BR9815378A - Sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório compreendendo sal de dietilamÈnio diclofenac e o método de fabricação do mesmo. - Google Patents

Sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório compreendendo sal de dietilamÈnio diclofenac e o método de fabricação do mesmo.

Info

Publication number
BR9815378A
BR9815378A BR9815378-1A BR9815378A BR9815378A BR 9815378 A BR9815378 A BR 9815378A BR 9815378 A BR9815378 A BR 9815378A BR 9815378 A BR9815378 A BR 9815378A
Authority
BR
Brazil
Prior art keywords
diclofenac
transdermal drug
analgesic agent
manufacturing
inflammatory analgesic
Prior art date
Application number
BR9815378-1A
Other languages
English (en)
Other versions
BR9815378B1 (pt
Inventor
Jin Deog Song
Original Assignee
Sam Yang Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sam Yang Co filed Critical Sam Yang Co
Publication of BR9815378A publication Critical patent/BR9815378A/pt
Publication of BR9815378B1 publication Critical patent/BR9815378B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

<B>SISTEMA DE FORNECIMENTO DE DROGA TRANSDéRMICO PARA AGENTE ANALGéSICO ANTIINFLAMATóRIO COMPREENDENDO SAL DE DIETILAMÈNIO DICLOFENAC, E O MéTODO DE FABRICAçãO DO MESMO<D> A invenção refere-se a um sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório compreendendo sal de dietilamónio diclofenac, onde uma película de forro (1), uma camada de matriz (2) contendo ingredientes ativos, um revestimento de liberação (3), que é retirado antes da aplicação sobre a pele, são laminados no mesmo. Mais particularmente, a presente invenção refere-se a um sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório compreendendo sal de dietilamónio diclofenac, onde a penetração e adesão transdérmica da placa ao corpo são aumentadas por meio de uma camada de matriz que compreende um sal de dietilamónio diclofenac como ingrediente ativo além de polímero acrílico como constituinte adesivo, agente tensoativo não iónico como intensificador de absorção, terpeno e meio auxiliar de dissolução, e os constituintes volátil e não volátil da composição são aplicados separadamente no mesmo para reduzir, de modo significativo, o tempo de fabricação do mesmo.
BRPI9815378-1A 1997-09-26 1998-09-25 sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório e método de fabricação do mesmo. BR9815378B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019970049084A KR19990026792A (ko) 1997-09-26 1997-09-26 디클로페낙 디에틸암모늄염을 함유한 매트릭스형 패취제제
PCT/KR1998/000295 WO1999016434A1 (en) 1997-09-26 1998-09-25 A transdermal drug delivery system for anti-inflammatory analgesic agent comprising diclofenac diethylammonium salt, and the manufacturing method thereof

Publications (2)

Publication Number Publication Date
BR9815378A true BR9815378A (pt) 2000-11-21
BR9815378B1 BR9815378B1 (pt) 2010-05-18

Family

ID=19521757

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9815378-1A BR9815378B1 (pt) 1997-09-26 1998-09-25 sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório e método de fabricação do mesmo.

Country Status (13)

Country Link
US (1) US6723337B1 (pt)
EP (1) EP1030660B1 (pt)
JP (1) JP2001517696A (pt)
KR (2) KR19990026792A (pt)
CN (1) CN1180773C (pt)
AU (1) AU726448B2 (pt)
BR (1) BR9815378B1 (pt)
CA (1) CA2304784C (pt)
DE (1) DE69822327T2 (pt)
ES (1) ES2213916T3 (pt)
HK (1) HK1030161A1 (pt)
NZ (1) NZ503112A (pt)
WO (1) WO1999016434A1 (pt)

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Also Published As

Publication number Publication date
AU9464798A (en) 1999-04-23
AU726448B2 (en) 2000-11-09
CN1271280A (zh) 2000-10-25
DE69822327D1 (de) 2004-04-15
DE69822327T2 (de) 2005-03-17
KR100305216B1 (ko) 2001-11-30
EP1030660B1 (en) 2004-03-10
US6723337B1 (en) 2004-04-20
NZ503112A (en) 2002-02-01
HK1030161A1 (en) 2001-04-27
CN1180773C (zh) 2004-12-22
ES2213916T3 (es) 2004-09-01
CA2304784A1 (en) 1999-04-08
WO1999016434A1 (en) 1999-04-08
KR19990029556A (ko) 1999-04-26
BR9815378B1 (pt) 2010-05-18
CA2304784C (en) 2003-04-22
KR19990026792A (ko) 1999-04-15
EP1030660A1 (en) 2000-08-30
JP2001517696A (ja) 2001-10-09

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11N Dismissal: publication cancelled [chapter 11.14 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 18/05/2010, OBSERVADAS AS CONDICOES LEGAIS.

B25D Requested change of name of applicant approved

Owner name: SAMYANG CORPORATION (KR)

B25D Requested change of name of applicant approved

Owner name: SAMYANG HOLDINGS CORPORATION (KR)

B25A Requested transfer of rights approved

Owner name: SAMYANG BIOPHARMACEUTICALS CORPORATION (KR)

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 18.05.2020