HK1256301A1 - 提高阿托伐他汀和清除感染的新的 13 系列消退素的說明 - Google Patents

提高阿托伐他汀和清除感染的新的 13 系列消退素的說明

Info

Publication number
HK1256301A1
HK1256301A1 HK18115366.4A HK18115366A HK1256301A1 HK 1256301 A1 HK1256301 A1 HK 1256301A1 HK 18115366 A HK18115366 A HK 18115366A HK 1256301 A1 HK1256301 A1 HK 1256301A1
Authority
HK
Hong Kong
Prior art keywords
elucidation
atorvastatin
novel
increase
series resolvins
Prior art date
Application number
HK18115366.4A
Other languages
English (en)
Inventor
Jesmond Dalli
Nan Chiang
Charles N Serhan
Original Assignee
Brigham & Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham & Womens Hospital Inc filed Critical Brigham & Womens Hospital Inc
Publication of HK1256301A1 publication Critical patent/HK1256301A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK18115366.4A 2015-07-20 2018-11-30 提高阿托伐他汀和清除感染的新的 13 系列消退素的說明 HK1256301A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562194485P 2015-07-20 2015-07-20
PCT/US2016/042932 WO2017015271A1 (en) 2015-07-20 2016-07-19 Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections

Publications (1)

Publication Number Publication Date
HK1256301A1 true HK1256301A1 (zh) 2019-09-20

Family

ID=57834588

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18115366.4A HK1256301A1 (zh) 2015-07-20 2018-11-30 提高阿托伐他汀和清除感染的新的 13 系列消退素的說明

Country Status (5)

Country Link
US (2) US20180208536A1 (zh)
EP (1) EP3325438A4 (zh)
JP (1) JP6820312B2 (zh)
HK (1) HK1256301A1 (zh)
WO (1) WO2017015271A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201706747D0 (en) * 2017-04-27 2017-06-14 Queen Mary Method and apparatus for determining the efficacy of statins for treating inflammatory diseases in idividual patients
GB201715115D0 (en) * 2017-09-19 2017-11-01 Univ London Queen Mary Methods for assessing risk of cardiovascular disease and methods and compounds for use in treating or preventing cardiovascular disease
US20230399295A1 (en) * 2020-11-04 2023-12-14 The Brigham And Women's Hospital, Inc. Compositions for increasing tissue regeneration and delaying or reducing granuloma formation
CN113402385B (zh) * 2021-07-20 2022-08-26 湖北大学 源自真菌代谢产物的抗菌化合物、制备方法及应用
WO2023168245A2 (en) 2022-03-03 2023-09-07 Thetis Pharmaceuticals Llc Cyclodextrin complexes of specialized proresolving mediators
CN115317472A (zh) * 2022-07-20 2022-11-11 重庆市畜牧科学院 ResolvinD1在制备缓解肠道细胞凋亡药物中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7902257B2 (en) * 2002-04-01 2011-03-08 University Of Southern California Trihydroxy polyunsaturated eicosanoid
US7884131B2 (en) * 2004-11-19 2011-02-08 Martek Biosciences, Corporation Oxylipins from long chain polyunsaturated fatty acids and methods of making and using the same
EP1954291A1 (en) * 2005-11-18 2008-08-13 Trustees Of Boston University Treatment and prevention of bone loss using resolvins
CN101663031A (zh) * 2007-02-20 2010-03-03 马泰克生物科学公司 来自长链多不饱和脂肪酸的氧脂素及其制备方法和使用方法
WO2008153426A1 (en) * 2007-06-15 2008-12-18 Sealord Group Limited Anti-inflammatory composition and use thereof
ES2569371T3 (es) 2008-09-16 2016-05-10 The Brigham And Women's Hospital Inc. Compuestos del ácido 7,14-dihidroxidocosahexaenoico
EP2415748A4 (en) * 2009-02-20 2013-08-07 Univ Tokyo NEW INFLAMMATORY COMPOUNDS
EP3003299B8 (en) * 2013-05-30 2021-08-18 The Brigham and Women's Hospital, Inc. Novel n-3 immunoresolvents: structures and actions
US9447020B2 (en) * 2013-10-31 2016-09-20 Scf Pharma Inc. Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof

Also Published As

Publication number Publication date
WO2017015271A1 (en) 2017-01-26
JP2018525359A (ja) 2018-09-06
JP6820312B2 (ja) 2021-01-27
US20200048177A1 (en) 2020-02-13
US20180208536A1 (en) 2018-07-26
EP3325438A1 (en) 2018-05-30
US11555006B2 (en) 2023-01-17
EP3325438A4 (en) 2019-04-03

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