BRPI0306143B8 - processo para produção de grânulos ou pós, adequados como agentes de revestimento e aglutinantes para formas farmacêuticas, orais ou dérmicas, para cosméticos ou suplementos alimentares - Google Patents
processo para produção de grânulos ou pós, adequados como agentes de revestimento e aglutinantes para formas farmacêuticas, orais ou dérmicas, para cosméticos ou suplementos alimentaresInfo
- Publication number
- BRPI0306143B8 BRPI0306143B8 BRPI0306143A BR0306143A BRPI0306143B8 BR PI0306143 B8 BRPI0306143 B8 BR PI0306143B8 BR PI0306143 A BRPI0306143 A BR PI0306143A BR 0306143 A BR0306143 A BR 0306143A BR PI0306143 B8 BRPI0306143 B8 BR PI0306143B8
- Authority
- BR
- Brazil
- Prior art keywords
- granules
- binders
- powders
- production
- coating agents
- Prior art date
Links
- 239000008187 granular material Substances 0.000 title abstract 4
- 239000000843 powder Substances 0.000 title abstract 4
- 239000011230 binding agent Substances 0.000 title abstract 3
- 239000011248 coating agent Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 239000002537 cosmetic Substances 0.000 title abstract 2
- 235000015872 dietary supplement Nutrition 0.000 title abstract 2
- 230000002500 effect on skin Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000005397 methacrylic acid ester group Chemical group 0.000 abstract 1
- 150000002762 monocarboxylic acid derivatives Chemical class 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 125000001302 tertiary amino group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- General Preparation And Processing Of Foods (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10239999A DE10239999A1 (de) | 2002-08-27 | 2002-08-27 | Granulat oder Pulver zur Herstellung von Überzugs- und Bindemitteln für Arzneiformen |
| PCT/EP2003/007319 WO2004019918A1 (de) | 2002-08-27 | 2003-07-08 | Granulat oder pulver zur herstellung von überzugs- und bindemitteln für arzneiformen |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR0306143A BR0306143A (pt) | 2004-10-19 |
| BRPI0306143B1 BRPI0306143B1 (pt) | 2016-03-08 |
| BRPI0306143B8 true BRPI0306143B8 (pt) | 2021-05-25 |
Family
ID=31197526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0306143A BRPI0306143B8 (pt) | 2002-08-27 | 2003-07-08 | processo para produção de grânulos ou pós, adequados como agentes de revestimento e aglutinantes para formas farmacêuticas, orais ou dérmicas, para cosméticos ou suplementos alimentares |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7175857B2 (enExample) |
| EP (1) | EP1432409B1 (enExample) |
| JP (1) | JP4571861B2 (enExample) |
| KR (1) | KR100942667B1 (enExample) |
| AT (1) | ATE408401T1 (enExample) |
| AU (1) | AU2003266232A1 (enExample) |
| BR (1) | BRPI0306143B8 (enExample) |
| CA (1) | CA2464502C (enExample) |
| DE (2) | DE10239999A1 (enExample) |
| ES (1) | ES2314275T3 (enExample) |
| IL (2) | IL161145A0 (enExample) |
| IN (1) | IN2004CH00875A (enExample) |
| MX (1) | MX250472B (enExample) |
| PL (1) | PL206233B1 (enExample) |
| SI (1) | SI1432409T1 (enExample) |
| WO (1) | WO2004019918A1 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10208344A1 (de) | 2002-02-27 | 2003-09-04 | Roehm Gmbh | Schmelzextrusion von Wirkstoffsalzen |
| DE10260920A1 (de) * | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von Arnzeiformen oder Nahrungsergänzungsmitteln mit pigmentierten Polymerüberzügen |
| DE10260919A1 (de) * | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von überzogenen Arzneiformen und Nahrungsergänzungsmitteln mit Konzentrationsgradienten im Überzug |
| DE10260921A1 (de) * | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zum Überziehen von Substraten für pharmazeutische Anwendungen mit einem Gemisch aus zwei filmbildenden Überzugsmitteln |
| DE10304403A1 (de) | 2003-01-28 | 2004-08-05 | Röhm GmbH & Co. KG | Verfahren zur Herstellung einer oralen Arzneiform mit unmittelbarem Zerfall und Wirkstofffreisetzung |
| DE102004029573A1 (de) * | 2004-06-18 | 2005-12-29 | Gambro Lundia Ab | MIF-Adsorbent |
| WO2006046560A1 (ja) * | 2004-10-29 | 2006-05-04 | Taiho Pharmaceutical Co., Ltd. | プロピベリン含有経口粉粒状製剤及びその製造法 |
| EP1681049A1 (fr) * | 2005-01-12 | 2006-07-19 | Physica Pharma | Composition pharmaceutique et forme galénique correspondante à délitement rapide en bouche, et procédé de fabrication de cette composition |
| US20060264458A1 (en) * | 2005-05-03 | 2006-11-23 | Jie Du | Quinine dosage forms and methods of use thereof |
| DE102005042039A1 (de) * | 2005-09-02 | 2007-03-08 | Basf Ag | Wässrige Polyvinylacetatdispersionen mit hoher Scherstabilität |
| ATE462416T1 (de) * | 2006-08-04 | 2010-04-15 | Ethypharm Sa | Mehrschichtige im mund zerfallende tablette |
| EP2176301B1 (de) | 2007-08-02 | 2013-05-15 | Basf Se | Wässrige polymerdispersion auf basis von n, n-diethylaminoethylmethacrylat, deren herstellung und verwendung |
| US20100062062A1 (en) * | 2008-09-11 | 2010-03-11 | Aethos Pharmaceuticals, Inc. | Stabilized Coating for Pharmaceutical Formulations |
| US9254329B2 (en) | 2009-10-28 | 2016-02-09 | Basf Se | Stable protective coatings for pharmaceutical dosage forms |
| US20110150986A1 (en) * | 2009-12-18 | 2011-06-23 | Kristin Arnold | Quinine formulations, method of making, and metho of use thereof |
| AU2011226324B2 (en) * | 2010-03-10 | 2015-09-24 | Nogra Pharma Limited | Compositions for colon lavage and methods of making and using same |
| CN102985074B (zh) * | 2010-05-10 | 2015-09-02 | 赢创罗姆有限公司 | 包含一种或多种抗逆转录病毒活性成分的药物剂型 |
| EP2613770A1 (de) | 2010-09-07 | 2013-07-17 | Basf Se | Verwendung von copolymeren auf basis von aminogruppenhaltigen polymeren als matrixbindemittel für die herstellung von wirkstoffhaltigen granulaten und darreichungsformen |
| WO2012041788A1 (de) | 2010-09-27 | 2012-04-05 | Basf Se | Protektive überzüge für saure wirkstoffe |
| US9795576B2 (en) | 2010-09-27 | 2017-10-24 | Basf Se | Protective coatings for acidic active ingredients |
| US8865250B2 (en) | 2011-02-28 | 2014-10-21 | Basf Se | Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms |
| JP6027550B2 (ja) | 2011-02-28 | 2016-11-16 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | 医薬剤形用の安定した保護被覆のための粉末被覆剤の製造 |
| CN103403069B (zh) | 2011-02-28 | 2017-06-13 | 巴斯夫欧洲公司 | 制备用于药物剂型的稳定保护涂层的粉末涂覆剂的方法 |
| US8962064B2 (en) | 2011-02-28 | 2015-02-24 | Basf Se | Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms |
| US9044734B2 (en) | 2011-09-23 | 2015-06-02 | Basf Se | Diesel oxidation catalyst with layered structure containing ceria composition as palladium support material for enhanced HC and CO gas conversion |
| EP2636403A1 (de) * | 2012-03-09 | 2013-09-11 | Basf Se | Herstellung von pharmazeutischen protektiven Überzügen mit guter Resistenz im neutralen Milieu |
| US20130236505A1 (en) | 2012-03-09 | 2013-09-12 | Basf Se | Production Of Pharmaceutical Protective Coatings With Good Resistance In A Neutral Environment |
| US10668156B2 (en) | 2012-06-22 | 2020-06-02 | Basf Se | Active-ingredient-containing solid dispersions based on diethylaminoethyl methacrylate copolymers |
| JP6189429B2 (ja) | 2012-06-22 | 2017-08-30 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | ジエチルアミノエチルメタクリレートコポリマーをベースにした活性成分含有固体分散体 |
| CA2892023A1 (en) * | 2012-11-22 | 2014-05-30 | Evonik Rohm Gmbh | Process for preparing a granulated product from a powder composition |
| FR3027802B1 (fr) * | 2014-10-31 | 2018-03-02 | Ethypharm | Granules de principe actif a double masquage de gout, leur procede de preparation et comprimes orodispersibles les contenant |
| GR1008992B (el) * | 2015-12-17 | 2017-03-23 | Verisfield (Uk) Ltd, Υποκαταστημα Ελλαδας, Εμπορια Φαρμακων | Φαρμακευτικη συνθεση σε μορφη κοκκιων για χορηγηση απο το στομα που περιεχει μετρονιδαζολη ή παραγωγα αυτης και εναν παραγοντα καλυψης της γευσης |
| EP3569225A1 (en) * | 2018-05-18 | 2019-11-20 | Pharmaceutical Oriented Services Ltd | Solid dispersion containing ritonavir |
| TWI829841B (zh) * | 2018-12-27 | 2024-01-21 | 日商興和股份有限公司 | 醫藥品 |
| JP2023553010A (ja) | 2020-12-03 | 2023-12-20 | バテル・メモリアル・インスティテュート | 非ウイルス性送達のためのポリマーナノ粒子およびｄｎａナノ構造組成物ならびに方法 |
| EP4320233A4 (en) | 2021-04-07 | 2025-08-13 | Battelle Memorial Institute | RAPID DESIGN, BUILD, TEST, AND LEARNING TECHNOLOGIES TO IDENTIFY AND USE NON-VIRAL VECTORS |
| WO2025072751A1 (en) | 2023-09-29 | 2025-04-03 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| WO2025122954A1 (en) | 2023-12-08 | 2025-06-12 | Battelle Memorial Institute | Use of dna origami nanostructures for molecular information based data storage systems |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0164669B1 (de) | 1984-06-13 | 1991-01-23 | Röhm Gmbh | Verfahren zum Überziehen von Arzneiformen |
| DE3920082A1 (de) | 1989-06-20 | 1991-03-07 | Roehm Gmbh | Filmbildendes waessriges ueberzugsmittel fuer feste arzneimittel, verfahren zu seiner herstellung und verwendung |
| DE29502547U1 (de) | 1995-02-16 | 1995-03-30 | Röhm GmbH, 64293 Darmstadt | Thermoplastisches Überzugs- und Bindemittel für Arzneiformen |
| DE19918435A1 (de) * | 1998-07-23 | 2000-01-27 | Roehm Gmbh | Überzugs- und Bindemittel für orale oder dermale Arzneiformen |
| DE19958007A1 (de) * | 1999-12-02 | 2001-06-07 | Roehm Gmbh | Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen |
| EP1311820B1 (en) * | 2000-07-14 | 2015-02-11 | Janssen Diagnostics, LLC | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
| CA2403831C (en) * | 2001-02-27 | 2009-11-24 | Evonik Operations Gmbh | Coating and binding agent for pharmaceutical formulations having improved storage stability |
| DE10208344A1 (de) * | 2002-02-27 | 2003-09-04 | Roehm Gmbh | Schmelzextrusion von Wirkstoffsalzen |
-
2002
- 2002-08-27 DE DE10239999A patent/DE10239999A1/de not_active Withdrawn
-
2003
- 2003-07-08 US US10/489,856 patent/US7175857B2/en not_active Expired - Lifetime
- 2003-07-08 EP EP03790791A patent/EP1432409B1/de not_active Expired - Lifetime
- 2003-07-08 SI SI200331454T patent/SI1432409T1/sl unknown
- 2003-07-08 IL IL16114503A patent/IL161145A0/xx unknown
- 2003-07-08 JP JP2004531794A patent/JP4571861B2/ja not_active Expired - Lifetime
- 2003-07-08 WO PCT/EP2003/007319 patent/WO2004019918A1/de not_active Ceased
- 2003-07-08 ES ES03790791T patent/ES2314275T3/es not_active Expired - Lifetime
- 2003-07-08 CA CA2464502A patent/CA2464502C/en not_active Expired - Lifetime
- 2003-07-08 BR BRPI0306143A patent/BRPI0306143B8/pt active IP Right Grant
- 2003-07-08 PL PL368186A patent/PL206233B1/pl unknown
- 2003-07-08 MX MXPA04003970 patent/MX250472B/es active IP Right Grant
- 2003-07-08 DE DE50310506T patent/DE50310506D1/de not_active Expired - Lifetime
- 2003-07-08 AT AT03790791T patent/ATE408401T1/de active
- 2003-07-08 AU AU2003266232A patent/AU2003266232A1/en not_active Abandoned
-
2004
- 2004-03-29 IL IL161145A patent/IL161145A/en active IP Right Grant
- 2004-04-26 IN IN875CH2004 patent/IN2004CH00875A/en unknown
- 2004-04-27 KR KR20047006270A patent/KR100942667B1/ko not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR100942667B1 (ko) | 2010-02-17 |
| AU2003266232A1 (en) | 2004-03-19 |
| JP2005536555A (ja) | 2005-12-02 |
| ES2314275T3 (es) | 2009-03-16 |
| CA2464502A1 (en) | 2004-03-11 |
| MXPA04003970A (es) | 2004-06-22 |
| US20050197434A9 (en) | 2005-09-08 |
| BRPI0306143B1 (pt) | 2016-03-08 |
| DE50310506D1 (de) | 2008-10-30 |
| IL161145A (en) | 2010-11-30 |
| EP1432409B1 (de) | 2008-09-17 |
| US7175857B2 (en) | 2007-02-13 |
| SI1432409T1 (sl) | 2009-02-28 |
| IN2004CH00875A (enExample) | 2006-01-13 |
| US20040249035A1 (en) | 2004-12-09 |
| EP1432409A1 (de) | 2004-06-30 |
| BR0306143A (pt) | 2004-10-19 |
| PL368186A1 (en) | 2005-03-21 |
| WO2004019918A1 (de) | 2004-03-11 |
| MX250472B (es) | 2007-10-17 |
| PL206233B1 (pl) | 2010-07-30 |
| KR20050034620A (ko) | 2005-04-14 |
| IL161145A0 (en) | 2004-08-31 |
| DE10239999A1 (de) | 2004-03-04 |
| JP4571861B2 (ja) | 2010-10-27 |
| CA2464502C (en) | 2010-11-23 |
| ATE408401T1 (de) | 2008-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B25D | Requested change of name of applicant approved |
Owner name: ROEHM GMBH (DE) Free format text: NOME ALTERADO DE: ROEEHM GMBH AND CO. KG |
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