BR9912353A - Agente de revestimento e aglutinante para formas de medicamento orais e dérmicas - Google Patents

Agente de revestimento e aglutinante para formas de medicamento orais e dérmicas

Info

Publication number
BR9912353A
BR9912353A BR9912353-3A BR9912353A BR9912353A BR 9912353 A BR9912353 A BR 9912353A BR 9912353 A BR9912353 A BR 9912353A BR 9912353 A BR9912353 A BR 9912353A
Authority
BR
Brazil
Prior art keywords
coating
oral
weight
binding agent
drug forms
Prior art date
Application number
BR9912353-3A
Other languages
English (en)
Other versions
BR9912353B1 (pt
Inventor
Hans-Ulrich Petereit
Christian Meier
Erna Roth
Original Assignee
Roehm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roehm Gmbh filed Critical Roehm Gmbh
Publication of BR9912353A publication Critical patent/BR9912353A/pt
Publication of BR9912353B1 publication Critical patent/BR9912353B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S524/00—Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S524/904—Powder coating compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Paints Or Removers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Patente de Invenção: <B>"AGENTE DE REVESTIMENTO E AGLUTINANTE PARA FORMAS DE MEDICAMENTO ORAIS E DéRMICAS"<D>. A invenção refere-se a um processo para a preparação de um agente de revestimento ou aglutinante para formas de medicamento orais ou dérmicas, consistindo em (a) 35 - 98% em peso de um copolímero, consistindo em ésteres de C1 até C4, polimerizados via radicais livres, do ácido acrílico ou metacrílico e outros monómeros de (met)acrilato, que apresentam grupos amónio terciários funcionais e (b) 1 - 50% em peso de um plastificante, assim como 1 - 15% em peso de um emulsificante com um valor de HLB de pelo menos 14, sendo que os componentes (a), (b), e (c), com ou sem a adição de água e, eventualmente, sob adição de uma substância ativa farmacêutica e de outros ingredientes usuais, são misturados uns com os outros e o agente de revestimento e aglutinante é preparado por fusão, derramamento, pincelamento ou atomização, caracterizado pelo fato de que o copolímero (a) é aplicado em forma de pó com um tamanho de partícula de 1-40 Ám.
BRPI9912353-3A 1998-07-23 1999-07-02 processo para a preparação de um agente de revestimento e aglutinante para formas de medicamento orais e tópicas, agente de revestimento e aglutinante preparável por este processo, copolìmero e aplicações do referido agente de revestimento e aglutinante. BR9912353B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19833016 1998-07-23
DE19833016.2 1998-07-23
DE19918435.6 1999-04-23
DE19918435A DE19918435A1 (de) 1998-07-23 1999-04-23 Überzugs- und Bindemittel für orale oder dermale Arzneiformen
PCT/EP1999/004620 WO2000005307A1 (de) 1998-07-23 1999-07-02 Überzugs- und bindemittel für orale oder dermale arzneiformen

Publications (2)

Publication Number Publication Date
BR9912353A true BR9912353A (pt) 2001-04-17
BR9912353B1 BR9912353B1 (pt) 2012-01-24

Family

ID=26047615

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9912353-3A BR9912353B1 (pt) 1998-07-23 1999-07-02 processo para a preparação de um agente de revestimento e aglutinante para formas de medicamento orais e tópicas, agente de revestimento e aglutinante preparável por este processo, copolìmero e aplicações do referido agente de revestimento e aglutinante.

Country Status (18)

Country Link
US (2) US6624210B1 (pt)
EP (1) EP1098935B1 (pt)
JP (1) JP4636687B2 (pt)
KR (2) KR100663663B1 (pt)
CN (1) CN1142212C (pt)
AT (1) ATE230426T1 (pt)
AU (1) AU4781599A (pt)
BR (1) BR9912353B1 (pt)
CA (1) CA2338750C (pt)
DE (2) DE19918435A1 (pt)
ES (1) ES2190226T3 (pt)
HK (1) HK1041014B (pt)
IL (1) IL140771A (pt)
MX (1) MX217361B (pt)
PL (1) PL199235B1 (pt)
SK (1) SK287838B6 (pt)
TR (1) TR200100196T2 (pt)
WO (1) WO2000005307A1 (pt)

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DE10260920A1 (de) * 2002-12-20 2004-07-01 Röhm GmbH & Co. KG Verfahren zur Herstellung von Arnzeiformen oder Nahrungsergänzungsmitteln mit pigmentierten Polymerüberzügen
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US20050136114A1 (en) * 2003-12-19 2005-06-23 Council Of Scientific And Industrial Research Taste masked pharmaceutical compositions comprising bitter drug and pH sensitive polymer
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) * 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US20060127479A1 (en) * 2004-10-08 2006-06-15 Natrajan Kumaraperumal Solvent free taste masked pharmaceutical compositions
AU2004325469B2 (en) * 2004-12-10 2009-02-05 Council Of Scientific And Industrial Research Pharmaceutical composition for improving palatability of drugs and process for preparation thereof
US8874082B2 (en) * 2005-05-25 2014-10-28 Qualcomm Incorporated Apparatus and methods for protecting data on a wireless device
DE102005042039A1 (de) * 2005-09-02 2007-03-08 Basf Ag Wässrige Polyvinylacetatdispersionen mit hoher Scherstabilität
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
WO2007112581A1 (en) 2006-04-03 2007-10-11 Isa Odidi Controlled release delivery device comprising an organosol coat
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
US8790693B2 (en) 2007-08-02 2014-07-29 Basf Se Aqueous polymer dispersion based on N,N-diethylaminoethyl methacrylate, its preparation and use
US8038721B2 (en) * 2007-12-17 2011-10-18 Anna Love Soft tissue filler
JP5619131B2 (ja) * 2009-03-18 2014-11-05 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツングＥｖｏｎｉｋ ＲｏｅｈｍＧｍｂＨ ポリマー混合物と賦形剤とを含むコーティングを使用するエタノールの影響に対する耐性を有する制御放出性医薬組成物
WO2011051155A2 (en) 2009-10-28 2011-05-05 Basf Se Stable protective coatings for pharmaceutical dosage forms
EP2613770A1 (de) 2010-09-07 2013-07-17 Basf Se Verwendung von copolymeren auf basis von aminogruppenhaltigen polymeren als matrixbindemittel für die herstellung von wirkstoffhaltigen granulaten und darreichungsformen
CN103221038B (zh) 2010-09-27 2019-05-07 巴斯夫欧洲公司 酸性活性成分的保护涂层
US9795576B2 (en) 2010-09-27 2017-10-24 Basf Se Protective coatings for acidic active ingredients
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CN103347931B (zh) 2011-02-28 2016-02-17 巴斯夫欧洲公司 制备用于药物剂型的稳定保护性衣层的粉末包衣剂
WO2012116941A1 (de) 2011-02-28 2012-09-07 Basf Se Herstellung von pulverförmigen überzugsmitteln für stabile protektive überzüge für pharmazeutische dosierungsformen
US8865250B2 (en) 2011-02-28 2014-10-21 Basf Se Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms
US8962064B2 (en) 2011-02-28 2015-02-24 Basf Se Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms
US9044734B2 (en) 2011-09-23 2015-06-02 Basf Se Diesel oxidation catalyst with layered structure containing ceria composition as palladium support material for enhanced HC and CO gas conversion
US20130236505A1 (en) 2012-03-09 2013-09-12 Basf Se Production Of Pharmaceutical Protective Coatings With Good Resistance In A Neutral Environment
EP2636403A1 (de) 2012-03-09 2013-09-11 Basf Se Herstellung von pharmazeutischen protektiven Überzügen mit guter Resistenz im neutralen Milieu
US10668156B2 (en) 2012-06-22 2020-06-02 Basf Se Active-ingredient-containing solid dispersions based on diethylaminoethyl methacrylate copolymers
EP2863953A1 (de) 2012-06-22 2015-04-29 Basf Se Wirkstoffhaltige festen dispersionen auf basis von diethylaminoethylmethacrylat-copolymeren
CA2886626A1 (en) 2012-09-28 2014-04-03 Evonik Industries Ag Process for preparing aqueous dispersions
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Also Published As

Publication number Publication date
DE59903917D1 (de) 2003-02-06
CA2338750A1 (en) 2000-02-03
US6846891B2 (en) 2005-01-25
SK287838B6 (sk) 2011-12-05
BR9912353B1 (pt) 2012-01-24
JP2002521393A (ja) 2002-07-16
TR200100196T2 (tr) 2001-06-21
KR20060092288A (ko) 2006-08-22
JP4636687B2 (ja) 2011-02-23
EP1098935A1 (de) 2001-05-16
SK792001A3 (en) 2002-01-07
DE19918435A1 (de) 2000-01-27
CA2338750C (en) 2009-12-08
KR20010079560A (ko) 2001-08-22
HK1041014B (zh) 2004-10-08
CN1307613A (zh) 2001-08-08
MXPA01000793A (es) 2002-04-08
PL345581A1 (en) 2001-12-17
IL140771A0 (en) 2002-02-10
MX217361B (es) 2003-11-04
PL199235B1 (pl) 2008-08-29
HK1041014A1 (en) 2002-06-28
US20030220413A1 (en) 2003-11-27
IL140771A (en) 2005-06-19
ATE230426T1 (de) 2003-01-15
US6624210B1 (en) 2003-09-23
KR100646114B1 (ko) 2006-11-17
KR100663663B1 (ko) 2007-01-03
WO2000005307A1 (de) 2000-02-03
AU4781599A (en) 2000-02-14
CN1142212C (zh) 2004-03-17
ES2190226T3 (es) 2003-07-16
EP1098935B1 (de) 2003-01-02

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B25D Requested change of name of applicant approved

Owner name: EVONIK ROEHM GMBH (DE)

Free format text: NOME ALTERADO DE: ROEHM GMBH

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 24/01/2012, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 20A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2521 DE 30-04-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.