BR9906351A - Método para ensaio de anticorpos e dispositivo de ensaio de anticorpo - Google Patents

Método para ensaio de anticorpos e dispositivo de ensaio de anticorpo

Info

Publication number
BR9906351A
BR9906351A BR9906351-4A BR9906351A BR9906351A BR 9906351 A BR9906351 A BR 9906351A BR 9906351 A BR9906351 A BR 9906351A BR 9906351 A BR9906351 A BR 9906351A
Authority
BR
Brazil
Prior art keywords
antibody
region
sample
antibody assay
assay
Prior art date
Application number
BR9906351-4A
Other languages
English (en)
Inventor
Tetsuya Tachikawa
Tetsuya Oda
Shigeo Takahashi
Atsunari Noda
Suguru Akamatsu
Kiyonori Katsuragi
Fusaichi Machikawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10309598A external-priority patent/JPH11295311A/ja
Priority claimed from JP11852498A external-priority patent/JP3493543B2/ja
Priority claimed from JP21884398A external-priority patent/JP3493544B2/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of BR9906351A publication Critical patent/BR9906351A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56916—Enterobacteria, e.g. shigella, salmonella, klebsiella, serratia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/24—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • G01N2333/245—Escherichia (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20—Immunohistochemistry assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Patente de Invenção: <B>"MéTODO PARA ENSAIO DE ANTICORPOS E DISPOSITIVO DE ENSAIO DE ANTICORPO"<D>. A invenção refere-se a uma tecnologia pela qual os anticorpos direcionados às fontes de infecção em fluídos corporais podem ser ensaiados com elevada precisão, conveniência e especificidade. Mais particularmente, a invenção fornece um método de imunoensaio de anticorpo no qual a reação de antígeno-anticorpo entre um anticorpo alvo em uma amostra e um antígeno de ensaio é conduzida na presença de um componente de <MU>E.coli<MV> e um método de ensaio de anticorpo que compreende empregar um reagente tendo uma afinidade específica para a região de Fc de um anticorpo IgG como o reagente de ensaio de anticorpo. A invenção ainda fornece um dispositivo de ensaio de anticorpo compreendendo um suporte de fase sólida tendo pelo menos (a) uma primeira região na qual a amostra é aplicada e (b) uma segunda região onde o anticorpo na amostra é reagido como disposto em uma tal disposição que a amostra é repelida da primeira região para a segunda região e um meio de rotulação para detecção do resultado da reação na segunda região, caracterizado pelo fato de que (b) a segunda região é provida com (i) um sítio de teste no qual um ligante para capturar o anticorpo alvo a ser ensaiado é imobilizado e (ii) um sítio de controle no qual um ligante para capturar um anticorpo arbitrário ocorrendo na amostra, é imobilizado.
BR9906351-4A 1998-04-14 1999-04-09 Método para ensaio de anticorpos e dispositivo de ensaio de anticorpo BR9906351A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP10309598A JPH11295311A (ja) 1998-04-14 1998-04-14 抗体測定方法
JP11852498A JP3493543B2 (ja) 1998-04-28 1998-04-28 抗体測定方法
JP21884398A JP3493544B2 (ja) 1998-08-03 1998-08-03 抗体アッセイ装置
PCT/JP1999/001921 WO1999053318A1 (fr) 1998-04-14 1999-04-09 Procedes de detection d'anticorps et dispositif de detection d'anticorps

Publications (1)

Publication Number Publication Date
BR9906351A true BR9906351A (pt) 2000-09-19

Family

ID=27309889

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9906351-4A BR9906351A (pt) 1998-04-14 1999-04-09 Método para ensaio de anticorpos e dispositivo de ensaio de anticorpo

Country Status (14)

Country Link
US (2) US20020187510A1 (pt)
EP (1) EP0989406B1 (pt)
KR (1) KR100766098B1 (pt)
CN (1) CN1163753C (pt)
AT (1) ATE395598T1 (pt)
AU (1) AU757629B2 (pt)
BR (1) BR9906351A (pt)
CA (1) CA2293677C (pt)
DE (1) DE69938701D1 (pt)
ES (1) ES2306509T3 (pt)
HK (1) HK1027397A1 (pt)
ID (1) ID23440A (pt)
TW (1) TWI250281B (pt)
WO (1) WO1999053318A1 (pt)

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US20030153013A1 (en) * 2002-11-07 2003-08-14 Ruo-Pan Huang Antibody-based protein array system
DE602004022588D1 (de) * 2003-12-24 2009-09-24 Inodiag Verfahren zur serologischen diagnose und bestimmung des immunisierungszustands unter einschluss verschiedener kontrollen
GB2422664A (en) * 2005-01-28 2006-08-02 Ethicon Inc Device for detecting an enzyme in a sample
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CN102887944A (zh) * 2012-09-06 2013-01-23 李克生 一种肺炎衣原体抗原,制备该抗原的方法,利用该抗原检测抗肺炎衣原体抗体的快速检测方法及试剂
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Also Published As

Publication number Publication date
HK1027397A1 (en) 2001-01-12
ATE395598T1 (de) 2008-05-15
CA2293677C (en) 2009-01-27
WO1999053318A1 (fr) 1999-10-21
US20030175699A1 (en) 2003-09-18
TWI250281B (en) 2006-03-01
AU3168799A (en) 1999-11-01
CN1163753C (zh) 2004-08-25
ES2306509T3 (es) 2008-11-01
KR20010013751A (ko) 2001-02-26
EP0989406B1 (en) 2008-05-14
CN1263599A (zh) 2000-08-16
CA2293677A1 (en) 1999-10-21
US20020187510A1 (en) 2002-12-12
ID23440A (id) 2000-04-20
DE69938701D1 (de) 2008-06-26
US7368277B2 (en) 2008-05-06
KR100766098B1 (ko) 2007-10-11
EP0989406A1 (en) 2000-03-29
AU757629B2 (en) 2003-02-27
EP0989406A4 (en) 2004-03-31

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11 E 13 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.