BR9911890A - Preparado contendo produto medicinal de elevado peso molecular na forma em pó para administração através da mucosa - Google Patents

Preparado contendo produto medicinal de elevado peso molecular na forma em pó para administração através da mucosa

Info

Publication number
BR9911890A
BR9911890A BR9911890-4A BR9911890A BR9911890A BR 9911890 A BR9911890 A BR 9911890A BR 9911890 A BR9911890 A BR 9911890A BR 9911890 A BR9911890 A BR 9911890A
Authority
BR
Brazil
Prior art keywords
molecular weight
high molecular
mucosa
medicinal product
powder form
Prior art date
Application number
BR9911890-4A
Other languages
English (en)
Inventor
Hedeaki Nomura
Yosuke Ueki
Original Assignee
Kirin Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26422571&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9911890(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kirin Amgen Inc filed Critical Kirin Amgen Inc
Publication of BR9911890A publication Critical patent/BR9911890A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Otolaryngology (AREA)
  • Toxicology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: <B>"PREPARADO CONTENDO PRODUTO MEDICINAL DE ELEVADO PESO MOLECULAR NA FORMA EM Pó PARA ADMINISTRAçãO ATRAVéS DA MUCOSA"<D>. é divulgado um preparado na forma em pó para administração através da mucosa, compreendendo um produto medicinal de elevado peso molecular e um polímero catiónico. Através da adição de um polímero catiónico (em particular, um copolímero de aminoalquilmetacrilato ou acetal dietilaminoacetato de polivinila) ou um polímero catiónico mais um polímero viscoso a um produto medicinal de elevado peso molecular para a produção de um preparado na forma em pó, é possível obter uma absorção efetiva do produto medicinal de elevado peso molecular através da mucosa.
BR9911890-4A 1998-07-08 1999-07-01 Preparado contendo produto medicinal de elevado peso molecular na forma em pó para administração através da mucosa BR9911890A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP19272298 1998-07-08
JP8154999 1999-03-25
PCT/JP1999/003563 WO2000002574A1 (fr) 1998-07-08 1999-07-01 Preparation en poudre pour administration par les muqueuses

Publications (1)

Publication Number Publication Date
BR9911890A true BR9911890A (pt) 2001-03-27

Family

ID=26422571

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9911890-4A BR9911890A (pt) 1998-07-08 1999-07-01 Preparado contendo produto medicinal de elevado peso molecular na forma em pó para administração através da mucosa

Country Status (27)

Country Link
US (2) US20050271728A1 (pt)
EP (2) EP1637154A3 (pt)
JP (1) JP3422775B2 (pt)
KR (1) KR100606857B1 (pt)
CN (1) CN1180839C (pt)
AT (1) ATE320816T1 (pt)
AU (1) AU764331B2 (pt)
BG (1) BG65040B1 (pt)
BR (1) BR9911890A (pt)
CA (1) CA2332559C (pt)
CZ (1) CZ300931B6 (pt)
DE (1) DE69930509T2 (pt)
DK (1) DK1093818T3 (pt)
EA (1) EA003672B1 (pt)
ES (1) ES2260916T3 (pt)
HK (1) HK1039283B (pt)
HU (1) HUP0103396A3 (pt)
IL (2) IL140669A0 (pt)
MX (1) MXPA01000032A (pt)
NO (1) NO20010042L (pt)
NZ (1) NZ509710A (pt)
PL (1) PL193805B1 (pt)
PT (1) PT1093818E (pt)
RS (1) RS49890B (pt)
SK (1) SK262001A3 (pt)
TW (1) TWI225411B (pt)
WO (1) WO2000002574A1 (pt)

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CU23317A1 (es) * 2005-07-22 2008-10-22 Ct De Investigacia N Y Desarro Formulaciones nasales de eporh con bajo contenido de ã cido siã lico para el tratamiento de enfermedades del sistema nervioso central
US8268307B2 (en) * 2007-03-19 2012-09-18 University Of Florida Research Foundation, Inc. Enhancing efficacy of vaccines administered via the respiratory tract
JP5171102B2 (ja) * 2007-05-02 2013-03-27 東亜薬品株式会社 経鼻吸収用睡眠導入剤
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US11524058B2 (en) 2008-09-29 2022-12-13 The Corporation Of Mercer University Oral dissolving films containing microencapsulated vaccines and methods of making same
US10004790B2 (en) 2008-09-29 2018-06-26 The Corporation Of Mercer University Nanospheres encapsulating bioactive material and method for formulation of nanospheres
US10463608B2 (en) 2008-09-29 2019-11-05 The Corporation Of Mercer University Microneedle-based transdermal delivery system and method of making same
JP5804453B2 (ja) * 2009-05-14 2015-11-04 国立大学法人 東京大学 結晶性ポリオール微粒子及びその調製方法
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DK2833914T3 (en) * 2012-04-04 2019-03-11 Vaxform Llc ADMINISTRATIVE SYSTEM FOR ORAL VACCINE ADMINISTRATION
CN104208029B (zh) * 2013-05-30 2017-06-06 上海医药工业研究院 一种鼻用疫苗组合物粉体制剂及其制备方法
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WO2017062463A1 (en) 2015-10-05 2017-04-13 The Corporation Of Mercer University Nanospheres encapsulating bioactive material and method for formulation of nanospheres
EP3459529A1 (en) * 2017-09-20 2019-03-27 Tillotts Pharma Ag Preparation of sustained release solid dosage forms comprising antibodies by spray drying
JP2021528498A (ja) * 2018-06-22 2021-10-21 ビオラリクス ベー．フェー． 経口投与用生物学的ポリマーの製剤
JP2023526098A (ja) 2020-05-18 2023-06-20 オレクソ・アクチエボラゲット 薬物送達のための新しい医薬組成物
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Also Published As

Publication number Publication date
WO2000002574A1 (fr) 2000-01-20
HK1039283A1 (en) 2002-04-19
NZ509710A (en) 2003-10-31
EP1093818B9 (en) 2007-10-17
BG105169A (en) 2001-12-29
CA2332559C (en) 2008-01-15
ES2260916T3 (es) 2006-11-01
DE69930509T2 (de) 2006-11-30
DK1093818T3 (da) 2006-07-17
US20050271728A1 (en) 2005-12-08
JP3422775B2 (ja) 2003-06-30
EP1637154A2 (en) 2006-03-22
EP1637154A3 (en) 2007-08-15
HUP0103396A3 (en) 2002-05-28
SK262001A3 (en) 2001-09-11
CZ20016A3 (en) 2001-05-16
PL193805B1 (pl) 2007-03-30
CZ300931B6 (cs) 2009-09-16
BG65040B1 (bg) 2007-01-31
CN1180839C (zh) 2004-12-22
PL345456A1 (en) 2001-12-17
YU1101A (sh) 2003-08-29
HUP0103396A2 (hu) 2002-02-28
EP1093818B1 (en) 2006-03-22
EP1093818A1 (en) 2001-04-25
EA200100118A1 (ru) 2001-08-27
ATE320816T1 (de) 2006-04-15
KR100606857B1 (ko) 2006-08-01
RS49890B (sr) 2008-08-07
PT1093818E (pt) 2006-07-31
KR20010053302A (ko) 2001-06-25
US20090028814A1 (en) 2009-01-29
IL140669A0 (en) 2002-02-10
IL140669A (en) 2007-06-03
TWI225411B (en) 2004-12-21
CN1315864A (zh) 2001-10-03
EP1093818A4 (en) 2004-03-31
MXPA01000032A (es) 2002-10-17
EA003672B1 (ru) 2003-08-28
HK1039283B (zh) 2005-04-29
AU764331B2 (en) 2003-08-14
NO20010042D0 (no) 2001-01-04
CA2332559A1 (en) 2000-01-20
NO20010042L (no) 2001-03-05
DE69930509D1 (de) 2006-05-11
AU4395899A (en) 2000-02-01

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