ATE270544T1 - Halbfeste arzneizubereitung enthaltend isotretinoin - Google Patents
Halbfeste arzneizubereitung enthaltend isotretinoinInfo
- Publication number
- ATE270544T1 ATE270544T1 AT01969090T AT01969090T ATE270544T1 AT E270544 T1 ATE270544 T1 AT E270544T1 AT 01969090 T AT01969090 T AT 01969090T AT 01969090 T AT01969090 T AT 01969090T AT E270544 T1 ATE270544 T1 AT E270544T1
- Authority
- AT
- Austria
- Prior art keywords
- semi
- preparation containing
- medicinal preparation
- solid medicinal
- isotretinoin
- Prior art date
Links
- SHGAZHPCJJPHSC-NUEINMDLSA-N Isotretinoin Chemical compound OC(=O)C=C(C)/C=C/C=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-NUEINMDLSA-N 0.000 title abstract 2
- 229960005280 isotretinoin Drugs 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title 1
- 239000008203 oral pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE0000111 | 2000-09-22 | ||
| PCT/BE2001/000163 WO2002024172A1 (en) | 2000-09-22 | 2001-09-21 | Pharmaceutical semi-solid composition of isotretinoin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE270544T1 true ATE270544T1 (de) | 2004-07-15 |
Family
ID=3862550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01969090T ATE270544T1 (de) | 2000-09-22 | 2001-09-21 | Halbfeste arzneizubereitung enthaltend isotretinoin |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US7435427B2 (de) |
| EP (1) | EP1318791B1 (de) |
| AT (1) | ATE270544T1 (de) |
| AU (1) | AU2001289438A1 (de) |
| BR (1) | BR102013032172A2 (de) |
| CA (1) | CA2423170A1 (de) |
| DE (1) | DE60104206T2 (de) |
| ES (1) | ES2225600T3 (de) |
| PT (1) | PT1318791E (de) |
| WO (1) | WO2002024172A1 (de) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2376400A1 (en) | 1999-06-08 | 2000-12-14 | University Of Iowa Research Foundation | Compounds and methods to enhance raav transduction |
| US7435427B2 (en) | 2000-09-22 | 2008-10-14 | Galephar M/F | Pharmaceutical semi-solid composition of isotretinoin |
| ITMI20011338A1 (it) * | 2001-06-26 | 2002-12-26 | Farmatron Ltd | Composizioni farmaceutiche orali a rilascio immediato del principio attivo |
| FI20030426L (fi) * | 2003-03-24 | 2004-09-25 | Tomi Jaervinen | Syklodekstriinikompleksit |
| CA2520016A1 (en) | 2003-03-31 | 2004-10-21 | University Of Iowa Research Foundation | Pharmico-gene therapy of epithelial sodium channel associated disorders |
| SE0303135D0 (sv) * | 2003-11-25 | 2003-11-25 | Lipocore Holding Ab | Controlled food effect composition |
| WO2006102157A1 (en) * | 2005-03-21 | 2006-09-28 | Ivax Pharmaceuticals S.R.O. | Crystallization inhibitor and its use in gelatin capsules |
| AU2008215659B2 (en) * | 2007-02-16 | 2012-11-01 | Aska Pharmaceutical Co., Ltd. | Pharmaceutical composition comprising microparticle oily suspension |
| RU2392933C2 (ru) * | 2008-07-18 | 2010-06-27 | Учреждение Российской Академии Медицинских Наук Научно-исследовательский институт экспериментальной медицины Северо-западного отделения РАМН (НИИЭМ СЗО РАМН) | Средство, обладающее гиполипидемическими свойствами |
| WO2010109259A1 (es) * | 2009-03-26 | 2010-09-30 | Grufarcol Ltda | Métoda para preparar formulaciones de gel blando de isotretinoína líquida y la formulaciones obtenidas |
| SG176097A1 (en) | 2009-05-20 | 2011-12-29 | Ranbaxy Lab Ltd | Topical retinoid solutions |
| US10022348B2 (en) | 2009-05-20 | 2018-07-17 | Sun Pharmaceutical Industries Limited | Topical solution of isotretinoin |
| CA2762391C (en) | 2009-05-20 | 2017-02-07 | Ranbaxy Laboratories Limited | Liquid dosage forms of isotretinoin |
| US9078925B2 (en) | 2012-06-18 | 2015-07-14 | Galephar Pharmaceutical Research, Inc. | Pharmaceutical semi-solid composition of isotretinoin |
| AU2014212004B2 (en) * | 2013-02-04 | 2018-09-20 | Société des Produits Nestlé S.A. | Compositions for treating or preventing or reducing the severity of clostridium difficile related diseases |
| JP2016535106A (ja) | 2013-09-25 | 2016-11-10 | スリーエム イノベイティブ プロパティズ カンパニー | 電界グレーディング用組成物 |
| JP6704345B2 (ja) * | 2014-01-17 | 2020-06-03 | オンコラル ファーマ エーピーエス | 癌治療のためのイリノテカンの固体経口剤形 |
| EP3148644A4 (de) | 2014-05-29 | 2017-12-20 | Sun Pharmaceutical Industries Ltd | Orale pharmazeutische zusammensetzung aus isotretinoin |
| RU2016150868A (ru) * | 2014-06-02 | 2018-07-17 | Сан Фармасьютикал Индастриз Лимитед | Пероральная фармацевтическая композиция изотретиноина |
| MA40447A (fr) | 2014-07-31 | 2016-02-04 | Sun Pharmaceutical Ind Ltd | Composition pharmaceutique orale d'isotrétinoïne |
| US9750711B2 (en) | 2014-10-01 | 2017-09-05 | Sun Pharmaceutical Industries Limited | Low dose oral pharmaceutical composition of isotretinoin |
| MA40781A (fr) * | 2014-10-01 | 2017-08-08 | Sun Pharmaceutical Ind Ltd | Composition pharmaceutique d'isotrétinoïne à faible dosage destinée à la voie orale |
| WO2016189481A1 (en) * | 2015-05-25 | 2016-12-01 | Sun Pharmaceutical Industries Limited | Once daily oral pharmaceutical composition of isotretinoin |
| CA2987517A1 (en) * | 2015-05-29 | 2016-12-08 | Sun Pharmaceutical Industries Limited | Oral pharmaceutical composition of isotretinoin |
| WO2017139381A1 (en) | 2016-02-08 | 2017-08-17 | University Of Iowa Research Foundation | Methods to produce chimeric adeno-associated virus/bocavirus parvovirus |
| IL322737A (en) | 2016-03-07 | 2025-10-01 | Univ Iowa Res Found | AAV-mediated expression using a synthetic promoter and enhancer |
| US10285987B2 (en) | 2017-04-28 | 2019-05-14 | Amplipharm Pharmaceuticals, LLC | Device and kit for dosing and dispensing non-liquid medicine |
| CA3062764A1 (en) | 2016-04-28 | 2017-11-02 | Amplipharm Pharmaceuticals, LLC | Temozolomide powder formulation |
| US9949967B2 (en) | 2016-04-28 | 2018-04-24 | Amplipharm Pharmaceuticals, LLC | Temozolomide powder formulation |
| WO2017203365A1 (en) | 2016-05-26 | 2017-11-30 | Dr. Reddy's Laboratiories Ltd. | Pharmaceutical compositions for treating acne |
| WO2017205739A1 (en) | 2016-05-26 | 2017-11-30 | University Of Iowa Research Foundation | cis AND trans REQUIREMENTS FOR TERMINAL RESOLUTION OF HUMAN BOCAVIRUS 1 |
| WO2018132747A1 (en) | 2017-01-13 | 2018-07-19 | University Of Iowa Research Foundation | Bocaparvovirus small noncoding rna and uses thereof |
| WO2018200034A1 (en) * | 2017-04-28 | 2018-11-01 | Amplipharm Pharmaceuticals, LLC | Device and kit for dosing and dispensing non-liquid medicine |
| CN111032017A (zh) | 2017-06-29 | 2020-04-17 | 地平线生物科学有限责任公司 | 异维a酸口腔粘膜制剂及其使用方法 |
| US10716774B1 (en) | 2018-01-05 | 2020-07-21 | Yale Pharmaceuticals LLC | Pharmaceutical compositions containing isotretinoin with improved dissolution profile and enhanced stability |
| EP4236915A4 (de) * | 2020-11-01 | 2024-10-23 | Idrs Labs Pvt Ltd | Orale flüssige pharmazeutische zusammensetzungen von isotretinoin |
| MA69876A1 (fr) | 2022-07-01 | 2025-11-28 | Acrotech Biopharma Inc. | Compositions pharmaceutiques comprenant de l'isotrétinoïne ainsi que leurs procédés de préparation et leurs utilisations |
| WO2024236523A1 (en) | 2023-05-16 | 2024-11-21 | Sun Pharmaceutical Industries Limited | Once daily isotretinoin composition |
| CN116869940A (zh) * | 2023-07-26 | 2023-10-13 | 中国科学院上海药物研究所 | 异维a酸的共晶固体分散体及其制备方法和应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA713539B (en) * | 1970-06-23 | 1972-02-23 | Hoffmann La Roche | Pharmaceutical compositions |
| US4530213A (en) | 1983-06-28 | 1985-07-23 | Air Products And Chemicals, Inc. | Economical and thermally efficient cryopump panel and panel array |
| US4678663A (en) * | 1984-02-06 | 1987-07-07 | Nuetrogena Corporation | Hydroquinone composition having enhanced bio-availability and percutaneous adsorption |
| CA1282326C (en) | 1984-12-14 | 1991-04-02 | Paul J. Jarosz | Pharmaceutical composition containing 13-cis vitamin a acid as the active ingredient |
| US5252604A (en) * | 1992-07-10 | 1993-10-12 | Hoffmann-La Roche Inc. | Compositions of retinoic acids and tocopherol for prevention of dermatitis |
| US6054136A (en) | 1993-09-30 | 2000-04-25 | Gattefosse S.A. | Orally administrable composition capable of providing enhanced bioavailability when ingested |
| US5993858A (en) * | 1996-06-14 | 1999-11-30 | Port Systems L.L.C. | Method and formulation for increasing the bioavailability of poorly water-soluble drugs |
| US5993585A (en) * | 1998-01-09 | 1999-11-30 | Nike, Inc. | Resilient bladder for use in footwear and method of making the bladder |
| US6020003A (en) * | 1998-02-23 | 2000-02-01 | Basf Corporation | Method of making spray-dried powders with high edible-oil loadings based on non-hydrolyzed gelatin |
| FR2775597B1 (fr) | 1998-03-04 | 2001-04-20 | Gattefosse Ets Sa | Pellet administrable par voie orale apte a ameliorer la biodisponibilite de la substance active, procede de fabrication |
| KR100336090B1 (ko) * | 1998-06-27 | 2002-05-27 | 윤승원 | 오일, 지방산 또는 이들의 혼합물을 함유한 난용성 약물의 고형분산제제 |
| PE20001227A1 (es) * | 1998-10-30 | 2000-11-06 | Hoffmann La Roche | Procesos para producir una composicion de isotretinoina |
| WO2000025572A1 (en) | 1998-11-04 | 2000-05-11 | Jagjit Singh Kaurah | Improved automatic plant watering system and water level control |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US6267985B1 (en) * | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| US6383471B1 (en) * | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
| US6624154B1 (en) * | 1999-04-23 | 2003-09-23 | Bristol-Myers Squibb Company | Compositions and methods for treatment of hyperproliferative diseases |
| EP2269654A3 (de) * | 1999-08-24 | 2011-04-13 | Cellgate Inc. | Verbesserung des Verabreichung von Arzneimitteln durch und in epitheliale Gewebe rch Verwendung von Oligoarginin-Gruppen |
| US6267798B1 (en) * | 2000-02-02 | 2001-07-31 | Nuflux, Llc | Composition for treating steel making slags |
| IN192188B (de) * | 2000-06-16 | 2004-03-13 | Ranbaxy Lab Ltd | |
| US7435427B2 (en) | 2000-09-22 | 2008-10-14 | Galephar M/F | Pharmaceutical semi-solid composition of isotretinoin |
| CA2762391C (en) | 2009-05-20 | 2017-02-07 | Ranbaxy Laboratories Limited | Liquid dosage forms of isotretinoin |
| RU2400226C1 (ru) | 2009-06-08 | 2010-09-27 | Юрий Степанович Макляков | Способ лечения угревой болезни |
-
2001
- 2001-09-21 US US10/380,619 patent/US7435427B2/en not_active Expired - Lifetime
- 2001-09-21 WO PCT/BE2001/000163 patent/WO2002024172A1/en not_active Ceased
- 2001-09-21 CA CA002423170A patent/CA2423170A1/en not_active Abandoned
- 2001-09-21 DE DE60104206T patent/DE60104206T2/de not_active Expired - Fee Related
- 2001-09-21 ES ES01969090T patent/ES2225600T3/es not_active Expired - Lifetime
- 2001-09-21 PT PT01969090T patent/PT1318791E/pt unknown
- 2001-09-21 AT AT01969090T patent/ATE270544T1/de not_active IP Right Cessation
- 2001-09-21 EP EP01969090A patent/EP1318791B1/de not_active Expired - Lifetime
- 2001-09-21 AU AU2001289438A patent/AU2001289438A1/en not_active Abandoned
-
2007
- 2007-08-22 US US11/892,363 patent/US8367102B2/en not_active Expired - Lifetime
-
2012
- 2012-06-18 US US13/525,904 patent/US20130096196A1/en not_active Abandoned
- 2012-06-18 US US13/525,857 patent/US8952064B2/en not_active Expired - Lifetime
- 2012-12-13 US US13/713,897 patent/US9089534B2/en not_active Expired - Lifetime
-
2013
- 2013-12-13 BR BR102013032172-9A patent/BR102013032172A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2225600T3 (es) | 2005-03-16 |
| US20080171084A1 (en) | 2008-07-17 |
| US20040009225A1 (en) | 2004-01-15 |
| DE60104206T2 (de) | 2005-09-22 |
| US8367102B2 (en) | 2013-02-05 |
| US20130217769A1 (en) | 2013-08-22 |
| US8952064B2 (en) | 2015-02-10 |
| US20130096196A1 (en) | 2013-04-18 |
| EP1318791A1 (de) | 2003-06-18 |
| AU2001289438A1 (en) | 2002-04-02 |
| DE60104206D1 (de) | 2004-08-12 |
| US20130158119A1 (en) | 2013-06-20 |
| US7435427B2 (en) | 2008-10-14 |
| BR102013032172A2 (pt) | 2017-10-24 |
| EP1318791B1 (de) | 2004-07-07 |
| CA2423170A1 (en) | 2002-03-28 |
| US9089534B2 (en) | 2015-07-28 |
| PT1318791E (pt) | 2004-11-30 |
| WO2002024172A1 (en) | 2002-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |