BR9915110A - Comprimido de desagregação rápida aperfeiçoado - Google Patents

Comprimido de desagregação rápida aperfeiçoado

Info

Publication number
BR9915110A
BR9915110A BR9915110-3A BR9915110A BR9915110A BR 9915110 A BR9915110 A BR 9915110A BR 9915110 A BR9915110 A BR 9915110A BR 9915110 A BR9915110 A BR 9915110A
Authority
BR
Brazil
Prior art keywords
weight
tablet
agent
excipients
particles
Prior art date
Application number
BR9915110-3A
Other languages
English (en)
Inventor
Charles Chauveau
Jean-Marc Zuccarelli
Nourredine Nouri
Maryvonne Barbero
Original Assignee
Prod Ethiques Ethypharm Sa Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prod Ethiques Ethypharm Sa Lab filed Critical Prod Ethiques Ethypharm Sa Lab
Publication of BR9915110A publication Critical patent/BR9915110A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Detergent Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

Patente de Invenção: <B>"COMPRIMIDO DE DESAGREGAçãO RáPIDA APERFEIçOADO"<D>. A presente invenção tem como objeto um comprimido de partículas múltiplas aperfeiçoado que se desagrega na boca em contato com a saliva em menos de 40 segundos, caracterizado pelo fato de que ele é à base de partículas de princípio ativo revestido, as ditas partículas apresentando características intrínsecas de compressão e de uma mistura de excipientes, a proporção de mistura de excipientes em relação às partículas de princípio ativo revestido sendo de 0,4 a 6 partes em peso a mistura de excipientes compreendendo um agente de desagregação, um agente solúvel diluente de propriedades ligantes, um lubrificante, um agente permeabilizante, e vantajosamente lubrificantes, edulcorantes, aromas e corantes, a proporção de agente de desagregação e de agente solúvel em relação à massa do comprimido sendo de 1 a 15% em peso para o primeiro e de 30 a 90% em peso para o segundo.
BR9915110-3A 1998-11-06 1999-11-03 Comprimido de desagregação rápida aperfeiçoado BR9915110A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9814034A FR2785538B1 (fr) 1998-11-06 1998-11-06 Comprime a delitement rapide perfectionne
PCT/FR1999/002681 WO2000027357A1 (fr) 1998-11-06 1999-11-03 Comprime a delitement rapide perfectionne

Publications (1)

Publication Number Publication Date
BR9915110A true BR9915110A (pt) 2001-07-31

Family

ID=9532493

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9915110-3A BR9915110A (pt) 1998-11-06 1999-11-03 Comprimido de desagregação rápida aperfeiçoado

Country Status (28)

Country Link
US (2) US7067149B1 (pt)
EP (1) EP1126821B1 (pt)
JP (2) JP2002529392A (pt)
KR (1) KR100630465B1 (pt)
CN (1) CN1154476C (pt)
AT (1) ATE293954T1 (pt)
AU (1) AU767703B2 (pt)
BG (1) BG65011B1 (pt)
BR (1) BR9915110A (pt)
CA (1) CA2350054C (pt)
CZ (1) CZ301589B6 (pt)
DE (1) DE69925016T2 (pt)
DK (1) DK1126821T3 (pt)
EA (1) EA004239B1 (pt)
ES (1) ES2241334T3 (pt)
FR (1) FR2785538B1 (pt)
HK (1) HK1039891B (pt)
HU (1) HU226590B1 (pt)
IL (1) IL142788A (pt)
MX (1) MXPA01004518A (pt)
NZ (1) NZ511480A (pt)
PL (1) PL194526B1 (pt)
PT (1) PT1126821E (pt)
SI (1) SI1126821T1 (pt)
SK (1) SK284645B6 (pt)
TR (1) TR200101224T2 (pt)
WO (1) WO2000027357A1 (pt)
ZA (1) ZA200103629B (pt)

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GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
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JP5062871B2 (ja) * 2003-05-13 2012-10-31 東和薬品株式会社 苦味を低減した口腔内崩壊錠剤
FR2855756B1 (fr) * 2003-06-06 2005-08-26 Ethypharm Sa Comprime orodispersible multicouche
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FR3055800B1 (fr) 2016-09-15 2020-06-26 Unither Pharmaceuticals Composition solide a ingestion rapide et deglutition facilitee, sous forme de particules solides non agglomerees, comprenant deux differents types de particules
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US10543205B2 (en) 2016-11-18 2020-01-28 Fertin Pharma A/S Oral delivery vehicle containing nicotine
CA3002181C (en) * 2017-04-18 2020-05-05 Kashiv Pharma Llc Food independent immediate release drug formulation with abuse deterrence and overdose protection
US11052047B2 (en) * 2018-05-17 2021-07-06 Fertin Pharma A/S Oral tablet suitable for fast release of active pharmaceutical ingredients
US11096894B2 (en) 2018-05-17 2021-08-24 Fertin Pharma A/S Oral tablet for induced saliva generation
US11096896B2 (en) 2018-05-17 2021-08-24 Fertin Pharma A/S Tablet dosage form for buccal absorption of active ingredients
US11090263B2 (en) 2018-05-22 2021-08-17 Fertin Pharma A/S Tableted chewing gum suitable for active pharmaceutical ingredients
US11058641B2 (en) 2018-05-17 2021-07-13 Fertin Pharma A/S Oral tablet for taste masking of active ingredients
US11135157B2 (en) 2018-05-17 2021-10-05 Fertin Pharma A/S Oral tablet for delivery of active ingredients to the throat
US20190350858A1 (en) 2018-05-17 2019-11-21 Fertin Pharma A/S Oral tablet for delivery of active ingredients to the gastrointestinal tract
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Also Published As

Publication number Publication date
BG105475A (en) 2001-11-30
PL194526B1 (pl) 2007-06-29
DE69925016D1 (de) 2005-06-02
HK1039891B (zh) 2005-09-09
CA2350054A1 (fr) 2000-05-18
HK1039891A1 (en) 2002-05-17
US20060177508A1 (en) 2006-08-10
JP2002529392A (ja) 2002-09-10
EA200100492A1 (ru) 2001-12-24
HU226590B1 (en) 2009-04-28
KR20010090831A (ko) 2001-10-19
SK5672001A3 (en) 2001-11-06
ATE293954T1 (de) 2005-05-15
CZ301589B6 (cs) 2010-04-28
HUP0104393A2 (hu) 2002-03-28
SK284645B6 (sk) 2005-08-04
PL347550A1 (en) 2002-04-08
US7695735B2 (en) 2010-04-13
TR200101224T2 (tr) 2001-11-21
AU1050700A (en) 2000-05-29
PT1126821E (pt) 2005-08-31
AU767703B2 (en) 2003-11-20
KR100630465B1 (ko) 2006-10-02
EP1126821A1 (fr) 2001-08-29
ZA200103629B (en) 2002-05-06
US7067149B1 (en) 2006-06-27
NZ511480A (en) 2003-10-31
FR2785538B1 (fr) 2004-04-09
MXPA01004518A (es) 2003-06-09
CA2350054C (fr) 2011-05-31
CN1328446A (zh) 2001-12-26
CN1154476C (zh) 2004-06-23
SI1126821T1 (en) 2005-10-31
CZ20011433A3 (cs) 2001-09-12
FR2785538A1 (fr) 2000-05-12
BG65011B1 (bg) 2006-12-29
DE69925016T2 (de) 2006-03-02
EP1126821B1 (fr) 2005-04-27
IL142788A (en) 2006-08-01
EA004239B1 (ru) 2004-02-26
WO2000027357A1 (fr) 2000-05-18
JP2012001557A (ja) 2012-01-05
ES2241334T3 (es) 2005-10-16
HUP0104393A3 (en) 2002-12-28
DK1126821T3 (da) 2005-08-22

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