IL57926A - Alkoxyphenylpyrrolidones,processes for their manufacture and pharmaceutical compositions containing the same - Google Patents
Alkoxyphenylpyrrolidones,processes for their manufacture and pharmaceutical compositions containing the sameInfo
- Publication number
- IL57926A IL57926A IL57926A IL5792679A IL57926A IL 57926 A IL57926 A IL 57926A IL 57926 A IL57926 A IL 57926A IL 5792679 A IL5792679 A IL 5792679A IL 57926 A IL57926 A IL 57926A
- Authority
- IL
- Israel
- Prior art keywords
- alkoxyphenylpyrrolidones
- manufacture
- processes
- same
- pharmaceutical compositions
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000006274 (C1-C3)alkoxy group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782834114 DE2834114A1 (de) | 1978-08-01 | 1978-08-01 | Polyalkoxyphenylpyrrolidone iii, verfahren zu ihrer herstellung und ihre verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL57926A0 IL57926A0 (en) | 1979-11-30 |
| IL57926A true IL57926A (en) | 1983-10-31 |
Family
ID=6046151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL57926A IL57926A (en) | 1978-08-01 | 1979-07-31 | Alkoxyphenylpyrrolidones,processes for their manufacture and pharmaceutical compositions containing the same |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4219551A (xx) |
| EP (1) | EP0008645B1 (xx) |
| JP (1) | JPS5522686A (xx) |
| AT (1) | ATE9221T1 (xx) |
| AU (1) | AU533442B2 (xx) |
| CA (1) | CA1115701A (xx) |
| CS (1) | CS225816B2 (xx) |
| DD (1) | DD145104B3 (xx) |
| DE (2) | DE2834114A1 (xx) |
| DK (1) | DK152426C (xx) |
| ES (1) | ES482917A1 (xx) |
| HU (1) | HU183103B (xx) |
| IE (1) | IE48915B1 (xx) |
| IL (1) | IL57926A (xx) |
| SU (1) | SU878197A3 (xx) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3424685A1 (de) * | 1984-07-05 | 1986-02-06 | Beiersdorf Ag, 2000 Hamburg | Neue substituierte phenylpiperazinyl-propanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen |
| SE8500573D0 (sv) * | 1985-02-08 | 1985-02-08 | Ferrosan Ab | Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain |
| JPH0788357B2 (ja) * | 1986-10-27 | 1995-09-27 | 吉富製薬株式会社 | ピペラジン化合物 |
| DE3809031A1 (de) * | 1988-03-15 | 1989-09-28 | Schering Ag | Neues mittel gegen obstruktive blasenentleerungsstoerung |
| DD295358A5 (de) * | 1989-06-28 | 1991-10-31 | �����@������������������k�� | Verfahren zur racemattrennung von 4-aryl-2-oxo-pyrrolidin-3-carbonsaeure-estern |
| DE19648011A1 (de) * | 1996-11-20 | 1998-05-28 | Bayer Ag | Cyclische Imine |
| PT1406898E (pt) * | 2001-07-19 | 2005-08-31 | Cv Therapeutics Inc | Compostos de piperazina substituida e sua utilizacao como inibidores de oxidacao de acidos gordos |
| DE60233884D1 (de) * | 2001-10-16 | 2009-11-12 | Memory Pharmaceutical Corp | 4(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidon-derivate als pde-4-hemmer zur behandlung von neurologischen syndromen |
| SG169900A1 (en) * | 2003-04-16 | 2011-04-29 | Memory Pharm Corp | 4 - (3,4 - disubstituted phenyl) - pyrrolidin-2-one compounds as phosphodiesterase 4 inhibitors |
| CN1809559B (zh) * | 2003-04-18 | 2010-06-02 | 记忆药物公司 | 作为磷酸二酯酶4抑制剂的吡唑衍生物 |
| CA2584317A1 (en) * | 2004-10-15 | 2006-04-27 | Memory Pharmaceuticals Corporation | Pyrazole derivatives as phosphodiesterase 4 inhibitors |
| US7585882B2 (en) * | 2004-10-20 | 2009-09-08 | Memory Pharmaceuticals Corporation | Phosphodiesterase 4 inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3577415A (en) * | 1968-12-23 | 1971-05-04 | Robins Co Inc A H | 1-substituted-3-substituted phenoxypyrrolidines |
| DE2263211A1 (de) * | 1972-12-23 | 1974-07-04 | Boehringer Sohn Ingelheim | Neue arylpiperazine und verfahren zu ihrer herstellung |
| DE2337461A1 (de) * | 1973-07-24 | 1975-02-06 | Boehringer Mannheim Gmbh | Neue indolderivate und verfahren zu deren herstellung |
| US4120969A (en) * | 1975-09-23 | 1978-10-17 | A. H. Robins Company, Incorporated | Heterocyclic analgetic and antidiarrheal compounds |
| DE2737630A1 (de) * | 1977-08-20 | 1979-03-01 | Boehringer Mannheim Gmbh | Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US4096331A (en) * | 1976-12-28 | 1978-06-20 | A. H. Robins Company, Incorporated | 1-Substituted-3-aminoethoxypyrrolidines |
-
1978
- 1978-08-01 DE DE19782834114 patent/DE2834114A1/de not_active Withdrawn
-
1979
- 1979-07-18 AT AT79102507T patent/ATE9221T1/de not_active IP Right Cessation
- 1979-07-18 EP EP79102507A patent/EP0008645B1/de not_active Expired
- 1979-07-18 DE DE7979102507T patent/DE2967204D1/de not_active Expired
- 1979-07-27 ES ES482917A patent/ES482917A1/es not_active Expired
- 1979-07-27 DD DD79214657A patent/DD145104B3/de unknown
- 1979-07-31 CA CA332,897A patent/CA1115701A/en not_active Expired
- 1979-07-31 DK DK323179A patent/DK152426C/da not_active IP Right Cessation
- 1979-07-31 IL IL57926A patent/IL57926A/xx unknown
- 1979-07-31 HU HU79SCHE685A patent/HU183103B/hu not_active IP Right Cessation
- 1979-07-31 SU SU792791951A patent/SU878197A3/ru active
- 1979-08-01 AU AU49440/79A patent/AU533442B2/en not_active Ceased
- 1979-08-01 US US06/062,865 patent/US4219551A/en not_active Expired - Lifetime
- 1979-08-01 JP JP9742379A patent/JPS5522686A/ja active Granted
- 1979-08-01 CS CS795308A patent/CS225816B2/cs unknown
- 1979-08-08 IE IE1453/79A patent/IE48915B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU4944079A (en) | 1980-02-07 |
| US4219551A (en) | 1980-08-26 |
| JPH0371423B2 (xx) | 1991-11-13 |
| SU878197A3 (ru) | 1981-10-30 |
| DK152426C (da) | 1988-08-29 |
| ES482917A1 (es) | 1980-04-16 |
| JPS5522686A (en) | 1980-02-18 |
| CA1115701A (en) | 1982-01-05 |
| DD145104B3 (de) | 1990-07-18 |
| DK323179A (da) | 1980-02-02 |
| DE2834114A1 (de) | 1980-02-14 |
| EP0008645A1 (de) | 1980-03-19 |
| DK152426B (da) | 1988-02-29 |
| AU533442B2 (en) | 1983-11-24 |
| DD145104A5 (de) | 1980-11-19 |
| CS225816B2 (en) | 1984-02-13 |
| IE791453L (en) | 1980-02-01 |
| DE2967204D1 (en) | 1984-10-11 |
| HU183103B (en) | 1984-04-28 |
| IL57926A0 (en) | 1979-11-30 |
| IE48915B1 (en) | 1985-06-12 |
| ATE9221T1 (de) | 1984-09-15 |
| EP0008645B1 (de) | 1984-09-05 |
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