KR100942667B1 - 약제학적 제형용 피복제 또는 결합제로서 적합한 과립 또는 분말 및 이의 제조방법 - Google Patents
약제학적 제형용 피복제 또는 결합제로서 적합한 과립 또는 분말 및 이의 제조방법 Download PDFInfo
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- KR100942667B1 KR100942667B1 KR20047006270A KR20047006270A KR100942667B1 KR 100942667 B1 KR100942667 B1 KR 100942667B1 KR 20047006270 A KR20047006270 A KR 20047006270A KR 20047006270 A KR20047006270 A KR 20047006270A KR 100942667 B1 KR100942667 B1 KR 100942667B1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- General Preparation And Processing Of Foods (AREA)
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| DE10239999.9 | 2002-08-27 | ||
| DE10239999A DE10239999A1 (de) | 2002-08-27 | 2002-08-27 | Granulat oder Pulver zur Herstellung von Überzugs- und Bindemitteln für Arzneiformen |
Publications (2)
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| KR20050034620A KR20050034620A (ko) | 2005-04-14 |
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| PL (1) | PL206233B1 (enExample) |
| SI (1) | SI1432409T1 (enExample) |
| WO (1) | WO2004019918A1 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10208344A1 (de) | 2002-02-27 | 2003-09-04 | Roehm Gmbh | Schmelzextrusion von Wirkstoffsalzen |
| DE10260921A1 (de) * | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zum Überziehen von Substraten für pharmazeutische Anwendungen mit einem Gemisch aus zwei filmbildenden Überzugsmitteln |
| DE10260919A1 (de) * | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von überzogenen Arzneiformen und Nahrungsergänzungsmitteln mit Konzentrationsgradienten im Überzug |
| DE10260920A1 (de) * | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von Arnzeiformen oder Nahrungsergänzungsmitteln mit pigmentierten Polymerüberzügen |
| DE10304403A1 (de) * | 2003-01-28 | 2004-08-05 | Röhm GmbH & Co. KG | Verfahren zur Herstellung einer oralen Arzneiform mit unmittelbarem Zerfall und Wirkstofffreisetzung |
| DE102004029573A1 (de) * | 2004-06-18 | 2005-12-29 | Gambro Lundia Ab | MIF-Adsorbent |
| JP4895819B2 (ja) * | 2004-10-29 | 2012-03-14 | 大鵬薬品工業株式会社 | プロピベリン含有経口粉粒状製剤及びその製造法 |
| EP1681049A1 (fr) * | 2005-01-12 | 2006-07-19 | Physica Pharma | Composition pharmaceutique et forme galénique correspondante à délitement rapide en bouche, et procédé de fabrication de cette composition |
| US20060263427A1 (en) * | 2005-05-03 | 2006-11-23 | Roberts Richard H | Quinine formulations |
| DE102005042039A1 (de) * | 2005-09-02 | 2007-03-08 | Basf Ag | Wässrige Polyvinylacetatdispersionen mit hoher Scherstabilität |
| KR101408315B1 (ko) * | 2006-08-04 | 2014-06-20 | 에씨팜 | 다층 경구 붕해 정제 |
| US8790693B2 (en) * | 2007-08-02 | 2014-07-29 | Basf Se | Aqueous polymer dispersion based on N,N-diethylaminoethyl methacrylate, its preparation and use |
| WO2010030735A2 (en) * | 2008-09-11 | 2010-03-18 | Aethos Pharmaceuticals, Inc. | Stabilized coating for pharmaceutical formulations |
| US9254329B2 (en) | 2009-10-28 | 2016-02-09 | Basf Se | Stable protective coatings for pharmaceutical dosage forms |
| US20110150986A1 (en) * | 2009-12-18 | 2011-06-23 | Kristin Arnold | Quinine formulations, method of making, and metho of use thereof |
| EP2544723A2 (en) * | 2010-03-10 | 2013-01-16 | Giuliani International Limited | Compositions for colon lavage and methods of making and using same |
| CA2799110A1 (en) * | 2010-05-10 | 2011-11-17 | Evonik Roehm Gmbh | Pharmaceutical dosage form comprising one or more antiretroviral active ingredients |
| JP2013536821A (ja) | 2010-09-07 | 2013-09-26 | ビーエーエスエフ ソシエタス・ヨーロピア | 活性化合物含有顆粒及び投与剤形の調製における、アミノ含有ポリマーに基づくコポリマーのマトリックス結合剤としての使用 |
| US9795576B2 (en) | 2010-09-27 | 2017-10-24 | Basf Se | Protective coatings for acidic active ingredients |
| WO2012041788A1 (de) | 2010-09-27 | 2012-04-05 | Basf Se | Protektive überzüge für saure wirkstoffe |
| EP2681263B1 (de) | 2011-02-28 | 2018-09-12 | Basf Se | Herstellung von pulverförmigen überzugsmitteln für stabile protektive überzüge für pharmazeutische dosierungsformen |
| EP2681264B1 (de) | 2011-02-28 | 2017-08-02 | Basf Se | Herstellung von pulverförmigen überzugsmitteln für stabile protektive überzüge für pharmazeutische dosierungsformen |
| US8865250B2 (en) | 2011-02-28 | 2014-10-21 | Basf Se | Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms |
| US8962064B2 (en) | 2011-02-28 | 2015-02-24 | Basf Se | Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms |
| US9044734B2 (en) | 2011-09-23 | 2015-06-02 | Basf Se | Diesel oxidation catalyst with layered structure containing ceria composition as palladium support material for enhanced HC and CO gas conversion |
| EP2636403A1 (de) * | 2012-03-09 | 2013-09-11 | Basf Se | Herstellung von pharmazeutischen protektiven Überzügen mit guter Resistenz im neutralen Milieu |
| US20130236505A1 (en) | 2012-03-09 | 2013-09-12 | Basf Se | Production Of Pharmaceutical Protective Coatings With Good Resistance In A Neutral Environment |
| CN104379174B (zh) | 2012-06-22 | 2018-01-26 | 巴斯夫欧洲公司 | 基于甲基丙烯酸二乙基氨基乙酯共聚物的含活性成分固体分散体 |
| US10668156B2 (en) | 2012-06-22 | 2020-06-02 | Basf Se | Active-ingredient-containing solid dispersions based on diethylaminoethyl methacrylate copolymers |
| WO2014079592A1 (en) * | 2012-11-22 | 2014-05-30 | Evonik Industries Ag | Process for preparing a granulated product from a powder composition |
| FR3027802B1 (fr) * | 2014-10-31 | 2018-03-02 | Ethypharm | Granules de principe actif a double masquage de gout, leur procede de preparation et comprimes orodispersibles les contenant |
| GR1008992B (el) * | 2015-12-17 | 2017-03-23 | Verisfield (Uk) Ltd, Υποκαταστημα Ελλαδας, Εμπορια Φαρμακων | Φαρμακευτικη συνθεση σε μορφη κοκκιων για χορηγηση απο το στομα που περιεχει μετρονιδαζολη ή παραγωγα αυτης και εναν παραγοντα καλυψης της γευσης |
| EP3569225A1 (en) * | 2018-05-18 | 2019-11-20 | Pharmaceutical Oriented Services Ltd | Solid dispersion containing ritonavir |
| JP7058763B2 (ja) * | 2018-12-27 | 2022-04-22 | 興和株式会社 | 医薬品 |
| US20220175812A1 (en) | 2020-12-03 | 2022-06-09 | Battelle Memorial Institute | Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery |
| JP2024516108A (ja) | 2021-04-07 | 2024-04-12 | バテル・メモリアル・インスティテュート | 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術 |
| WO2025072751A1 (en) | 2023-09-29 | 2025-04-03 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| US12441996B2 (en) | 2023-12-08 | 2025-10-14 | Battelle Memorial Institute | Use of DNA origami nanostructures for molecular information based data storage systems |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002067906A1 (de) * | 2001-02-27 | 2002-09-06 | Röhm GmbH & Co. KG | Überzugs- und bindemittel für arzneimittelformulierungen mit verbesserter lagerstabilität |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0164669B1 (de) | 1984-06-13 | 1991-01-23 | Röhm Gmbh | Verfahren zum Überziehen von Arzneiformen |
| DE3920082A1 (de) | 1989-06-20 | 1991-03-07 | Roehm Gmbh | Filmbildendes waessriges ueberzugsmittel fuer feste arzneimittel, verfahren zu seiner herstellung und verwendung |
| DE29502547U1 (de) | 1995-02-16 | 1995-03-30 | Röhm GmbH, 64293 Darmstadt | Thermoplastisches Überzugs- und Bindemittel für Arzneiformen |
| DE19918435A1 (de) | 1998-07-23 | 2000-01-27 | Roehm Gmbh | Überzugs- und Bindemittel für orale oder dermale Arzneiformen |
| DE19958007A1 (de) | 1999-12-02 | 2001-06-07 | Roehm Gmbh | Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen |
| EP1311820B1 (en) * | 2000-07-14 | 2015-02-11 | Janssen Diagnostics, LLC | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
| DE10208344A1 (de) | 2002-02-27 | 2003-09-04 | Roehm Gmbh | Schmelzextrusion von Wirkstoffsalzen |
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2002
- 2002-08-27 DE DE10239999A patent/DE10239999A1/de not_active Withdrawn
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- 2003-07-08 JP JP2004531794A patent/JP4571861B2/ja not_active Expired - Lifetime
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- 2003-07-08 US US10/489,856 patent/US7175857B2/en not_active Expired - Lifetime
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- 2004-04-27 KR KR20047006270A patent/KR100942667B1/ko not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2002067906A1 (de) * | 2001-02-27 | 2002-09-06 | Röhm GmbH & Co. KG | Überzugs- und bindemittel für arzneimittelformulierungen mit verbesserter lagerstabilität |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2464502A1 (en) | 2004-03-11 |
| PL206233B1 (pl) | 2010-07-30 |
| EP1432409B1 (de) | 2008-09-17 |
| SI1432409T1 (sl) | 2009-02-28 |
| IL161145A (en) | 2010-11-30 |
| IL161145A0 (en) | 2004-08-31 |
| WO2004019918A1 (de) | 2004-03-11 |
| PL368186A1 (en) | 2005-03-21 |
| BRPI0306143B1 (pt) | 2016-03-08 |
| MX250472B (es) | 2007-10-17 |
| ATE408401T1 (de) | 2008-10-15 |
| CA2464502C (en) | 2010-11-23 |
| AU2003266232A1 (en) | 2004-03-19 |
| JP4571861B2 (ja) | 2010-10-27 |
| JP2005536555A (ja) | 2005-12-02 |
| IN2004CH00875A (enExample) | 2006-01-13 |
| EP1432409A1 (de) | 2004-06-30 |
| ES2314275T3 (es) | 2009-03-16 |
| BRPI0306143B8 (pt) | 2021-05-25 |
| US20050197434A9 (en) | 2005-09-08 |
| US20040249035A1 (en) | 2004-12-09 |
| DE50310506D1 (de) | 2008-10-30 |
| KR20050034620A (ko) | 2005-04-14 |
| MXPA04003970A (es) | 2004-06-22 |
| BR0306143A (pt) | 2004-10-19 |
| DE10239999A1 (de) | 2004-03-04 |
| US7175857B2 (en) | 2007-02-13 |
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