-03
US4482559A (en) 1984-11-13
JPS58162591A (ja) 1983-09-27
ES520314A0 (es) 1984-04-16
NZ203471A (en) 1985-05-31
DK87383A (da) 1983-09-06
KR840004110A (ko) 1984-10-06
GB2117762A (en) 1983-10-19
CS237337B2 (en) 1985-07-16
GB2117762B (en) 1985-09-25
PT76335A (de) 1983-04-01
SU1187723A3 (ru) 1985-10-23
NO830758L (no) 1983-09-06
ES525749A0 (es) 1984-06-01
ES8405405A1 (es) 1984-06-01
IL68032A (en) 1986-01-31
PL245747A1 (en) 1985-01-02
AU554783B2 (en) 1986-09-04
IL68032A0 (en) 1983-06-15
GR78456B (en29) 1983-03-04
PL137768B1 (en) 1986-07-31
CS137083A2 (en) 1984-12-14

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Legal Events

Date Code Title Description
MKEC Expiry (correction)
MKEX Expiry