BRPI0811548A2 - Forma polimórfica de um composto, composição farmacêutica, e, processo para sintetizar uma forma polimórfica de um composto - Google Patents

Forma polimórfica de um composto, composição farmacêutica, e, processo para sintetizar uma forma polimórfica de um composto

Info

Publication number
BRPI0811548A2
BRPI0811548A2 BRPI0811548-6A2A BRPI0811548A BRPI0811548A2 BR PI0811548 A2 BRPI0811548 A2 BR PI0811548A2 BR PI0811548 A BRPI0811548 A BR PI0811548A BR PI0811548 A2 BRPI0811548 A2 BR PI0811548A2
Authority
BR
Brazil
Prior art keywords
compound
polymorphic form
synthesize
pharmaceutical composition
polymorphic
Prior art date
Application number
BRPI0811548-6A2A
Other languages
English (en)
Portuguese (pt)
Inventor
Alexander Charles Weymouth-Wilson
Shabana Ahmed
Mark William Hooper
Karen June Etherington
Original Assignee
Summit Corp Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Summit Corp Plc filed Critical Summit Corp Plc
Publication of BRPI0811548A2 publication Critical patent/BRPI0811548A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D263/57—Aryl or substituted aryl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BRPI0811548-6A2A 2007-08-15 2008-08-14 Forma polimórfica de um composto, composição farmacêutica, e, processo para sintetizar uma forma polimórfica de um composto BRPI0811548A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0715937.9A GB0715937D0 (en) 2007-08-15 2007-08-15 Method of treatment og duchenne muscular dystrophy
PCT/EP2008/006718 WO2009021748A2 (en) 2007-08-15 2008-08-14 Polymorphs of a compound for the treatment of duchenne muscular dystrophy

Publications (1)

Publication Number Publication Date
BRPI0811548A2 true BRPI0811548A2 (pt) 2014-11-18

Family

ID=38566447

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0811548-6A2A BRPI0811548A2 (pt) 2007-08-15 2008-08-14 Forma polimórfica de um composto, composição farmacêutica, e, processo para sintetizar uma forma polimórfica de um composto
BRPI0811315-7A2A BRPI0811315A2 (pt) 2007-08-15 2008-08-14 Processo para a preparação de um composto

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0811315-7A2A BRPI0811315A2 (pt) 2007-08-15 2008-08-14 Processo para a preparação de um composto

Country Status (17)

Country Link
US (2) US20090048314A1 (enExample)
EP (2) EP2176246A2 (enExample)
JP (2) JP2010535829A (enExample)
KR (1) KR20100075777A (enExample)
CN (2) CN101896475A (enExample)
AR (1) AR068810A1 (enExample)
AU (2) AU2008286324A1 (enExample)
BR (2) BRPI0811548A2 (enExample)
CA (2) CA2685939A1 (enExample)
CL (1) CL2008002391A1 (enExample)
GB (1) GB0715937D0 (enExample)
IL (1) IL201908A0 (enExample)
MX (2) MX2009011916A (enExample)
PE (1) PE20090604A1 (enExample)
RU (1) RU2009141831A (enExample)
TW (1) TW200911767A (enExample)
WO (2) WO2009021748A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1986633B1 (en) * 2006-02-10 2014-07-30 Summit Corporation Plc Treatment of duchenne muscular dystrophy
GB201208178D0 (en) 2012-05-10 2012-06-20 Summit Corp Plc Pharmaceutical composition for the treatment of duchenne muscular dystrophy
GB201412010D0 (en) 2014-07-04 2014-08-20 Summit Corp Plc Treatment of hypertransaminasemia
KR20190026647A (ko) 2016-03-30 2019-03-13 서밋 (옥스포드) 리미티드 뒤쉔 근육 영양장애의 치료용 조성물
WO2017175842A1 (ja) * 2016-04-07 2017-10-12 国立大学法人京都大学 スプライシングの改変に関する化合物及び医薬組成物
KR102019048B1 (ko) 2017-02-06 2019-09-09 가톨릭대학교 산학협력단 MG53과 Orai1의 결합을 이용한 근육긴장저하 치료제 스크리닝 방법
KR101886788B1 (ko) 2017-02-07 2018-08-09 가톨릭대학교 산학협력단 MG53과 Orai1의 결합을 이용한 뒤시엔느 골격근 위축증 치료제 스크리닝 방법
EP4403171A3 (en) 2017-06-19 2024-09-11 University of Maryland, Baltimore Microtubule polymerization inhibitor prodrugs and methods of using the same

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Also Published As

Publication number Publication date
US20090048314A1 (en) 2009-02-19
JP2010535829A (ja) 2010-11-25
AU2008286324A1 (en) 2009-02-19
GB0715937D0 (en) 2007-09-26
AR068810A1 (es) 2009-12-09
CL2008002391A1 (es) 2009-05-22
CN101896475A (zh) 2010-11-24
AU2008286325A1 (en) 2009-02-19
EP2188270A2 (en) 2010-05-26
PE20090604A1 (es) 2009-05-16
RU2009141831A (ru) 2011-05-20
BRPI0811315A2 (pt) 2015-01-27
WO2009021748A2 (en) 2009-02-19
MX2009011967A (es) 2009-11-19
WO2009021749A8 (en) 2009-09-11
WO2009021749A3 (en) 2009-04-02
EP2176246A2 (en) 2010-04-21
JP2010535830A (ja) 2010-11-25
KR20100075777A (ko) 2010-07-05
US20100267961A1 (en) 2010-10-21
WO2009021748A3 (en) 2009-04-02
CA2685590A1 (en) 2009-02-19
CA2685939A1 (en) 2009-02-19
CN101679323A (zh) 2010-03-24
US8138351B2 (en) 2012-03-20
WO2009021749A2 (en) 2009-02-19
TW200911767A (en) 2009-03-16
MX2009011916A (es) 2009-11-18
IL201908A0 (en) 2010-06-16

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: BIOMARIN IGA LIMITED (BS)

B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]