KR20100075777A - 뒤시엔느 근이영양증의 치료를 위한 화합물의 다형체 - Google Patents
뒤시엔느 근이영양증의 치료를 위한 화합물의 다형체 Download PDFInfo
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- KR20100075777A KR20100075777A KR1020097023605A KR20097023605A KR20100075777A KR 20100075777 A KR20100075777 A KR 20100075777A KR 1020097023605 A KR1020097023605 A KR 1020097023605A KR 20097023605 A KR20097023605 A KR 20097023605A KR 20100075777 A KR20100075777 A KR 20100075777A
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- polymorph form
- ethylsulfonyl
- benzo
- naphthalen
- oxazole
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0715937.9 | 2007-08-15 | ||
| GBGB0715937.9A GB0715937D0 (en) | 2007-08-15 | 2007-08-15 | Method of treatment og duchenne muscular dystrophy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20100075777A true KR20100075777A (ko) | 2010-07-05 |
Family
ID=38566447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| KR1020097023605A Withdrawn KR20100075777A (ko) | 2007-08-15 | 2008-08-14 | 뒤시엔느 근이영양증의 치료를 위한 화합물의 다형체 |
Country Status (17)
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|---|---|
| US (2) | US8138351B2 (enExample) |
| EP (2) | EP2176246A2 (enExample) |
| JP (2) | JP2010535830A (enExample) |
| KR (1) | KR20100075777A (enExample) |
| CN (2) | CN101679323A (enExample) |
| AR (1) | AR068810A1 (enExample) |
| AU (2) | AU2008286325A1 (enExample) |
| BR (2) | BRPI0811315A2 (enExample) |
| CA (2) | CA2685939A1 (enExample) |
| CL (1) | CL2008002391A1 (enExample) |
| GB (1) | GB0715937D0 (enExample) |
| IL (1) | IL201908A0 (enExample) |
| MX (2) | MX2009011967A (enExample) |
| PE (1) | PE20090604A1 (enExample) |
| RU (1) | RU2009141831A (enExample) |
| TW (1) | TW200911767A (enExample) |
| WO (2) | WO2009021748A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101886788B1 (ko) | 2017-02-07 | 2018-08-09 | 가톨릭대학교 산학협력단 | MG53과 Orai1의 결합을 이용한 뒤시엔느 골격근 위축증 치료제 스크리닝 방법 |
| KR20180091981A (ko) | 2017-02-06 | 2018-08-17 | 가톨릭대학교 산학협력단 | MG53과 Orai1의 결합을 이용한 근육긴장저하 치료제 스크리닝 방법 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ570625A (en) * | 2006-02-10 | 2011-10-28 | Biomarin Iga Ltd | Treatment of duchenne muscular dystrophy |
| GB201208178D0 (en) | 2012-05-10 | 2012-06-20 | Summit Corp Plc | Pharmaceutical composition for the treatment of duchenne muscular dystrophy |
| GB201412010D0 (en) | 2014-07-04 | 2014-08-20 | Summit Corp Plc | Treatment of hypertransaminasemia |
| MX2018012018A (es) * | 2016-03-30 | 2019-07-04 | Summit Oxford Ltd | Composicion para el tratamiento de la distrofía muscular de duchenne. |
| WO2017175842A1 (ja) * | 2016-04-07 | 2017-10-12 | 国立大学法人京都大学 | スプライシングの改変に関する化合物及び医薬組成物 |
| EP3641741B1 (en) | 2017-06-19 | 2024-03-20 | University of Maryland, Baltimore | Microtubule polymerization inhibitor prodrugs and methods of using the same |
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| US3993659A (en) * | 1971-08-10 | 1976-11-23 | Ciba-Geigy Corporation | Bis-benzoxazolyl-naphthalenes as optical brighteners |
| CH617809GA3 (enExample) * | 1975-10-10 | 1980-06-30 | ||
| US4110246A (en) * | 1976-05-13 | 1978-08-29 | Hoechst Aktiengesellschaft | Mixture of benzoxazole derivatives |
| DE3027479A1 (de) * | 1980-07-19 | 1982-03-04 | Hoechst Ag, 6000 Frankfurt | Mischungen von optischen aufhellern und deren verwendung |
| JPS615071A (ja) * | 1984-06-15 | 1986-01-10 | Fuji Photo Film Co Ltd | ベンゾオキサゾ−ル誘導体 |
| DE3617451A1 (de) * | 1986-05-23 | 1987-11-26 | Hoechst Ag | Sulfonat- oder sulfonamidgruppen-haltige bis-benzoxazolylnaphthaline, verfahren zu deren herstellung und deren verwendung |
| DE3819051A1 (de) * | 1988-06-04 | 1989-12-07 | Agfa Gevaert Ag | Farbfotografisches aufzeichnungsmaterial |
| DE59206989D1 (de) * | 1991-08-08 | 1996-10-02 | Ciba Geigy Ag | Farbstoffe, Verfahren zu deren Herstellung und deren Verwendung |
| DE59509233D1 (de) * | 1994-02-24 | 2001-06-13 | Haarmann & Reimer Gmbh | Kosmetische und dermatologische zubereitungen, enthaltend phenylen-1,4-bisbenzimidiazolesulfonsäuren |
| US6004719A (en) * | 1994-04-25 | 1999-12-21 | Polaroid Corporation | Imaging medium and process for producing an image |
| CA2170375A1 (en) * | 1994-06-30 | 1996-01-11 | Sourav K. Kundu | Bioactive porous partition members |
| JP3928070B2 (ja) * | 1994-06-30 | 2007-06-13 | スリーエム カンパニー | 硬化指示性成形及びコーティング組成物 |
| US5567843A (en) * | 1995-03-20 | 1996-10-22 | The Dow Chemical Company | Process for making 2-aryl benz (ox, thi, imid)azoles and 2-aminoaryl aminobenz(ox, thi, imid)azoles |
| US6222044B1 (en) * | 1995-03-20 | 2001-04-24 | The Dow Chemical Company | Process for making 2-aryl benz (ox, thi, imid) azoles and 2-aminoaryl aminobenz (ox, thi, imid) azoles |
| US5977101A (en) * | 1995-06-29 | 1999-11-02 | Smithkline Beecham Corporation | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity |
| US5645948A (en) * | 1996-08-20 | 1997-07-08 | Eastman Kodak Company | Blue organic electroluminescent devices |
| US5914213A (en) * | 1996-11-27 | 1999-06-22 | Polaroid Corporation | Process and composition for generation of acid |
| US6110638A (en) * | 1996-11-27 | 2000-08-29 | Polaroid Corporation | Process and composition for generation of acid |
| US6177572B1 (en) * | 1997-08-20 | 2001-01-23 | Sepracor, Inc. | Solid and liquid-phase synthesis of benzoxazoles and benzothiazoles and their use |
| US6312822B1 (en) * | 1998-05-28 | 2001-11-06 | Eastman Chem Co | Dispersion aids for optical brighteners in polyolefins |
| GB9815880D0 (en) * | 1998-07-21 | 1998-09-16 | Pfizer Ltd | Heterocycles |
| US6436558B1 (en) * | 1998-08-07 | 2002-08-20 | Fuji Photo Film Co., Ltd. | Organic electroluminescence element |
| FR2789582B1 (fr) * | 1999-02-12 | 2001-05-04 | Oreal | Compositions photoprotectrices contenant un derive de bis-resorcinyl triazine et un compose a groupements benzoazolyle ou benzodiazolyle |
| FR2789581B1 (fr) * | 1999-02-12 | 2001-05-04 | Oreal | Compositions photoprotectrices contenant un derive de benzotriazole, un derive de bis-resorcinyl triazine et un compose a groupements benzoazolyle ou benzodiazolyle |
| DE50003732D1 (de) * | 1999-05-07 | 2003-10-23 | Basf Ag | 4-(3',4'-heterocyclylbenzoyl)pyrazole als herbizide |
| JP2002544201A (ja) * | 1999-05-07 | 2002-12-24 | ビーエーエスエフ アクチェンゲゼルシャフト | ベンゾヘテロシクリルシクロヘキセノン |
| FR2794645B1 (fr) * | 1999-06-08 | 2001-08-10 | Oreal | Compositions photoprotectrices contenant un compose hydrocarbone bis-hydroxyphenylbenzotriazole et un compose a groupements benzoazolyle ou benzodiazolyle |
| EP1215203B1 (en) * | 1999-09-24 | 2005-02-16 | Ono Pharmaceutical Co., Ltd. | Hydroxamic acid derivatives, process for the production thereof and drugs containing the same as the active ingredient |
| US6565987B2 (en) * | 1999-11-12 | 2003-05-20 | Eastman Chemical Company | Non-exuding optically brightened polyolefin blends |
| US6716413B1 (en) * | 2000-10-16 | 2004-04-06 | Mallinckrodt, Inc. | Indole compounds as tissue-specific exogenous optical agents |
| AU2002222566A1 (en) * | 2000-11-30 | 2002-06-11 | Canon Kabushiki Kaisha | Luminescent element and display |
| US20050261298A1 (en) * | 2002-01-18 | 2005-11-24 | David Solow-Cordero | Methods of treating conditions associated with an Edg-7 receptor |
| US20050113283A1 (en) * | 2002-01-18 | 2005-05-26 | David Solow-Cordero | Methods of treating conditions associated with an EDG-4 receptor |
| WO2003075921A2 (en) * | 2002-03-05 | 2003-09-18 | Transtech Pharma, Inc. | Mono- and bicyclic azole derivatives that inhibit the interaction of ligands with rage |
| AU2003261834A1 (en) * | 2002-08-30 | 2004-05-04 | Bf Research Institute, Inc. | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein |
| CA2523808A1 (en) * | 2003-05-16 | 2004-12-23 | Ambit Biosciences Corporation | Pyrrole compounds and uses thereof |
| CN1805743A (zh) * | 2003-05-20 | 2006-07-19 | 特兰斯泰克制药公司 | 用作逆转淀粉样变性及其他与之相关疾病的rage拮抗剂 |
| CN102060806A (zh) * | 2003-09-11 | 2011-05-18 | iTherX药品公司 | 细胞因子抑制剂 |
| CN1882879B (zh) * | 2003-09-22 | 2010-08-11 | 爱克发印艺公司 | 可光聚合的组合物 |
| US7097888B2 (en) * | 2003-12-15 | 2006-08-29 | Eastman Kodak Company | Aligned liquid crystal layer containing azolium salts and process for increasing the tilt |
| US7592373B2 (en) * | 2003-12-23 | 2009-09-22 | Boehringer Ingelheim International Gmbh | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds |
| WO2005074375A2 (en) * | 2004-02-06 | 2005-08-18 | Insight Biopharmaceuticals Ltd | Heparanase inhibitors and uses thereof |
| MY144903A (en) * | 2004-06-17 | 2011-11-30 | Novartis Ag | Pyrrolopyridine derivatives and their use as crth2 antagonists |
| JP2008510312A (ja) * | 2004-08-19 | 2008-04-03 | エルジー・ケム・リミテッド | バッファ層を含む有機発光素子およびその製作方法 |
| US7723340B2 (en) * | 2005-01-13 | 2010-05-25 | Signal Pharmaceuticals, Llc | Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith |
| US7893267B2 (en) * | 2005-03-14 | 2011-02-22 | High Point Pharmaceuticals, Llc | Benzazole derivatives, compositions, and methods of use as β-secretase inhibitors |
| JP2007086165A (ja) * | 2005-09-20 | 2007-04-05 | Fujifilm Corp | 感光性組成物、これを用いた平版印刷版原版及び画像記録方法 |
| CN101336124B (zh) * | 2005-12-02 | 2012-06-13 | 塞克姆公司 | 阴离子交换顶替色谱法及在阴离子交换顶替色谱法中作为置换剂化合物的阴离子有机化合物 |
| KR101213485B1 (ko) * | 2006-01-27 | 2012-12-18 | 삼성디스플레이 주식회사 | 유기 금속 착물 및 이를 이용한 유기 전계 발광 소자 |
| KR101213486B1 (ko) * | 2006-02-02 | 2012-12-20 | 삼성디스플레이 주식회사 | 유기 금속 착물 및 이를 이용한 유기 전계 발광 소자 |
| NZ570625A (en) * | 2006-02-10 | 2011-10-28 | Biomarin Iga Ltd | Treatment of duchenne muscular dystrophy |
| KR101325062B1 (ko) * | 2006-05-19 | 2013-11-05 | 삼성디스플레이 주식회사 | 발광 이종 핵 구리-이리듐 착체 및 이를 이용한 유기 전계발광 소자 |
-
2007
- 2007-08-15 GB GBGB0715937.9A patent/GB0715937D0/en not_active Ceased
-
2008
- 2008-08-14 WO PCT/EP2008/006718 patent/WO2009021748A2/en not_active Ceased
- 2008-08-14 CN CN200880015864A patent/CN101679323A/zh active Pending
- 2008-08-14 CN CN2008800158003A patent/CN101896475A/zh active Pending
- 2008-08-14 BR BRPI0811315-7A2A patent/BRPI0811315A2/pt not_active Application Discontinuation
- 2008-08-14 RU RU2009141831/04A patent/RU2009141831A/ru not_active Application Discontinuation
- 2008-08-14 JP JP2010520499A patent/JP2010535830A/ja active Pending
- 2008-08-14 AU AU2008286325A patent/AU2008286325A1/en not_active Abandoned
- 2008-08-14 AU AU2008286324A patent/AU2008286324A1/en not_active Abandoned
- 2008-08-14 CA CA002685939A patent/CA2685939A1/en not_active Abandoned
- 2008-08-14 BR BRPI0811548-6A2A patent/BRPI0811548A2/pt not_active Application Discontinuation
- 2008-08-14 EP EP08785565A patent/EP2176246A2/en not_active Withdrawn
- 2008-08-14 CA CA002685590A patent/CA2685590A1/en not_active Abandoned
- 2008-08-14 TW TW097131010A patent/TW200911767A/zh unknown
- 2008-08-14 JP JP2010520498A patent/JP2010535829A/ja active Pending
- 2008-08-14 EP EP08785566A patent/EP2188270A2/en not_active Withdrawn
- 2008-08-14 US US12/599,970 patent/US8138351B2/en not_active Expired - Fee Related
- 2008-08-14 PE PE2008001385A patent/PE20090604A1/es not_active Application Discontinuation
- 2008-08-14 US US12/192,053 patent/US20090048314A1/en not_active Abandoned
- 2008-08-14 MX MX2009011967A patent/MX2009011967A/es not_active Application Discontinuation
- 2008-08-14 CL CL2008002391A patent/CL2008002391A1/es unknown
- 2008-08-14 WO PCT/EP2008/006719 patent/WO2009021749A2/en not_active Ceased
- 2008-08-14 AR ARP080103560A patent/AR068810A1/es not_active Application Discontinuation
- 2008-08-14 MX MX2009011916A patent/MX2009011916A/es not_active Application Discontinuation
- 2008-08-14 KR KR1020097023605A patent/KR20100075777A/ko not_active Withdrawn
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2009
- 2009-11-03 IL IL201908A patent/IL201908A0/en unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20180091981A (ko) | 2017-02-06 | 2018-08-17 | 가톨릭대학교 산학협력단 | MG53과 Orai1의 결합을 이용한 근육긴장저하 치료제 스크리닝 방법 |
| KR101886788B1 (ko) | 2017-02-07 | 2018-08-09 | 가톨릭대학교 산학협력단 | MG53과 Orai1의 결합을 이용한 뒤시엔느 골격근 위축증 치료제 스크리닝 방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| MX2009011967A (es) | 2009-11-19 |
| CN101896475A (zh) | 2010-11-24 |
| AR068810A1 (es) | 2009-12-09 |
| WO2009021749A8 (en) | 2009-09-11 |
| CA2685590A1 (en) | 2009-02-19 |
| IL201908A0 (en) | 2010-06-16 |
| WO2009021749A3 (en) | 2009-04-02 |
| EP2188270A2 (en) | 2010-05-26 |
| JP2010535830A (ja) | 2010-11-25 |
| GB0715937D0 (en) | 2007-09-26 |
| JP2010535829A (ja) | 2010-11-25 |
| US20100267961A1 (en) | 2010-10-21 |
| US8138351B2 (en) | 2012-03-20 |
| AU2008286325A1 (en) | 2009-02-19 |
| MX2009011916A (es) | 2009-11-18 |
| PE20090604A1 (es) | 2009-05-16 |
| BRPI0811548A2 (pt) | 2014-11-18 |
| EP2176246A2 (en) | 2010-04-21 |
| WO2009021748A2 (en) | 2009-02-19 |
| WO2009021748A3 (en) | 2009-04-02 |
| CA2685939A1 (en) | 2009-02-19 |
| US20090048314A1 (en) | 2009-02-19 |
| CN101679323A (zh) | 2010-03-24 |
| AU2008286324A1 (en) | 2009-02-19 |
| RU2009141831A (ru) | 2011-05-20 |
| CL2008002391A1 (es) | 2009-05-22 |
| TW200911767A (en) | 2009-03-16 |
| WO2009021749A2 (en) | 2009-02-19 |
| BRPI0811315A2 (pt) | 2015-01-27 |
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