RU2009141831A - Лечение мышечной дистрофии дюшенна - Google Patents

Лечение мышечной дистрофии дюшенна Download PDF

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Publication number
RU2009141831A
RU2009141831A RU2009141831/04A RU2009141831A RU2009141831A RU 2009141831 A RU2009141831 A RU 2009141831A RU 2009141831/04 A RU2009141831/04 A RU 2009141831/04A RU 2009141831 A RU2009141831 A RU 2009141831A RU 2009141831 A RU2009141831 A RU 2009141831A
Authority
RU
Russia
Prior art keywords
polymorphic form
ethylsulfonyl
naphthalen
oxazole
benzo
Prior art date
Application number
RU2009141831/04A
Other languages
English (en)
Russian (ru)
Inventor
Александр Чарльз УЭЙМУТ-УИЛСОН (GB)
Александр Чарльз УЭЙМУТ-УИЛСОН
Шабана АХМЕД (GB)
Шабана АХМЕД
Марк Уилльям ХУПЕР (GB)
Марк Уилльям ХУПЕР
Карен Джун ЭТЕРИНГТОН (GB)
Карен Джун ЭТЕРИНГТОН
Original Assignee
Байомарин Ига Лимитед (Bs)
Байомарин Ига Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Байомарин Ига Лимитед (Bs), Байомарин Ига Лимитед filed Critical Байомарин Ига Лимитед (Bs)
Publication of RU2009141831A publication Critical patent/RU2009141831A/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D263/57—Aryl or substituted aryl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
RU2009141831/04A 2007-08-15 2008-08-14 Лечение мышечной дистрофии дюшенна RU2009141831A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0715937.9 2007-08-15
GBGB0715937.9A GB0715937D0 (en) 2007-08-15 2007-08-15 Method of treatment og duchenne muscular dystrophy

Publications (1)

Publication Number Publication Date
RU2009141831A true RU2009141831A (ru) 2011-05-20

Family

ID=38566447

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2009141831/04A RU2009141831A (ru) 2007-08-15 2008-08-14 Лечение мышечной дистрофии дюшенна

Country Status (17)

Country Link
US (2) US20090048314A1 (enExample)
EP (2) EP2176246A2 (enExample)
JP (2) JP2010535829A (enExample)
KR (1) KR20100075777A (enExample)
CN (2) CN101896475A (enExample)
AR (1) AR068810A1 (enExample)
AU (2) AU2008286324A1 (enExample)
BR (2) BRPI0811548A2 (enExample)
CA (2) CA2685939A1 (enExample)
CL (1) CL2008002391A1 (enExample)
GB (1) GB0715937D0 (enExample)
IL (1) IL201908A0 (enExample)
MX (2) MX2009011916A (enExample)
PE (1) PE20090604A1 (enExample)
RU (1) RU2009141831A (enExample)
TW (1) TW200911767A (enExample)
WO (2) WO2009021748A2 (enExample)

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EP1986633B1 (en) * 2006-02-10 2014-07-30 Summit Corporation Plc Treatment of duchenne muscular dystrophy
GB201208178D0 (en) 2012-05-10 2012-06-20 Summit Corp Plc Pharmaceutical composition for the treatment of duchenne muscular dystrophy
GB201412010D0 (en) 2014-07-04 2014-08-20 Summit Corp Plc Treatment of hypertransaminasemia
KR20190026647A (ko) 2016-03-30 2019-03-13 서밋 (옥스포드) 리미티드 뒤쉔 근육 영양장애의 치료용 조성물
WO2017175842A1 (ja) * 2016-04-07 2017-10-12 国立大学法人京都大学 スプライシングの改変に関する化合物及び医薬組成物
KR102019048B1 (ko) 2017-02-06 2019-09-09 가톨릭대학교 산학협력단 MG53과 Orai1의 결합을 이용한 근육긴장저하 치료제 스크리닝 방법
KR101886788B1 (ko) 2017-02-07 2018-08-09 가톨릭대학교 산학협력단 MG53과 Orai1의 결합을 이용한 뒤시엔느 골격근 위축증 치료제 스크리닝 방법
EP4403171A3 (en) 2017-06-19 2024-09-11 University of Maryland, Baltimore Microtubule polymerization inhibitor prodrugs and methods of using the same

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Also Published As

Publication number Publication date
US20090048314A1 (en) 2009-02-19
JP2010535829A (ja) 2010-11-25
AU2008286324A1 (en) 2009-02-19
GB0715937D0 (en) 2007-09-26
AR068810A1 (es) 2009-12-09
CL2008002391A1 (es) 2009-05-22
CN101896475A (zh) 2010-11-24
AU2008286325A1 (en) 2009-02-19
EP2188270A2 (en) 2010-05-26
PE20090604A1 (es) 2009-05-16
BRPI0811315A2 (pt) 2015-01-27
WO2009021748A2 (en) 2009-02-19
MX2009011967A (es) 2009-11-19
WO2009021749A8 (en) 2009-09-11
WO2009021749A3 (en) 2009-04-02
EP2176246A2 (en) 2010-04-21
JP2010535830A (ja) 2010-11-25
KR20100075777A (ko) 2010-07-05
US20100267961A1 (en) 2010-10-21
WO2009021748A3 (en) 2009-04-02
CA2685590A1 (en) 2009-02-19
CA2685939A1 (en) 2009-02-19
CN101679323A (zh) 2010-03-24
US8138351B2 (en) 2012-03-20
WO2009021749A2 (en) 2009-02-19
BRPI0811548A2 (pt) 2014-11-18
TW200911767A (en) 2009-03-16
MX2009011916A (es) 2009-11-18
IL201908A0 (en) 2010-06-16

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Effective date: 20110906