BR9815378A - Sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório compreendendo sal de dietilamÈnio diclofenac e o método de fabricação do mesmo. - Google Patents
Sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório compreendendo sal de dietilamÈnio diclofenac e o método de fabricação do mesmo.Info
- Publication number
- BR9815378A BR9815378A BR9815378-1A BR9815378A BR9815378A BR 9815378 A BR9815378 A BR 9815378A BR 9815378 A BR9815378 A BR 9815378A BR 9815378 A BR9815378 A BR 9815378A
- Authority
- BR
- Brazil
- Prior art keywords
- diclofenac
- transdermal drug
- analgesic agent
- manufacturing
- inflammatory analgesic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
<B>SISTEMA DE FORNECIMENTO DE DROGA TRANSDéRMICO PARA AGENTE ANALGéSICO ANTIINFLAMATóRIO COMPREENDENDO SAL DE DIETILAMÈNIO DICLOFENAC, E O MéTODO DE FABRICAçãO DO MESMO<D> A invenção refere-se a um sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório compreendendo sal de dietilamónio diclofenac, onde uma película de forro (1), uma camada de matriz (2) contendo ingredientes ativos, um revestimento de liberação (3), que é retirado antes da aplicação sobre a pele, são laminados no mesmo. Mais particularmente, a presente invenção refere-se a um sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório compreendendo sal de dietilamónio diclofenac, onde a penetração e adesão transdérmica da placa ao corpo são aumentadas por meio de uma camada de matriz que compreende um sal de dietilamónio diclofenac como ingrediente ativo além de polímero acrílico como constituinte adesivo, agente tensoativo não iónico como intensificador de absorção, terpeno e meio auxiliar de dissolução, e os constituintes volátil e não volátil da composição são aplicados separadamente no mesmo para reduzir, de modo significativo, o tempo de fabricação do mesmo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019970049084A KR19990026792A (ko) | 1997-09-26 | 1997-09-26 | 디클로페낙 디에틸암모늄염을 함유한 매트릭스형 패취제제 |
PCT/KR1998/000295 WO1999016434A1 (en) | 1997-09-26 | 1998-09-25 | A transdermal drug delivery system for anti-inflammatory analgesic agent comprising diclofenac diethylammonium salt, and the manufacturing method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9815378A true BR9815378A (pt) | 2000-11-21 |
BR9815378B1 BR9815378B1 (pt) | 2010-05-18 |
Family
ID=19521757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9815378-1A BR9815378B1 (pt) | 1997-09-26 | 1998-09-25 | sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório e método de fabricação do mesmo. |
Country Status (13)
Country | Link |
---|---|
US (1) | US6723337B1 (pt) |
EP (1) | EP1030660B1 (pt) |
JP (1) | JP2001517696A (pt) |
KR (2) | KR19990026792A (pt) |
CN (1) | CN1180773C (pt) |
AU (1) | AU726448B2 (pt) |
BR (1) | BR9815378B1 (pt) |
CA (1) | CA2304784C (pt) |
DE (1) | DE69822327T2 (pt) |
ES (1) | ES2213916T3 (pt) |
HK (1) | HK1030161A1 (pt) |
NZ (1) | NZ503112A (pt) |
WO (1) | WO1999016434A1 (pt) |
Families Citing this family (43)
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CN1361686A (zh) * | 1999-07-15 | 2002-07-31 | 久光制药株式会社 | 经皮吸收制剂 |
KR20010026619A (ko) * | 1999-09-08 | 2001-04-06 | 김동회 | 벌레물린 부위 처치용 패취제제 |
JP4653893B2 (ja) * | 2000-01-27 | 2011-03-16 | 純一 須藤 | 二層型経皮吸収製剤 |
KR20010077445A (ko) * | 2000-02-02 | 2001-08-20 | 김윤 | 세라믹이 함유된 매트릭스형 패취제 |
ATE517614T1 (de) | 2000-04-18 | 2011-08-15 | Hisamitsu Pharmaceutical Co | Pflaster enthaltend einen anti-inflammatorischen wirkstoff |
US6455067B1 (en) * | 2000-05-24 | 2002-09-24 | Sang-A Pharmaceutical Co., Ltd. | Transdermal patch for nonsteroidal antiinflammatory drug(s) |
KR100363476B1 (ko) * | 2000-06-27 | 2002-12-05 | 대신제약주식회사 | 디크로 페낙 또는 그의 염들을 함유한 경피투과용 경고제 |
DE10032537A1 (de) * | 2000-07-05 | 2002-01-31 | Labtec Gmbh | Dermales System, enthaltend 2-(3-Benzophenyl)Propionsäure |
TWI290464B (en) * | 2000-09-01 | 2007-12-01 | Novartis Consumer Health Sa | Treatment of burns |
DE10049225A1 (de) * | 2000-09-28 | 2002-04-11 | Labtec Gmbh | Dermales System, enthaltend Diclofenac |
KR20020035398A (ko) * | 2000-11-06 | 2002-05-11 | 김윤 | 수지(手指)용 진통 소염 경피투여제 |
CN100340237C (zh) * | 2000-11-06 | 2007-10-03 | 株式会社三养社 | 吸水性和粘附性能改善的经皮给药系统 |
ATE464887T1 (de) * | 2001-05-31 | 2010-05-15 | Hisamitsu Pharmaceutical Co | Perkutan resorbierbare pflaster |
IL160551A0 (en) * | 2001-09-04 | 2004-07-25 | Trommsdorff Arzneimittel | Plaster for the treatment of dysfunctions and disorders of nails |
DE10256774A1 (de) * | 2002-12-05 | 2004-06-24 | Lts Lohmann Therapie-Systeme Ag | Transmucosale und transdermale Arzneimittel mit verbesserter Wirkstoffresorption |
WO2004103338A1 (en) * | 2003-05-19 | 2004-12-02 | Bioprogress Plc | Adhesives and film modifying compositions |
JP4344175B2 (ja) * | 2003-06-13 | 2009-10-14 | リンテック株式会社 | マトリックス型経皮吸収製剤の製造方法 |
JP2005325165A (ja) * | 2004-05-12 | 2005-11-24 | Three M Innovative Properties Co | 100℃以下の温度で溶融塗布可能なヨウ素含有ホットメルト粘着剤および該粘着剤を用いた医療用粘着シート製品 |
PL1814531T3 (pl) | 2004-10-21 | 2010-11-30 | Durect Corp | Transdermalne systemy dostarczania |
US8252319B2 (en) | 2004-10-21 | 2012-08-28 | Durect Corporation | Transdermal delivery system for sufentanil |
CN1895242B (zh) * | 2006-04-13 | 2011-08-31 | 沈阳药科大学 | 双氯芬酸盐的透皮贴剂及制备方法 |
WO2008012602A1 (en) | 2006-07-25 | 2008-01-31 | Techfields Biochem Co. Ltd | Positively charged water-soluble prodrugs of diclofenac with very fast skin penetration rate |
US20090221703A1 (en) | 2006-07-09 | 2009-09-03 | Chongxi Yu | High penetration composition and uses thereof |
US20090238763A1 (en) | 2006-07-09 | 2009-09-24 | Chongxi Yu | High penetration compositions and uses thereof |
RU2482841C2 (ru) * | 2007-05-18 | 2013-05-27 | ТиТиАй Эллебо, Инк. | Устройства для трансдермальной доставки, обеспечивающие улучшенное высвобождение действующего начала через биологическую поверхность |
KR20190091378A (ko) * | 2007-06-04 | 2019-08-05 | 테크필즈 인크 | 매우 높은 피부 및 막 침투율을 가지는 비스테로이드성 소염제(nsaia) 약물전구체 및 이들의 새로운 의약적 용도 |
KR101000945B1 (ko) * | 2007-06-08 | 2010-12-13 | 주식회사 삼양사 | 매트릭스형 경피투여제 및 이의 제조방법 |
EP2055298A1 (en) * | 2007-10-30 | 2009-05-06 | Novartis AG | Topical composition |
US8445037B2 (en) * | 2008-10-28 | 2013-05-21 | A. M. Todd Company | Volatile distillate by-product of mint oil that promotes absorption and/or bioavailability of compounds of bio-medical and nutritional interest |
KR20210123406A (ko) | 2008-12-04 | 2021-10-13 | 충시 위 | 고투과력을 가진 조성물 및 이의 적용 |
US8894630B2 (en) | 2009-11-13 | 2014-11-25 | The Invention Science Fund I, Llc | Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject |
US9078863B2 (en) * | 2009-11-13 | 2015-07-14 | The Invention Science Fund I, Llc | Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject |
US8439896B2 (en) * | 2009-11-13 | 2013-05-14 | The Invention Science Fund I, Llc | Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject |
PT2455066T (pt) * | 2010-11-08 | 2018-12-06 | Epitech Group S P A | Preparação farmacológica para utilização tópica contendo n-palmitoil-vanilamida |
EP2658576A1 (en) * | 2010-12-29 | 2013-11-06 | Pharmafilm S.R.L. | Medicated patch for improved transdermal permeation of diclofenac diethylammonium |
US20150231255A1 (en) * | 2012-06-20 | 2015-08-20 | Hisamitsu Pharmaceutical Co., Inc. | Absorption promoting agent and patch comprising same |
WO2014068600A1 (en) | 2012-11-02 | 2014-05-08 | Zydus Technologies Limited | Stable transdermal pharmaceutical drug delivery system comprising diclofenac |
US10427109B2 (en) | 2013-02-28 | 2019-10-01 | Toray Industries, Inc. | Composite semipermeable membrane and production thereof |
ES2729871T3 (es) * | 2014-01-22 | 2019-11-06 | 4P Therapeutics | Sistemas transdérmicos disuasivos del abuso y del mal uso |
CN105708823A (zh) * | 2016-04-08 | 2016-06-29 | 中国药科大学 | 一种长效双氯芬酸类透皮贴剂及其制备工艺 |
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US20180311928A1 (en) * | 2017-04-27 | 2018-11-01 | Tesa Se | Adhesive tape for splicing of metal sheets used in high-tension, high temperature processes |
EP4129275A4 (en) * | 2020-03-30 | 2023-11-22 | Sunsho Pharmaceutical Co., Ltd. | COMPOSITION CONTAINING A MENTHOL |
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EP0581587A3 (en) * | 1992-07-31 | 1995-05-17 | Tanabe Seiyaku Co | Base material for transdermal administration. |
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US5429590A (en) * | 1992-12-01 | 1995-07-04 | Nitto Denko Corporation | Medical water-absorptive polymer and dressing for wound and medical bandage using the same |
JP2523428B2 (ja) | 1992-12-04 | 1996-08-07 | エスエス製薬株式会社 | 消炎鎮痛ゲル製剤 |
WO1994016682A1 (en) * | 1993-01-21 | 1994-08-04 | Yamanouchi Pharmaceutical Co., Ltd. | Novel, percutaneously absorbable preparation |
JP3526887B2 (ja) | 1993-04-23 | 2004-05-17 | 帝國製薬株式会社 | 消炎鎮痛外用貼付剤 |
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-
1997
- 1997-09-26 KR KR1019970049084A patent/KR19990026792A/ko active Search and Examination
-
1998
- 1998-09-04 KR KR1019980036559A patent/KR100305216B1/ko not_active IP Right Cessation
- 1998-09-25 DE DE69822327T patent/DE69822327T2/de not_active Expired - Lifetime
- 1998-09-25 JP JP2000513570A patent/JP2001517696A/ja active Pending
- 1998-09-25 ES ES98947969T patent/ES2213916T3/es not_active Expired - Lifetime
- 1998-09-25 BR BRPI9815378-1A patent/BR9815378B1/pt not_active IP Right Cessation
- 1998-09-25 CN CNB988094738A patent/CN1180773C/zh not_active Expired - Lifetime
- 1998-09-25 US US09/509,303 patent/US6723337B1/en not_active Expired - Lifetime
- 1998-09-25 AU AU94647/98A patent/AU726448B2/en not_active Expired
- 1998-09-25 WO PCT/KR1998/000295 patent/WO1999016434A1/en active IP Right Grant
- 1998-09-25 EP EP98947969A patent/EP1030660B1/en not_active Expired - Lifetime
- 1998-09-25 CA CA002304784A patent/CA2304784C/en not_active Expired - Lifetime
- 1998-09-25 NZ NZ503112A patent/NZ503112A/en not_active IP Right Cessation
-
2001
- 2001-02-21 HK HK01101243A patent/HK1030161A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR19990026792A (ko) | 1999-04-15 |
EP1030660B1 (en) | 2004-03-10 |
HK1030161A1 (en) | 2001-04-27 |
BR9815378B1 (pt) | 2010-05-18 |
WO1999016434A1 (en) | 1999-04-08 |
ES2213916T3 (es) | 2004-09-01 |
AU726448B2 (en) | 2000-11-09 |
CA2304784A1 (en) | 1999-04-08 |
CN1271280A (zh) | 2000-10-25 |
DE69822327D1 (de) | 2004-04-15 |
CN1180773C (zh) | 2004-12-22 |
EP1030660A1 (en) | 2000-08-30 |
CA2304784C (en) | 2003-04-22 |
AU9464798A (en) | 1999-04-23 |
NZ503112A (en) | 2002-02-01 |
KR19990029556A (ko) | 1999-04-26 |
DE69822327T2 (de) | 2005-03-17 |
JP2001517696A (ja) | 2001-10-09 |
KR100305216B1 (ko) | 2001-11-30 |
US6723337B1 (en) | 2004-04-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
B11N | Dismissal: publication cancelled [chapter 11.14 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
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