ATE530197T1 - Medizinische zusammensetzungen zur angiogenese- therapie - Google Patents

Medizinische zusammensetzungen zur angiogenese- therapie

Info

Publication number
ATE530197T1
ATE530197T1 AT07021738T AT07021738T ATE530197T1 AT E530197 T1 ATE530197 T1 AT E530197T1 AT 07021738 T AT07021738 T AT 07021738T AT 07021738 T AT07021738 T AT 07021738T AT E530197 T1 ATE530197 T1 AT E530197T1
Authority
AT
Austria
Prior art keywords
angiogenic
gene
effect
contain
active ingredient
Prior art date
Application number
AT07021738T
Other languages
English (en)
Inventor
Ryuichi Morishita
Hiromi Koike
Tadashi Tanabe
Motokuni Aoki
Original Assignee
Anges Mg Inc
Ryuichi Morishita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anges Mg Inc, Ryuichi Morishita filed Critical Anges Mg Inc
Application granted granted Critical
Publication of ATE530197T1 publication Critical patent/ATE530197T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/52Isomerases (5)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1833Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT07021738T 2000-06-27 2001-06-27 Medizinische zusammensetzungen zur angiogenese- therapie ATE530197T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000192480 2000-06-27
JP2000388624 2000-12-21

Publications (1)

Publication Number Publication Date
ATE530197T1 true ATE530197T1 (de) 2011-11-15

Family

ID=26594742

Family Applications (2)

Application Number Title Priority Date Filing Date
AT07021738T ATE530197T1 (de) 2000-06-27 2001-06-27 Medizinische zusammensetzungen zur angiogenese- therapie
AT01943840T ATE395071T1 (de) 2000-06-27 2001-06-27 Pharmazeutische zubereitungen zur angiogenese- therapie

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT01943840T ATE395071T1 (de) 2000-06-27 2001-06-27 Pharmazeutische zubereitungen zur angiogenese- therapie

Country Status (10)

Country Link
US (2) US20030171287A1 (de)
EP (2) EP1889633B1 (de)
KR (1) KR100798566B1 (de)
CN (1) CN1274365C (de)
AT (2) ATE530197T1 (de)
AU (2) AU6633801A (de)
CA (1) CA2413768A1 (de)
DE (1) DE60134021D1 (de)
NZ (1) NZ523613A (de)
WO (1) WO2002000258A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE409494T1 (de) * 1999-10-29 2008-10-15 Anges Mg Inc Gentherapie für diabetische ischämie
JPWO2002064165A1 (ja) * 2001-02-13 2004-06-10 久光製薬株式会社 Ets転写因子又はそれをコードする遺伝子からなる細胞増殖抑制剤
KR100562824B1 (ko) * 2002-03-20 2006-03-23 주식회사 바이로메드 유전자 발현효율이 높으며 간세포 성장인자의 두 가지이형체를 동시에 발현하는 하이브리드 간세포 성장인자유전자
US7259149B2 (en) * 2002-12-02 2007-08-21 Anges Mg, Inc. Methods for treating or preventing angiogenesis-dependent symptoms
JPWO2005021045A1 (ja) * 2003-08-29 2006-10-26 アンジェスMg株式会社 針無注射器を用いた皮膚疾患の遺伝子治療
WO2005084700A1 (en) * 2004-03-09 2005-09-15 Tohoku Technoarch Co., Ltd. An agent for promoting induction of vascular differentiation, comprising hepatocyte growth factor
US8226977B2 (en) 2004-06-04 2012-07-24 Teva Pharmaceutical Industries Ltd. Pharmaceutical composition containing irbesartan
US7608416B2 (en) * 2004-12-07 2009-10-27 The Trustees Of The University Of Pennsylvania Targeting mPGES-1 as a treatment for inflammation which avoids cardiovascular risk
US7252834B2 (en) 2005-04-25 2007-08-07 Clemson University Research Foundation (Curf) Elastin stabilization of connective tissue
US20090202606A1 (en) * 2008-01-25 2009-08-13 Viromed Co., Ltd. Treatment and Prevention of Cardiac Conditions Using Two or More Isoforms of Hepatocyte Growth Factor
US20090214654A1 (en) * 2008-02-21 2009-08-27 Isenburg Jason C Treatment of aneurysm with application of connective tissue stabilization agent in combination with a delivery vehicle
EP2281040B1 (de) * 2008-04-09 2015-11-25 Viromed Co., Ltd. Lyophilisierte dna-formulierungen zur verbesserten expression von plasmid-dna
JP5725489B2 (ja) 2008-06-27 2015-05-27 公立大学法人大阪市立大学 医療用組成物および医療用キット
US20100016833A1 (en) * 2008-07-15 2010-01-21 Ogle Matthew F Devices for the Treatment of Vascular Aneurysm
US20100119605A1 (en) * 2008-11-12 2010-05-13 Isenburg Jason C Compositions for tissue stabilization
US8496911B2 (en) 2009-07-29 2013-07-30 Vatrix CHF, Inc. Tissue stabilization for heart failure
JP5779750B2 (ja) * 2009-08-31 2015-09-16 恵一 福田 血管新生療法用医薬組成物
EP2485687A1 (de) * 2009-10-09 2012-08-15 Vatrix Medical, Inc. Chemische in-vivo-stabilisierung empfindlicher plaque
US8444624B2 (en) 2009-10-19 2013-05-21 Vatrix Medical, Inc. Vascular medical devices with sealing elements and procedures for the treatment of isolated vessel sections
US8911468B2 (en) 2011-01-31 2014-12-16 Vatrix Medical, Inc. Devices, therapeutic compositions and corresponding percutaneous treatment methods for aortic dissection
EP2709711B8 (de) 2011-05-18 2017-03-22 Vatrix Medical, Inc. Beschichtete ballons zur blutgefässstabilisierung
US9283241B2 (en) 2012-07-10 2016-03-15 Clemson University Treatment to render implants resistant to diabetes
JP6240337B2 (ja) 2013-10-22 2017-11-29 バイロメッド カンパニー リミテッド 肝細胞増殖因子の2つ以上のアイソフォームを利用した筋萎縮性側索硬化症の予防又は治療用組成物
KR102015197B1 (ko) 2014-06-12 2019-08-27 티엑스 메딕 에이비 대상체에서의 혈관신생을 유도하기 위한 10000Da 미만의 평균 분자량을 가지는 황산덱스트란의 용도
BR112021000722A2 (pt) 2018-07-19 2021-05-04 Helixmith Co., Ltd. composições farmacêuticas liofilizadas para terapia gênica de dna nu
GB201814281D0 (en) 2018-09-03 2018-10-17 Femtogenix Ltd Cytotoxic agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995030013A1 (en) 1994-04-28 1995-11-09 Tadashi Tanabe Human-origin prostacyclin synthase
US5830879A (en) * 1995-10-02 1998-11-03 St. Elizabeth's Medical Center Of Boston, Inc. Treatment of vascular injury using vascular endothelial growth factor
US6121246A (en) * 1995-10-20 2000-09-19 St. Elizabeth's Medical Center Of Boston, Inc. Method for treating ischemic tissue
JP3058828B2 (ja) * 1996-03-15 2000-07-04 株式会社巴川製紙所 電子写真トナー用ポリエステル系樹脂、該樹脂の製造方法及び該樹脂を用いた電子写真用トナー
US5785965A (en) * 1996-05-15 1998-07-28 The Board Of Trustees Of The Leland Stanford Junior Univ. VEGF gene transfer into endothelial cells for vascular prosthesis
US20030219380A1 (en) * 1997-11-07 2003-11-27 Annie Fong Method of determining an efficacious dose of a drug
AUPP459998A0 (en) * 1998-07-09 1998-07-30 Monash University Modulation of haemopoietic cell activity and inflammation via the ets-1 gene and agents useful for same
DE19940012A1 (de) 1999-08-24 2001-03-08 Karin Faerber Neues Mittel aus mindestens zwei Komponenten, das zum einen Gefäßneubildung (Neoangiogense) induziert des weiteren jedoch auch Gefäßverschlüsse (Restenosen) verhindert, das Verfahren seiner Herstellung und seine Verwendung
JP2001199903A (ja) * 1999-11-09 2001-07-24 Eizo Mori 核酸含有複合体
DE60128540T2 (de) * 2000-02-09 2008-01-31 Bas Medical, Inc., San Mateo Verwendung von relaxin zur behandlung von durch gefässverengung bedingten erkrankungen
US6533541B1 (en) 2001-12-04 2003-03-18 Honeywell International, Inc. High energy particle arrestor for air turbine starters

Also Published As

Publication number Publication date
AU2001266338B2 (en) 2006-11-09
CN1274365C (zh) 2006-09-13
EP1300158B1 (de) 2008-05-14
EP1300158A4 (de) 2005-04-13
ATE395071T1 (de) 2008-05-15
CN1446105A (zh) 2003-10-01
EP1300158A1 (de) 2003-04-09
WO2002000258A8 (en) 2003-01-23
WO2002000258A1 (en) 2002-01-03
CA2413768A1 (en) 2002-01-03
EP1889633A1 (de) 2008-02-20
EP1889633B1 (de) 2011-10-26
US20100240735A1 (en) 2010-09-23
NZ523613A (en) 2005-02-25
US20030171287A1 (en) 2003-09-11
US7994151B2 (en) 2011-08-09
DE60134021D1 (de) 2008-06-26
EP1300158B9 (de) 2008-11-19
AU2001266338B8 (en) 2006-12-14
AU6633801A (en) 2002-01-08
KR20030014391A (ko) 2003-02-17
KR100798566B1 (ko) 2008-01-28

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