PT2242515E - Processo para produzir uma formulação farmacêutica de agentes de contraste - Google Patents

Processo para produzir uma formulação farmacêutica de agentes de contraste Download PDF

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Publication number
PT2242515E
PT2242515E PT97124036T PT09712403T PT2242515E PT 2242515 E PT2242515 E PT 2242515E PT 97124036 T PT97124036 T PT 97124036T PT 09712403 T PT09712403 T PT 09712403T PT 2242515 E PT2242515 E PT 2242515E
Authority
PT
Portugal
Prior art keywords
preparing
pharmaceutical formulation
contrast agents
agents
contrast
Prior art date
Application number
PT97124036T
Other languages
English (en)
Inventor
Marc Port
Claire Corot
Dominique Meyer
Vincent Barbotin
Bruno Bonnemain
Original Assignee
Guerbet Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40955314&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2242515(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR0851055A external-priority patent/FR2927539B1/fr
Application filed by Guerbet Sa filed Critical Guerbet Sa
Publication of PT2242515E publication Critical patent/PT2242515E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • A61K49/108—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA the metal complex being Gd-DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT97124036T 2008-02-19 2009-02-18 Processo para produzir uma formulação farmacêutica de agentes de contraste PT2242515E (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0851055A FR2927539B1 (fr) 2008-02-19 2008-02-19 Procede de preparation d'une formulation pharmaceutique d'agents de contraste.
EP08154745 2008-04-17
US12/155,997 US20090208421A1 (en) 2008-02-19 2008-06-12 Process for preparing a pharmaceutical formulation of contrast agents

Publications (1)

Publication Number Publication Date
PT2242515E true PT2242515E (pt) 2014-07-11

Family

ID=40955314

Family Applications (3)

Application Number Title Priority Date Filing Date
PT141650069T PT2799089T (pt) 2008-02-19 2009-02-18 Processo para produzir uma formulação farmacêutica de agentes de contraste
PT97124036T PT2242515E (pt) 2008-02-19 2009-02-18 Processo para produzir uma formulação farmacêutica de agentes de contraste
PT141650085T PT2799090T (pt) 2008-02-19 2009-02-18 Processo para produzir uma formulação farmacêutica de agentes de contraste

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT141650069T PT2799089T (pt) 2008-02-19 2009-02-18 Processo para produzir uma formulação farmacêutica de agentes de contraste

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT141650085T PT2799090T (pt) 2008-02-19 2009-02-18 Processo para produzir uma formulação farmacêutica de agentes de contraste

Country Status (17)

Country Link
US (6) US20090208421A1 (pt)
EP (6) EP2799089B9 (pt)
JP (3) JP5469615B2 (pt)
KR (1) KR101063060B1 (pt)
CN (1) CN101977633B (pt)
BR (1) BRPI0908221B1 (pt)
CA (1) CA2714118C (pt)
CY (2) CY1115259T1 (pt)
DE (1) DE202008010019U1 (pt)
DK (3) DK2242515T3 (pt)
ES (3) ES2593127T5 (pt)
HR (2) HRP20140537T1 (pt)
HU (2) HUE031091T2 (pt)
LT (2) LT2799089T (pt)
PL (3) PL2242515T3 (pt)
PT (3) PT2799089T (pt)
WO (1) WO2009103744A2 (pt)

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RU2019139432A (ru) 2017-05-05 2021-06-07 Сентр фор Проуб Девелопмент энд Коммерсиализэйшн Фармакокинетическая оптимизация бифункциональных хелатов и их применение
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Also Published As

Publication number Publication date
US20090208421A1 (en) 2009-08-20
EP2799089B9 (en) 2017-09-06
US9907866B2 (en) 2018-03-06
HRP20161312T2 (hr) 2018-01-26
EP2799090B2 (en) 2020-03-04
LT2799089T (lt) 2016-11-10
US20130336898A1 (en) 2013-12-19
US20170189563A1 (en) 2017-07-06
JP5985523B2 (ja) 2016-09-06
ES2593127T9 (es) 2017-05-08
EP2799089A2 (en) 2014-11-05
HRP20140537T1 (hr) 2014-07-18
JP2014114306A (ja) 2014-06-26
PL2242515T3 (pl) 2014-08-29
ES2593127T3 (es) 2016-12-05
PL2799090T3 (pl) 2017-08-31
EP2591807A1 (en) 2013-05-15
PL2799090T5 (pl) 2020-07-13
EP2799090B1 (en) 2016-06-29
EP2242515A2 (en) 2010-10-27
ES2597782T3 (es) 2017-01-23
EP2799090A2 (en) 2014-11-05
WO2009103744A2 (en) 2009-08-27
JP2016117778A (ja) 2016-06-30
JP6422460B2 (ja) 2018-11-14
PT2799090T (pt) 2016-09-28
CA2714118A1 (en) 2009-08-27
LT2799090T (lt) 2016-10-10
EP2242515B1 (en) 2014-04-02
DK2799090T4 (da) 2020-05-18
KR20100133976A (ko) 2010-12-22
EP2242515B9 (en) 2014-10-01
DK2799089T3 (en) 2016-11-21
EP2799089A3 (en) 2015-03-04
PL2799089T3 (pl) 2017-08-31
ES2593127T5 (es) 2020-09-25
ES2477541T3 (es) 2014-07-17
US20160235868A1 (en) 2016-08-18
EP2799090A3 (en) 2015-01-14
WO2009103744A3 (en) 2009-12-17
DE202008010019U1 (de) 2009-07-02
EP2799090B9 (en) 2016-12-21
US20110129425A1 (en) 2011-06-02
EP2799089B1 (en) 2016-08-03
JP5469615B2 (ja) 2014-04-16
CN101977633A (zh) 2011-02-16
HUE031091T2 (en) 2017-06-28
US9636427B2 (en) 2017-05-02
CY1118985T1 (el) 2018-01-10
EP3159014A1 (en) 2017-04-26
CN101977633B (zh) 2012-08-29
KR101063060B1 (ko) 2011-09-07
US9655983B2 (en) 2017-05-23
JP2011514334A (ja) 2011-05-06
BRPI0908221B1 (pt) 2021-07-13
HRP20161312T1 (hr) 2016-12-16
PT2799089T (pt) 2016-10-25
DK2242515T3 (da) 2014-07-07
DK2799090T5 (en) 2017-04-18
DK2799090T3 (en) 2016-10-03
CA2714118C (en) 2017-03-28
BRPI0908221A2 (pt) 2018-03-20
HUE030219T2 (en) 2017-04-28
CY1115259T1 (el) 2017-01-04
US20160235867A1 (en) 2016-08-18
EP3620179A1 (en) 2020-03-11

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