ATE408401T1 - Granulat oder pulver zur herstellung von überzugs-und bindemitteln für arzneiformen - Google Patents

Granulat oder pulver zur herstellung von überzugs-und bindemitteln für arzneiformen

Info

Publication number
ATE408401T1
ATE408401T1 AT03790791T AT03790791T ATE408401T1 AT E408401 T1 ATE408401 T1 AT E408401T1 AT 03790791 T AT03790791 T AT 03790791T AT 03790791 T AT03790791 T AT 03790791T AT E408401 T1 ATE408401 T1 AT E408401T1
Authority
AT
Austria
Prior art keywords
sub
granules
powder
powders
mixed
Prior art date
Application number
AT03790791T
Other languages
German (de)
English (en)
Inventor
Hans-Ulrich Petereit
Christian Meier
Erna Roth
Andreas Gryczke
Original Assignee
Evonik Roehm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Roehm Gmbh filed Critical Evonik Roehm Gmbh
Application granted granted Critical
Publication of ATE408401T1 publication Critical patent/ATE408401T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)
AT03790791T 2002-08-27 2003-07-08 Granulat oder pulver zur herstellung von überzugs-und bindemitteln für arzneiformen ATE408401T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10239999A DE10239999A1 (de) 2002-08-27 2002-08-27 Granulat oder Pulver zur Herstellung von Überzugs- und Bindemitteln für Arzneiformen

Publications (1)

Publication Number Publication Date
ATE408401T1 true ATE408401T1 (de) 2008-10-15

Family

ID=31197526

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03790791T ATE408401T1 (de) 2002-08-27 2003-07-08 Granulat oder pulver zur herstellung von überzugs-und bindemitteln für arzneiformen

Country Status (16)

Country Link
US (1) US7175857B2 (enExample)
EP (1) EP1432409B1 (enExample)
JP (1) JP4571861B2 (enExample)
KR (1) KR100942667B1 (enExample)
AT (1) ATE408401T1 (enExample)
AU (1) AU2003266232A1 (enExample)
BR (1) BRPI0306143B8 (enExample)
CA (1) CA2464502C (enExample)
DE (2) DE10239999A1 (enExample)
ES (1) ES2314275T3 (enExample)
IL (2) IL161145A0 (enExample)
IN (1) IN2004CH00875A (enExample)
MX (1) MX250472B (enExample)
PL (1) PL206233B1 (enExample)
SI (1) SI1432409T1 (enExample)
WO (1) WO2004019918A1 (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
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DE10208344A1 (de) 2002-02-27 2003-09-04 Roehm Gmbh Schmelzextrusion von Wirkstoffsalzen
DE10260921A1 (de) * 2002-12-20 2004-07-01 Röhm GmbH & Co. KG Verfahren zum Überziehen von Substraten für pharmazeutische Anwendungen mit einem Gemisch aus zwei filmbildenden Überzugsmitteln
DE10260919A1 (de) * 2002-12-20 2004-07-01 Röhm GmbH & Co. KG Verfahren zur Herstellung von überzogenen Arzneiformen und Nahrungsergänzungsmitteln mit Konzentrationsgradienten im Überzug
DE10260920A1 (de) * 2002-12-20 2004-07-01 Röhm GmbH & Co. KG Verfahren zur Herstellung von Arnzeiformen oder Nahrungsergänzungsmitteln mit pigmentierten Polymerüberzügen
DE10304403A1 (de) * 2003-01-28 2004-08-05 Röhm GmbH & Co. KG Verfahren zur Herstellung einer oralen Arzneiform mit unmittelbarem Zerfall und Wirkstofffreisetzung
DE102004029573A1 (de) * 2004-06-18 2005-12-29 Gambro Lundia Ab MIF-Adsorbent
JP4895819B2 (ja) * 2004-10-29 2012-03-14 大鵬薬品工業株式会社 プロピベリン含有経口粉粒状製剤及びその製造法
EP1681049A1 (fr) * 2005-01-12 2006-07-19 Physica Pharma Composition pharmaceutique et forme galénique correspondante à délitement rapide en bouche, et procédé de fabrication de cette composition
US20060263427A1 (en) * 2005-05-03 2006-11-23 Roberts Richard H Quinine formulations
DE102005042039A1 (de) * 2005-09-02 2007-03-08 Basf Ag Wässrige Polyvinylacetatdispersionen mit hoher Scherstabilität
KR101408315B1 (ko) * 2006-08-04 2014-06-20 에씨팜 다층 경구 붕해 정제
US8790693B2 (en) * 2007-08-02 2014-07-29 Basf Se Aqueous polymer dispersion based on N,N-diethylaminoethyl methacrylate, its preparation and use
WO2010030735A2 (en) * 2008-09-11 2010-03-18 Aethos Pharmaceuticals, Inc. Stabilized coating for pharmaceutical formulations
US9254329B2 (en) 2009-10-28 2016-02-09 Basf Se Stable protective coatings for pharmaceutical dosage forms
US20110150986A1 (en) * 2009-12-18 2011-06-23 Kristin Arnold Quinine formulations, method of making, and metho of use thereof
EP2544723A2 (en) * 2010-03-10 2013-01-16 Giuliani International Limited Compositions for colon lavage and methods of making and using same
CA2799110A1 (en) * 2010-05-10 2011-11-17 Evonik Roehm Gmbh Pharmaceutical dosage form comprising one or more antiretroviral active ingredients
JP2013536821A (ja) 2010-09-07 2013-09-26 ビーエーエスエフ ソシエタス・ヨーロピア 活性化合物含有顆粒及び投与剤形の調製における、アミノ含有ポリマーに基づくコポリマーのマトリックス結合剤としての使用
US9795576B2 (en) 2010-09-27 2017-10-24 Basf Se Protective coatings for acidic active ingredients
WO2012041788A1 (de) 2010-09-27 2012-04-05 Basf Se Protektive überzüge für saure wirkstoffe
EP2681263B1 (de) 2011-02-28 2018-09-12 Basf Se Herstellung von pulverförmigen überzugsmitteln für stabile protektive überzüge für pharmazeutische dosierungsformen
EP2681264B1 (de) 2011-02-28 2017-08-02 Basf Se Herstellung von pulverförmigen überzugsmitteln für stabile protektive überzüge für pharmazeutische dosierungsformen
US8865250B2 (en) 2011-02-28 2014-10-21 Basf Se Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms
US8962064B2 (en) 2011-02-28 2015-02-24 Basf Se Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms
US9044734B2 (en) 2011-09-23 2015-06-02 Basf Se Diesel oxidation catalyst with layered structure containing ceria composition as palladium support material for enhanced HC and CO gas conversion
EP2636403A1 (de) * 2012-03-09 2013-09-11 Basf Se Herstellung von pharmazeutischen protektiven Überzügen mit guter Resistenz im neutralen Milieu
US20130236505A1 (en) 2012-03-09 2013-09-12 Basf Se Production Of Pharmaceutical Protective Coatings With Good Resistance In A Neutral Environment
CN104379174B (zh) 2012-06-22 2018-01-26 巴斯夫欧洲公司 基于甲基丙烯酸二乙基氨基乙酯共聚物的含活性成分固体分散体
US10668156B2 (en) 2012-06-22 2020-06-02 Basf Se Active-ingredient-containing solid dispersions based on diethylaminoethyl methacrylate copolymers
WO2014079592A1 (en) * 2012-11-22 2014-05-30 Evonik Industries Ag Process for preparing a granulated product from a powder composition
FR3027802B1 (fr) * 2014-10-31 2018-03-02 Ethypharm Granules de principe actif a double masquage de gout, leur procede de preparation et comprimes orodispersibles les contenant
GR1008992B (el) * 2015-12-17 2017-03-23 Verisfield (Uk) Ltd, Υποκαταστημα Ελλαδας, Εμπορια Φαρμακων Φαρμακευτικη συνθεση σε μορφη κοκκιων για χορηγηση απο το στομα που περιεχει μετρονιδαζολη ή παραγωγα αυτης και εναν παραγοντα καλυψης της γευσης
EP3569225A1 (en) * 2018-05-18 2019-11-20 Pharmaceutical Oriented Services Ltd Solid dispersion containing ritonavir
JP7058763B2 (ja) * 2018-12-27 2022-04-22 興和株式会社 医薬品
US20220175812A1 (en) 2020-12-03 2022-06-09 Battelle Memorial Institute Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery
JP2024516108A (ja) 2021-04-07 2024-04-12 バテル・メモリアル・インスティテュート 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
US12441996B2 (en) 2023-12-08 2025-10-14 Battelle Memorial Institute Use of DNA origami nanostructures for molecular information based data storage systems

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0164669B1 (de) 1984-06-13 1991-01-23 Röhm Gmbh Verfahren zum Überziehen von Arzneiformen
DE3920082A1 (de) 1989-06-20 1991-03-07 Roehm Gmbh Filmbildendes waessriges ueberzugsmittel fuer feste arzneimittel, verfahren zu seiner herstellung und verwendung
DE29502547U1 (de) 1995-02-16 1995-03-30 Röhm GmbH, 64293 Darmstadt Thermoplastisches Überzugs- und Bindemittel für Arzneiformen
DE19918435A1 (de) 1998-07-23 2000-01-27 Roehm Gmbh Überzugs- und Bindemittel für orale oder dermale Arzneiformen
DE19958007A1 (de) 1999-12-02 2001-06-07 Roehm Gmbh Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen
EP1311820B1 (en) * 2000-07-14 2015-02-11 Janssen Diagnostics, LLC Increased separation efficiency via controlled aggregation of magnetic nanoparticles
WO2002067906A1 (de) * 2001-02-27 2002-09-06 Röhm GmbH & Co. KG Überzugs- und bindemittel für arzneimittelformulierungen mit verbesserter lagerstabilität
DE10208344A1 (de) 2002-02-27 2003-09-04 Roehm Gmbh Schmelzextrusion von Wirkstoffsalzen

Also Published As

Publication number Publication date
CA2464502A1 (en) 2004-03-11
PL206233B1 (pl) 2010-07-30
EP1432409B1 (de) 2008-09-17
SI1432409T1 (sl) 2009-02-28
IL161145A (en) 2010-11-30
IL161145A0 (en) 2004-08-31
WO2004019918A1 (de) 2004-03-11
PL368186A1 (en) 2005-03-21
BRPI0306143B1 (pt) 2016-03-08
MX250472B (es) 2007-10-17
CA2464502C (en) 2010-11-23
AU2003266232A1 (en) 2004-03-19
JP4571861B2 (ja) 2010-10-27
JP2005536555A (ja) 2005-12-02
IN2004CH00875A (enExample) 2006-01-13
EP1432409A1 (de) 2004-06-30
ES2314275T3 (es) 2009-03-16
BRPI0306143B8 (pt) 2021-05-25
US20050197434A9 (en) 2005-09-08
KR100942667B1 (ko) 2010-02-17
US20040249035A1 (en) 2004-12-09
DE50310506D1 (de) 2008-10-30
KR20050034620A (ko) 2005-04-14
MXPA04003970A (es) 2004-06-22
BR0306143A (pt) 2004-10-19
DE10239999A1 (de) 2004-03-04
US7175857B2 (en) 2007-02-13

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