CA1141379A - Derives geminaux dihalogenes de produits condenses de la pyrimidine-4-one; methode de preparation et compositions pharmaceutiques qui en renferment - Google Patents

Derives geminaux dihalogenes de produits condenses de la pyrimidine-4-one; methode de preparation et compositions pharmaceutiques qui en renferment

Info

Publication number
CA1141379A
CA1141379A CA000351662A CA351662A CA1141379A CA 1141379 A CA1141379 A CA 1141379A CA 000351662 A CA000351662 A CA 000351662A CA 351662 A CA351662 A CA 351662A CA 1141379 A CA1141379 A CA 1141379A
Authority
CA
Canada
Prior art keywords
tetrahydro
pyrimidine
oxo
pyrido
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000351662A
Other languages
English (en)
Inventor
Agnes Horvath
Tibor Breining
Lelle Vasvari (Nee Debreczy)
Istvan Hermecz
Zoltan Meszaros
Istvan Bitter
Jozsef Kokosi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Application granted granted Critical
Publication of CA1141379A publication Critical patent/CA1141379A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B62/00—Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
CA000351662A 1979-05-11 1980-05-09 Derives geminaux dihalogenes de produits condenses de la pyrimidine-4-one; methode de preparation et compositions pharmaceutiques qui en renferment Expired CA1141379A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUCI-1932 1979-05-11
HU79CI1932A HU179443B (en) 1979-05-11 1979-05-11 Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines

Publications (1)

Publication Number Publication Date
CA1141379A true CA1141379A (fr) 1983-02-15

Family

ID=10994747

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000351662A Expired CA1141379A (fr) 1979-05-11 1980-05-09 Derives geminaux dihalogenes de produits condenses de la pyrimidine-4-one; methode de preparation et compositions pharmaceutiques qui en renferment

Country Status (24)

Country Link
JP (1) JPS5615286A (fr)
AT (1) AT377261B (fr)
BE (1) BE883217A (fr)
CA (1) CA1141379A (fr)
CH (1) CH646971A5 (fr)
CS (1) CS241025B2 (fr)
DD (1) DD150605A5 (fr)
DE (1) DE3017564A1 (fr)
DK (1) DK204680A (fr)
ES (1) ES491896A0 (fr)
FI (1) FI68825C (fr)
FR (1) FR2456101A1 (fr)
GB (1) GB2051048B (fr)
GR (1) GR68518B (fr)
HU (1) HU179443B (fr)
IL (1) IL59967A (fr)
IT (1) IT1133085B (fr)
LU (1) LU82437A1 (fr)
NL (1) NL8002678A (fr)
NO (1) NO152607C (fr)
PL (1) PL124035B1 (fr)
PT (1) PT71213A (fr)
SE (1) SE441747B (fr)
SU (1) SU1151210A3 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178453B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydrazino-4-oxo-6,7,8,9-tetrahydro-4h-p-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
IL69274A (en) * 1982-08-05 1986-08-31 Erba Farmitalia (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
US5158952A (en) * 1988-11-07 1992-10-27 Janssen Pharmaceutica N.V. 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use
UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538494A (de) * 1966-11-02 1973-06-30 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung neuer Homopyrimidazol-Derivate
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Also Published As

Publication number Publication date
IL59967A (en) 1984-05-31
SU1151210A3 (ru) 1985-04-15
NO801378L (no) 1980-11-12
SE8003479L (sv) 1980-11-12
ES8102570A1 (es) 1981-02-16
PT71213A (en) 1980-06-01
BE883217A (fr) 1980-09-01
DD150605A5 (de) 1981-09-09
CS241025B2 (en) 1986-03-13
CS325880A2 (en) 1985-06-13
AT377261B (de) 1985-02-25
PL224163A1 (fr) 1981-02-13
IL59967A0 (en) 1980-07-31
HU179443B (en) 1982-10-28
FI68825B (fi) 1985-07-31
NL8002678A (nl) 1980-11-13
LU82437A1 (fr) 1980-07-31
GR68518B (fr) 1982-01-11
GB2051048A (en) 1981-01-14
GB2051048B (en) 1983-01-19
FR2456101A1 (fr) 1980-12-05
FI801512A (fi) 1980-11-12
IT1133085B (it) 1986-07-09
DK204680A (da) 1980-11-12
JPS5615286A (en) 1981-02-14
FI68825C (fi) 1985-11-11
CH646971A5 (de) 1984-12-28
SE441747B (sv) 1985-11-04
NO152607B (no) 1985-07-15
ES491896A0 (es) 1981-02-16
IT8067719A0 (it) 1980-05-09
DE3017564A1 (de) 1980-11-13
PL124035B1 (en) 1982-12-31
NO152607C (no) 1985-10-23
ATA247580A (de) 1984-07-15
FR2456101B1 (fr) 1985-04-05

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