BR9815378B1 - sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório e método de fabricação do mesmo. - Google Patents
sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório e método de fabricação do mesmo.Info
- Publication number
- BR9815378B1 BR9815378B1 BRPI9815378-1A BR9815378A BR9815378B1 BR 9815378 B1 BR9815378 B1 BR 9815378B1 BR 9815378 A BR9815378 A BR 9815378A BR 9815378 B1 BR9815378 B1 BR 9815378B1
- Authority
- BR
- Brazil
- Prior art keywords
- drug delivery
- transdermal drug
- diclofenac
- salt
- delivery system
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019970049084A KR19990026792A (ko) | 1997-09-26 | 1997-09-26 | 디클로페낙 디에틸암모늄염을 함유한 매트릭스형 패취제제 |
PCT/KR1998/000295 WO1999016434A1 (en) | 1997-09-26 | 1998-09-25 | A transdermal drug delivery system for anti-inflammatory analgesic agent comprising diclofenac diethylammonium salt, and the manufacturing method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9815378A BR9815378A (pt) | 2000-11-21 |
BR9815378B1 true BR9815378B1 (pt) | 2010-05-18 |
Family
ID=19521757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9815378-1A BR9815378B1 (pt) | 1997-09-26 | 1998-09-25 | sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório e método de fabricação do mesmo. |
Country Status (13)
Country | Link |
---|---|
US (1) | US6723337B1 (pt) |
EP (1) | EP1030660B1 (pt) |
JP (1) | JP2001517696A (pt) |
KR (2) | KR19990026792A (pt) |
CN (1) | CN1180773C (pt) |
AU (1) | AU726448B2 (pt) |
BR (1) | BR9815378B1 (pt) |
CA (1) | CA2304784C (pt) |
DE (1) | DE69822327T2 (pt) |
ES (1) | ES2213916T3 (pt) |
HK (1) | HK1030161A1 (pt) |
NZ (1) | NZ503112A (pt) |
WO (1) | WO1999016434A1 (pt) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2379147C (en) | 1999-07-15 | 2009-09-01 | Hisamitsu Pharmaceutical Co., Inc. | Percutaneously absorbable preparations |
KR20010026619A (ko) * | 1999-09-08 | 2001-04-06 | 김동회 | 벌레물린 부위 처치용 패취제제 |
JP4653893B2 (ja) * | 2000-01-27 | 2011-03-16 | 純一 須藤 | 二層型経皮吸収製剤 |
KR20010077445A (ko) * | 2000-02-02 | 2001-08-20 | 김윤 | 세라믹이 함유된 매트릭스형 패취제 |
DK1277466T3 (da) | 2000-04-18 | 2011-10-17 | Hisamitsu Pharmaceutical Co | Plaster indeholdende et antiinflammatorisk middel |
US6455067B1 (en) * | 2000-05-24 | 2002-09-24 | Sang-A Pharmaceutical Co., Ltd. | Transdermal patch for nonsteroidal antiinflammatory drug(s) |
KR100363476B1 (ko) * | 2000-06-27 | 2002-12-05 | 대신제약주식회사 | 디크로 페낙 또는 그의 염들을 함유한 경피투과용 경고제 |
DE10032537A1 (de) * | 2000-07-05 | 2002-01-31 | Labtec Gmbh | Dermales System, enthaltend 2-(3-Benzophenyl)Propionsäure |
TWI290464B (en) * | 2000-09-01 | 2007-12-01 | Novartis Consumer Health Sa | Treatment of burns |
DE10049225A1 (de) * | 2000-09-28 | 2002-04-11 | Labtec Gmbh | Dermales System, enthaltend Diclofenac |
KR100406722B1 (ko) * | 2000-11-06 | 2003-11-21 | 주식회사 삼양사 | 수분흡수능이 우수한 매트릭스형 경피투여제 |
KR20020035398A (ko) * | 2000-11-06 | 2002-05-11 | 김윤 | 수지(手指)용 진통 소염 경피투여제 |
DE60236084D1 (de) * | 2001-05-31 | 2010-06-02 | Hisamitsu Pharmaceutical Co | Perkutan resorbierbare pflaster |
US20040258739A1 (en) * | 2001-09-04 | 2004-12-23 | Rudy Susilo | Plaster for the treatment of dysfunctions and disorders of nails |
DE10256774A1 (de) * | 2002-12-05 | 2004-06-24 | Lts Lohmann Therapie-Systeme Ag | Transmucosale und transdermale Arzneimittel mit verbesserter Wirkstoffresorption |
WO2004103338A1 (en) * | 2003-05-19 | 2004-12-02 | Bioprogress Plc | Adhesives and film modifying compositions |
JP4344175B2 (ja) * | 2003-06-13 | 2009-10-14 | リンテック株式会社 | マトリックス型経皮吸収製剤の製造方法 |
JP2005325165A (ja) * | 2004-05-12 | 2005-11-24 | Three M Innovative Properties Co | 100℃以下の温度で溶融塗布可能なヨウ素含有ホットメルト粘着剤および該粘着剤を用いた医療用粘着シート製品 |
CA2583642C (en) | 2004-10-21 | 2013-06-25 | Durect Corporation | Transdermal delivery systems |
US8252320B2 (en) | 2004-10-21 | 2012-08-28 | Durect Corporation | Transdermal delivery system for sufentanil |
CN1895242B (zh) * | 2006-04-13 | 2011-08-31 | 沈阳药科大学 | 双氯芬酸盐的透皮贴剂及制备方法 |
US20090221703A1 (en) | 2006-07-09 | 2009-09-03 | Chongxi Yu | High penetration composition and uses thereof |
US20090238763A1 (en) * | 2006-07-09 | 2009-09-24 | Chongxi Yu | High penetration compositions and uses thereof |
ES2472545T3 (es) | 2006-07-25 | 2014-07-01 | Techfields Biochem Co. Ltd | Profármacos de diclofenaco solubles en agua con carga positiva y con una tasa de penetración en piel muy rápida |
AU2008254748A1 (en) * | 2007-05-18 | 2008-11-27 | Tti Ellebeau, Inc. | Transdermal delivery devices assuring an improved release of an active principle through a biological interface |
US9371284B2 (en) | 2007-06-04 | 2016-06-21 | Techfields Pharma Co., Ltd. | Pro-drugs of NSAIAS with very high skin and membranes penetration rates and their new medicinal uses |
BRPI0812368A2 (pt) * | 2007-06-08 | 2015-02-03 | Samyang Corp | Sistemas de liberação de droga transdérmica do tipo matriz e respectivo método de preparação. |
EP2055298A1 (en) * | 2007-10-30 | 2009-05-06 | Novartis AG | Topical composition |
US8445037B2 (en) * | 2008-10-28 | 2013-05-21 | A. M. Todd Company | Volatile distillate by-product of mint oil that promotes absorption and/or bioavailability of compounds of bio-medical and nutritional interest |
KR20230085223A (ko) | 2008-12-04 | 2023-06-13 | 충시 위 | 고투과력을 가진 조성물 및 이의 적용 |
US8894630B2 (en) | 2009-11-13 | 2014-11-25 | The Invention Science Fund I, Llc | Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject |
US8888761B2 (en) * | 2009-11-13 | 2014-11-18 | The Invention Science Fund I, Llc | Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject |
US8439896B2 (en) * | 2009-11-13 | 2013-05-14 | The Invention Science Fund I, Llc | Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject |
PT2455066T (pt) * | 2010-11-08 | 2018-12-06 | Epitech Group S P A | Preparação farmacológica para utilização tópica contendo n-palmitoil-vanilamida |
WO2012089256A1 (en) * | 2010-12-29 | 2012-07-05 | Pharmafilm S.R.L. | Medicated patch for improved transdermal permeation of diclofenac diethylammonium |
EP2865377B1 (en) * | 2012-06-20 | 2020-10-14 | Hisamitsu Pharmaceutical Co., Inc. | Percutaneous absorption promoter and skin patch comprising same |
WO2014068600A1 (en) | 2012-11-02 | 2014-05-08 | Zydus Technologies Limited | Stable transdermal pharmaceutical drug delivery system comprising diclofenac |
KR102155533B1 (ko) | 2013-02-28 | 2020-09-14 | 도레이 카부시키가이샤 | 복합 반투막 및 그 제조 방법 |
EP3096746B1 (en) * | 2014-01-22 | 2019-03-13 | 4P Therapeutics | Abuse and misuse deterrent transdermal systems |
CN105708823A (zh) * | 2016-04-08 | 2016-06-29 | 中国药科大学 | 一种长效双氯芬酸类透皮贴剂及其制备工艺 |
JP6918543B2 (ja) * | 2017-03-27 | 2021-08-11 | 株式会社アルビオン | 皮膚外用剤または化粧料用組成物 |
US20180311928A1 (en) * | 2017-04-27 | 2018-11-01 | Tesa Se | Adhesive tape for splicing of metal sheets used in high-tension, high temperature processes |
KR20220162136A (ko) * | 2020-03-30 | 2022-12-07 | 산쇼 이야쿠 가부시키가이샤 | 멘톨을 함유하는 조성물 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT380166B (de) * | 1981-02-16 | 1986-04-25 | Ciba Geigy Ag | Verfahren zur herstellung topisch applizierbarer pharmazeutischer praeparate, enthaltend salze von alkancarbonsaeuren |
US4537776A (en) | 1983-06-21 | 1985-08-27 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone |
JPS61280426A (ja) | 1985-06-04 | 1986-12-11 | Ikeda Mohandou:Kk | 消炎鎮痛用貼付剤 |
CH666621A5 (de) * | 1986-06-27 | 1988-08-15 | Ciba Geigy Ag | Topisch applizierbare pharmazeutische zusammensetzungen mit systemischer wirkung. |
IT1223343B (it) * | 1987-11-03 | 1990-09-19 | Also Lab Sas | Formulazioni farmaceutiche per somministrazione transdermica |
US5641504A (en) * | 1988-06-09 | 1997-06-24 | Alza Corporation | Skin permeation enhancer compositions using glycerol monolinoleate |
DE69021511T2 (de) | 1989-11-14 | 1996-11-21 | Beta Pharm Co | Entzündungshemmende Arzneimittel zur äusserlichen Anwendung. |
JP3046346B2 (ja) * | 1990-03-12 | 2000-05-29 | 昭和電工株式会社 | 外用剤基剤又は補助剤とそれを含有する人又は動物の外用剤 |
JP2849937B2 (ja) * | 1990-04-18 | 1999-01-27 | 日東電工株式会社 | 医療用貼付剤 |
US5350769A (en) | 1990-10-30 | 1994-09-27 | Ss Pharmaceutical Co., Ltd. | Antiinflammatory gel preparation |
JPH04193826A (ja) | 1990-11-27 | 1992-07-13 | Shirogane Seiyaku Kk | ジクロフェナクナトリウム含有の経皮吸収型消炎・鎮痛貼布剤 |
PT100502A (pt) | 1991-05-20 | 1993-08-31 | Alza Corp | Composicoes farmaceuticas para aumentar a capacidade de permeacao na pele utilizando monolinoleato de glicerol |
JP3086290B2 (ja) * | 1991-07-26 | 2000-09-11 | エスエス製薬株式会社 | ジクロフェナクナトリウム貼付剤 |
EP0581587A3 (en) * | 1992-07-31 | 1995-05-17 | Tanabe Seiyaku Co | Base material for transdermal administration. |
GB2273044B (en) * | 1992-12-02 | 1997-04-09 | Pacific Chem Co Ltd | Medicinal patches for percutaneous administration |
US5429590A (en) * | 1992-12-01 | 1995-07-04 | Nitto Denko Corporation | Medical water-absorptive polymer and dressing for wound and medical bandage using the same |
JP2523428B2 (ja) | 1992-12-04 | 1996-08-07 | エスエス製薬株式会社 | 消炎鎮痛ゲル製剤 |
TW283648B (pt) * | 1993-01-21 | 1996-08-21 | Yamanouchi Pharma Co Ltd | |
JP3526887B2 (ja) | 1993-04-23 | 2004-05-17 | 帝國製薬株式会社 | 消炎鎮痛外用貼付剤 |
JPH07206710A (ja) * | 1994-01-21 | 1995-08-08 | Nitto Denko Corp | 経皮投薬用テープ製剤 |
-
1997
- 1997-09-26 KR KR1019970049084A patent/KR19990026792A/ko active Search and Examination
-
1998
- 1998-09-04 KR KR1019980036559A patent/KR100305216B1/ko not_active IP Right Cessation
- 1998-09-25 WO PCT/KR1998/000295 patent/WO1999016434A1/en active IP Right Grant
- 1998-09-25 AU AU94647/98A patent/AU726448B2/en not_active Expired
- 1998-09-25 NZ NZ503112A patent/NZ503112A/en not_active IP Right Cessation
- 1998-09-25 DE DE69822327T patent/DE69822327T2/de not_active Expired - Lifetime
- 1998-09-25 EP EP98947969A patent/EP1030660B1/en not_active Expired - Lifetime
- 1998-09-25 ES ES98947969T patent/ES2213916T3/es not_active Expired - Lifetime
- 1998-09-25 US US09/509,303 patent/US6723337B1/en not_active Expired - Lifetime
- 1998-09-25 JP JP2000513570A patent/JP2001517696A/ja active Pending
- 1998-09-25 CN CNB988094738A patent/CN1180773C/zh not_active Expired - Lifetime
- 1998-09-25 BR BRPI9815378-1A patent/BR9815378B1/pt not_active IP Right Cessation
- 1998-09-25 CA CA002304784A patent/CA2304784C/en not_active Expired - Lifetime
-
2001
- 2001-02-21 HK HK01101243A patent/HK1030161A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1999016434A1 (en) | 1999-04-08 |
BR9815378A (pt) | 2000-11-21 |
KR100305216B1 (ko) | 2001-11-30 |
AU726448B2 (en) | 2000-11-09 |
AU9464798A (en) | 1999-04-23 |
JP2001517696A (ja) | 2001-10-09 |
ES2213916T3 (es) | 2004-09-01 |
CA2304784A1 (en) | 1999-04-08 |
CN1271280A (zh) | 2000-10-25 |
HK1030161A1 (en) | 2001-04-27 |
EP1030660B1 (en) | 2004-03-10 |
CN1180773C (zh) | 2004-12-22 |
DE69822327T2 (de) | 2005-03-17 |
KR19990029556A (ko) | 1999-04-26 |
DE69822327D1 (de) | 2004-04-15 |
KR19990026792A (ko) | 1999-04-15 |
NZ503112A (en) | 2002-02-01 |
US6723337B1 (en) | 2004-04-20 |
EP1030660A1 (en) | 2000-08-30 |
CA2304784C (en) | 2003-04-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
B11N | Dismissal: publication cancelled [chapter 11.14 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 18/05/2010, OBSERVADAS AS CONDICOES LEGAIS. |
|
B25D | Requested change of name of applicant approved |
Owner name: SAMYANG CORPORATION (KR) |
|
B25D | Requested change of name of applicant approved |
Owner name: SAMYANG HOLDINGS CORPORATION (KR) |
|
B25A | Requested transfer of rights approved |
Owner name: SAMYANG BIOPHARMACEUTICALS CORPORATION (KR) |
|
B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 18.05.2020 |