CA1115701A - Alkoxyphenylpyrrolidones iii, processes for their manufacture and their use - Google Patents

Alkoxyphenylpyrrolidones iii, processes for their manufacture and their use

Info

Publication number
CA1115701A
CA1115701A CA332,897A CA332897A CA1115701A CA 1115701 A CA1115701 A CA 1115701A CA 332897 A CA332897 A CA 332897A CA 1115701 A CA1115701 A CA 1115701A
Authority
CA
Canada
Prior art keywords
pyrrolidone
phenyl
methoxyphenyl
methoxy
produced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA332,897A
Other languages
English (en)
French (fr)
Inventor
Dieter Seidelmann
Ralph Schmiechen
Gert Paschelke
Bernd Muller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of CA1115701A publication Critical patent/CA1115701A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
CA332,897A 1978-08-01 1979-07-31 Alkoxyphenylpyrrolidones iii, processes for their manufacture and their use Expired CA1115701A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP2834114.2 1978-08-01
DE19782834114 DE2834114A1 (de) 1978-08-01 1978-08-01 Polyalkoxyphenylpyrrolidone iii, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
CA1115701A true CA1115701A (en) 1982-01-05

Family

ID=6046151

Family Applications (1)

Application Number Title Priority Date Filing Date
CA332,897A Expired CA1115701A (en) 1978-08-01 1979-07-31 Alkoxyphenylpyrrolidones iii, processes for their manufacture and their use

Country Status (15)

Country Link
US (1) US4219551A (en:Method)
EP (1) EP0008645B1 (en:Method)
JP (1) JPS5522686A (en:Method)
AT (1) ATE9221T1 (en:Method)
AU (1) AU533442B2 (en:Method)
CA (1) CA1115701A (en:Method)
CS (1) CS225816B2 (en:Method)
DD (1) DD145104B3 (en:Method)
DE (2) DE2834114A1 (en:Method)
DK (1) DK152426C (en:Method)
ES (1) ES482917A1 (en:Method)
HU (1) HU183103B (en:Method)
IE (1) IE48915B1 (en:Method)
IL (1) IL57926A (en:Method)
SU (1) SU878197A3 (en:Method)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3424685A1 (de) * 1984-07-05 1986-02-06 Beiersdorf Ag, 2000 Hamburg Neue substituierte phenylpiperazinyl-propanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
SE8500573D0 (sv) * 1985-02-08 1985-02-08 Ferrosan Ab Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain
EP0288575A4 (en) * 1986-10-27 1990-10-10 Yoshitomi Pharmaceutical Industries, Ltd. Piperazine compounds and their medicinal use
DE3809031A1 (de) * 1988-03-15 1989-09-28 Schering Ag Neues mittel gegen obstruktive blasenentleerungsstoerung
DE3921593A1 (de) * 1989-06-28 1991-01-10 Schering Ag Verfahren zur racemattrennung von 4-aryl-2-oxo-pyrrolidin-3-carbonsaeure-ester
KR970702276A (ko) * 1994-04-22 1997-05-13 고오사이 아끼오 에테르 화합물 및 그의 용도(ether compound and use thereof)
DE19648011A1 (de) * 1996-11-20 1998-05-28 Bayer Ag Cyclische Imine
JP2004537554A (ja) * 2001-07-19 2004-12-16 シーブイ・セラピューティクス・インコーポレイテッド 置換されたピペラジン化合物および脂肪酸酸化インヒビターとしてのその使用
CA2463469A1 (en) * 2001-10-16 2003-04-24 Memory Pharmaceuticals Corporation 4-(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidone derivatives as pde-4 inhibitors for the treatment of neurological syndromes
RU2005135330A (ru) * 2003-04-16 2006-06-27 Мемори Фармасьютиклз Корпорейшн (Us) Ингибиторы фосфодиэстеразы 4
SG168409A1 (en) * 2003-04-18 2011-02-28 Memory Pharm Corp Pyrazole derivatives as phosphodiesterase 4 inhibitors
WO2006044528A1 (en) 2004-10-15 2006-04-27 Memory Pharmaceuticals Corporation Pyrazole derivatives as phosphodiesterase 4 inhibitors
CA2584328A1 (en) * 2004-10-20 2006-04-27 Memory Pharmaceuticals Corporation Phosphodiesterase 4 inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3577415A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-substituted phenoxypyrrolidines
DE2263211A1 (de) * 1972-12-23 1974-07-04 Boehringer Sohn Ingelheim Neue arylpiperazine und verfahren zu ihrer herstellung
DE2337461A1 (de) * 1973-07-24 1975-02-06 Boehringer Mannheim Gmbh Neue indolderivate und verfahren zu deren herstellung
US4120969A (en) * 1975-09-23 1978-10-17 A. H. Robins Company, Incorporated Heterocyclic analgetic and antidiarrheal compounds
DE2737630A1 (de) * 1977-08-20 1979-03-01 Boehringer Mannheim Gmbh Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4096331A (en) * 1976-12-28 1978-06-20 A. H. Robins Company, Incorporated 1-Substituted-3-aminoethoxypyrrolidines

Also Published As

Publication number Publication date
HU183103B (en) 1984-04-28
EP0008645B1 (de) 1984-09-05
DK323179A (da) 1980-02-02
DD145104A5 (de) 1980-11-19
JPS5522686A (en) 1980-02-18
IE48915B1 (en) 1985-06-12
IL57926A (en) 1983-10-31
SU878197A3 (ru) 1981-10-30
DK152426C (da) 1988-08-29
IE791453L (en) 1980-02-01
IL57926A0 (en) 1979-11-30
ES482917A1 (es) 1980-04-16
ATE9221T1 (de) 1984-09-15
EP0008645A1 (de) 1980-03-19
DD145104B3 (de) 1990-07-18
JPH0371423B2 (en:Method) 1991-11-13
CS225816B2 (en) 1984-02-13
DE2834114A1 (de) 1980-02-14
AU4944079A (en) 1980-02-07
AU533442B2 (en) 1983-11-24
US4219551A (en) 1980-08-26
DK152426B (da) 1988-02-29
DE2967204D1 (en) 1984-10-11

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Legal Events

Date Code Title Description
MKEX Expiry