BRPI0709466A2 - compopsto, composição farmacêutica, métoo para ligar receptores opiódes em um paciente necessitado dos mesmos, método para melhorar a sobrevivência de orgão e células, método para prover cárdioproteção, método para reduzir a necessidade de anestesia, método para produzir ou manter um estado anestésico, derivado rádio-rotulado de um composto e método de produção de imagem de diagnóstico - Google Patents
compopsto, composição farmacêutica, métoo para ligar receptores opiódes em um paciente necessitado dos mesmos, método para melhorar a sobrevivência de orgão e células, método para prover cárdioproteção, método para reduzir a necessidade de anestesia, método para produzir ou manter um estado anestésico, derivado rádio-rotulado de um composto e método de produção de imagem de diagnóstico Download PDFInfo
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- BRPI0709466A2 BRPI0709466A2 BRPI0709466-3A BRPI0709466A BRPI0709466A2 BR PI0709466 A2 BRPI0709466 A2 BR PI0709466A2 BR PI0709466 A BRPI0709466 A BR PI0709466A BR PI0709466 A2 BRPI0709466 A2 BR PI0709466A2
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- BR
- Brazil
- Prior art keywords
- spiro
- piperidine
- disorder
- compound according
- diethylaminocarbonyl
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Classifications
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Gynecology & Obstetrics (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79041606P | 2006-04-06 | 2006-04-06 | |
| US60/790,416 | 2006-04-06 | ||
| US11/696,585 | 2007-04-04 | ||
| US11/696,585 US7576207B2 (en) | 2006-04-06 | 2007-04-04 | Spirocyclic heterocyclic derivatives and methods of their use |
| PCT/US2007/066071 WO2007118151A2 (en) | 2006-04-06 | 2007-04-05 | Spirocyclic heterocyclic derivatives and methods of their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0709466A2 true BRPI0709466A2 (pt) | 2011-07-19 |
Family
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Family Applications (1)
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|---|---|---|---|
| BRPI0709466-3A BRPI0709466A2 (pt) | 2006-04-06 | 2007-04-05 | compopsto, composição farmacêutica, métoo para ligar receptores opiódes em um paciente necessitado dos mesmos, método para melhorar a sobrevivência de orgão e células, método para prover cárdioproteção, método para reduzir a necessidade de anestesia, método para produzir ou manter um estado anestésico, derivado rádio-rotulado de um composto e método de produção de imagem de diagnóstico |
Country Status (11)
| Country | Link |
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| US (2) | US7576207B2 (enExample) |
| EP (1) | EP2001467A4 (enExample) |
| JP (1) | JP2009533353A (enExample) |
| KR (1) | KR20090014157A (enExample) |
| AU (1) | AU2007234762A1 (enExample) |
| BR (1) | BRPI0709466A2 (enExample) |
| CA (1) | CA2648287A1 (enExample) |
| CO (1) | CO6140027A2 (enExample) |
| IL (1) | IL194292A0 (enExample) |
| MX (1) | MX2008012856A (enExample) |
| WO (1) | WO2007118151A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0415165A (pt) * | 2003-10-01 | 2007-01-09 | Adolor Corp | composto heterocìclico espirocìclico, composição farmacêutica, método para ligar receptores opióides, métodos para prevenir ou tratar dor, disfunção gastrointestinal, um distúrbio do trato urogenital, um distúrbio imunomodulatório, um distúrbio inflamatório, um distúrbio de função respiratória, ansiedade, distúrbio do humor, um distúrbio relacionado a estresse, distúrbio do sistema nervoso simpático, tosse, e um distúrbio motor, método para tratar uma lesão traumática ao sistema nervoso central, métodos para prevenir ou tratar acidente vascular, arritmia cardìaca, glaucoma, e disfunção sexual, métodos para tratar uma condição selecionada do grupo consistindo de choque, edema cerebral, isquemia cerebral, déficit cerebral após cirurgia cardìaca (bypass) e enxerto, lupus eritematoso sistêmico, doença de hodgkin, doença de sjogren, epilepsia, e rejeição em transplantes de órgão e enxertos de pele, e para tratar dependência de substáncias, métodos para melhorar a sobrevivência de órgãos e células, e cardioproteção após infarto do miocárdio, métodos para reduzir a necessidade de anestesia, para produzir ou manter um estado anestésico, derivado radiomarcado de um composto, derivado isotopicamente marcado de um composto, composto e método de diagnóstico por imagem |
| US7576207B2 (en) * | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| AU2007294968A1 (en) * | 2006-09-12 | 2008-03-20 | Adolor Corporation | Use of N-containing spirocompounds for the enhancement of cognitive function |
| FR2907121B1 (fr) * | 2006-10-12 | 2012-05-04 | Neorphys | Nouveaux derives morphiniques |
| JO3126B1 (ar) * | 2007-11-14 | 2017-09-20 | Janssen Pharmaceutica Nv | مثبطات ناقل نيوكليوسيد متوازن اي ان تي 1 |
| US9408837B2 (en) * | 2008-05-28 | 2016-08-09 | Kitov Pharmaceutical Ltd. | Ameliorating drug-induced elevations in blood pressure by adjunctive use of antihypertensive drugs |
| CN104136442B (zh) * | 2012-01-16 | 2016-12-21 | 沃泰克斯药物股份有限公司 | 作为离子通道调节剂的吡喃‑螺环哌啶酰胺类 |
| WO2014138669A1 (en) | 2013-03-07 | 2014-09-12 | Mindlab LLC | Pain medicine combination and uses thereof |
| EP3512600A4 (en) | 2016-09-13 | 2020-05-27 | Mindlab LLC | DRUG COMBINATIONS AND TREATMENT OF RESTLESS LEG SYNDROME |
| CN110179988A (zh) * | 2019-07-10 | 2019-08-30 | 王大伟 | 五羟色胺再摄取抑制剂和单胺氧化酶抑制剂联合在制备治疗抑郁症或早泄药物中的应用 |
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| BRPI0415165A (pt) * | 2003-10-01 | 2007-01-09 | Adolor Corp | composto heterocìclico espirocìclico, composição farmacêutica, método para ligar receptores opióides, métodos para prevenir ou tratar dor, disfunção gastrointestinal, um distúrbio do trato urogenital, um distúrbio imunomodulatório, um distúrbio inflamatório, um distúrbio de função respiratória, ansiedade, distúrbio do humor, um distúrbio relacionado a estresse, distúrbio do sistema nervoso simpático, tosse, e um distúrbio motor, método para tratar uma lesão traumática ao sistema nervoso central, métodos para prevenir ou tratar acidente vascular, arritmia cardìaca, glaucoma, e disfunção sexual, métodos para tratar uma condição selecionada do grupo consistindo de choque, edema cerebral, isquemia cerebral, déficit cerebral após cirurgia cardìaca (bypass) e enxerto, lupus eritematoso sistêmico, doença de hodgkin, doença de sjogren, epilepsia, e rejeição em transplantes de órgão e enxertos de pele, e para tratar dependência de substáncias, métodos para melhorar a sobrevivência de órgãos e células, e cardioproteção após infarto do miocárdio, métodos para reduzir a necessidade de anestesia, para produzir ou manter um estado anestésico, derivado radiomarcado de um composto, derivado isotopicamente marcado de um composto, composto e método de diagnóstico por imagem |
| BRPI0509377A (pt) * | 2004-03-29 | 2007-09-11 | Pfizer | compostos de ácido alfa arila ou heteroaril metil beta piperidino propanóico como antagonistas do receptor orl1 |
| US7598261B2 (en) * | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| US7576207B2 (en) * | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| AU2007294968A1 (en) * | 2006-09-12 | 2008-03-20 | Adolor Corporation | Use of N-containing spirocompounds for the enhancement of cognitive function |
-
2007
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- 2007-04-05 CA CA002648287A patent/CA2648287A1/en not_active Abandoned
- 2007-04-05 MX MX2008012856A patent/MX2008012856A/es not_active Application Discontinuation
- 2007-04-05 JP JP2009504476A patent/JP2009533353A/ja active Pending
- 2007-04-05 AU AU2007234762A patent/AU2007234762A1/en not_active Abandoned
- 2007-04-05 WO PCT/US2007/066071 patent/WO2007118151A2/en not_active Ceased
- 2007-04-05 KR KR1020087027224A patent/KR20090014157A/ko not_active Ceased
- 2007-04-05 BR BRPI0709466-3A patent/BRPI0709466A2/pt not_active IP Right Cessation
- 2007-04-05 EP EP07760193A patent/EP2001467A4/en not_active Withdrawn
-
2008
- 2008-09-23 IL IL194292A patent/IL194292A0/en unknown
- 2008-10-21 CO CO08112132A patent/CO6140027A2/es unknown
-
2009
- 2009-07-27 US US12/509,549 patent/US20100196269A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL194292A0 (en) | 2009-09-22 |
| EP2001467A2 (en) | 2008-12-17 |
| AU2007234762A1 (en) | 2007-10-18 |
| US20100196269A1 (en) | 2010-08-05 |
| EP2001467A4 (en) | 2009-11-18 |
| KR20090014157A (ko) | 2009-02-06 |
| CA2648287A1 (en) | 2007-10-18 |
| CO6140027A2 (es) | 2010-03-19 |
| US20070269374A1 (en) | 2007-11-22 |
| WO2007118151A2 (en) | 2007-10-18 |
| MX2008012856A (es) | 2009-02-23 |
| JP2009533353A (ja) | 2009-09-17 |
| US7576207B2 (en) | 2009-08-18 |
| WO2007118151A3 (en) | 2008-07-03 |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
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