CA1105454A - PREPARATION OF 1-N-¬.omega.-AMINO-.alpha.- HYDROXYALKANOYL| AMINOGLYCOSIDE ANTIBIOTICS - Google Patents

PREPARATION OF 1-N-¬.omega.-AMINO-.alpha.- HYDROXYALKANOYL| AMINOGLYCOSIDE ANTIBIOTICS

Info

Publication number
CA1105454A
CA1105454A CA301,968A CA301968A CA1105454A CA 1105454 A CA1105454 A CA 1105454A CA 301968 A CA301968 A CA 301968A CA 1105454 A CA1105454 A CA 1105454A
Authority
CA
Canada
Prior art keywords
acid
amino
formula xiii
acylating derivative
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA301,968A
Other languages
English (en)
French (fr)
Inventor
John G. Keil
Jeng S. Lin
Martin J. Cron
Mariano V. Ruggeri
Derek Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Priority to CA370,572A priority Critical patent/CA1105452A/en
Application granted granted Critical
Publication of CA1105454A publication Critical patent/CA1105454A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA301,968A 1977-04-28 1978-04-25 PREPARATION OF 1-N-¬.omega.-AMINO-.alpha.- HYDROXYALKANOYL| AMINOGLYCOSIDE ANTIBIOTICS Expired CA1105454A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA370,572A CA1105452A (en) 1977-04-28 1981-02-10 PREPARATION OF 1-N-[.omega.-AMINO-.alpha.- HYDROXYALKANOYL]AMINOGLYCOSIDE ANTIBIOTICS

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US79180677A 1977-04-28 1977-04-28
US791,806 1977-04-28
US88858578A 1978-03-20 1978-03-20
US888,585 1978-03-20

Publications (1)

Publication Number Publication Date
CA1105454A true CA1105454A (en) 1981-07-21

Family

ID=27121201

Family Applications (2)

Application Number Title Priority Date Filing Date
CA301,962A Expired CA1100953A (en) 1977-04-28 1978-04-25 PREPARATION OF 1-N¬.omega.-AMINO-.alpha.-HYDROXYALKANOYL| KANAMYCINS
CA301,968A Expired CA1105454A (en) 1977-04-28 1978-04-25 PREPARATION OF 1-N-¬.omega.-AMINO-.alpha.- HYDROXYALKANOYL| AMINOGLYCOSIDE ANTIBIOTICS

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA301,962A Expired CA1100953A (en) 1977-04-28 1978-04-25 PREPARATION OF 1-N¬.omega.-AMINO-.alpha.-HYDROXYALKANOYL| KANAMYCINS

Country Status (27)

Country Link
JP (1) JPS53149951A (xx)
AR (1) AR218910A1 (xx)
AT (1) AT357675B (xx)
CA (2) CA1100953A (xx)
CH (1) CH639104A5 (xx)
CS (1) CS207607B2 (xx)
CY (1) CY1241A (xx)
DE (2) DE2818822A1 (xx)
DK (2) DK165450C (xx)
EG (1) EG13710A (xx)
ES (1) ES469303A1 (xx)
FI (1) FI781288A (xx)
FR (2) FR2388826A1 (xx)
GB (1) GB1598294A (xx)
HK (1) HK51484A (xx)
IE (2) IE46945B1 (xx)
IT (2) IT1156718B (xx)
KE (1) KE3398A (xx)
LU (1) LU79541A1 (xx)
MY (1) MY8500528A (xx)
NL (1) NL178790C (xx)
NO (2) NO149635C (xx)
PL (1) PL117307B1 (xx)
PT (1) PT67959B (xx)
SE (2) SE447259B (xx)
SG (1) SG22884G (xx)
YU (2) YU102578A (xx)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8383596B2 (en) 2007-11-21 2013-02-26 Achaogen, Inc. Antibacterial aminoglycoside analogs
US8492354B2 (en) 2009-05-15 2013-07-23 Achaogen, Inc. Antibacterial aminoglycoside analogs
US8524675B2 (en) 2009-05-15 2013-09-03 Achaogen, Inc. Antibacterial aminoglycoside analogs
US8524689B2 (en) 2009-05-15 2013-09-03 Achaogen, Inc. Antibacterial aminoglycoside analogs
US8653042B2 (en) 2009-05-15 2014-02-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
US8658606B2 (en) 2009-05-15 2014-02-25 Achaogen, Inc. Antibacterial aminoglycoside analogs

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55306A (en) * 1978-04-28 1980-01-05 Bristol Myers Co Manufacture of 11nn*omegaaaminooalphaahydroxy alkanoyl**aminoglycoside antibiotic
TW200303209A (en) * 2002-02-19 2003-09-01 Amato Pharm Prod Ltd Lactic acid derivative

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8383596B2 (en) 2007-11-21 2013-02-26 Achaogen, Inc. Antibacterial aminoglycoside analogs
US8822424B2 (en) 2007-11-21 2014-09-02 Achaogen, Inc. Antibacterial aminoglycoside analogs
US9266919B2 (en) 2007-11-21 2016-02-23 Achaogen, Inc. Antibacterial aminoglycoside analogs
US9688711B2 (en) 2007-11-21 2017-06-27 Achaogen, Inc. Antibacterial aminoglycoside analogs
US11117915B2 (en) 2007-11-21 2021-09-14 Cipla USA, Inc. Antibacterial aminoglycoside analogs
US8492354B2 (en) 2009-05-15 2013-07-23 Achaogen, Inc. Antibacterial aminoglycoside analogs
US8524675B2 (en) 2009-05-15 2013-09-03 Achaogen, Inc. Antibacterial aminoglycoside analogs
US8524689B2 (en) 2009-05-15 2013-09-03 Achaogen, Inc. Antibacterial aminoglycoside analogs
US8653042B2 (en) 2009-05-15 2014-02-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
US8658606B2 (en) 2009-05-15 2014-02-25 Achaogen, Inc. Antibacterial aminoglycoside analogs
USRE47741E1 (en) 2009-05-15 2019-11-26 Achaogen, Inc. Antibacterial aminoglycoside analogs

Also Published As

Publication number Publication date
SE447259B (sv) 1986-11-03
DE2818822C2 (xx) 1989-01-26
NO154697B (no) 1986-08-25
IT7849137A0 (it) 1978-04-28
FR2388827A1 (fr) 1978-11-24
DK172543B1 (da) 1998-12-07
AT357675B (de) 1980-07-25
NL178790C (nl) 1986-05-16
IE47271B1 (en) 1984-02-08
YU102478A (en) 1982-10-31
DK183078A (da) 1978-10-29
NL7804503A (nl) 1978-10-31
DK165450C (da) 1993-04-13
MY8500528A (en) 1985-12-31
FR2388826B1 (xx) 1982-12-10
JPS53149951A (en) 1978-12-27
SE7804973L (sv) 1978-10-29
GB1598294A (en) 1981-09-16
NL178790B (nl) 1985-12-16
IE46945B1 (en) 1983-11-16
NO831197L (no) 1978-10-31
IE780842L (en) 1978-10-28
JPS5721277B2 (xx) 1982-05-06
NO154697C (no) 1986-12-03
SG22884G (en) 1985-01-04
CA1100953A (en) 1981-05-12
SE461148B (sv) 1990-01-15
NO149635C (no) 1984-05-23
CH639104A5 (en) 1983-10-31
ATA312778A (de) 1979-12-15
FR2388826A1 (fr) 1978-11-24
CS207607B2 (en) 1981-08-31
LU79541A1 (fr) 1978-11-28
DE2818992A1 (de) 1978-11-23
DE2818822A1 (de) 1978-11-09
KE3398A (en) 1984-06-08
IE780841L (en) 1978-10-28
PT67959A (en) 1978-05-01
ES469303A1 (es) 1979-09-16
DE2818992C2 (xx) 1988-03-17
NO781437L (no) 1978-10-31
FR2388827B1 (xx) 1982-07-09
PT67959B (en) 1980-03-05
SE8305538D0 (sv) 1983-10-07
IT1105500B (it) 1985-11-04
EG13710A (en) 1982-09-30
NO149635B (no) 1984-02-13
YU41590B (en) 1987-12-31
HK51484A (en) 1984-06-22
DK165450B (da) 1992-11-30
DK182978A (da) 1978-10-29
IT1156718B (it) 1987-02-04
SE8305538L (sv) 1983-10-07
PL206457A1 (xx) 1980-03-24
PL117307B1 (en) 1981-07-31
YU102578A (en) 1983-01-21
AR218910A1 (es) 1980-07-15
FI781288A (fi) 1978-10-29
CY1241A (en) 1984-06-29
IT7849136A0 (it) 1978-04-28

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