BRPI0608402B8 - compostos de flavonóide e composições compreendendo os mesmos - Google Patents

compostos de flavonóide e composições compreendendo os mesmos

Info

Publication number
BRPI0608402B8
BRPI0608402B8 BRPI0608402A BRPI0608402A BRPI0608402B8 BR PI0608402 B8 BRPI0608402 B8 BR PI0608402B8 BR PI0608402 A BRPI0608402 A BR PI0608402A BR PI0608402 A BRPI0608402 A BR PI0608402A BR PI0608402 B8 BRPI0608402 B8 BR PI0608402B8
Authority
BR
Brazil
Prior art keywords
compounds
flavonoid compounds
compositions
flavonoid
nutraceutical
Prior art date
Application number
BRPI0608402A
Other languages
English (en)
Portuguese (pt)
Inventor
Jarrott Bevyn
Newton May Clive
James Dusting Gregory
Llewellyn Woodman Owen
Original Assignee
Armaron Bio Pty Ltd
Howard Florey Inst
Howard Florey Inst Of Experimental Physiology And Medicine
Neuprotect Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2005901214A external-priority patent/AU2005901214A0/en
Application filed by Armaron Bio Pty Ltd, Howard Florey Inst, Howard Florey Inst Of Experimental Physiology And Medicine, Neuprotect Pty Ltd filed Critical Armaron Bio Pty Ltd
Publication of BRPI0608402A2 publication Critical patent/BRPI0608402A2/pt
Publication of BRPI0608402B1 publication Critical patent/BRPI0608402B1/pt
Publication of BRPI0608402B8 publication Critical patent/BRPI0608402B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pyrane Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0608402A 2005-03-11 2006-03-10 compostos de flavonóide e composições compreendendo os mesmos BRPI0608402B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2005901214 2005-03-11
AU2005901214A AU2005901214A0 (en) 2005-03-11 Flavonoid compounds and uses thereof
PCT/AU2006/000314 WO2006094357A1 (en) 2005-03-11 2006-03-10 Flavonoid compounds and uses thereof

Publications (3)

Publication Number Publication Date
BRPI0608402A2 BRPI0608402A2 (pt) 2009-12-29
BRPI0608402B1 BRPI0608402B1 (pt) 2020-10-13
BRPI0608402B8 true BRPI0608402B8 (pt) 2021-05-25

Family

ID=36952879

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0608402A BRPI0608402B8 (pt) 2005-03-11 2006-03-10 compostos de flavonóide e composições compreendendo os mesmos

Country Status (15)

Country Link
US (1) US8017649B2 (enExample)
EP (1) EP1856085B1 (enExample)
JP (1) JP5380069B2 (enExample)
KR (1) KR101397510B1 (enExample)
CN (1) CN101137639B (enExample)
AU (1) AU2006222556B2 (enExample)
BR (1) BRPI0608402B8 (enExample)
CA (1) CA2601028C (enExample)
DK (1) DK1856085T3 (enExample)
ES (1) ES2552108T3 (enExample)
NZ (1) NZ560633A (enExample)
RU (1) RU2431634C2 (enExample)
SG (1) SG162773A1 (enExample)
WO (1) WO2006094357A1 (enExample)
ZA (1) ZA200707427B (enExample)

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BRPI0608402B8 (pt) 2005-03-11 2021-05-25 Armaron Bio Pty Ltd compostos de flavonóide e composições compreendendo os mesmos
AU2006233256B2 (en) * 2006-10-30 2012-01-19 Armaron Bio Pty Ltd Improved flavonols
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CN104387360B (zh) * 2014-11-21 2016-10-05 潍坊医学院 柚皮素脂肪酸酯、其制备方法和以该化合物为活性成分的药物组合物及其应用
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CN105153093B (zh) * 2015-08-29 2017-07-21 西南民族大学 一种黄酮类化合物及其制备方法和用途
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CN106632479B (zh) * 2016-12-22 2018-10-23 贵州大学 O,o’-二烷基-o”-(取代黄酮-3-基)磷酸酯类衍生物、制备方法及应用
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CN107382941B (zh) * 2017-07-10 2020-05-08 石家庄学院 黄酮衍生物及其制备方法和应用
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CN109280067B (zh) * 2017-07-21 2022-07-05 南京正大天晴制药有限公司 香叶木苷衍生物、其制备方法以及医药用途
CN107550902A (zh) * 2017-10-31 2018-01-09 上海华堇生物技术有限责任公司 黄颜木素的药物用途
CN108752378A (zh) * 2018-07-12 2018-11-06 四川福思达生物技术开发有限责任公司 一种甲基次磷酸单烷基酯的合成方法
CN108997426B (zh) * 2018-07-19 2020-11-13 大连理工大学 靶向Hsp60的黄酮烷氧基氨基磷酸酯衍生物、制备及应用
CN114656579A (zh) * 2020-12-22 2022-06-24 安庆北化大科技园有限公司 一种低毒的黄酮醇磺酸酯类光引发剂及可见光引发体系和应用
CN113045527B (zh) * 2021-03-22 2022-11-08 广东省科学院动物研究所 二氢色原酮衍生物及其合成方法和用途
CN113321633B (zh) * 2021-05-21 2022-03-15 湖北工业大学 槲皮素-3-o-乙酸-(3-氯-4-硫代氨基)-苯酯及在制备糖尿病药物中的应用
CN115504970B (zh) * 2022-10-18 2023-04-18 黑龙江中医药大学 一种用于治疗心肌缺血的黄酮类衍生物及其制备方法
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CN119504681B (zh) * 2024-11-27 2025-11-18 河南中烟工业有限责任公司 一种降焦减刺潜香化合物、制备方法、应用及应用方法

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CN101137639A (zh) 2008-03-05
SG162773A1 (en) 2010-07-29
ES2552108T3 (es) 2015-11-25
WO2006094357A1 (en) 2006-09-14
EP1856085A4 (en) 2010-11-03
KR101397510B1 (ko) 2014-05-22
US8017649B2 (en) 2011-09-13
RU2007137659A (ru) 2009-04-20
ZA200707427B (en) 2008-11-26
AU2006222556A1 (en) 2006-09-14
DK1856085T3 (en) 2015-10-05
BRPI0608402A2 (pt) 2009-12-29
BRPI0608402B1 (pt) 2020-10-13
CA2601028A1 (en) 2006-09-14
KR20070114315A (ko) 2007-11-30
CN101137639B (zh) 2012-05-23
EP1856085B1 (en) 2015-07-08
US20090130051A1 (en) 2009-05-21
CA2601028C (en) 2014-05-27
RU2431634C2 (ru) 2011-10-20
AU2006222556B2 (en) 2011-09-29
EP1856085A1 (en) 2007-11-21
JP5380069B2 (ja) 2014-01-08
NZ560633A (en) 2011-08-26
JP2008532951A (ja) 2008-08-21

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