CA1129419A - Monohydrated isophthalic acid picolylamide, process of preparation and pharmaceutical use thereof - Google Patents

Monohydrated isophthalic acid picolylamide, process of preparation and pharmaceutical use thereof

Info

Publication number
CA1129419A
CA1129419A CA375,430A CA375430A CA1129419A CA 1129419 A CA1129419 A CA 1129419A CA 375430 A CA375430 A CA 375430A CA 1129419 A CA1129419 A CA 1129419A
Authority
CA
Canada
Prior art keywords
picotamide
monohydrated
water
anhydrous
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA375,430A
Other languages
English (en)
French (fr)
Inventor
Giovanni Orzalesi
Ivo Volpato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Italo-Britannica L Manetti - H Roberts & C Soc
Original Assignee
Italo-Britannica L Manetti - H Roberts & C Soc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italo-Britannica L Manetti - H Roberts & C Soc filed Critical Italo-Britannica L Manetti - H Roberts & C Soc
Application granted granted Critical
Publication of CA1129419A publication Critical patent/CA1129419A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA375,430A 1980-04-23 1981-04-14 Monohydrated isophthalic acid picolylamide, process of preparation and pharmaceutical use thereof Expired CA1129419A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT48494/80A IT1143942B (it) 1980-04-23 1980-04-23 Picolilammide idrata di acido isoftalico ad azione antiaggregante piastrinica antitrombinica ed anticoagulante e procedimento per la sua preparazione
IT48494A80 1980-04-23

Publications (1)

Publication Number Publication Date
CA1129419A true CA1129419A (en) 1982-08-10

Family

ID=11266904

Family Applications (1)

Application Number Title Priority Date Filing Date
CA375,430A Expired CA1129419A (en) 1980-04-23 1981-04-14 Monohydrated isophthalic acid picolylamide, process of preparation and pharmaceutical use thereof

Country Status (23)

Country Link
JP (1) JPS6043063B2 (de)
AT (1) AT375645B (de)
AU (1) AU537921B2 (de)
BE (1) BE888528A (de)
CA (1) CA1129419A (de)
CH (1) CH649533A5 (de)
DD (1) DD158397A5 (de)
DE (1) DE3113150C2 (de)
DK (1) DK155735C (de)
ES (1) ES8203086A1 (de)
FI (1) FI74951C (de)
FR (1) FR2481283B1 (de)
GB (1) GB2080288B (de)
IE (1) IE51218B1 (de)
IL (1) IL62509A (de)
IT (1) IT1143942B (de)
NL (1) NL186860C (de)
NO (1) NO154193C (de)
NZ (1) NZ196677A (de)
OA (1) OA06795A (de)
PT (1) PT72899B (de)
SE (1) SE438674B (de)
ZA (1) ZA812362B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1214915B (it) * 1985-10-10 1990-01-31 Manetti & Roberts Italo Brit Derivato dell'acido 4-metossiisoftalico con attivita'farmacologica in disordini tromboembolici e procedimento per la sua preparazione
US5227492A (en) * 1988-01-20 1993-07-13 Yamanouchi Pharmaceutical Co., Ltd. Diurea derivatives useful as medicaments and processes for the preparation thereof
AR066696A1 (es) * 2007-05-21 2009-09-09 Dybly Ag Sales de picotamida. composiciones farmaceuticas.
CN111154114A (zh) * 2019-12-31 2020-05-15 肇庆学院 一种基于5-乙氧基间苯二甲酸的锌(ⅱ)金属有机配位化合物及其制备方法
CN111154113A (zh) * 2019-12-31 2020-05-15 肇庆学院 一种基于双核钴(ⅱ)的金属有机配合物及其制备方法
CN112159347B (zh) * 2020-10-27 2022-06-07 常州工程职业技术学院 吡考他胺的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL149810B (nl) * 1969-04-21 1976-06-15 Lilly Co Eli Werkwijze ter bereiding van een farmaceutisch preparaat door kristallijn cefalexine in een voor therapeutische toediening geschikte vorm te brengen, gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van voor bovengenoemde toepassing geschikt cefalexine.
IT1016005B (it) * 1970-07-01 1977-05-30 Manetti & Roberts Italo Brit Picolilamidi dell acido 4 idrossi isoftalico e suoi derivati e relativo procedimento di prepara zione
US3973026A (en) * 1975-02-05 1976-08-03 Societa Italo-Britannica L. Manetti-H. Roberts & C. Inhibitor of blood plate aggregation

Also Published As

Publication number Publication date
SE438674B (sv) 1985-04-29
ZA812362B (en) 1982-04-28
FI811257L (fi) 1981-10-24
AU537921B2 (en) 1984-07-19
ATA166481A (de) 1984-01-15
DE3113150A1 (de) 1982-01-28
SE8101963L (sv) 1981-10-24
NZ196677A (en) 1983-05-31
FI74951B (fi) 1987-12-31
AU6931081A (en) 1981-10-29
JPS5735566A (en) 1982-02-26
IE51218B1 (en) 1986-11-12
GB2080288A (en) 1982-02-03
JPS6043063B2 (ja) 1985-09-26
ES501470A0 (es) 1982-02-16
IL62509A0 (en) 1981-05-20
OA06795A (fr) 1982-12-31
GB2080288B (en) 1984-02-01
FR2481283B1 (de) 1985-01-04
DD158397A5 (de) 1983-01-12
NO811360L (no) 1981-10-26
DE3113150C2 (de) 1985-05-15
IT1143942B (it) 1986-10-29
NL8102016A (nl) 1981-11-16
NO154193B (no) 1986-04-28
ES8203086A1 (es) 1982-02-16
DK155735C (da) 1989-10-02
NL186860C (nl) 1991-03-18
AT375645B (de) 1984-08-27
IE810808L (en) 1981-10-23
FR2481283A1 (de) 1981-10-30
PT72899A (en) 1981-05-01
CH649533A5 (it) 1985-05-31
NO154193C (no) 1986-08-06
DK177281A (da) 1981-10-24
DK155735B (da) 1989-05-08
IT8048494A0 (it) 1980-04-23
FI74951C (fi) 1988-04-11
PT72899B (en) 1982-04-05
IL62509A (en) 1984-03-30
BE888528A (nl) 1981-08-17
NL186860B (nl) 1990-10-16

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Legal Events

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