BRPI0516803A - oxilipinas de ácidos graxos polinsaturados de cadeia longa e métodos de produção e uso dos mesmos - Google Patents
oxilipinas de ácidos graxos polinsaturados de cadeia longa e métodos de produção e uso dos mesmosInfo
- Publication number
- BRPI0516803A BRPI0516803A BRPI0516803-1A BRPI0516803A BRPI0516803A BR PI0516803 A BRPI0516803 A BR PI0516803A BR PI0516803 A BRPI0516803 A BR PI0516803A BR PI0516803 A BRPI0516803 A BR PI0516803A
- Authority
- BR
- Brazil
- Prior art keywords
- oxylipines
- dpan
- production
- derived
- long chain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6432—Eicosapentaenoic acids [EPA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6434—Docosahexenoic acids [DHA]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62984204P | 2004-11-19 | 2004-11-19 | |
| US72903805P | 2005-10-21 | 2005-10-21 | |
| PCT/US2005/042462 WO2006055965A2 (en) | 2004-11-19 | 2005-11-21 | Oxylipins from long chain polyunsaturated fatty acids and methods of making and using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0516803A true BRPI0516803A (pt) | 2008-09-23 |
Family
ID=36407879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0516803-1A BRPI0516803A (pt) | 2004-11-19 | 2005-11-21 | oxilipinas de ácidos graxos polinsaturados de cadeia longa e métodos de produção e uso dos mesmos |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7884131B2 (https=) |
| EP (1) | EP1824809A4 (https=) |
| JP (1) | JP2008520739A (https=) |
| KR (1) | KR20070090928A (https=) |
| CN (1) | CN101102988B (https=) |
| AU (1) | AU2005306320B2 (https=) |
| BR (1) | BRPI0516803A (https=) |
| CA (1) | CA2588166A1 (https=) |
| EA (1) | EA010802B1 (https=) |
| IL (1) | IL183246A0 (https=) |
| MX (1) | MX2007006049A (https=) |
| NZ (1) | NZ555394A (https=) |
| WO (1) | WO2006055965A2 (https=) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7893106B2 (en) * | 2004-11-19 | 2011-02-22 | Martek Biosciences, Corporation | Oxylipins from stearidonic acid and γ-linolenic acid and methods of making and using the same |
| US20090318394A1 (en) * | 2004-11-19 | 2009-12-24 | Julie Nauroth | Long Chain Polyunsaturated Fatty Acids and Methods of Making and Using the Same |
| BRPI0613358A8 (pt) * | 2005-07-08 | 2017-12-26 | Dsm Ip Assets Bv | ácidos de gordura poli - insaturada para o tratamento da demência e condições relacionadas à pré-demência |
| US8273792B2 (en) * | 2005-10-03 | 2012-09-25 | The Brigham And Women's Hospital, Inc. | Anti-inflammatory actions of neuroprotectin D1/protectin D1 and it's natural stereoisomers |
| EP1983977A4 (en) * | 2006-01-31 | 2011-11-30 | Martek Biosciences Corp | OXYLIPINES FROM STEARIDONIC ACID AND GAMMA-LINOLIC ACID AND METHOD FOR THE PRODUCTION AND USE THEREOF |
| GB0604647D0 (en) | 2006-03-08 | 2006-04-19 | Shchepinov Mikhail | Stabilized food supplements and their derivatives |
| CA2650607A1 (en) * | 2006-04-28 | 2007-11-08 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for the treatment of cardiovascular disease |
| JP2009545527A (ja) * | 2006-07-19 | 2009-12-24 | リゾルヴィクス・ファーマシューティカルズ・インコーポレイテッド | 粘膜炎の治療用の組成物及び方法 |
| EP2131833A2 (en) * | 2006-10-26 | 2009-12-16 | Resolvyx Pharmaceuticals, Inc. | Use of resolvins for inhibition of bone loss |
| WO2008070129A2 (en) * | 2006-12-05 | 2008-06-12 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for the treatment of inflammatory disease |
| EP2120920A4 (en) * | 2007-02-20 | 2011-06-15 | Martek Biosciences Corp | OXYLIPINES OF LONG-CHAIN MULTIPLE-UNSATURATED FATTY ACIDS AND METHOD FOR THEIR PREPARATION AND USE |
| PE20090186A1 (es) * | 2007-03-23 | 2009-03-20 | Novartis Ag | Composicion farmaceutica que comprende una sal de cobre recubierta o encapsulada |
| US20100159540A1 (en) * | 2007-03-26 | 2010-06-24 | Ana Rodriguez | Synthesis of resolvins and intermediates, compounds prepared thereby, and uses thereof |
| EP2679224A1 (en) | 2007-08-01 | 2014-01-01 | University of Pittsburgh of the Commonwealth System of Higher Education | Nitro oleic acid modulation of type II diabetes |
| CA2699483A1 (en) * | 2007-09-14 | 2009-03-26 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for modulating immune function |
| JP5421272B2 (ja) * | 2007-10-12 | 2014-02-19 | リゾルヴィクス・ファーマシューティカルズ・インコーポレイテッド | 眼病治療のための組成物及び方法 |
| US20110027841A1 (en) * | 2007-12-21 | 2011-02-03 | Martek Biosciences Corporation | Method for preparation of oxylipins |
| CN102083787A (zh) | 2008-05-01 | 2011-06-01 | 康普雷克萨公司 | 乙烯基取代的脂肪酸 |
| US20140024713A1 (en) | 2008-06-19 | 2014-01-23 | University Of Utah Research Foundation | Use of nitrated lipids for treatment of side effects of toxic medical therapies |
| WO2009155439A2 (en) | 2008-06-19 | 2009-12-23 | University Of Utah Research Foundation | Use of nitrated lipids for treatment of side effects of toxic medical therapies |
| ES2792676T3 (es) | 2008-09-16 | 2020-11-11 | Brigham & Womens Hospital Inc | Compuestos del ácido 14-hidroxi-docosahexaenoico |
| PT2349250T (pt) * | 2008-10-31 | 2017-07-25 | Lipid Pharmaceuticals Ehf | Ácidos gordos para uso como um medicamento |
| EP2415748A4 (en) * | 2009-02-20 | 2013-08-07 | Univ Tokyo | NEW INFLAMMATORY COMPOUNDS |
| ES2345241B1 (es) | 2009-03-16 | 2011-09-08 | Lipopharma Therapeutics | Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos. |
| CA2756528A1 (en) * | 2009-04-17 | 2010-10-21 | Celavista Pharmaceuticals Limited | Compositions rich in omega-3 fatty acids with a low content in phytanic acid |
| EP3318255B1 (en) | 2009-06-15 | 2021-03-10 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for treating stroke in a subject on concomitant statin therapy |
| EP2459189A4 (en) * | 2009-07-31 | 2013-01-16 | Univ Pittsburgh | FATTY ACIDS AS ANTI-INFLAMMATORY AGENTS |
| CA2772618C (en) | 2009-09-01 | 2018-08-21 | Catabasis Pharmaceuticals, Inc. | Fatty acid niacin conjugates and their uses |
| USRE46608E1 (en) | 2009-09-01 | 2017-11-14 | Catabasis Pharmaceuticals, Inc. | Fatty acid niacin conjugates and their uses |
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| CA2777827C (en) | 2009-10-30 | 2020-08-18 | Retrotope, Inc. | Alleviating oxidative stress disorders with pufa derivatives |
| JP5909183B2 (ja) * | 2010-08-19 | 2016-04-26 | 国立大学法人 東京大学 | オメガ3系脂肪酸由来の新規抗炎症性代謝物 |
| JPWO2012026106A1 (ja) * | 2010-08-25 | 2013-10-28 | 国立大学法人 東京大学 | 光学活性な新規抗炎症性化合物及びその製造方法 |
| NZ744990A (en) | 2010-11-29 | 2019-10-25 | Amarin Pharmaceuticals Ie Ltd | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
| US11712429B2 (en) | 2010-11-29 | 2023-08-01 | Amarin Pharmaceuticals Ireland Limited | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
| AU2012249920B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Disorders implicating PUFA oxidation |
| AU2012249918B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Impaired energy processing disorders and mitochondrial deficiency |
| EP3689342A1 (en) | 2011-04-26 | 2020-08-05 | Retrotope, Inc. | Oxidative retinal diseases |
| AU2012249917B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Neurodegenerative disorders and muscle diseases implicating PUFAs |
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| EP2744491B1 (en) | 2011-08-19 | 2020-07-29 | The University of Utah Research Foundation | Combination therapy with nitrated lipids and inhibitors of the renin-angiotensin-aldosterone system |
| US10322118B2 (en) * | 2012-04-10 | 2019-06-18 | Trustees Of Dartmouth College | Compounds and methods for inhibiting Cif virulence factor |
| DK2858496T3 (da) | 2012-05-10 | 2023-07-24 | Solutex Na Llc | Olier med anti-inflammatorisk aktivitet, som indeholder naturlige specialiserede pro-afhjælpningsmediatorer og deres forløbere |
| WO2013192109A1 (en) | 2012-06-17 | 2013-12-27 | Matinas Biopharma, Inc. | Omega-3 pentaenoic acid compositions and methods of use |
| PL2887923T3 (pl) | 2012-08-24 | 2023-08-14 | Sun Pharmaceutical Industries Limited | Preparat okulistyczny polioksylipidu lub polioksylowego kwasu tłuszczowego i leczenie chorób oczu |
| WO2014110261A1 (en) * | 2013-01-11 | 2014-07-17 | Massachusetts Eye And Ear Infirmary | Cyp450 lipid metabolites reduce inflammation and angiogenesis |
| WO2014130894A1 (en) * | 2013-02-21 | 2014-08-28 | University Of Southern California | Compositions for the treatment of inflammatory diseases |
| WO2014143272A1 (en) * | 2013-03-13 | 2014-09-18 | Matinas Biopharma Inc. | Omega-3 pentaenoic acid compositions and methods of use |
| EP3892608B1 (en) * | 2013-05-30 | 2025-07-23 | The Brigham and Women's Hospital, Inc. | Novel n-3 immunoresolvents: structures and actions |
| JP7025212B2 (ja) * | 2015-02-09 | 2022-02-24 | ボード オブ スーパーバイザーズ オブ ルイジアナ ステート ユニバーシティ アンド アグリカルチュアル アンド メカニカル カレッジ | 炎症性、変性及び神経変性疾患の治療のための化合物、組成物及び方法 |
| HRP20240082T1 (hr) | 2015-07-07 | 2024-03-29 | H. Lundbeck A/S | Inhibitor pde9 s okosnicom imidazopirazinona za liječenje perifernih bolesti |
| US20180208536A1 (en) * | 2015-07-20 | 2018-07-26 | The Brigham And Women's Hospital, Inc. | Elucidation of Novel 13-Series Resolvins that Increase with Atorvastatin and Clear Infections |
| US10653703B2 (en) | 2015-09-03 | 2020-05-19 | Solutex Na Llc | Compositions comprising omega-3 fatty acids, 17-HDHA and 18-HEPE and methods of using same |
| IL258476B2 (en) | 2015-10-02 | 2023-04-01 | Complexa Inc | Prevention, treatment and reversal of disease using therapeutically effective amounts of activated fatty acids |
| EP3373976B1 (en) | 2015-11-10 | 2024-01-03 | Sun Pharmaceutical Industries Limited | Topical formulations and uses thereof |
| CA3005983A1 (en) | 2015-11-23 | 2017-06-01 | Retrotope, Inc. | Site-specific isotopic labeling of 1,4-diene systems |
| WO2019104315A1 (en) * | 2017-11-27 | 2019-05-31 | Brown University | Compositions and methods using lipids for treating neurological disease |
| WO2019104311A1 (en) * | 2017-11-27 | 2019-05-31 | Brown University | Compositions and methods for suppressing neurological disease |
| EP3792351A4 (en) | 2018-04-16 | 2022-01-19 | Korea Research Institute of Bioscience and Biotechnology | Method for producing multi-hydroxy derivatives of polyunsaturated fatty acids |
| FI3801526T3 (fi) | 2018-05-25 | 2024-03-20 | Cardurion Pharmaceuticals Inc | 6-[(3s,4s)-4-metyyli-1-(pyrimidin-2-yylimetyyli)pyrrolidin-3-yyli]-3-tetrahydropyran-4-yyli-7h-imidatso[1,5-a]pyratsin-8-onin monohydraattimuotoja ja kiteisiä muotoja |
| EP3843737A4 (en) | 2018-08-31 | 2022-06-01 | Imara Inc. | PDE9 INHIBITORS FOR THE TREATMENT OF SICKLE CELL DISEASE |
| LT3750536T (lt) | 2018-09-24 | 2026-03-25 | Amarin Pharmaceuticals Ireland Limited | Širdies ir kraujagyslių sistemos reiškinių rizikos subjekto organizme sumažinimo būdai |
| KR102673270B1 (ko) * | 2018-10-15 | 2024-06-07 | (주)아모레퍼시픽 | 피부장벽 강화용 조성물 |
| KR102704402B1 (ko) | 2018-10-24 | 2024-09-06 | (주)아모레퍼시픽 | 피부장벽 강화용 조성물 |
| BR112022009189A2 (pt) | 2019-11-12 | 2022-07-26 | Amarin Pharmaceuticals Ie Ltd | Métodos para reduzir o risco de eventos cardiovasculares em um sujeito com fibrilação atrial e/ou palpitação atrial |
| CA3172351A1 (en) | 2020-02-21 | 2021-08-26 | Retrotope, Inc. | Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof |
| US12109194B2 (en) | 2021-02-05 | 2024-10-08 | Biojiva Llc | Synergistic combination therapy for treating ALS |
| AU2022263358A1 (en) | 2021-04-21 | 2023-11-30 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing the risk of heart failure |
| KR20220159751A (ko) | 2021-05-26 | 2022-12-05 | (주)아모레퍼시픽 | 미백용 조성물 및 이를 이용한 피부 미백방법 |
| WO2024229108A1 (en) * | 2023-05-01 | 2024-11-07 | The Regents Of The University Of California | In-situ production of anti-inflammatory lipids using milk fat globules |
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| JPH11209259A (ja) * | 1998-01-20 | 1999-08-03 | Noevir Co Ltd | 皮膚化粧料 |
| KR100423013B1 (ko) | 1999-03-04 | 2004-03-12 | 산토리 가부시키가이샤 | 도코사펜타엔산 함유물질의 이용 |
| CA2378968A1 (en) | 1999-07-07 | 2001-01-18 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing hydroxylated fatty acid and o-lactones |
| EP1228026B1 (en) | 1999-11-09 | 2004-01-02 | Alcon Inc. | 15-hydroxyeicosatetraenoic acid-related compounds and methods of use |
| JP4932116B2 (ja) * | 2000-02-16 | 2012-05-16 | ザ・ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド | アスピリン誘発脂質メディエータ |
| DE10046541A1 (de) | 2000-09-19 | 2002-03-28 | Knoll Ag | Mechanisch stabile darreichungsformen, enthaltend Ubichinone |
| US7154022B2 (en) | 2000-10-06 | 2006-12-26 | Board Of Trustees Operating Michigan State University | Divinyl ether synthase gene, and protein and uses thereof |
| EP1392623A4 (en) * | 2001-05-14 | 2005-05-04 | Martek Biosciences Corp | PREPARATION AND USE OF A POLAR LIPID RICH FRACTION CONTAINING HIGHLY UNSATURATED OMEGA-3 AND / OR OMEGA-6 FATTY ACIDS FROM MICROBES, SEEDS OF GENETICALLY MODIFIED PLANTS AND MARINE ORGANISMS |
| AU2002365167A1 (en) * | 2001-12-18 | 2003-07-09 | The Brigham And Women's Hospital | Inhibition or prevention of infection by bacteria with epa, dha or analogs |
| US7527935B2 (en) | 2002-03-19 | 2009-05-05 | Mitsubishi Tanabe Pharma Corporation | G-protein coupled receptor having eicosanoid as ligand and gene thereof |
| US7582785B2 (en) | 2002-04-01 | 2009-09-01 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid derivatives |
| WO2003084305A2 (en) | 2002-04-01 | 2003-10-16 | University Of Southern California | Trihydroxy polyunsaturated eicosanoids |
| FR2843124B1 (fr) | 2002-08-02 | 2004-10-15 | Goemar Lab Sa | Procede de preparation d'acides gras polyinsatures libres et de leurs metabolites d'oxydation |
| DE60330154D1 (de) * | 2002-08-12 | 2009-12-31 | Brigham & Womens Hospital | Resolvine: biotemplate zur durchführung therapeutischer anwendungen |
| US20040166130A1 (en) | 2002-12-23 | 2004-08-26 | L'oreal | Lanolin-free cosmetic composition comprising a hydroxylated fatty acid aromatic ester |
| US7893106B2 (en) | 2004-11-19 | 2011-02-22 | Martek Biosciences, Corporation | Oxylipins from stearidonic acid and γ-linolenic acid and methods of making and using the same |
-
2005
- 2005-11-21 WO PCT/US2005/042462 patent/WO2006055965A2/en not_active Ceased
- 2005-11-21 KR KR1020077013738A patent/KR20070090928A/ko not_active Ceased
- 2005-11-21 EP EP05846821A patent/EP1824809A4/en not_active Withdrawn
- 2005-11-21 CN CN2005800468877A patent/CN101102988B/zh not_active Expired - Fee Related
- 2005-11-21 US US11/284,790 patent/US7884131B2/en not_active Expired - Fee Related
- 2005-11-21 AU AU2005306320A patent/AU2005306320B2/en not_active Ceased
- 2005-11-21 MX MX2007006049A patent/MX2007006049A/es active IP Right Grant
- 2005-11-21 EA EA200701100A patent/EA010802B1/ru not_active IP Right Cessation
- 2005-11-21 BR BRPI0516803-1A patent/BRPI0516803A/pt not_active IP Right Cessation
- 2005-11-21 NZ NZ555394A patent/NZ555394A/en not_active IP Right Cessation
- 2005-11-21 JP JP2007543444A patent/JP2008520739A/ja active Pending
- 2005-11-21 CA CA002588166A patent/CA2588166A1/en not_active Abandoned
-
2007
- 2007-05-15 IL IL183246A patent/IL183246A0/en unknown
-
2010
- 2010-12-29 US US12/981,261 patent/US20110178047A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL183246A0 (en) | 2007-08-19 |
| US20060241088A1 (en) | 2006-10-26 |
| US20110178047A1 (en) | 2011-07-21 |
| MX2007006049A (es) | 2007-07-24 |
| KR20070090928A (ko) | 2007-09-06 |
| EP1824809A2 (en) | 2007-08-29 |
| EA200701100A1 (ru) | 2007-10-26 |
| JP2008520739A (ja) | 2008-06-19 |
| US7884131B2 (en) | 2011-02-08 |
| EP1824809A4 (en) | 2010-03-03 |
| AU2005306320A1 (en) | 2006-05-26 |
| WO2006055965A2 (en) | 2006-05-26 |
| WO2006055965A3 (en) | 2006-11-30 |
| CN101102988B (zh) | 2011-12-14 |
| EA010802B1 (ru) | 2008-12-30 |
| AU2005306320B2 (en) | 2011-09-08 |
| CA2588166A1 (en) | 2006-05-26 |
| CN101102988A (zh) | 2008-01-09 |
| NZ555394A (en) | 2010-07-30 |
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