DE60105448D1 - Feste dispersionen mit nitrataktiven wirkstoffen - Google Patents

Feste dispersionen mit nitrataktiven wirkstoffen

Info

Publication number
DE60105448D1
DE60105448D1 DE60105448T DE60105448T DE60105448D1 DE 60105448 D1 DE60105448 D1 DE 60105448D1 DE 60105448 T DE60105448 T DE 60105448T DE 60105448 T DE60105448 T DE 60105448T DE 60105448 D1 DE60105448 D1 DE 60105448D1
Authority
DE
Germany
Prior art keywords
nitrative
active ingredients
solid dispersions
dispersions
solid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60105448T
Other languages
English (en)
Other versions
DE60105448T2 (de
Inventor
Laura Trespidi
Soldato Piero Del
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nicox SA
Original Assignee
Nicox SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox SA filed Critical Nicox SA
Publication of DE60105448D1 publication Critical patent/DE60105448D1/de
Application granted granted Critical
Publication of DE60105448T2 publication Critical patent/DE60105448T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Saccharide Compounds (AREA)
DE60105448T 2000-12-22 2001-12-18 Feste dispersionen mit nitrataktiven wirkstoffen Expired - Fee Related DE60105448T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT2000MI002803A IT1320176B1 (it) 2000-12-22 2000-12-22 Dispersioni solide di principi attivi nitrati.
ITMI20002803 2000-12-22
PCT/EP2001/014967 WO2002051385A1 (en) 2000-12-22 2001-12-18 Solid dispersions of nitrate active principles

Publications (2)

Publication Number Publication Date
DE60105448D1 true DE60105448D1 (de) 2004-10-14
DE60105448T2 DE60105448T2 (de) 2005-09-22

Family

ID=11446305

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60105448T Expired - Fee Related DE60105448T2 (de) 2000-12-22 2001-12-18 Feste dispersionen mit nitrataktiven wirkstoffen

Country Status (8)

Country Link
US (1) US20040071777A1 (de)
EP (2) EP1496064A1 (de)
JP (1) JP2004516303A (de)
AT (1) ATE275393T1 (de)
DE (1) DE60105448T2 (de)
ES (1) ES2228983T3 (de)
IT (1) IT1320176B1 (de)
WO (1) WO2002051385A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
WO2002087508A2 (en) 2001-05-02 2002-11-07 Nitromed, Inc. Nitrosated and nitrosylated nebivolol and its metabolites, compositions and methods of use
ITMI20020148A1 (it) * 2002-01-29 2003-07-29 Nicox Sa Nuovi corticosteroidi
AU2003211617C1 (en) 2002-02-28 2008-03-06 Japan Tobacco Inc. Ester compound and medicinal use thereof
JP2006501161A (ja) 2002-06-11 2006-01-12 ニトロメッド インク． ニトロソ化および／またはニトロシル化シクロオキシゲナーゼ−２選択的阻害剤、組成物ならびに使用方法
JP2005539089A (ja) 2002-07-03 2005-12-22 ニトロメッド インコーポレーティッド ニトロソ化非ステロイド性抗炎症化合物、組成物および使用方法
US7244753B2 (en) 2002-07-29 2007-07-17 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
JP4634144B2 (ja) 2002-08-01 2011-02-16 ニコックス エスエー ニトロソ化プロトンポンプ阻害剤、組成物および使用方法
WO2004105728A2 (en) * 2003-05-27 2004-12-09 Ranbaxy Laboratories Limited Solid dispersions of cefpodoxime proxetil and processes for their preparation
US7790197B2 (en) 2003-06-09 2010-09-07 Warner-Lambert Company Llc Pharmaceutical compositions of atorvastatin
US7655692B2 (en) 2003-06-12 2010-02-02 Pfizer Inc. Process for forming amorphous atorvastatin
JP4832897B2 (ja) 2003-08-29 2011-12-07 日本たばこ産業株式会社 エステル誘導体及びその医薬用途
KR20080064209A (ko) * 2003-12-04 2008-07-08 화이자 프로덕츠 인코포레이티드 바람직하게는 폴록사머와 글리세라이드를 함유하는다미립자 아지트로마이신 조성물의 제조를 위해 압출기를사용하는 분무응결 방법
CA2554716A1 (en) * 2004-01-22 2005-08-04 Nitromed, Inc. Nitrosated and/or nitrosylated compounds, compositions and methods of use
US7838552B2 (en) 2004-06-04 2010-11-23 Forest Laboratories Holdings Limited Compositions comprising nebivolol
US7803838B2 (en) 2004-06-04 2010-09-28 Forest Laboratories Holdings Limited Compositions comprising nebivolol
US8101774B2 (en) 2004-10-18 2012-01-24 Japan Tobacco Inc. Ester derivatives and medicinal use thereof
US20060160871A1 (en) * 2004-12-07 2006-07-20 Nektar Therapeutics Stable non-crystalline formulation comprising losartan
JP5256739B2 (ja) * 2004-12-30 2013-08-07 ピエール・ファーブル・メディカマン ビンカアルカロイド誘導体の安定固体分散体とその製造方法
US9089544B2 (en) * 2007-08-24 2015-07-28 Slotervaart Participaties Bv Composition
JP2011513301A (ja) * 2008-02-28 2011-04-28 バイアル−ポルテラ アンド シーエー，エス．エー． 難溶性薬剤のための医薬組成物
EA201071058A1 (ru) * 2008-03-11 2011-02-28 Др. Редди'С Лабораторис Лтд. Получение леналидомида
KR101037808B1 (ko) * 2008-07-02 2011-05-30 한국콜마 주식회사 가용화된 니플루믹산을 함유하는 서방성 정제
CN113274355B (zh) * 2009-10-27 2023-05-30 鲁平有限公司 利福昔明固体分散体
CA2792273A1 (en) * 2010-03-08 2011-09-15 Ratiopharm Gmbh Dabigatran etexilate-containing pharmaceutical composition
EA033370B1 (ru) 2010-07-12 2019-10-31 Salix Pharmaceuticals Ltd Составы рифаксимина и их применение
RS63751B1 (sr) 2016-09-30 2022-12-30 Salix Pharmaceuticals Inc Čvrsti disperzioni oblici rifaksimina
CN110193013B (zh) * 2019-07-02 2022-02-08 力品药业(厦门)股份有限公司 一种去乙酰真菌环氧乙酯固体分散体及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1256450B (it) * 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
US5837698A (en) * 1996-05-02 1998-11-17 G. D. Searle & Co. Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs
US5985862A (en) * 1996-05-02 1999-11-16 G.D. Searle & Co. Pharmaceutical compositions having steroid nitrate ester derivatives useful as anti-inflammatory drugs
IT1285770B1 (it) * 1996-10-04 1998-06-18 Nicox Sa Composti corticoidei
US6706283B1 (en) * 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
IT1311922B1 (it) * 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
AU6917400A (en) * 1999-08-31 2001-03-26 Alcon Laboratories, Inc. Use of 5-ht1b/1d agonists to treat otic pain
EP1429739A1 (de) * 2001-09-21 2004-06-23 Egalet A/S Polymer-freigabe-system

Also Published As

Publication number Publication date
WO2002051385A8 (en) 2002-10-31
IT1320176B1 (it) 2003-11-26
EP1347744A1 (de) 2003-10-01
JP2004516303A (ja) 2004-06-03
ITMI20002803A1 (it) 2002-06-22
ATE275393T1 (de) 2004-09-15
WO2002051385A1 (en) 2002-07-04
ES2228983T3 (es) 2005-04-16
DE60105448T2 (de) 2005-09-22
EP1496064A1 (de) 2005-01-12
EP1347744B1 (de) 2004-09-08
US20040071777A1 (en) 2004-04-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NICOX S.A., SOPHIA ANTIPOLIS, FR

8339 Ceased/non-payment of the annual fee