AR048185A1 - Sistema de entrega de farmacos constituido por uno o mas compartimentos, que comprende un compuesto progestagenico disuelto en un copolimero de polietileno acetato de vinilo termoplastico - Google Patents
Sistema de entrega de farmacos constituido por uno o mas compartimentos, que comprende un compuesto progestagenico disuelto en un copolimero de polietileno acetato de vinilo termoplasticoInfo
- Publication number
- AR048185A1 AR048185A1 ARP050101144A ARP050101144A AR048185A1 AR 048185 A1 AR048185 A1 AR 048185A1 AR P050101144 A ARP050101144 A AR P050101144A AR P050101144 A ARP050101144 A AR P050101144A AR 048185 A1 AR048185 A1 AR 048185A1
- Authority
- AR
- Argentina
- Prior art keywords
- vinyl acetate
- polyethylene copolymer
- delivery system
- progestagenic
- thermoplastic vinyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Un sistema de entrega de fármacos constituido por uno o más compartimentos y que comprende un compuesto progestagénico disuelto en un copolímero de polietileno acetato de vinilo termoplástico, donde si el sistema de entrega está constituido por un compartimento, el compartimento comprende: i) un nucleo de un copolímero de polietileno acetato de vinilo termoplástico que comprende el compuesto progestagénico, esta disuelto en el copolímero de polietileno acetato de vinilo hasta una concentracion inferior al nivel de saturacion a 25 degree C, y un compuesto estrogénico; y ii) un forro de un copolímero de polietileno acetato de vinilo termoplástico que cubre el nucleo, siendo dicho forro permeable para ambos compuestos; si el sistema de entrega está constituido por más de un compartimento, solo un compartimento comprende: iii) el compuesto progestagénico, cuyo compuesto progestagénico está disuelto en un nucleo de un copolímero de polietileno acetato de vinilo termoplástico hasta una concentracion inferior al nivel de saturacion a 25 degree C, y un compuesto estrogénico; y iv) un forro de un copolímero de polietileno acetato de vinilo termoplástico que cubre el nucleo, siendo dicho forro permeable para ambos compuestos. Reivindicacion 15: Uso del sistema de entrega de fármacos de las reivindicaciones 1-12, caracterizado porque sirve para la fabricacion de un kit anticonceptivo o un kit para terapia de reemplazo hormonal.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04101215 | 2004-03-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR048185A1 true AR048185A1 (es) | 2006-04-05 |
Family
ID=34928924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP050101144A AR048185A1 (es) | 2004-03-24 | 2005-03-23 | Sistema de entrega de farmacos constituido por uno o mas compartimentos, que comprende un compuesto progestagenico disuelto en un copolimero de polietileno acetato de vinilo termoplastico |
Country Status (17)
Country | Link |
---|---|
US (3) | US8481079B2 (es) |
EP (1) | EP1732520B1 (es) |
JP (1) | JP2007530500A (es) |
CN (1) | CN100531800C (es) |
AR (1) | AR048185A1 (es) |
AT (1) | ATE434433T1 (es) |
AU (1) | AU2005224056B2 (es) |
BR (1) | BRPI0509146B8 (es) |
CA (1) | CA2559224C (es) |
DE (1) | DE602005015090D1 (es) |
ES (1) | ES2327247T3 (es) |
IL (1) | IL178018A (es) |
MX (1) | MXPA06010905A (es) |
MY (1) | MY142824A (es) |
PE (1) | PE20060127A1 (es) |
TW (1) | TWI290837B (es) |
WO (1) | WO2005089723A1 (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2293193T5 (es) † | 2004-07-13 | 2012-06-13 | Bayer Schering Pharma Oy | Sistema de suministro retardado con descarga inicial controlada |
EP2097063B1 (en) * | 2006-11-20 | 2013-08-07 | Intervet International B.V. | Helically-shaped drug delivery system |
CA2670454A1 (en) * | 2006-11-22 | 2008-05-29 | N.V. Organon | Delivery system for a non-steroidal non-ionized hydrophilic drug |
US8741329B2 (en) * | 2007-09-21 | 2014-06-03 | Merck Sharp & Dohme B.V. | Drug delivery system |
EP2062568A1 (en) * | 2007-11-22 | 2009-05-27 | Bayer Schering Pharma Oy | Vaginal delivery system |
TW200927141A (en) * | 2007-11-22 | 2009-07-01 | Bayer Schering Pharma Oy | Vaginal delivery system |
DK2062569T3 (da) * | 2007-11-22 | 2011-08-29 | Bayer Oy | Vaginalt afgivelsessystem |
UY32492A (es) | 2009-03-17 | 2010-10-29 | Organon Nv | Dispositivo de suministro de droga zootécnica. |
JP2012520847A (ja) * | 2009-03-17 | 2012-09-10 | インターベツト・インターナシヨナル・ベー・ベー | 大環状ラクトン薬物送達システム |
CN103025320A (zh) * | 2010-03-28 | 2013-04-03 | 伊万斯彻有限公司 | 阴道内药物递送装置 |
US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
WO2013029194A1 (es) | 2011-08-26 | 2013-03-07 | Universidad De Santiago De Chile | Uso de los anti-inflamatorios no esteroidales meloxicam y piroxicam, por via intravaginal, para la interrupción del proceso ovulatorio en la mujer |
TW201332585A (zh) | 2012-02-14 | 2013-08-16 | Chemo Res S L | 核鞘藥物遞送裝置 |
WO2014032199A1 (es) | 2012-09-03 | 2014-03-06 | Ecosea Farming S.A. | Sistema de hundimiento de balsa-jaula destinadas al cultivo y/o confinamiento de especies hidrobiologicas |
US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
US10413504B2 (en) * | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
EP3079659B1 (en) | 2013-12-11 | 2020-10-28 | Merck Sharp & Dohme B.V. | Drug delivery system for delivery of anti-virals |
CN104306380A (zh) * | 2014-09-18 | 2015-01-28 | 新疆特丰药业股份有限公司 | 结合雌激素和醋酸甲羟孕酮双层片及其制备方法 |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
US10406336B2 (en) | 2016-08-03 | 2019-09-10 | Neil S. Davey | Adjustable rate drug delivery implantable device |
EP3395335A1 (en) * | 2017-04-24 | 2018-10-31 | Kern Pharma, S.L. | Vaginal ring for the simultaneous release of two active ingredients |
AU2019275409A1 (en) | 2018-05-24 | 2020-07-16 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
SG11202005947RA (en) | 2018-05-24 | 2020-07-29 | Celanese Eva Performance Polymers Corp | Implantable device for sustained release of a macromolecular drug compound |
CN113365634A (zh) * | 2018-12-11 | 2021-09-07 | 卢品公司 | 超低剂量雌激素组合的药物递送系统及其方法和用途 |
WO2021068239A1 (zh) * | 2019-10-12 | 2021-04-15 | 国家卫生健康委科学技术研究所 | 用于黄体支持的阴道缓释给药系统及其制备方法与应用 |
KR102159904B1 (ko) | 2020-04-24 | 2020-09-24 | 강경원 | 약물 방출 고리를 구비한 월경컵 |
WO2023200974A1 (en) * | 2022-04-14 | 2023-10-19 | Yale University | Nanoparticles and nanoparticle-releasing vaginal rings |
WO2024030116A1 (en) * | 2022-08-01 | 2024-02-08 | Lupin Inc. | Drug delivery system for ultra-low dose estrogen combinations and methods and uses thereof |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3995634A (en) | 1975-12-02 | 1976-12-07 | The Procter & Gamble Company | Vaginal cavity dispensing means and method |
US3995633A (en) | 1975-12-02 | 1976-12-07 | The Procter & Gamble Company | Vaginal Medicament dispensing device |
US4237885A (en) | 1978-10-23 | 1980-12-09 | Alza Corporation | Delivery system with mated members for storing and releasing a plurality of beneficial agents |
US4292965A (en) | 1978-12-29 | 1981-10-06 | The Population Council, Inc. | Intravaginal ring |
DE3040978A1 (de) | 1980-10-28 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Vaginalring |
EP0180264A1 (en) | 1984-10-12 | 1986-05-07 | Akzo N.V. | Release system for two or more active substances |
US6544546B1 (en) * | 1995-07-04 | 2003-04-08 | Akzo Nobel, N.V. | Ring-shaped devices |
IL123813A0 (en) * | 1997-04-11 | 1998-10-30 | Akzo Nobel Nv | Drug delivery system for two or more active substances |
IL136307A (en) | 1997-12-12 | 2004-03-28 | Akzo Nobel Nv | Packing for holster ring |
-
2005
- 2005-03-16 MX MXPA06010905A patent/MXPA06010905A/es active IP Right Grant
- 2005-03-16 EP EP05717059A patent/EP1732520B1/en not_active Not-in-force
- 2005-03-16 AU AU2005224056A patent/AU2005224056B2/en not_active Ceased
- 2005-03-16 JP JP2007504403A patent/JP2007530500A/ja not_active Withdrawn
- 2005-03-16 AT AT05717059T patent/ATE434433T1/de not_active IP Right Cessation
- 2005-03-16 TW TW094108065A patent/TWI290837B/zh not_active IP Right Cessation
- 2005-03-16 BR BRPI0509146A patent/BRPI0509146B8/pt not_active IP Right Cessation
- 2005-03-16 DE DE602005015090T patent/DE602005015090D1/de active Active
- 2005-03-16 US US10/594,104 patent/US8481079B2/en active Active
- 2005-03-16 CN CNB2005800093236A patent/CN100531800C/zh not_active Expired - Fee Related
- 2005-03-16 CA CA2559224A patent/CA2559224C/en active Active
- 2005-03-16 ES ES05717059T patent/ES2327247T3/es active Active
- 2005-03-16 WO PCT/EP2005/051189 patent/WO2005089723A1/en not_active Application Discontinuation
- 2005-03-22 PE PE2005000327A patent/PE20060127A1/es not_active Application Discontinuation
- 2005-03-23 AR ARP050101144A patent/AR048185A1/es unknown
- 2005-03-24 MY MYPI20051277A patent/MY142824A/en unknown
-
2006
- 2006-09-11 IL IL178018A patent/IL178018A/en not_active IP Right Cessation
-
2013
- 2013-06-05 US US13/910,250 patent/US8808744B2/en active Active
-
2014
- 2014-06-23 US US14/312,034 patent/US20140302115A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
TW200536572A (en) | 2005-11-16 |
BRPI0509146B8 (pt) | 2021-05-25 |
MXPA06010905A (es) | 2007-03-08 |
AU2005224056B2 (en) | 2010-03-18 |
CN1933820A (zh) | 2007-03-21 |
ES2327247T3 (es) | 2009-10-27 |
IL178018A0 (en) | 2006-12-31 |
CA2559224C (en) | 2011-12-13 |
AU2005224056A1 (en) | 2005-09-29 |
US20130266632A1 (en) | 2013-10-10 |
BRPI0509146A (pt) | 2007-09-04 |
US20070141102A1 (en) | 2007-06-21 |
EP1732520A1 (en) | 2006-12-20 |
US8481079B2 (en) | 2013-07-09 |
TWI290837B (en) | 2007-12-11 |
WO2005089723A1 (en) | 2005-09-29 |
US8808744B2 (en) | 2014-08-19 |
MY142824A (en) | 2011-01-14 |
BRPI0509146B1 (pt) | 2018-03-20 |
DE602005015090D1 (de) | 2009-08-06 |
JP2007530500A (ja) | 2007-11-01 |
CA2559224A1 (en) | 2005-09-29 |
ATE434433T1 (de) | 2009-07-15 |
EP1732520B1 (en) | 2009-06-24 |
IL178018A (en) | 2010-05-17 |
PE20060127A1 (es) | 2006-03-15 |
US20140302115A1 (en) | 2014-10-09 |
CN100531800C (zh) | 2009-08-26 |
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