BR9910643A - Processos e produtos para a indução de imunidadede mucosa - Google Patents

Processos e produtos para a indução de imunidadede mucosa

Info

Publication number
BR9910643A
BR9910643A BR9910643-4A BR9910643A BR9910643A BR 9910643 A BR9910643 A BR 9910643A BR 9910643 A BR9910643 A BR 9910643A BR 9910643 A BR9910643 A BR 9910643A
Authority
BR
Brazil
Prior art keywords
products
mucosal immunity
processes
inducing mucosal
inducing
Prior art date
Application number
BR9910643-4A
Other languages
English (en)
Inventor
Michael J Mccluskie
Heather L Davis
Original Assignee
Loeb Health Res Inst At The Ot
Oley Pharmaceutical Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22198286&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9910643(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Loeb Health Res Inst At The Ot, Oley Pharmaceutical Group Inc filed Critical Loeb Health Res Inst At The Ot
Publication of BR9910643A publication Critical patent/BR9910643A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/5555—Muramyl dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS

Abstract

"PROCESSOS E PRODUTOS PARA A INDUçãO DEIMUNIDADE DE MUCOSA". A invenção se refere a processos e aprodutos para a indução de imunidade de mucosa. Em particular, ainvenção se refere ao uso de oligonucleotídeosimunoestimuladores contendo um motivo CpG para induzir aimunidade da mucosa. Os oligonucleotídeos imunoestimuladoresCpG podem ser administrados isoladamente ou em combinaçãocom um antígeno e/ou com outros adjuvantes.
BR9910643-4A 1998-05-22 1999-05-21 Processos e produtos para a indução de imunidadede mucosa BR9910643A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8639398P 1998-05-22 1998-05-22
PCT/US1999/011359 WO1999061056A2 (en) 1998-05-22 1999-05-21 Methods and products for inducing mucosal immunity

Publications (1)

Publication Number Publication Date
BR9910643A true BR9910643A (pt) 2001-10-30

Family

ID=22198286

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9910643-4A BR9910643A (pt) 1998-05-22 1999-05-21 Processos e produtos para a indução de imunidadede mucosa

Country Status (18)

Country Link
US (2) US8574599B1 (pt)
EP (2) EP1077722B1 (pt)
JP (1) JP2002516294A (pt)
AT (1) ATE335510T1 (pt)
AU (1) AU761899B2 (pt)
BR (1) BR9910643A (pt)
CA (1) CA2328894A1 (pt)
CY (1) CY1107337T1 (pt)
DE (1) DE69932717T2 (pt)
DK (2) DK1077722T3 (pt)
ES (2) ES2628744T3 (pt)
HK (1) HK1037125A1 (pt)
IL (2) IL139813A0 (pt)
NZ (1) NZ508927A (pt)
PT (2) PT1077722E (pt)
SI (1) SI1077722T1 (pt)
WO (1) WO1999061056A2 (pt)
ZA (1) ZA200006765B (pt)

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EP1077722B1 (en) 2006-08-09
EP1733735A2 (en) 2006-12-20
PT1733735T (pt) 2017-06-16
DK1077722T3 (da) 2006-11-27
ES2628744T3 (es) 2017-08-03
DK1733735T3 (en) 2017-06-19
JP2002516294A (ja) 2002-06-04
NZ508927A (en) 2003-12-19
US8574599B1 (en) 2013-11-05
WO1999061056A2 (en) 1999-12-02
ZA200006765B (en) 2002-08-22
SI1077722T1 (sl) 2007-02-28
IL139813A0 (en) 2002-02-10
IL139813A (en) 2007-06-03
WO1999061056A9 (en) 2000-06-15
HK1037125A1 (en) 2002-02-01
AU761899B2 (en) 2003-06-12
DE69932717D1 (de) 2006-09-21
ES2272069T3 (es) 2007-04-16
EP1077722A2 (en) 2001-02-28
EP1733735B1 (en) 2017-03-22
US20040266719A1 (en) 2004-12-30
DE69932717T2 (de) 2007-08-09
WO1999061056A3 (en) 2000-04-06
ATE335510T1 (de) 2006-09-15
EP1733735A3 (en) 2008-08-27
AU4197799A (en) 1999-12-13
CY1107337T1 (el) 2012-12-19
CA2328894A1 (en) 1999-12-02

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