BRPI0509146B8 - sistema de liberação de droga, método de fabricação do mesmo, e, uso do sistema de liberação de droga - Google Patents
sistema de liberação de droga, método de fabricação do mesmo, e, uso do sistema de liberação de drogaInfo
- Publication number
- BRPI0509146B8 BRPI0509146B8 BRPI0509146A BRPI0509146A BRPI0509146B8 BR PI0509146 B8 BRPI0509146 B8 BR PI0509146B8 BR PI0509146 A BRPI0509146 A BR PI0509146A BR PI0509146 A BRPI0509146 A BR PI0509146A BR PI0509146 B8 BRPI0509146 B8 BR PI0509146B8
- Authority
- BR
- Brazil
- Prior art keywords
- delivery system
- drug delivery
- ethylene
- vinyl acetate
- copolymer
- Prior art date
Links
- 238000012377 drug delivery Methods 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 9
- 239000005038 ethylene vinyl acetate Substances 0.000 abstract 6
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 abstract 6
- -1 poly(ethylene-vinyl acetate) copolymer Polymers 0.000 abstract 6
- 230000000757 progestagenic effect Effects 0.000 abstract 5
- 229920001169 thermoplastic Polymers 0.000 abstract 5
- 239000004416 thermosoftening plastic Substances 0.000 abstract 5
- 230000001076 estrogenic effect Effects 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04101215 | 2004-03-24 | ||
EP04101215.4 | 2004-03-24 | ||
PCT/EP2005/051189 WO2005089723A1 (en) | 2004-03-24 | 2005-03-16 | Drug delivery system based on polyethylene vinylacetate copolymers |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0509146A BRPI0509146A (pt) | 2007-09-04 |
BRPI0509146B1 BRPI0509146B1 (pt) | 2018-03-20 |
BRPI0509146B8 true BRPI0509146B8 (pt) | 2021-05-25 |
Family
ID=34928924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0509146A BRPI0509146B8 (pt) | 2004-03-24 | 2005-03-16 | sistema de liberação de droga, método de fabricação do mesmo, e, uso do sistema de liberação de droga |
Country Status (17)
Country | Link |
---|---|
US (3) | US8481079B2 (pt) |
EP (1) | EP1732520B1 (pt) |
JP (1) | JP2007530500A (pt) |
CN (1) | CN100531800C (pt) |
AR (1) | AR048185A1 (pt) |
AT (1) | ATE434433T1 (pt) |
AU (1) | AU2005224056B2 (pt) |
BR (1) | BRPI0509146B8 (pt) |
CA (1) | CA2559224C (pt) |
DE (1) | DE602005015090D1 (pt) |
ES (1) | ES2327247T3 (pt) |
IL (1) | IL178018A (pt) |
MX (1) | MXPA06010905A (pt) |
MY (1) | MY142824A (pt) |
PE (1) | PE20060127A1 (pt) |
TW (1) | TWI290837B (pt) |
WO (1) | WO2005089723A1 (pt) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE372772T1 (de) | 2004-07-13 | 2007-09-15 | Schering Oy | Retardiertes freigabesystem mit kontrollierter initialabgabe |
RU2463018C2 (ru) * | 2006-11-20 | 2012-10-10 | Н.В. Органон | Устройство доставки лекарственного средства, имеющее спиральную форму |
MX2009005445A (es) * | 2006-11-22 | 2009-06-02 | Organon Nv | Sistema de suministro para risperidona. |
AR066166A1 (es) * | 2007-09-21 | 2009-07-29 | Organon Nv | Sistema de suministro de droga |
EP2062568A1 (en) * | 2007-11-22 | 2009-05-27 | Bayer Schering Pharma Oy | Vaginal delivery system |
ATE508734T1 (de) * | 2007-11-22 | 2011-05-15 | Bayer Oy | System zur vaginalen freisetzung |
TW200927141A (en) * | 2007-11-22 | 2009-07-01 | Bayer Schering Pharma Oy | Vaginal delivery system |
EP2408423A2 (en) | 2009-03-17 | 2012-01-25 | Intervet International B.V. | Zoo-technical drug delivery device |
WO2010106046A1 (en) * | 2009-03-17 | 2010-09-23 | Intervet International B.V. | Macrocyclic lactone drug delivery system |
JP5813093B2 (ja) * | 2010-03-28 | 2015-11-17 | エベストラ・インコーポレイテッドEvestra,Inc. | 膣内薬物送達デバイス |
US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
CN104168902A (zh) | 2011-08-26 | 2014-11-26 | 智利圣地亚哥大学 | 阴道内给药非类固醇抗炎药物美洛昔康和吡罗昔康用于中断女性排卵过程的用途 |
TW201332585A (zh) | 2012-02-14 | 2013-08-16 | Chemo Res S L | 核鞘藥物遞送裝置 |
TR201808748T4 (tr) | 2012-09-03 | 2018-07-23 | Ecosea Farming S A | Hidrobiyolojik türlerin kültürü ve/veya korunmasına yönelik rezervuar-kafes daldırma sistemi. |
US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
WO2015086489A1 (en) | 2013-12-11 | 2015-06-18 | Merck Sharp & Dohme B.V. | Drug delivery system for delivery of anti-virals |
US10413504B2 (en) * | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
CN104306380A (zh) * | 2014-09-18 | 2015-01-28 | 新疆特丰药业股份有限公司 | 结合雌激素和醋酸甲羟孕酮双层片及其制备方法 |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
US10406336B2 (en) | 2016-08-03 | 2019-09-10 | Neil S. Davey | Adjustable rate drug delivery implantable device |
EP3395335A1 (en) * | 2017-04-24 | 2018-10-31 | Kern Pharma, S.L. | Vaginal ring for the simultaneous release of two active ingredients |
MX2020012459A (es) | 2018-05-24 | 2021-04-28 | Celanese Eva Performance Polymers Llc | Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular. |
JP2021524841A (ja) | 2018-05-24 | 2021-09-16 | セラニーズ・イーブイエイ・パフォーマンス・ポリマーズ・エルエルシー | 高分子薬剤化合物の持続放出用の埋め込み型デバイス |
CN113365634A (zh) * | 2018-12-11 | 2021-09-07 | 卢品公司 | 超低剂量雌激素组合的药物递送系统及其方法和用途 |
US11439588B2 (en) * | 2019-10-12 | 2022-09-13 | National Research Institute For Family Planning | Vaginal sustained-release drug delivery system for luteal support, method for preparation and use thereof |
KR102159904B1 (ko) | 2020-04-24 | 2020-09-24 | 강경원 | 약물 방출 고리를 구비한 월경컵 |
WO2023200974A1 (en) * | 2022-04-14 | 2023-10-19 | Yale University | Nanoparticles and nanoparticle-releasing vaginal rings |
WO2024030116A1 (en) * | 2022-08-01 | 2024-02-08 | Lupin Inc. | Drug delivery system for ultra-low dose estrogen combinations and methods and uses thereof |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3995634A (en) | 1975-12-02 | 1976-12-07 | The Procter & Gamble Company | Vaginal cavity dispensing means and method |
US3995633A (en) | 1975-12-02 | 1976-12-07 | The Procter & Gamble Company | Vaginal Medicament dispensing device |
US4237885A (en) | 1978-10-23 | 1980-12-09 | Alza Corporation | Delivery system with mated members for storing and releasing a plurality of beneficial agents |
US4292965A (en) | 1978-12-29 | 1981-10-06 | The Population Council, Inc. | Intravaginal ring |
DE3040978A1 (de) | 1980-10-28 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Vaginalring |
US4596576A (en) | 1984-10-12 | 1986-06-24 | Akzo N.V. | Release system for two or more active substances |
AU6360896A (en) | 1995-07-04 | 1997-02-05 | Akzo Nobel N.V. | Ring-shaped devices |
TW358031B (en) | 1997-04-11 | 1999-05-11 | Akze Nobel N V | Drug delivery system for 2 or more active substances |
BR9813523B1 (pt) | 1997-12-12 | 2009-01-13 | embalagem assÉptica envolvendo um artigo intravaginal. |
-
2005
- 2005-03-16 JP JP2007504403A patent/JP2007530500A/ja not_active Withdrawn
- 2005-03-16 BR BRPI0509146A patent/BRPI0509146B8/pt not_active IP Right Cessation
- 2005-03-16 AT AT05717059T patent/ATE434433T1/de not_active IP Right Cessation
- 2005-03-16 WO PCT/EP2005/051189 patent/WO2005089723A1/en not_active Application Discontinuation
- 2005-03-16 CA CA2559224A patent/CA2559224C/en active Active
- 2005-03-16 CN CNB2005800093236A patent/CN100531800C/zh not_active Expired - Fee Related
- 2005-03-16 MX MXPA06010905A patent/MXPA06010905A/es active IP Right Grant
- 2005-03-16 TW TW094108065A patent/TWI290837B/zh not_active IP Right Cessation
- 2005-03-16 DE DE602005015090T patent/DE602005015090D1/de active Active
- 2005-03-16 US US10/594,104 patent/US8481079B2/en active Active
- 2005-03-16 ES ES05717059T patent/ES2327247T3/es active Active
- 2005-03-16 EP EP05717059A patent/EP1732520B1/en not_active Not-in-force
- 2005-03-16 AU AU2005224056A patent/AU2005224056B2/en not_active Ceased
- 2005-03-22 PE PE2005000327A patent/PE20060127A1/es not_active Application Discontinuation
- 2005-03-23 AR ARP050101144A patent/AR048185A1/es unknown
- 2005-03-24 MY MYPI20051277A patent/MY142824A/en unknown
-
2006
- 2006-09-11 IL IL178018A patent/IL178018A/en not_active IP Right Cessation
-
2013
- 2013-06-05 US US13/910,250 patent/US8808744B2/en active Active
-
2014
- 2014-06-23 US US14/312,034 patent/US20140302115A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE434433T1 (de) | 2009-07-15 |
EP1732520A1 (en) | 2006-12-20 |
MY142824A (en) | 2011-01-14 |
BRPI0509146B1 (pt) | 2018-03-20 |
US8808744B2 (en) | 2014-08-19 |
IL178018A0 (en) | 2006-12-31 |
CN100531800C (zh) | 2009-08-26 |
ES2327247T3 (es) | 2009-10-27 |
US20070141102A1 (en) | 2007-06-21 |
CN1933820A (zh) | 2007-03-21 |
AR048185A1 (es) | 2006-04-05 |
BRPI0509146A (pt) | 2007-09-04 |
EP1732520B1 (en) | 2009-06-24 |
IL178018A (en) | 2010-05-17 |
TW200536572A (en) | 2005-11-16 |
CA2559224A1 (en) | 2005-09-29 |
US20140302115A1 (en) | 2014-10-09 |
US20130266632A1 (en) | 2013-10-10 |
DE602005015090D1 (de) | 2009-08-06 |
AU2005224056B2 (en) | 2010-03-18 |
AU2005224056A1 (en) | 2005-09-29 |
CA2559224C (en) | 2011-12-13 |
PE20060127A1 (es) | 2006-03-15 |
TWI290837B (en) | 2007-12-11 |
WO2005089723A1 (en) | 2005-09-29 |
JP2007530500A (ja) | 2007-11-01 |
MXPA06010905A (es) | 2007-03-08 |
US8481079B2 (en) | 2013-07-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: MSD OSS B.V. (NL) |
|
B25A | Requested transfer of rights approved |
Owner name: ORGANON BIOSCIENCES NEDERLAND B.V. (NL) |
|
B25A | Requested transfer of rights approved |
Owner name: MERCK SHARP AND DOHME B.V. (NL) |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 20/03/2018, OBSERVADAS AS CONDICOES LEGAIS. |
|
B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/03/2005 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
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B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 19A ANUIDADE. |
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B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2766 DE 09-01-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |